-
2
-
-
18844375044
-
Treatment for pancreatic cancer: Current therapy and continued progress
-
Lockhart, A. C.; Rothenberg, M. L.; Berlin, J. D. Treatment for pancreatic cancer: Current therapy and continued progress. Gastroenterology 128:1642-1654; 2005.
-
(2005)
Gastroenterology
, vol.128
, pp. 1642-1654
-
-
Lockhart, A.C.1
Rothenberg, M.L.2
Berlin, J.D.3
-
3
-
-
1642588228
-
Pancreatic cancer
-
Li, D.; Xie, K.; Wolff, R.; Abbruzzese, J. L. Pancreatic cancer. Lancet 363:1049-1057; 2004.
-
(2004)
Lancet
, vol.363
, pp. 1049-1057
-
-
Li, D.1
Xie, K.2
Wolff, R.3
Abbruzzese, J.L.4
-
5
-
-
34548279788
-
Molecular understanding and modern application of traditional medicines: Triumphs and trials
-
Corson, T. W.; Crews, C. M. Molecular understanding and modern application of traditional medicines: Triumphs and trials. Cell 130:769-774; 2007.
-
(2007)
Cell
, vol.130
, pp. 769-774
-
-
Corson, T.W.1
Crews, C.M.2
-
6
-
-
0034909663
-
Triptolide, a novel immunosuppressive and anti-inflammatory agent purified from a Chinese herb Tripterygium wilfordii Hook f
-
Chen, B. J. Triptolide, a novel immunosuppressive and anti-inflammatory agent purified from a Chinese herb Tripterygium wilfordii Hook f. Leuk. Lymphoma 42:253-265; 2001.
-
(2001)
Leuk. Lymphoma
, vol.42
, pp. 253-265
-
-
Chen, B.J.1
-
7
-
-
0042662901
-
Immunosuppressive and anti-inflammatory mechanisms of triptolide, the principal active diterpenoid from the Chinese medicinal herb Tripterygium wilfordii Hook f
-
Qiu, D.; Kao, P. N. Immunosuppressive and anti-inflammatory mechanisms of triptolide, the principal active diterpenoid from the Chinese medicinal herb Tripterygium wilfordii Hook f. Drugs R D 4:1-18; 2003.
-
(2003)
Drugs R D
, vol.4
, pp. 1-18
-
-
Qiu, D.1
Kao, P.N.2
-
8
-
-
0035910420
-
Triptolide and chemotherapy cooperate in tumor cell apoptosis. A role for the p53 pathway
-
Chang, W. T.; Kang, J. J.; Lee, K. Y.; Wei, K.; Anderson, E.; Gotmare, S.; Ross, J. A.; Rosen, G. D. Triptolide and chemotherapy cooperate in tumor cell apoptosis. A role for the p53 pathway. J. Biol. Chem. 276:2221-2227; 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 2221-2227
-
-
Chang, W.T.1
Kang, J.J.2
Lee, K.Y.3
Wei, K.4
Anderson, E.5
Gotmare, S.6
Ross, J.A.7
Rosen, G.D.8
-
9
-
-
0141576565
-
Triptolide inhibits the growth and metastasis of solid tumors
-
Yang, S.; Chen, J.; Guo, Z.; Xu, X. M.; Wang, L.; Pei, X. F.; Yang, J.; Underhill, C. B.; Zhang, L. Triptolide inhibits the growth and metastasis of solid tumors. Mol. Cancer Ther. 2:65-72; 2003.
-
(2003)
Mol. Cancer Ther.
, vol.2
, pp. 65-72
-
-
Yang, S.1
Chen, J.2
Guo, Z.3
Xu, X.M.4
Wang, L.5
Pei, X.F.6
Yang, J.7
Underhill, C.B.8
Zhang, L.9
-
10
-
-
34247605460
-
Suppression of 5-lipoxygenase gene is involved in triptolide-induced apoptosis in pancreatic tumor cell lines
-
Zhou, G. X.; Ding, X. L.; Huang, J. F.; Zhang, H.; Wu, S. B. Suppression of 5-lipoxygenase gene is involved in triptolide-induced apoptosis in pancreatic tumor cell lines. Biochim. Biophys. Acta 1770:1021-1027; 2007.
-
(2007)
Biochim. Biophys. Acta
, vol.1770
, pp. 1021-1027
-
-
Zhou, G.X.1
Ding, X.L.2
Huang, J.F.3
Zhang, H.4
Wu, S.B.5
-
11
-
-
79955831016
-
Triptolide inhibits proliferation and migration of colon cancer cells by inhibition of cell cycle regulators and cytokine receptors
-
Johnson, S. M.; Wang, X.; Evers, B. M. Triptolide inhibits proliferation and migration of colon cancer cells by inhibition of cell cycle regulators and cytokine receptors. J. Surg. Res. 168:197-205; 2011.
