-
1
-
-
0025731583
-
Structure and function of telomeres
-
Blackburn E.H. Structure and function of telomeres. Nature 1991, 350:569-573.
-
(1991)
Nature
, vol.350
, pp. 569-573
-
-
Blackburn, E.H.1
-
2
-
-
0029563009
-
Telomeres: beginning to understand the end
-
Zakian V.A. Telomeres: beginning to understand the end. Science 1995, 270:1601-1607.
-
(1995)
Science
, vol.270
, pp. 1601-1607
-
-
Zakian, V.A.1
-
3
-
-
0032489012
-
TRF2 protects human telomeres from end-to-end fusions
-
van Steensel B., Smogorzewska A., de Lange T. TRF2 protects human telomeres from end-to-end fusions. Cell 1998, 92:401-413.
-
(1998)
Cell
, vol.92
, pp. 401-413
-
-
van Steensel, B.1
Smogorzewska, A.2
de Lange, T.3
-
4
-
-
0033553536
-
Mammalian telomeres end in a large duplex loop
-
Griffith J.D., Comeau L., Rosenfield S., et al. Mammalian telomeres end in a large duplex loop. Cell 1999, 97:503-514.
-
(1999)
Cell
, vol.97
, pp. 503-514
-
-
Griffith, J.D.1
Comeau, L.2
Rosenfield, S.3
-
5
-
-
41349096243
-
Telomeres, stem cells, and hematology
-
Lansdorp P.M. Telomeres, stem cells, and hematology. Blood 2008, 111:1759-1766.
-
(2008)
Blood
, vol.111
, pp. 1759-1766
-
-
Lansdorp, P.M.1
-
6
-
-
0025115349
-
Structure and variability of human chromosome ends
-
de Lange T., Shiue L., Myers R.M., et al. Structure and variability of human chromosome ends. Mol Cell Biol 1990, 10:518-527.
-
(1990)
Mol Cell Biol
, vol.10
, pp. 518-527
-
-
de Lange, T.1
Shiue, L.2
Myers, R.M.3
-
7
-
-
0034630432
-
Accumulation of short telomeres in human fibroblasts prior to replicative senescence
-
Martens U.M., Chavez E.A., Poon S.S., Schmoor C., Lansdorp P.M. Accumulation of short telomeres in human fibroblasts prior to replicative senescence. Exp Cell Res 2000, 256:291-299.
-
(2000)
Exp Cell Res
, vol.256
, pp. 291-299
-
-
Martens, U.M.1
Chavez, E.A.2
Poon, S.S.3
Schmoor, C.4
Lansdorp, P.M.5
-
8
-
-
0025472467
-
Telomeres, telomerase and senescence
-
Greider C.W. Telomeres, telomerase and senescence. Bioessays 1990, 12:363-369.
-
(1990)
Bioessays
, vol.12
, pp. 363-369
-
-
Greider, C.W.1
-
9
-
-
0025787643
-
Telomere loss: Mitotic clock or genetic time bomb?
-
Harley C.B. Telomere loss: Mitotic clock or genetic time bomb?. Mutat Res 1991, 256:271-282.
-
(1991)
Mutat Res
, vol.256
, pp. 271-282
-
-
Harley, C.B.1
-
10
-
-
0026043444
-
Invivo loss of telomeric repeats with age in humans
-
Lindsey J., McGill N.I., Lindsey L.A., Green D.K., Cooke H.J. Invivo loss of telomeric repeats with age in humans. Mutat Res 1991, 256:45-48.
-
(1991)
Mutat Res
, vol.256
, pp. 45-48
-
-
Lindsey, J.1
McGill, N.I.2
Lindsey, L.A.3
Green, D.K.4
Cooke, H.J.5
-
11
-
-
0026460896
-
Telomere length predicts replicative capacity of human fibroblasts
-
Allsopp R.C., Vaziri H., Patterson C., et al. Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci U S A 1992, 89:10114-10118.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 10114-10118
-
-
Allsopp, R.C.1
Vaziri, H.2
Patterson, C.3
-
12
-
-
0025143252
-
Telomere reduction in human colorectal carcinoma and with ageing
-
Hastie N.D., Dempster M., Dunlop M.G., Thompson A.M., Green D.K., Allshire R.C. Telomere reduction in human colorectal carcinoma and with ageing. Nature 1990, 346:866-868.
