메뉴 건너뛰기




Volumn 30, Issue 2, 2013, Pages 584-588

Cyclin D1 harboring the T286I mutation promotes oncogenic activation in endometrial cancer

Author keywords

Cyclin D1; Endometrial cancer; Mutation; T286I

Indexed keywords

CYCLIN D1; ISOLEUCINE; MUTANT PROTEIN; THREONINE;

EID: 84879662875     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2013.2515     Document Type: Article
Times cited : (15)

References (31)
  • 2
    • 34250202210 scopus 로고    scopus 로고
    • The relationship between histology and outcome in advanced and recurrent endometrial cancer patients participating in first-line chemotherapy trials: A Gynecologic Oncology Group study
    • DOI 10.1016/j.ygyno.2007.04.032, PII S0090825807002995
    • McMeekin DS, Filiaci VL, Thigpen JT, Gallion HH, Fleming GF and Rodgers WH: The relationship between histology and outcome in advanced and recurrent endometrial cancer patients participating in first-line chemotherapy trials: a Gynecologic Oncology Group study. Gynecol Oncol 106: 16-22, 2007. (Pubitemid 46898605)
    • (2007) Gynecologic Oncology , vol.106 , Issue.1 , pp. 16-22
    • McMeekin, D.S.1    Filiaci, V.L.2    Thigpen, J.T.3    Gallion, H.H.4    Fleming, G.F.5    Rodgers, W.H.6
  • 3
    • 28244490997 scopus 로고    scopus 로고
    • High frequency of coexistent mutations of PIK3CA and PTEN genes in endometrial carcinoma
    • DOI 10.1158/0008-5472.CAN-05-2620
    • Oda K, Stokoe D, Taketani Y and McCormick F: High frequency of coexistent mutations of PIK3CA and PTEN genes in endometrial carcinoma. Cancer Res 65: 10669-10673, 2005. (Pubitemid 41713332)
    • (2005) Cancer Research , vol.65 , Issue.23 , pp. 10669-10673
    • Oda, K.1    Stokoe, D.2    Taketani, Y.3    McCormick, F.4
  • 4
    • 54249159640 scopus 로고    scopus 로고
    • PIK3CA cooperates with other phosphatidylinositol 3′-kinase pathway mutations to effect oncogenic transformation
    • Oda K, Okada J, Timmerman L, et al: PIK3CA cooperates with other phosphatidylinositol 3′-kinase pathway mutations to effect oncogenic transformation. Cancer Res 68: 8127-8136, 2008.
    • (2008) Cancer Res , vol.68 , pp. 8127-8136
    • Oda, K.1    Okada, J.2    Timmerman, L.3
  • 5
    • 67649868092 scopus 로고    scopus 로고
    • The oncogenic mutation in the pleckstrin homology domain of AKT1 in endometrial carcinomas
    • Shoji K, Oda K, Nakagawa S, et al: The oncogenic mutation in the pleckstrin homology domain of AKT1 in endometrial carcinomas. Br J Cancer 101: 145-148, 2009.
    • (2009) Br J Cancer , vol.101 , pp. 145-148
    • Shoji, K.1    Oda, K.2    Nakagawa, S.3
  • 6
    • 77950518353 scopus 로고    scopus 로고
    • Genome-wide single-nucleotide polymorphism arrays in endometrial carcinomas associate extensive chromosomal instability with poor prognosis and unveil frequent chromosomal imbalances involved in the PI3-kinase pathway
    • Murayama-Hosokawa S, Oda K, Nakagawa S, et al: Genome-wide single-nucleotide polymorphism arrays in endometrial carcinomas associate extensive chromosomal instability with poor prognosis and unveil frequent chromosomal imbalances involved in the PI3-kinase pathway. Oncogene 29: 1897-1908, 2010.
    • (2010) Oncogene , vol.29 , pp. 1897-1908
    • Murayama-Hosokawa, S.1    Oda, K.2    Nakagawa, S.3
  • 7
    • 84863653671 scopus 로고    scopus 로고
    • Genome-wide single nucleotide polymorphism arrays as a diagnostic tool in patients with synchronous endometrial and ovarian cancer
    • Ikeda Y, Oda K, Nakagawa S, et al: Genome-wide single nucleotide polymorphism arrays as a diagnostic tool in patients with synchronous endometrial and ovarian cancer. Int J Gynecol Cancer 22: 725-731, 2012.
    • (2012) Int J Gynecol Cancer , vol.22 , pp. 725-731