-
(2011)
J. Surg. Res.
, vol.168
, pp. 197-205
-
-
Johnson, S.M.1
Wang, X.2
Evers, B.M.3
-
12
-
-
6544295983
-
Overexpression of cyclooxygenase-2 in carcinoma of the pancreas
-
Okami, J.; Yamamoto, H.; Fujiwara, Y.; Tsujie, M.; Kondo, M.; Noura, S.; Oshima, S.; Nagano, H.; Dono, K.; Umeshita, K.; Ishikawa, O.; Sakon, M.; Matsuura, N.; Nakamori, S.; Monden, M. Overexpression of cyclooxygenase-2 in carcinoma of the pancreas. Clin. Cancer Res. 5:2018-2024; 1999.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 2018-2024
-
-
Okami, J.1
Yamamoto, H.2
Fujiwara, Y.3
Tsujie, M.4
Kondo, M.5
Noura, S.6
Oshima, S.7
Nagano, H.8
Dono, K.9
Umeshita, K.10
Ishikawa, O.11
Sakon, M.12
Matsuura, N.13
Nakamori, S.14
Monden, M.15
-
13
-
-
0842345466
-
Overexpression of cyclooxygenase-2 in non-small cell lung cancer
-
Petkova, D. K.; Clelland, C.; Ronan, J.; Pang, L.; Coulson, J. M.; Lewis, S.; Knox, A. J. Overexpression of cyclooxygenase-2 in non-small cell lung cancer. Respir. Med. 98:164-172; 2004.
-
(2004)
Respir. Med.
, vol.98
, pp. 164-172
-
-
Petkova, D.K.1
Clelland, C.2
Ronan, J.3
Pang, L.4
Coulson, J.M.5
Lewis, S.6
Knox, A.J.7
-
14
-
-
2142697273
-
Cyclooxygenase-2: A potential target in breast cancer
-
Wang, D.; Dubois, R. N. Cyclooxygenase-2: A potential target in breast cancer. Semin. Oncol. 31:64-73; 2004.
-
(2004)
Semin. Oncol.
, vol.31
, pp. 64-73
-
-
Wang, D.1
Dubois, R.N.2
-
15
-
-
0036875909
-
Expression of vascular endothelial growth factor (VEGF) and its receptors (Flt-1 and Flk-1) in esophageal squamous cell carcinoma
-
Kato, H.; Yoshikawa, M.; Miyazaki, T.; Nakajima, M.; Fukai, Y.; Masuda, N.; Fukuchi, M.; Manda, R.; Tsukada, K.; Kuwano, H. Expression of vascular endothelial growth factor (VEGF) and its receptors (Flt-1 and Flk-1) in esophageal squamous cell carcinoma. Anticancer Res. 22:3977-3984; 2002.
-
(2002)
Anticancer Res.
, vol.22
, pp. 3977-3984
-
-
Kato, H.1
Yoshikawa, M.2
Miyazaki, T.3
Nakajima, M.4
Fukai, Y.5
Masuda, N.6
Fukuchi, M.7
Manda, R.8
Tsukada, K.9
Kuwano, H.10
-
16
-
-
24344497408
-
Endoglin (CD105) and vascular endothelial growth factor as prognostic markers in esophageal adenocarcinoma
-
Saad, R. S.; El-Gohary, Y.; Memari, E.; Liu, Y. L.; Silverman, J. F. Endoglin (CD105) and vascular endothelial growth factor as prognostic markers in esophageal adenocarcinoma. Hum. Pathol. 36:955-961; 2005.
-
(2005)
Hum. Pathol.
, vol.36
, pp. 955-961
-
-
Saad, R.S.1
El-Gohary, Y.2
Memari, E.3
Liu, Y.L.4
Silverman, J.F.5
-
17
-
-
70349968211
-
Absence of VHL gene alteration and high VEGF expression are associated with tumour aggressiveness and poor survival of renal-cell carcinoma
-
Patard, J. J.; Rioux-Leclercq, N.; Masson, D.; Zerrouki, S.; Jouan, F.; Collet, N.; Dubourg, C.; Lobel, B.; Denis, M.; Fergelot, P. Absence of VHL gene alteration and high VEGF expression are associated with tumour aggressiveness and poor survival of renal-cell carcinoma. Br. J. Cancer 101:1417-1424; 2009.
