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Volumn 84, Issue 1, 2013, Pages 130-137

Uromodulin upregulates TRPV5 by impairing caveolin-mediated endocytosis

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CAVEOLIN 1; TAMM HORSFALL GLYCOPROTEIN; VANILLOID RECEPTOR 5; VANILLOID RECEPTOR 6;

EID: 84879692778     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2013.63     Document Type: Article
Times cited : (57)

References (49)
  • 1
    • 78651023652 scopus 로고
    • Characterization and separation of an inhibitor of viral hemagglutination present in urine
    • Tamm I, Horsfall FL Jr. Characterization and separation of an inhibitor of viral hemagglutination present in urine. Proc Soc Exp Biol Med 1950; 74: 106-108.
    • (1950) Proc Soc Exp Biol Med , vol.74 , pp. 106-108
    • Tamm, I.1    Horsfall R. J, F.L.2
  • 2
    • 0023113789 scopus 로고
    • Identification of human uromodulin as the Tamm-Horsfall urinary glycoprotein
    • Pennica D, Kohr WJ, Kuang WJ et al. Identification of human uromodulin as the Tamm-Horsfall urinary glycoprotein. Science 1987; 236: 83-88.
    • (1987) Science , vol.236 , pp. 83-88
    • Pennica, D.1    Kohr, W.J.2    Kuang, W.J.3
  • 3
    • 42749083339 scopus 로고    scopus 로고
    • Urinary uromodulin carries an intact ZP domain generated by a conserved C-terminal proteolytic cleavage
    • Santambrogio S, Cattaneo A, Bernascone I et al. Urinary uromodulin carries an intact ZP domain generated by a conserved C-terminal proteolytic cleavage. Biochem Biophys Res Commun 2008; 370: 410-413.
    • (2008) Biochem Biophys Res Commun , vol.370 , pp. 410-413
    • Santambrogio, S.1    Cattaneo, A.2    Bernascone, I.3
  • 4
    • 0025042848 scopus 로고
    • Tamm-Horsfall protein-mRNA synthesis is localized to the thick ascending limb of Henle's loop in rat kidney
    • 1990
    • Bachmann S, Metzger R, Bunnemann B. Tamm-Horsfall protein-mRNA synthesis is localized to the thick ascending limb of Henle's loop in rat kidney. Histochemistry 1990; 94: 517-523 1990.
    • (1990) Histochemistry , vol.94 , pp. 517-523
    • Bachmann, S.1    Metzger, R.2    Bunnemann, B.3
  • 5
    • 0036914069 scopus 로고    scopus 로고
    • Mutations of the UMOD gene are responsible for medullary cystic kidney disease 2 and familial juvenile hyperuricaemic nephropathy
    • Hart TC, Gorry MC, Hart PS et al. Mutations of the UMOD gene are responsible for medullary cystic kidney disease 2 and familial juvenile hyperuricaemic nephropathy. J Med Genet 2002; 39: 882-892.
    • (2002) J Med Genet , vol.39 , pp. 882-892
    • Hart, T.C.1    Gorry, M.C.2    Hart, P.S.3
  • 6
    • 10744226387 scopus 로고    scopus 로고
    • A cluster of mutations in the UMOD gene causes familial juvenile hyperuricemic nephropathy with abnormal expression of Uromodulin
    • Dahan K, Devuyst O, Smaers M et al. A cluster of mutations in the UMOD gene causes familial juvenile hyperuricemic nephropathy with abnormal expression of Uromodulin. J Am Soc Nephrol 2003; 14: 2883-2893.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 2883-2893
    • Dahan, K.1    Devuyst, O.2    Smaers, M.3
  • 7
    • 0346752171 scopus 로고    scopus 로고
    • Allelism of MCKD, FJHN, and GCKD caused by impairment of uromodulin export dynamics
    • Rampoldi L, Caridi G, Santon D et al. Allelism of MCKD, FJHN, and GCKD caused by impairment of uromodulin export dynamics. Hum Mol Genet 2003; 12: 3369-3384.
