Eleostearic acid induces RIP1-mediated atypical apoptosis in a kinase-independent manner via ERK phosphorylation, ROS generation and mitochondrial dysfunction

Cell Death and Disease

Volumn 4, Issue 6, 2013, Pages

  Obitsu, S ^a   Sakata, K ^a   Teshima, R ^a   Kondo, K ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

AIF; apoptosis; eleostearic acid; mitochondria; reactive oxygen species; RIP1

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCINEURIN; ELEOSTEARIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NECROSTATIN 1; NECROSTATIN 5; PROTEIN SERINE THREONINE KINASE INHIBITOR; REACTIVE OXYGEN METABOLITE; RECEPTOR INTERACTING PROTEIN SERINE 1; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; STEARIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; DEPHOSPHORYLATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION;

EID: 84879653016     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.188     Document Type: Article

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