-
(2009)
Br. J. Cancer
, vol.101
, pp. 1417-1424
-
-
Patard, J.J.1
Rioux-Leclercq, N.2
Masson, D.3
Zerrouki, S.4
Jouan, F.5
Collet, N.6
Dubourg, C.7
Lobel, B.8
Denis, M.9
Fergelot, P.10
-
18
-
-
78349296444
-
Clinicopathologic significance of HIF-1α, CXCR4, and VEGF expression in colon cancer
-
pii: 537531
-
Wu, Y.; Jin, M.; Xu, H.; Shimin, Z.; He, S.; Wang, L.; Zhang, Y. Clinicopathologic significance of HIF-1α, CXCR4, and VEGF expression in colon cancer. Clin. Dev. Immunol. pii: 537531; 2010.
-
(2010)
Clin. Dev. Immunol.
-
-
Wu, Y.1
Jin, M.2
Xu, H.3
Shimin, Z.4
He, S.5
Wang, L.6
Zhang, Y.7
-
19
-
-
0034530889
-
The contributions of cyclooxygenase-2 to tumor angiogenesis
-
Gately, S. The contributions of cyclooxygenase-2 to tumor angiogenesis. Cancer Metastasis Rev. 19:19-27; 2000.
-
(2000)
Cancer Metastasis Rev.
, vol.19
, pp. 19-27
-
-
Gately, S.1
-
20
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2[-Delta Delta C(T)] method
-
Livak, K. J.; Schmittgen, T. D. Analysis of relative gene expression data using real-time quantitative PCR and the 2[-Delta Delta C(T)] method. Methods 25:402-408; 2001.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
21
-
-
45949100633
-
The expression of matrix metalloproteinases-2 and -9 and their tissue inhibitor two in pancreatic ductal and ampullary carcinoma and their relation to angiogenesis and clinicopathological parameters
-
Giannopoulos, G.; Pavlakis, K.; Parasi, A.; Kavatzas, N.; Tiniakos, D.; Karakosta, A.; Tzanakis, N.; Peros, G. The expression of matrix metalloproteinases-2 and -9 and their tissue inhibitor two in pancreatic ductal and ampullary carcinoma and their relation to angiogenesis and clinicopathological parameters. Anticancer Res. 28:1875-1881; 2008.
-
(2008)
Anticancer Res.
, vol.28
, pp. 1875-1881
-
-
Giannopoulos, G.1
Pavlakis, K.2
Parasi, A.3
Kavatzas, N.4
Tiniakos, D.5
Karakosta, A.6
Tzanakis, N.7
Peros, G.8
-
22
-
-
84866735443
-
Triptolide triggers the apoptosis of pancreatic cancer cells via the downregulation of Decoy receptor 3 expression
-
Wang, W.; Li, X.; Sun, W.; Zhang, L.; Zhang, M.; Hong, B.; Lv, G. Triptolide triggers the apoptosis of pancreatic cancer cells via the downregulation of Decoy receptor 3 expression. J. Cancer Res. Clin. Oncol. 138:1597-605; 2012.
-
(2012)
J. Cancer Res. Clin. Oncol.
, vol.138
, pp. 1597-1605
-
-
Wang, W.1
Li, X.2
Sun, W.3
Zhang, L.4
Zhang, M.5
Hong, B.6
Lv, G.7
-
23
-
-
77956418436
-
Novel target genes responsive to the antigrowth activity of triptolide in endometrial and ovarian cancer cells
-
Li, H.; Takai, N.; Yuge, A.; Furukawa, Y.; Tsuno, A.; Tsukamoto, Y.; Kong, S.; Moriyama, M.; Narahara, H. Novel target genes responsive to the antigrowth activity of triptolide in endometrial and ovarian cancer cells. Cancer Lett. 297:198-206; 2010.
-
(2010)
Cancer Lett.
, vol.297
, pp. 198-206
-
-
Li, H.1
Takai, N.2
Yuge, A.3
Furukawa, Y.4
Tsuno, A.5
Tsukamoto, Y.6
Kong, S.7
Moriyama, M.8
Narahara, H.9
-
24
-
-
78650055621
-
MAPKs are not involved in triptolide-induced cell growth inhibition and apoptosis in prostate cancer cell lines with different p53 status
-
Li, W.; Liu, Y.; Li, X. X.; Yu, Y.; Wu, J. J.; Wang, Q.; Huo, H.; Wang, L. M.; Yang, L. MAPKs are not involved in triptolide-induced cell growth inhibition and apoptosis in prostate cancer cell lines with different p53 status. Planta Med. 77:27-31; 2011.