    • (2003) Hum Mol Genet , vol.12 , pp. 3369-3384
    • Rampoldi, L.1    Caridi, G.2    Santon, D.3
  • 8
    • 10744224657 scopus 로고    scopus 로고
    • Mutations of the Uromodulin gene in MCKD type 2 patients cluster in exon 4 which encodes three EGF-like domains
    • Wolf MT, Mucha BE, Attanasio M et al. Mutations of the Uromodulin gene in MCKD type 2 patients cluster in exon 4 which encodes three EGF-like domains. Kidney Int 2003; 64: 1580-1587.
    • (2003) Kidney Int , vol.64 , pp. 1580-1587
    • Wolf, M.T.1    Mucha, B.E.2    Attanasio, M.3
  • 9
    • 33749532096 scopus 로고    scopus 로고
    • Defective intracellular trafficking of uromodulin mutant isoforms
    • Bernascone I, Vavassori S, Di Pentima A et al. Defective intracellular trafficking of uromodulin mutant isoforms. Traffic 2006; 7: 1567-1579.
    • (2006) Traffic , vol.7 , pp. 1567-1579
    • Bernascone, I.1    Vavassori, S.2    Di Pentima, A.3
  • 10
    • 33645258309 scopus 로고    scopus 로고
    • Mutant tamm-horsfall glycoprotein accumulation in endoplasmic reticulum induces apoptosis reversed by colchicine and sodium 4-phenylbutyrate
    • Choi SW, Ryu OH, Choi SJ et al. Mutant tamm-horsfall glycoprotein accumulation in endoplasmic reticulum induces apoptosis reversed by colchicine and sodium 4-phenylbutyrate. J Am Soc Nephrol 2005; 16: 3006-3014.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 3006-3014
    • Choi, S.W.1    Ryu, O.H.2    Choi, S.J.3
  • 11
    • 77957326576 scopus 로고    scopus 로고
    • Association of variants at UMOD with chronic kidney disease and kidney stones-role of age and comorbid diseases
    • Gudbjartsson DF, Holm H, Indridason OS et al. Association of variants at UMOD with chronic kidney disease and kidney stones-role of age and comorbid diseases. PLoS Genet 2010; 6: e1001039.
    • (2010) PLoS Genet , vol.6
    • Gudbjartsson, D.F.1    Holm, H.2    Indridason, O.S.3
  • 12
    • 4344664015 scopus 로고    scopus 로고
    • Tamm-Horsfall protein is a critical renal defense factor protecting against calcium oxalate crystal formation
    • Mo L, Huang HY, Zhu XH et al. Tamm-Horsfall protein is a critical renal defense factor protecting against calcium oxalate crystal formation. Kidney Int 2004; 66: 1159-1166.
    • (2004) Kidney Int , vol.66 , pp. 1159-1166
    • Mo, L.1    Huang, H.Y.2    Zhu, X.H.3
  • 13
    • 77956458124 scopus 로고    scopus 로고
    • Progressive renal papillary calcification and ureteral stone formation in mice deficient for Tamm-Horsfall protein
    • Liu Y, Mo L, Goldfarb DS et al. Progressive renal papillary calcification and ureteral stone formation in mice deficient for Tamm-Horsfall protein. Am J Physiol Renal Physiol 2010; 299: F469-F478.
    • (2010) Am J Physiol Renal Physiol , vol.299
    • Liu, Y.1    Mo, L.2    Goldfarb, D.S.3
  • 14
    • 70350721790 scopus 로고    scopus 로고
    • Novel missense mutation of uromodulin in mice causes renal dysfunction with alterations in urea handling, energy and bone metabolism
    • Kemter E, Rathkolb B, Rozman J et al. Novel missense mutation of uromodulin in mice causes renal dysfunction with alterations in urea handling, energy and bone metabolism. Am J Physiol Renal Physiol 2009; 297: F1391-F1398.
