Design, synthesis and trypanocidal evaluation of novel 1,2,4-triazoles-3- thiones derived from natural piperine

Molecules

Volumn 18, Issue 6, 2013, Pages 6366-6382

  Franklim, Tatiany Nunes ^a   Freire De Lima, Leonardo ^b   De Nazareth Sá Diniz, Julliana ^b   Previato, José Osvaldo ^b   Castro, Rosane Nora ^a   Mendonça Previato, Lucia ^b   De Lima, Marco Edilson Freire ^a  

^a FEDERAL RURAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Antiparasitic drugs; Bioisosterism; Molecular hybridization; Piper nigrum; Trypanosoma cruzi

Indexed keywords

1,2,4 TRIAZOLE; 1,2,4-TRIAZOLE; 1,3 BENZODIOXOLE DERIVATIVE; ALKALOID; AMIDE; ANTITRYPANOSOMAL AGENT; PIPERIDINE DERIVATIVE; PIPERINE; THIOKETONE; TRIAZOLE DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; DRUG EFFECT; DRUG SENSITIVITY; IC 50; SYNTHESIS; TRYPANOSOMA CRUZI; DRUG EFFECTS; IC50;

ALKALOIDS; BENZODIOXOLES; DRUG DESIGN; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; PARASITIC SENSITIVITY TESTS; PIPERIDINES; POLYUNSATURATED ALKAMIDES; THIONES; TRIAZOLES; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

EID: 84879613526     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules18066366     Document Type: Article

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