A transgenic mouse model for uromodulin-associated kidney diseases shows specific tubulo-interstitial damage, urinary concentrating defect and renal failure

Human Molecular Genetics

Volumn 19, Issue 15, 2010, Pages 2998-3010

  Bernascone, Ilenia ^a   Janas, Sylvie ^b   Ikehata, Masami ^c   Trudu, Matteo ^a   Corbelli, Alessandro ^c   Schaeffer, Céline ^a   Rastaldi, Maria Pia ^c   Devuyst, Olivier ^b   Rampoldi, Luca ^a  

^a DULBECCO TELETHON INSTITUTE   (Italy)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^c FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

TAMM HORSFALL GLYCOPROTEIN; MUCOPROTEIN; MUTANT PROTEIN; TAMM-HORSFALL PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE MODEL; ENDOPLASMIC RETICULUM; FEMALE; INFLAMMATORY INFILTRATE; KIDNEY CONCENTRATING CAPACITY; KIDNEY DISEASE; KIDNEY FAILURE; KIDNEY FIBROSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; TRANSGENIC MOUSE; URINARY EXCRETION; UROMODULIN ASSOCIATED KIDNEY DISEASE; AMINO ACID SEQUENCE; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; DISEASE COURSE; INFLAMMATION; INTRACELLULAR SPACE; KIDNEY TUBULE; METABOLISM; MOLECULAR GENETICS; PATHOLOGY; ULTRASTRUCTURE; URINE; WATER DEPRIVATION;

MUS; MUS MUSCULUS;

AMINO ACID SEQUENCE; ANIMALS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ENDOPLASMIC RETICULUM; INFLAMMATION; INTRACELLULAR SPACE; KIDNEY FAILURE; KIDNEY TUBULES; MICE; MICE, TRANSGENIC; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUCOPROTEINS; MUTANT PROTEINS; PROTEIN TRANSPORT; WATER DEPRIVATION;

EID: 77958171631     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddq205     Document Type: Article

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