    • (2009) Am J Physiol Renal Physiol , vol.297
    • Kemter, E.1    Rathkolb, B.2    Rozman, J.3
  • 15
    • 77958171631 scopus 로고    scopus 로고
    • A transgenic mouse model for uromodulin-associated kidney diseases shows specific tubulo-interstitial damage, urinary concentrating defect and renal failure
    • Bernascone I, Janas S, Ikehata M et al. A transgenic mouse model for uromodulin-associated kidney diseases shows specific tubulo-interstitial damage, urinary concentrating defect and renal failure. Hum Mol Genet 2010; 19: 2998-3010.
    • (2010) Hum Mol Genet , vol.19 , pp. 2998-3010
    • Bernascone, I.1    Janas, S.2    Ikehata, M.3
  • 16
    • 79551529059 scopus 로고    scopus 로고
    • Pharmacotherapy of urolithiasis: Evidence from clinical trials
    • Moe OW, Pearle MS, Sakhaee K. Pharmacotherapy of urolithiasis: evidence from clinical trials. Kidney Int 2011; 79: 385-392.
    • (2011) Kidney Int , vol.79 , pp. 385-392
    • Moe, O.W.1    Pearle, M.S.2    Sakhaee, K.3
  • 17
    • 0037379519 scopus 로고    scopus 로고
    • Molecular mechanisms of primary hypercalciuria
    • Frick KK, Bushinsky DA. Molecular mechanisms of primary hypercalciuria. J Am Soc Nephrol 2003; 14: 1082-1095.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1082-1095
    • Frick, K.K.1    Bushinsky, D.A.2
  • 18
    • 33748092345 scopus 로고    scopus 로고
    • Protein regulation of intrarenal crystallization
    • Kumar V, Lieske JC. Protein regulation of intrarenal crystallization. Curr Opin Nephrol Hypertens 2006; 15: 374-380.
    • (2006) Curr Opin Nephrol Hypertens , vol.15 , pp. 374-380
    • Kumar, V.1    Lieske, J.C.2
  • 19
    • 31644446802 scopus 로고    scopus 로고
    • Urinary macromolecular inhibition of crystal adhesion to renal epithelial cells is impaired in male stone formers
    • Kumar V, Peña de la Vega L, Farell G et al. Urinary macromolecular inhibition of crystal adhesion to renal epithelial cells is impaired in male stone formers. Kidney Int 2005; 68: 1784-1792.
    • (2005) Kidney Int , vol.68 , pp. 1784-1792
    • Kumar, V.1    De La Vega, L.P.2    Farell, G.3
  • 20
    • 0024377786 scopus 로고
    • Inhibition of calcium oxalate monohydrate crystal aggregation by urine proteins
    • Hess B, Nakagawa Y, Coe FL. Inhibition of calcium oxalate monohydrate crystal aggregation by urine proteins. Am J Physiol 1989; 257: F99-106.
    • (1989) Am J Physiol , vol.257
    • Hess, B.1    Nakagawa, Y.2    Coe, F.L.3
  • 21
    • 40349085773 scopus 로고    scopus 로고
    • Calciotropic and magnesiotropic TRP channels
    • Hoenderop JG, Bindels RJ. Calciotropic and magnesiotropic TRP channels. Physiology 2008; 23: 32-40.
    • (2008) Physiology , vol.23 , pp. 32-40
    • Hoenderop, J.G.1    Bindels, R.J.2
  • 22
    • 0029412084 scopus 로고
    • Calbindin-D28K facilitates cytosolic calcium diffusion without interfering with calcium signaling
    • Koster HP, Hartog A, Van Os CH et al. Calbindin-D28K facilitates cytosolic calcium diffusion without interfering with calcium signaling. Cell Calcium 1995; 18: 187-196.
    • (1995) Cell Calcium , vol.18 , pp. 187-196
    • Koster, H.P.1    Hartog, A.2    Van Os, C.H.3
  • 23
    • 0034046343 scopus 로고    scopus 로고
    • Localization of the epithelial Ca(2+) channel in rabbit kidney and intestine
    • Hoenderop JG, Hartog A, Stuiver M et al. Localization of the epithelial Ca(2+) channel in rabbit kidney and intestine. J Am Soc Nephrol 2000; 11: 1171-1178.