-
(2011)
Planta Med.
, vol.77
, pp. 27-31
-
-
Li, W.1
Liu, Y.2
Li, X.X.3
Yu, Y.4
Wu, J.J.5
Wang, Q.6
Huo, H.7
Wang, L.M.8
Yang, L.9
-
25
-
-
77957861811
-
Triptolide inactivates Akt and induces caspase-dependent death in cervical cancer cells via the mitochondrial pathway
-
Kim, M. J.; Lee, T. H.; Kim, S. H.; Choi, Y. J.; Heo, J.; Kim, Y. H. Triptolide inactivates Akt and induces caspase-dependent death in cervical cancer cells via the mitochondrial pathway. Int. J. Oncol. 37:1177-1185; 2010.
-
(2010)
Int. J. Oncol.
, vol.37
, pp. 1177-1185
-
-
Kim, M.J.1
Lee, T.H.2
Kim, S.H.3
Choi, Y.J.4
Heo, J.5
Kim, Y.H.6
-
26
-
-
80053133737
-
Effect of triptolide on focal adhesion kinase and survival in MCF-7 breast cancer cells
-
Tan, B. J.; Tan, B. H.; Chiu, G. N. Effect of triptolide on focal adhesion kinase and survival in MCF-7 breast cancer cells. Oncol. Rep. 26:1315-1321; 2011.
-
(2011)
Oncol. Rep.
, vol.26
, pp. 1315-1321
-
-
Tan, B.J.1
Tan, B.H.2
Chiu, G.N.3
-
27
-
-
84857995858
-
MRx102, a triptolide derivative, has potent antileukemic activity in vitro and in a murine model of AML
-
Carter, B. Z.; Mak, D. H.; Shi, Y.; Fidler, J. M.; Chen, R.; Ling, X.; Plunkett, W.; Andreeff, M. MRx102, a triptolide derivative, has potent antileukemic activity in vitro and in a murine model of AML. Leukemia 26:443-450; 2012.
-
(2012)
Leukemia
, vol.26
, pp. 443-450
-
-
Carter, B.Z.1
Mak, D.H.2
Shi, Y.3
Fidler, J.M.4
Chen, R.5
Ling, X.6
Plunkett, W.7
Andreeff, M.8
-
28
-
-
70449127470
-
Advance in the antitumor mechanism of triptolide
-
Luo, Y.; Shi, C.; Liao, M. Advance in the antitumor mechanism of triptolide. Zhongguo. Zhong Yao Za Zhi 34:2024-2026; 2009.
-
(2009)
Zhongguo. Zhong Yao Za Zhi
, vol.34
, pp. 2024-2026
-
-
Luo, Y.1
Shi, C.2
Liao, M.3
-
29
-
-
35148831187
-
Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70
-
Phillips, P. A.; Dudeja, V.; McCarroll, J. A.; Borja-Cacho, D.; Dawra, R. K.; Grizzle, W. E.; Vickers, S. M.; Saluja, A. K. Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70. Cancer Res. 67:9407-9416; 2007.
-
(2007)
Cancer Res.
, vol.67
, pp. 9407-9416
-
-
Phillips, P.A.1
Dudeja, V.2
McCarroll, J.A.3
Borja-Cacho, D.4
Dawra, R.K.5
Grizzle, W.E.6
Vickers, S.M.7
Saluja, A.K.8
-
30
-
-
67650552674
-
Triptolide therapy for neuroblastoma decreases cell viability in vitro and inhibits tumor growth in vivo
-
Antonoff, M. B.; Chugh, R.; Borja-Cacho, D.; Dudeja, V.; Clawson, K. A.; Skube, S. J.; Sorenson, B. S.; Saltzman, D. A.; Vickers, S. M.; Saluja, A. K. Triptolide therapy for neuroblastoma decreases cell viability in vitro and inhibits tumor growth in vivo. Surgery 146:282-290; 2009.
-
(2009)
Surgery
, vol.146
, pp. 282-290
-
-
Antonoff, M.B.1
Chugh, R.2
Borja-Cacho, D.3
Dudeja, V.4
Clawson, K.A.5
Skube, S.J.6
Sorenson, B.S.7
Saltzman, D.A.8
Vickers, S.M.9
Saluja, A.K.10
-
31
-
-
84856762756
-
Triptolide augments the effects of 5-lipoxygenase RNA interference in suppressing pancreatic tumor growth in a xenograft mouse model
-
Ding, X.; Zhou, X.; Zhang, H.; Qing, J.; Qiang, H.; Zhou, G. Triptolide augments the effects of 5-lipoxygenase RNA interference in suppressing pancreatic tumor growth in a xenograft mouse model. Cancer Chemother. Pharmacol. 69:253-261; 2012.