-
(1990)
Nature
, vol.346
, pp. 866-868
-
-
Hastie, N.D.1
Dempster, M.2
Dunlop, M.G.3
Thompson, A.M.4
Green, D.K.5
Allshire, R.C.6
-
13
-
-
0027486732
-
Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes
-
Vaziri H., Schachter F., Uchida I., et al. Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes. Am J Hum Genet 1993, 52:661-667.
-
(1993)
Am J Hum Genet
, vol.52
, pp. 661-667
-
-
Vaziri, H.1
Schachter, F.2
Uchida, I.3
-
14
-
-
0343492552
-
Telomere shortening in gastric carcinoma with aging despite telomerase activation
-
Furugori E., Hirayama R., Nakamura K.I., Kammori M., Esaki Y., Takubo K. Telomere shortening in gastric carcinoma with aging despite telomerase activation. J Cancer Res Clin Oncol 2000, 126:481-485.
-
(2000)
J Cancer Res Clin Oncol
, vol.126
, pp. 481-485
-
-
Furugori, E.1
Hirayama, R.2
Nakamura, K.I.3
Kammori, M.4
Esaki, Y.5
Takubo, K.6
-
15
-
-
15244361693
-
Telomere length and hTERT expression in patients with acute myeloid leukemia correlates with chromosomal abnormalities
-
Hartmann U., Brummendorf T.H., Balabanov S., Thiede C., Illme T., Schaich M. Telomere length and hTERT expression in patients with acute myeloid leukemia correlates with chromosomal abnormalities. Haematologica 2005, 90:307-316.
-
(2005)
Haematologica
, vol.90
, pp. 307-316
-
-
Hartmann, U.1
Brummendorf, T.H.2
Balabanov, S.3
Thiede, C.4
Illme, T.5
Schaich, M.6
-
16
-
-
20844444747
-
Telomerase activity and telomere length as prognostic factors of adult T-cell leukemia
-
Kubuki Y., Suzuki M., Sasaki H., et al. Telomerase activity and telomere length as prognostic factors of adult T-cell leukemia. Leuk Lymphoma 2005, 46:393-399.
-
(2005)
Leuk Lymphoma
, vol.46
, pp. 393-399
-
-
Kubuki, Y.1
Suzuki, M.2
Sasaki, H.3
-
17
-
-
13544255726
-
Telomeres and telomerase in paediatric patients with T-cell acute lymphoblastic leukaemia (T-ALL)
-
Kleideiter E., Bangerter U., Schwab M., et al. Telomeres and telomerase in paediatric patients with T-cell acute lymphoblastic leukaemia (T-ALL). Leukemia 2005, 19:296-298.
-
(2005)
Leukemia
, vol.19
, pp. 296-298
-
-
Kleideiter, E.1
Bangerter, U.2
Schwab, M.3
-
18
-
-
0028172626
-
Telomere shortening in leukemic cells is related to their genetic alterations but not replicative capability
-
Ohyashiki K., Ohyashiki J.H., Fujimura T., et al. Telomere shortening in leukemic cells is related to their genetic alterations but not replicative capability. Cancer Genet Cytogenet 1994, 78:64-67.
-
(1994)
Cancer Genet Cytogenet
, vol.78
, pp. 64-67
-
-
Ohyashiki, K.1
Ohyashiki, J.H.2
Fujimura, T.3
-
19
-
-
0032902504
-
Telomere stability is frequently impaired in high-risk groups of patients with myelodysplastic syndromes
-
Ohyashiki J.H., Iwama H., Yahata N., et al. Telomere stability is frequently impaired in high-risk groups of patients with myelodysplastic syndromes. Clin Cancer Res 1999, 5:1155-1160.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1155-1160
-
-
Ohyashiki, J.H.1
Iwama, H.2
Yahata, N.3
-
20
-
-
33947415383
-
Telomere length identifies two different prognostic subgroups among VH-unmutated B-cell chronic lymphocytic leukemia patients
-
Ricca I., Rocci A., Drandi D., et al. Telomere length identifies two different prognostic subgroups among VH-unmutated B-cell chronic lymphocytic leukemia patients. Leukemia 2007, 21:697-705.