    • (2000) J Am Soc Nephrol , vol.11 , pp. 1171-1178
    • Hoenderop, J.G.1    Hartog, A.2    Stuiver, M.3
  • 24
    • 0033529713 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a channel-like transporter mediating intestinal calcium absorption
    • Peng JB, Chen XZ, Berger UV et al. Molecular cloning and characterization of a channel-like transporter mediating intestinal calcium absorption. J Biol Chem 1999; 274: 22739-22746.
    • (1999) J Biol Chem , vol.274 , pp. 22739-22746
    • Peng, J.B.1    Chen, X.Z.2    Berger, U.V.3
  • 25
    • 11144232016 scopus 로고    scopus 로고
    • Molecular determinants in TRPV5 channel assembly
    • Chang Q, Gyftogianni E, van de Graaf SF et al. Molecular determinants in TRPV5 channel assembly. J Biol Chem 2004; 279: 54304-54311.
    • (2004) J Biol Chem , vol.279 , pp. 54304-54311
    • Chang, Q.1    Gyftogianni, E.2    Van De Graaf, S.F.3
  • 26
    • 0142151764 scopus 로고    scopus 로고
    • Localization and regulation of the epithelial Ca2+ channel TRPV6 in the kidney
    • Nijenhuis T, Hoenderop JG, van der Kemp AW et al. Localization and regulation of the epithelial Ca2+ channel TRPV6 in the kidney. J Am Soc Nephrol 2003; 14: 2731-2740.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 2731-2740
    • Nijenhuis, T.1    Hoenderop, J.G.2    Van Der Kemp, A.W.3
  • 27
    • 45149092407 scopus 로고    scopus 로고
    • Protein kinase C inhibits caveolae-mediated endocytosis of TRPV5
    • Cha SK, Wu T, Huang CL. Protein kinase C inhibits caveolae-mediated endocytosis of TRPV5. Am J Physiol Renal Physiol 2008; 294: F1212-F1221.
    • (2008) Am J Physiol Renal Physiol , vol.294
    • Cha, S.K.1    Wu, T.2    Huang, C.L.3
  • 28
    • 47749148805 scopus 로고    scopus 로고
    • Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1
    • Cha SK, Ortega B, Kurosu H et al. Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1. Proc Natl Acad Sci USA 2008; 105: 9805-9810.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 9805-9810
    • Cha, S.K.1    Ortega, B.2    Kurosu, H.3
  • 30
    • 4344575076 scopus 로고    scopus 로고
    • Mutations in the uromodulin gene decrease urinary excretion of Tamm-Horsfall protein
    • Bleyer AJ, Hart TC, Shihabi Z et al. Mutations in the uromodulin gene decrease urinary excretion of Tamm-Horsfall protein. Kidney Int 2004; 66: 974-977.
    • (2004) Kidney Int , vol.66 , pp. 974-977
    • Bleyer, A.J.1    Hart, T.C.2    Shihabi, Z.3
  • 31
    • 33947128725 scopus 로고    scopus 로고
    • The Uromodulin C744G mutation causes MCKD2 and FJHN in children and adults and may be due to a possible founder effect
    • Wolf MTF, Beck BB, Misselwitz J et al. The Uromodulin C744G mutation causes MCKD2 and FJHN in children and adults and may be due to a possible founder effect. Kidney Int 2007; 71: 574-581.
    • (2007) Kidney Int , vol.71 , pp. 574-581
    • Wolf, M.T.F.1    Beck, B.B.2    Misselwitz, J.3
  • 32
    • 84859355241 scopus 로고    scopus 로고
    • Urinary secretion and extracellular aggregation of mutant uromodulin isoforms
    • Schaeffer C, Cattaneo A, Trudu M et al. Urinary secretion and extracellular aggregation of mutant uromodulin isoforms. Kidney Int 2012; 81: 769-778.
