Vaspin inhibits kallikrein 7 by serpin mechanism

Cellular and Molecular Life Sciences

Volumn 70, Issue 14, 2013, Pages 2569-2583

  Heiker, John T ^a   Klöting, Nora ^a   Kovacs, Peter ^a   Kuettner, E Bartholomeus ^a   Sträter, Norbert ^a   Schultz, Stephan ^a   Kern, Matthias ^a   Stumvoll, Michael ^a   Blüher, Matthias ^a   Beck Sickinger, Annette G ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Crystal structure; Diabetes; Insulin; Kallikrein 7; SerpinA12; Vaspin

Indexed keywords

GLUCOSE; INSULIN; SERINE PROTEINASE INHIBITOR; STRATUM CORNEUM CHYMOTRYPTIC ENZYME; VASPIN;

ADIPOSE TISSUE; ALPHA CHAIN; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BETA CHAIN; CONTROLLED STUDY; CRYSTAL STRUCTURE; CULTURE MEDIUM; FEMALE; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; HYPERINSULINEMIA; IN VITRO STUDY; INHIBITION KINETICS; INSULIN BLOOD LEVEL; INSULIN DEGRADATION; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; MOUSE; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; PATHOPHYSIOLOGY; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN TARGETING;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BLOOD GLUCOSE; CELLS, CULTURED; CRYSTALLOGRAPHY, X-RAY; FEMALE; HUMANS; INSULIN; ISLETS OF LANGERHANS; KALLIKREINS; MALE; MICE; MICE, INBRED C57BL; MICE, OBESE; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SERPINS;

MURINAE; MUS;

EID: 84879604629     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-013-1258-8     Document Type: Article

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