    • Ikeda, Y.1    Oda, K.2    Nakagawa, S.3
  • 8
    • 60749109846 scopus 로고    scopus 로고
    • Cell cycle, CDKs and cancer: A changing paradigm
    • Malumbres M and Barbacid M: Cell cycle, CDKs and cancer: a changing paradigm. Nat Rev Cancer 9: 153-166, 2009.
    • (2009) Nat Rev Cancer , vol.9 , pp. 153-166
    • Malumbres, M.1    Barbacid, M.2
  • 9
    • 0027288908 scopus 로고
    • Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4
    • Kato J, Matsushime H, Hiebert SW, Ewen ME and Sherr CJ: Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4. Genes Dev 7: 331-342, 1993. (Pubitemid 23139228)
    • (1993) Genes and Development , vol.7 , Issue.3 , pp. 331-342
    • Kato, J.1    Matsushime, H.2    Hiebert, S.W.3    Ewen, M.E.4    Sherr, C.J.5
  • 10
    • 0031951182 scopus 로고    scopus 로고
    • Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes
    • Lundberg AS and Weinberg RA: Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes. Mol Cell Biol 18: 753-761, 1998. (Pubitemid 28063408)
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.2 , pp. 753-761
    • Lundberg, A.S.1    Weinberg, R.A.2
  • 11
    • 0033119801 scopus 로고    scopus 로고
    • β-Catenin regulates expression of cyclin D1 in colon carcinoma cells
    • Tetsu O and McCormick F: β-Catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 398: 422-426, 1999.
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 12
    • 0028970609 scopus 로고
    • Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions
    • Albanese C, Johnson J, Watanabe G, et al: Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions. J Biol Chem 270: 23589-23597, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 23589-23597
    • Albanese, C.1    Johnson, J.2    Watanabe, G.3
  • 14
    • 33645118564 scopus 로고    scopus 로고
    • Cyclin D1: Polymorphism, aberrant splicing and cancer risk
    • Knudsen KE, Diehl JA, Haiman CA and Knudsen ES: Cyclin D1: polymorphism, aberrant splicing and cancer risk. Oncogene 25: 1620-1628, 2006.
    • (2006) Oncogene , vol.25 , pp. 1620-1628
    • Knudsen, K.E.1    Diehl, J.A.2    Haiman, C.A.3    Knudsen, E.S.4
  • 16
    • 0242526150 scopus 로고    scopus 로고
    • An Alternatively Spliced Cyclin D1 Isoform, Cyclin D1b, Is a Nuclear Oncogene
    • Lu F, Gladden AB and Diehl JA: An alternatively spliced cyclin D1 isoform, cyclin D1b, is a nuclear oncogene. Cancer Res 63: 7056-7061, 2003. (Pubitemid 37413439)
    • (2003) Cancer Research , vol.63 , Issue.21 , pp. 7056-7061
    • Lu, F.1    Gladden, A.B.2    Diehl, J.A.3
  • 17
    • 18144412328 scopus 로고    scopus 로고
    • Cyclin D1 polymorphism and the risk of endometrial cancer
    • DOI 10.1016/j.ygyno.2005.01.023
    • Kang S, Kim JW, Park NH, Song YS, Kang SB and Lee HP: Cyclin D1 polymorphism and the risk of endometrial cancer. Gynecol Oncol 97: 431-435, 2005. (Pubitemid 40614886)
    • (2005) Gynecologic Oncology , vol.97 , Issue.2 , pp. 431-435
    • Kang, S.1    Kim, J.W.2    Park, N.H.3    Song, Y.S.4    Kang, S.B.5    Lee, H.P.6
  • 21
    • 79954448739 scopus 로고    scopus 로고
    • Multifunctional transcription factor TFII-I is an activator of BRCA1 function
    • Tanikawa M, Wada-Hiraike O, Nakagawa S, et al: Multifunctional transcription factor TFII-I is an activator of BRCA1 function. Br J Cancer 104: 1349-1355, 2011.
    • (2011) Br J Cancer , vol.104 , pp. 1349-1355
    • Tanikawa, M.1    Wada-Hiraike, O.2    Nakagawa, S.3
  • 22
    • 0034671768 scopus 로고    scopus 로고
    • Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation
    • DOI 10.1101/gad.854900
    • Alt JR, Cleveland JL, Hannink M and Diehl JA: Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation. Genes Dev 14: 3102-3114, 2000. (Pubitemid 32015129)