-
(2007)
Leukemia
, vol.21
, pp. 697-705
-
-
Ricca, I.1
Rocci, A.2
Drandi, D.3
-
21
-
-
78650053349
-
Telomeres and telomerase in normal and malignant B-cells
-
Lobetti-Bodoni C., Bernocco E., Genuardi E., Boccadoro M., Ladetto M. Telomeres and telomerase in normal and malignant B-cells. Hematol Oncol 2010, 28:157-167.
-
(2010)
Hematol Oncol
, vol.28
, pp. 157-167
-
-
Lobetti-Bodoni, C.1
Bernocco, E.2
Genuardi, E.3
Boccadoro, M.4
Ladetto, M.5
-
22
-
-
79958072402
-
The association of telomere length and cancer: a meta-analysis
-
Wentzensen I.M., Mirabello L., Pfeiffer R.M., Savage S.A. The association of telomere length and cancer: a meta-analysis. Cancer Epidemiol Biomarkers Prev 2011, 20:1238-1250.
-
(2011)
Cancer Epidemiol Biomarkers Prev
, vol.20
, pp. 1238-1250
-
-
Wentzensen, I.M.1
Mirabello, L.2
Pfeiffer, R.M.3
Savage, S.A.4
-
23
-
-
34249001353
-
Short telomeres in aggressive non-Hodgkin's lymphoma as a risk factor in lymphomagenesis
-
Widmann T.A., Herrmann M., Taha N., Konig J., Pfreundschuh M. Short telomeres in aggressive non-Hodgkin's lymphoma as a risk factor in lymphomagenesis. Exp Hematol 2007, 35:939-946.
-
(2007)
Exp Hematol
, vol.35
, pp. 939-946
-
-
Widmann, T.A.1
Herrmann, M.2
Taha, N.3
Konig, J.4
Pfreundschuh, M.5
-
24
-
-
0034235119
-
Telomere length shortening in chronic myelogenous leukemia is associated with reduced time to accelerated phase
-
Boultwood J., Peniket A., Watkins F., et al. Telomere length shortening in chronic myelogenous leukemia is associated with reduced time to accelerated phase. Blood 2000, 96:358-361.
-
(2000)
Blood
, vol.96
, pp. 358-361
-
-
Boultwood, J.1
Peniket, A.2
Watkins, F.3
-
25
-
-
0033973802
-
Telomerase activity and telomere length in acute and chronic leukemia, pre- and post-exvivo culture
-
Engelhardt M., Mackenzie K., Drullinsky P., Silver R.T., Moore M.A. Telomerase activity and telomere length in acute and chronic leukemia, pre- and post-exvivo culture. Cancer Res 2000, 60:610-617.
-
(2000)
Cancer Res
, vol.60
, pp. 610-617
-
-
Engelhardt, M.1
Mackenzie, K.2
Drullinsky, P.3
Silver, R.T.4
Moore, M.A.5
-
26
-
-
0036900213
-
Accelerated telomere length shortening in granulocytes: a diagnostic marker for myeloproliferative diseases
-
Terasaki Y., Okumura H., Ohtake S., Nakao S. Accelerated telomere length shortening in granulocytes: a diagnostic marker for myeloproliferative diseases. Exp Hematol 2002, 30:1399-1404.
-
(2002)
Exp Hematol
, vol.30
, pp. 1399-1404
-
-
Terasaki, Y.1
Okumura, H.2
Ohtake, S.3
Nakao, S.4
-
27
-
-
70350728531
-
Individual telomere lengths in chronic myeloid leukemia
-
Samassekou O., Ntwari A., Hebert J., Yan J. Individual telomere lengths in chronic myeloid leukemia. Neoplasia 2009, 11:1146-1154.