    • (2012) Kidney Int , vol.81 , pp. 769-778
    • Schaeffer, C.1    Cattaneo, A.2    Trudu, M.3
  • 33
    • 8644278111 scopus 로고    scopus 로고
    • Effect of thiazide on renal gene expression of apical calcium channels and calbindins
    • Lee CT, Shang S, Lai LW et al. Effect of thiazide on renal gene expression of apical calcium channels and calbindins. Am J Physiol Renal Physiol 2004; 287: F1164-F1170.
    • (2004) Am J Physiol Renal Physiol , vol.287
    • Lee, C.T.1    Shang, S.2    Lai, L.W.3
  • 35
    • 1342322652 scopus 로고    scopus 로고
    • Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: Rapid communication
    • Bates JM, Raffi HM, Prasadan K et al. Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication. Kidney Int 2004; 65: 791-797.
    • (2004) Kidney Int , vol.65 , pp. 791-797
    • Bates, J.M.1    Raffi, H.M.2    Prasadan, K.3
  • 36
    • 0036430087 scopus 로고    scopus 로고
    • Binding of Tamm-Horsfall protein to complement 1q and complement 1, including influence of hydrogen-ion concentration
    • Rhodes DCJ. Binding of Tamm-Horsfall protein to complement 1q and complement 1, including influence of hydrogen-ion concentration. Immunol Cell Biol 2002; 78: 558-566.
    • (2002) Immunol Cell Biol , vol.78 , pp. 558-566
    • Rhodes, D.C.J.1
  • 37
    • 0035016941 scopus 로고    scopus 로고
    • Mapping the binding domain of immunoglobulin light chains for Tamm-Horsfall protein
    • Ying WZ, Sanders PW. Mapping the binding domain of immunoglobulin light chains for Tamm-Horsfall protein. Am J Pathol 2001; 158: 1859-1866.
    • (2001) Am J Pathol , vol.158 , pp. 1859-1866
    • Ying, W.Z.1    Sanders, P.W.2
  • 38
    • 0023090684 scopus 로고
    • Uromucoid (Tamm-Horsfall glycoprotein) forms different polymeric arrangements on a filter surface under different physicochemical conditions
    • Wiggins RC. Uromucoid (Tamm-Horsfall glycoprotein) forms different polymeric arrangements on a filter surface under different physicochemical conditions. Clin Chim Acta 1987; 162: 329-340.
    • (1987) Clin Chim Acta , vol.162 , pp. 329-340
    • Wiggins, R.C.1
  • 39
    • 80051949130 scopus 로고    scopus 로고
    • Activation of the bumetanide-sensitive Na+, K+, 2Cl-cotransporter NKCC2 is facilitated by Tamm-Horsfall protein in a chloride-sensitive manner
    • Mutig K, Kahl T, Saritas T et al. Activation of the bumetanide-sensitive Na+,K+,2Cl-cotransporter NKCC2 is facilitated by Tamm-Horsfall protein in a chloride-sensitive manner. J Biol Chem 2011; 286: 30200-30210.
    • (2011) J Biol Chem , vol.286 , pp. 30200-30210
    • Mutig, K.1    Kahl, T.2    Saritas, T.3
  • 40
    • 78751528090 scopus 로고    scopus 로고
    • Tamm-Horsfall glycoprotein interacts with renal outer medullary potassium channel ROMK2 and regulates its function
    • Renigunta A, Renigunta V, Saritas T et al. Tamm-Horsfall glycoprotein interacts with renal outer medullary potassium channel ROMK2 and regulates its function. J Biol Chem 2011; 286: 2224-2235.
    • (2011) J Biol Chem , vol.286 , pp. 2224-2235
    • Renigunta, A.1    Renigunta, V.2    Saritas, T.3
  • 41
    • 0030879756 scopus 로고    scopus 로고
    • An epithelial serine protease activates the amiloride-sensitive sodium channel
    • Vallet V, Chraibi A, Gaeggeler HP et al. An epithelial serine protease activates the amiloride-sensitive sodium channel. Nature 1997; 389: 607-610.