    • (2000) Genes and Development , vol.14 , Issue.24 , pp. 3102-3114
    • Alt, J.R.1    Cleveland, J.L.2    Hannink, M.3    Diehl, J.A.4
  • 23
    • 33244481730 scopus 로고    scopus 로고
    • Expression of constitutively nuclear cyclin D1 in murine lymphocytes induces B-cell lymphoma
    • DOI 10.1038/sj.onc.1209147, PII 1209147
    • Gladden AB, Woolery R, Aggarwal P, Wasik MA and Diehl JA: Expression of constitutively nuclear cyclin D1 in murine lymphocytes induces B-cell lymphoma. Oncogene 25: 998-1007, 2006. (Pubitemid 43277008)
    • (2006) Oncogene , vol.25 , Issue.7 , pp. 998-1007
    • Gladden, A.B.1    Woolery, R.2    Aggarwal, P.3    Wasik, M.A.4    Diehl, J.A.5
  • 24
    • 0029921317 scopus 로고    scopus 로고
    • Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer
    • Hall M and Peters G: Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer. Adv Cancer Res 68: 67-108, 1996. (Pubitemid 26099813)
    • (1996) Advances in Cancer Research , vol.68 , pp. 67-108
    • Hall, M.1    Peters, G.2
  • 25
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr CJ: Cancer cell cycles. Science 274: 1672-1677, 1996.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 27
    • 67650360782 scopus 로고    scopus 로고
    • A cohort study of cyclin D1 expression and prognosis in 602 colon cancer cases
    • Ogino S, Nosho K, Irahara N, et al: A cohort study of cyclin D1 expression and prognosis in 602 colon cancer cases. Clin Cancer Res 15: 4431-4438, 2009.
    • (2009) Clin Cancer Res , vol.15 , pp. 4431-4438
    • Ogino, S.1    Nosho, K.2    Irahara, N.3
  • 28
    • 0028274940 scopus 로고
    • Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene
    • Bodrug SE, Warner BJ, Bath ML, Lindeman GJ, Harris AW and Adams JM: Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene. EMBO J 13: 2124-2130, 1994. (Pubitemid 24139725)
    • (1994) EMBO Journal , vol.13 , Issue.9 , pp. 2124-2130
    • Bodrug, S.E.1    Warner, B.J.2    Bath, M.L.3    Lindeman, G.J.4    Harris, A.W.5    Adams, J.M.6
  • 29
    • 0028049592 scopus 로고
    • Cyclin D1/bcl-1 cooperates with myc genes in the generation of B-cell lymphoma in transgenic mice
    • Lovec H, Grzeschiczek A, Kowalski MB and Moroy T: Cyclin D1/bcl-1 cooperates with myc genes in the generation of B-cell lymphoma in transgenic mice. EMBO J 13: 3487-3495, 1994. (Pubitemid 24246185)
    • (1994) EMBO Journal , vol.13 , Issue.15 , pp. 3487-3495
    • Lovec, H.1    Grzeschiczek, A.2    Kowalski, M.-B.3    Moroy, T.4
  • 30
    • 0027976222 scopus 로고
    • Oncogenic activity of cyclin D1 revealed through cooperation with Ha-ras: Link between cell cycle control and malignant transformation
    • Lovec H, Sewing A, Lucibello FC, Muller R and Moroy T: Oncogenic activity of cyclin D1 revealed through cooperation with Ha-ras: link between cell cycle control and malignant transformation. Oncogene 9: 323-326, 1994. (Pubitemid 24020966)
    • (1994) Oncogene , vol.9 , Issue.1 , pp. 323-326
    • Lovec, H.1    Sewing, A.2    Lucibello, F.C.3    Muller, R.4    Moroy, T.5
  • 31
    • 0029898476 scopus 로고    scopus 로고
    • Oncogenic collaboration of the cyclin D1 (PRAD1, bcl-1) gene with a mutated p53 and an activated ras oncogene in neoplastic transformation
    • Uchimaru K, Endo K, Fujinuma H, Zukerberg L, Arnold A and Motokura T: Oncogenic collaboration of the cyclin D1 (PRAD1, bcl-1) gene with a mutated p53 and an activated ras oncogene in neoplastic transformation. Jpn J Cancer Res 87: 459-465, 1996. (Pubitemid 26182315)
    • (1996) Japanese Journal of Cancer Research , vol.87 , Issue.5 , pp. 459-465
    • Uchimaru, K.1    Endo, K.2    Fujinuma, H.3    Zukerberg, L.4    Arnold, A.5    Motokura, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.