-
(2009)
Neoplasia
, vol.11
, pp. 1146-1154
-
-
Samassekou, O.1
Ntwari, A.2
Hebert, J.3
Yan, J.4
-
28
-
-
70350708508
-
Telomeres and telomerase in chronic myeloid leukaemia: impact for pathogenesis, disease progression and targeted therapy
-
Keller G., Brassat U., Braig M., Heim D., Wege H., Brummendorf T.H. Telomeres and telomerase in chronic myeloid leukaemia: impact for pathogenesis, disease progression and targeted therapy. Hematol Oncol 2009, 27:123-129.
-
(2009)
Hematol Oncol
, vol.27
, pp. 123-129
-
-
Keller, G.1
Brassat, U.2
Braig, M.3
Heim, D.4
Wege, H.5
Brummendorf, T.H.6
-
29
-
-
3242883111
-
Telomere shortening correlates with prognostic score at diagnosis and proceeds rapidly during progression of chronic myeloid leukemia
-
Drummond M., Lennard A., Brummendorf T., Holyoake T. Telomere shortening correlates with prognostic score at diagnosis and proceeds rapidly during progression of chronic myeloid leukemia. Leuk Lymphoma 2004, 45:1775-1781.
-
(2004)
Leuk Lymphoma
, vol.45
, pp. 1775-1781
-
-
Drummond, M.1
Lennard, A.2
Brummendorf, T.3
Holyoake, T.4
-
30
-
-
0037222727
-
Telomere length in peripheral blood granulocytes reflects response to treatment with imatinib in patients with chronic myeloid leukemia
-
Brummendorf T.H., Ersoz I., Hartmann U., et al. Telomere length in peripheral blood granulocytes reflects response to treatment with imatinib in patients with chronic myeloid leukemia. Blood 2003, 101:375-376.
-
(2003)
Blood
, vol.101
, pp. 375-376
-
-
Brummendorf, T.H.1
Ersoz, I.2
Hartmann, U.3
-
31
-
-
0035141317
-
Telomere dynamics and genetic instability in disease progression of chronic myeloid leukemia
-
Ohyashiki K., Iwama H., Tauchi T., et al. Telomere dynamics and genetic instability in disease progression of chronic myeloid leukemia. Leuk Lymphoma 2000, 40:49-56.
-
(2000)
Leuk Lymphoma
, vol.40
, pp. 49-56
-
-
Ohyashiki, K.1
Iwama, H.2
Tauchi, T.3
-
32
-
-
33750091612
-
Telomere length dynamics in normal hematopoiesis and in disease states characterized by increased stem cell turnover
-
Brummendorf T.H., Balabanov S. Telomere length dynamics in normal hematopoiesis and in disease states characterized by increased stem cell turnover. Leukemia 2006, 20:1706-1716.
-
(2006)
Leukemia
, vol.20
, pp. 1706-1716
-
-
Brummendorf, T.H.1
Balabanov, S.2
-
33
-
-
60349111072
-
Telomere length is severely and similarly reduced in JAK2V617F-positive and -negative myeloproliferative neoplasms
-
Bernard L., Belisle C., Mollica L., et al. Telomere length is severely and similarly reduced in JAK2V617F-positive and -negative myeloproliferative neoplasms. Leukemia 2009, 23:287-291.
-
(2009)
Leukemia
, vol.23
, pp. 287-291
-
-
Bernard, L.1
Belisle, C.2
Mollica, L.3
-
34
-
-
14944381162
-
High telomerase activity in granulocytes from clonal polycythemia vera and essential thrombocythemia
-
Ferraris A.M., Mangerini R., Pujic N., et al. High telomerase activity in granulocytes from clonal polycythemia vera and essential thrombocythemia. Blood 2005, 105:2138-2140.
-
(2005)
Blood
, vol.105
, pp. 2138-2140
-
-
Ferraris, A.M.1
Mangerini, R.2
Pujic, N.3
-
35
-
-
79952363751
-
Dynamics of telomere's length and telomerase activity in Philadelphia chromosome negative myeloproliferative neoplasms
-
Spanoudakis E., Bazdiara I., Pantelidou D., et al. Dynamics of telomere's length and telomerase activity in Philadelphia chromosome negative myeloproliferative neoplasms. Leuk Res 2011, 35:459-464.