-
(2012)
Cancer Chemother. Pharmacol.
, vol.69
, pp. 253-261
-
-
Ding, X.1
Zhou, X.2
Zhang, H.3
Qing, J.4
Qiang, H.5
Zhou, G.6
-
32
-
-
0037307483
-
Cyclooxygenase 2: A molecular target for cancer prevention and treatment
-
Subbaramaiah, K.; Dannenberg, A. J. Cyclooxygenase 2: A molecular target for cancer prevention and treatment. Trends Pharmacol. Sci. 24:96-102; 2003.
-
(2003)
Trends Pharmacol. Sci.
, vol.24
, pp. 96-102
-
-
Subbaramaiah, K.1
Dannenberg, A.J.2
-
33
-
-
78049438246
-
Targeting COX-2 expression by natural compounds: A promising alternative strategy to synthetic COX-2 inhibitors for cancer chemoprevention and therapy
-
Cerella, C.; Sobolewski, C.; Dicato, M.; Diederich, M. Targeting COX-2 expression by natural compounds: A promising alternative strategy to synthetic COX-2 inhibitors for cancer chemoprevention and therapy. Biochem. Pharmacol. 80:1801-1815; 2010.
-
(2010)
Biochem. Pharmacol.
, vol.80
, pp. 1801-1815
-
-
Cerella, C.1
Sobolewski, C.2
Dicato, M.3
Diederich, M.4
-
34
-
-
76749101884
-
Antiangiogenic therapy in lung cancer: Focus on vascular endothelial growth factor pathway
-
Maywood
-
Korpanty, G.; Smyth, E.; Sullivan, L. A.; Brekken, R. A.; Carney, D. N. Antiangiogenic therapy in lung cancer: Focus on vascular endothelial growth factor pathway. Exp. Biol. Med. (Maywood). 235:3-9; 2010.
-
(2010)
Exp. Biol. Med.
, vol.235
, pp. 3-9
-
-
Korpanty, G.1
Smyth, E.2
Sullivan, L.A.3
Brekken, R.A.4
Carney, D.N.5
-
35
-
-
76049110182
-
Antiangiogenic activity of triptolide in anaplastic thyroid carcinoma is mediated by targeting vascular endothelial and tumor cells
-
Zhu, W.; He, S.; Li, Y.; Qiu, P.; Shu, M.; Ou, Y.; Zhou, Y.; Leng, T.; Xie, J.; Zheng, X.; Xu, D.; Su, X.; Yan, G. Antiangiogenic activity of triptolide in anaplastic thyroid carcinoma is mediated by targeting vascular endothelial and tumor cells. Vascul. Pharmacol. 52:46-54; 2010.
-
(2010)
Vascul. Pharmacol.
, vol.52
, pp. 46-54
-
-
Zhu, W.1
He, S.2
Li, Y.3
Qiu, P.4
Shu, M.5
Ou, Y.6
Zhou, Y.7
Leng, T.8
Xie, J.9
Zheng, X.10
Xu, D.11
Su, X.12
Yan, G.13
-
36
-
-
84862830137
-
Synergistic anticancer activity of triptolide combined with cisplatin enhances apoptosis in gastric cancer in vitro and in vivo
-
Li, C. J.; Chu, C. Y.; Huang, L. H.; Wang, M. H.; Sheu, L. F.; Yeh, J. I.; Hsu, H. Y. Synergistic anticancer activity of triptolide combined with cisplatin enhances apoptosis in gastric cancer in vitro and in vivo. Cancer Lett. 319:203-213; 2012.
-
(2012)
Cancer Lett.
, vol.319
, pp. 203-213
-
-
Li, C.J.1
Chu, C.Y.2
Huang, L.H.3
Wang, M.H.4
Sheu, L.F.5
Yeh, J.I.6
Hsu, H.Y.7
-
37
-
-
34249092004
-
Synergistic effect of triptolide combined with 5-fluorouracil on colon carcinoma
-
Tang, X. Y.; Zhu, Y. Q.; Tao, W. H.; Wei, B.; Lin, X. L. Synergistic effect of triptolide combined with 5-fluorouracil on colon carcinoma. Postgrad. Med. J. 83:338-343; 2007.
-
(2007)
Postgrad. Med. J.
, vol.83
, pp. 338-343
-
-
Tang, X.Y.1
Zhu, Y.Q.2
Tao, W.H.3
Wei, B.4
Lin, X.L.5
|