    • (1997) Nature , vol.389 , pp. 607-610
    • Vallet, V.1    Chraibi, A.2    Gaeggeler, H.P.3
  • 42
    • 34250207969 scopus 로고    scopus 로고
    • Epithelial Na+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the gamma-subunit
    • Bruns JB, Carattino MD, Sheng S et al. Epithelial Na+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the gamma-subunit. J Biol Chem 2007; 282: 6153-6160.
    • (2007) J Biol Chem , vol.282 , pp. 6153-6160
    • Bruns, J.B.1    Carattino, M.D.2    Sheng, S.3
  • 43
    • 58149505557 scopus 로고    scopus 로고
    • Plasmin activates epithelial Na+ channels by cleaving the gamma subunit
    • Passero CJ, Mueller GM, Rondon-Berrios H et al. Plasmin activates epithelial Na+ channels by cleaving the gamma subunit. J Biol Chem 2008; 283: 36586-36591.
    • (2008) J Biol Chem , vol.283 , pp. 36586-36591
    • Passero, C.J.1    Mueller, G.M.2    Rondon-Berrios, H.3
  • 44
    • 59949102903 scopus 로고    scopus 로고
    • Plasmin in nephrotic urine activates the epithelial sodium channel
    • Svenningsen P, Bistrup C, Friis UG et al. Plasmin in nephrotic urine activates the epithelial sodium channel. J Am Soc Nephrol 2009; 20: 299-310.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 299-310
    • Svenningsen, P.1    Bistrup, C.2    Friis, U.G.3
  • 45
    • 27144440831 scopus 로고    scopus 로고
    • The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel
    • Chang Q, Hoefs S, van der Kemp AW et al. The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel. Science 2005; 310: 490-493.
    • (2005) Science , vol.310 , pp. 490-493
    • Chang, Q.1    Hoefs, S.2    Van Der Kemp, A.W.3
  • 46
    • 77956642900 scopus 로고    scopus 로고
    • Klotho: A novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule
    • Hu MC, Shi M, Zhang J et al. Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule. FASEB J 2010; 24: 3438-3450.
    • (2010) FASEB J , vol.24 , pp. 3438-3450
    • Hu, M.C.1    Shi, M.2    Zhang, J.3
  • 47
    • 67649834455 scopus 로고    scopus 로고
    • Regulation of renal outer medullary potassium channel and renal K(+) excretion by Klotho
    • Cha SK, Hu MC, Kurosu H et al. Regulation of renal outer medullary potassium channel and renal K(+) excretion by Klotho. Mol Pharmacol 2009; 76: 38-46.
    • (2009) Mol Pharmacol , vol.76 , pp. 38-46
    • Cha, S.K.1    Hu, M.C.2    Kurosu, H.3
  • 48
    • 78449233820 scopus 로고    scopus 로고
    • Down-regulation of intestinal apical calcium entry channel TRPV6 by ubiquitin E3 ligase Nedd4-2
    • Zhang W, Na T, Wu G et al. Down-regulation of intestinal apical calcium entry channel TRPV6 by ubiquitin E3 ligase Nedd4-2. J Biol Chem 2010; 285: 36586-36596.
    • (2010) J Biol Chem , vol.285 , pp. 36586-36596
    • Zhang, W.1    Na, T.2    Wu, G.3
  • 49
    • 1642306406 scopus 로고    scopus 로고
    • Ablation of the Tamm-Horsfall protein gene increases susceptibility of mice to bladder colonization by type 1-fimbriated Escherichia coli
    • Mo L, Zhu XH, Huang HY et al. Ablation of the Tamm-Horsfall protein gene increases susceptibility of mice to bladder colonization by type 1-fimbriated Escherichia coli. Am J Physiol Renal Physiol 2004; 286: F795-F802.
    • (2004) Am J Physiol Renal Physiol , vol.286
    • Mo, L.1    Zhu, X.H.2    Huang, H.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.