-
(2011)
Leuk Res
, vol.35
, pp. 459-464
-
-
Spanoudakis, E.1
Bazdiara, I.2
Pantelidou, D.3
-
36
-
-
77949424087
-
Comparative assessment of telomere length before and after hematopoietic SCT: role of grafted cells in determining post-transplant telomere status
-
Ruella M., Rocci A., Ricca I., et al. Comparative assessment of telomere length before and after hematopoietic SCT: role of grafted cells in determining post-transplant telomere status. Bone Marrow Transplant 2010, 45:505-512.
-
(2010)
Bone Marrow Transplant
, vol.45
, pp. 505-512
-
-
Ruella, M.1
Rocci, A.2
Ricca, I.3
-
37
-
-
0032529451
-
Telomere analysis by fluorescence in situ hybridization and flow cytometry
-
Hultdin M., Gronlund E., Norrback K., Eriksson-Lindstrom E., Just T., Roos G. Telomere analysis by fluorescence in situ hybridization and flow cytometry. Nucleic Acids Res 1998, 26:3651-3656.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 3651-3656
-
-
Hultdin, M.1
Gronlund, E.2
Norrback, K.3
Eriksson-Lindstrom, E.4
Just, T.5
Roos, G.6
-
38
-
-
84859195445
-
Methylation of AR locus does not always reflect X chromosome inactivation state
-
Swierczek S.I., Piterkova L., Jelinek J., et al. Methylation of AR locus does not always reflect X chromosome inactivation state. Blood 2012, 119:e100-e109.
-
(2012)
Blood
, vol.119
-
-
Swierczek, S.I.1
Piterkova, L.2
Jelinek, J.3
-
39
-
-
65349193344
-
Skewing of X-inactivation ratios in blood cells of aging women is confirmed by independent methodologies
-
Busque L., Paquette Y., Provost S., et al. Skewing of X-inactivation ratios in blood cells of aging women is confirmed by independent methodologies. Blood 2009, 113:3472-3474.
-
(2009)
Blood
, vol.113
, pp. 3472-3474
-
-
Busque, L.1
Paquette, Y.2
Provost, S.3
-
40
-
-
20144363192
-
Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
-
Baxter E.J., Scott L.M., Campbell P.J., et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 2005, 365:1054-1061.
-
(2005)
Lancet
, vol.365
, pp. 1054-1061
-
-
Baxter, E.J.1
Scott, L.M.2
Campbell, P.J.3
-
41
-
-
42349087790
-
The histone deacetylase inhibitor ITF2357 selectively targets cells bearing mutated JAK2(V617F)
-
Guerini V., Barbui V., Spinelli O., et al. The histone deacetylase inhibitor ITF2357 selectively targets cells bearing mutated JAK2(V617F). Leukemia 2008, 22:740-747.
-
(2008)
Leukemia
, vol.22
, pp. 740-747
-
-
Guerini, V.1
Barbui, V.2
Spinelli, O.3
-
42
-
-
34548128326
-
Prevalence and clinicopathologic correlates of JAK2 exon 12 mutations in JAK2V617F-negative polycythemia vera
-
Pardanani A., Lasho T.L., Finke C., Hanson C.A., Tefferi A. Prevalence and clinicopathologic correlates of JAK2 exon 12 mutations in JAK2V617F-negative polycythemia vera. Leukemia 2007, 21:1960-1963.
-
(2007)
Leukemia
, vol.21
, pp. 1960-1963
-
-
Pardanani, A.1
Lasho, T.L.2
Finke, C.3
Hanson, C.A.4
Tefferi, A.5
-
43
-
-
24944434752
-
Clonal granulocytes in polycythaemia vera and essential thrombocythaemia have shortened telomeres
-
Ferraris A.M., Pujic N., Mangerini R., et al. Clonal granulocytes in polycythaemia vera and essential thrombocythaemia have shortened telomeres. Br J Haematol 2005, 130:391-393.
-
(2005)
Br J Haematol
, vol.130
, pp. 391-393
-
-
Ferraris, A.M.1
Pujic, N.2
Mangerini, R.3
-
44
-
-
79961044558
-
Flow-FISH evaluation of telomere length in Philadelphia-negative myeloproliferative neoplasms
-
Elena C., Rumi E., Portolan M., Della Porta M.G., Pascutto C., Passamonti F. Flow-FISH evaluation of telomere length in Philadelphia-negative myeloproliferative neoplasms. Haematologica 2011, 96:1236-1238.
-
(2011)
Haematologica
, vol.96
, pp. 1236-1238
-
-
Elena, C.1
Rumi, E.2
Portolan, M.3
Della Porta, M.G.4
Pascutto, C.5
Passamonti, F.6
-
45
-
-
79551491928
-
Philadelphia-negative classical myeloproliferative neoplasms: critical concepts and management recommendations from European LeukemiaNet
-
Barbui T., Barosi G., Birgegard G., et al. Philadelphia-negative classical myeloproliferative neoplasms: critical concepts and management recommendations from European LeukemiaNet. J Clin Oncol 2011, 29:761-770.
-
(2011)
J Clin Oncol
, vol.29
, pp. 761-770
-
-
Barbui, T.1
Barosi, G.2
Birgegard, G.3
-
46
-
-
82755192899
-
Role of telomeres and telomerase in cancer
-
Shay J.W., Wright W.E. Role of telomeres and telomerase in cancer. Semin Cancer Biol 2011, 21:349-353.
-
(2011)
Semin Cancer Biol
, vol.21
, pp. 349-353
-
-
Shay, J.W.1
Wright, W.E.2
-
47
-
-
80053945428
-
Treatment of polycythemia vera with hydroxyurea and pipobroman: final results of a randomized trial initiated in 1980
-
Kiladjian J.-J., Chevret S., Dosquet C., Chomienne C., Rain J.-D. Treatment of polycythemia vera with hydroxyurea and pipobroman: final results of a randomized trial initiated in 1980. J Clin Oncol 2011, 29:3907-3913.
-
(2011)
J Clin Oncol
, vol.29
, pp. 3907-3913
-
-
Kiladjian, J.-J.1
Chevret, S.2
Dosquet, C.3
Chomienne, C.4
Rain, J.-D.5
-
48
-
-
79959203501
-
Treatment-related riskfactors for transformation to acute myeloid leukemia and myelodysplastic syndromes in myeloproliferative neoplasms
-
Bjorkholm M., Derolf A.R., Hultcrantz M., et al. Treatment-related riskfactors for transformation to acute myeloid leukemia and myelodysplastic syndromes in myeloproliferative neoplasms. J Clin Oncol 2011, 29:2410-2415.
-
(2011)
J Clin Oncol
, vol.29
, pp. 2410-2415
-
-
Bjorkholm, M.1
Derolf, A.R.2
Hultcrantz, M.3
-
49
-
-
77956696835
-
Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis
-
Verstovsek S., Kantarjian H., Mesa R.A., et al. Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis. NEngl J Med 2010, 363:1117-1127.
-
(2010)
NEngl J Med
, vol.363
, pp. 1117-1127
-
-
Verstovsek, S.1
Kantarjian, H.2
Mesa, R.A.3
-
50
-
-
79952333359
-
Safety and efficacy of TG101348, a selective JAK2 inhibitor, in myelofibrosis
-
Pardanani A., Gotlib J.R., Jamieson C., et al. Safety and efficacy of TG101348, a selective JAK2 inhibitor, in myelofibrosis. J Clin Oncol 2011, 29:789-796.
-
(2011)
J Clin Oncol
, vol.29
, pp. 789-796
-
-
Pardanani, A.1
Gotlib, J.R.2
Jamieson, C.3
-
51
-
-
59949101341
-
Accelerated telomere shortening precedes development of therapy-related myelodysplasia or acute myelogenous leukemia after autologous transplantation for lymphoma
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Chakraborty S., Sun C.L., Francisco L., et al. Accelerated telomere shortening precedes development of therapy-related myelodysplasia or acute myelogenous leukemia after autologous transplantation for lymphoma. J Clin Oncol 2009, 27:791-798.
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(2009)
J Clin Oncol
, vol.27
, pp. 791-798
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Chakraborty, S.1
Sun, C.L.2
Francisco, L.3
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