Thyrotropin-Secreting Pituitary Tumors

The Pituitary

Volumn , Issue , 2011, Pages 619-636

  Rouach, Vanessa ^a   Greenman, Yona ^a,b  

^a TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84879602387     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-380926-1.10017-3     Document Type: Chapter

References (151)

1. Jailer J.W., Holub D.A. Remission of Grave's disease following radiotherapy of a pituitary neoplasm. Am J Med 1960, 28:497-500.
2. Buurman H., Saeger W. Subclinical adenomas in postmortem pituitaries: Classification and correlations to clinical data. Eur J Endocrinol 2006, 154:753-758.
3. Davis J.R.E., Farrel W.E., Clayton R.N. Pituitary tumors. Reproduction 2001, 121:363-371.
4. Saeger W., Lüdecke D.K., Buchfelder M., Fahlbusch R., Quabbe H.J., Petersenn S. Pathohistological classification of pituitary tumors: 10 years of experience with the German Pituitary Tumor Registry. Eur J Endocrinol 2007, 156:203-216.
5. Beck-Peccoz P., Brucker-Davis F., Persani L., Smallridge R.C., Weintraub B.D. Thyrotropin-secreting pituitary tumors. Endocr Rev 1996, 17:610-638.
6. Mantovani S., Beck-Peccoz P., Saccomanno K., Spada A., Faglia G., Barbetti F. TSH-secreting pituitary adenomas are monoclonal in origin 1995, Proceedings of the 77th Annual Meeting of the Endocrine Society, Washington DC, p. 412 (abstract P2-485).
7. Ma W., Ikeda H., Watabe N., Kanno M., Yoshimoto T. A plurihormonal TSH-producing pituitary tumor of monoclonal origin in a patient with hypothyroidism. Horm Res 2003, 59:257-261.
8. Dworakowska D., Grossman A. The pathophysiology of pituitary adenomas. Best Prac Res Clin Endocrinol Metab 2009, 23:525-541.
9. Chiamolera M.I., Wondisford F.E. Minireview: Thyrotropin-releasing hormone and the thyroid hormone feedback mechanism. Endocrinology 2009, 150:1091-1096.
10. Persani L. Hypothalamic thyrotropin-releasing hormone and thyrotropin biological activity. Thyroid 1998, 10:941-946.
11. Abel E.D., Ahima R.S., Boers M.E., Elmquist J.K., Wondisford F.E. Critical role for thyroid hormone receptor β2 in the regulation of paraventricular thyrotropin-releasing hormone neurons. J Clin Invest 2001, 107:1017-1023.
12. Horvath E., Kovacs K., Scheithauer B.W. Pituitary hyperplasia. Pituitary 1999, 1:169-180.
13. Vidal S., Horvath E., Kovacs K., Cohen S.M., Lloyd R.V., Scheithauer B.W. Transdifferentiation of somatotrophs to thyrotrophs in the pituitary of patients with protracted primary hypothyroidism. Virchows Arch 2000, 436:43-51.
14. Ghannam N.H., Hammami M.M., Muttair Z., Bakheet S.M. Primary hypothyroidism-associated TSH-secreting pituitary adenoma/hyperplasia presenting as a bleeding nasal mass and extremely elevated TSH level. J Endocrinol Invest 1999, 22:419-423.
15. Tannahill L.A., Visser T.J., McCabe C.J., Kachilele S., Boelaert K., Sheppard M.C., et al. Dysregulation of iodothyronine deiodinase enzyme expression and function in human pituitary tumours. Clin Endocrinol 2002, 56:735-743.
16. Aranda A., Martinez-Iglesias O., Ruiz-Llorente L., Garcia-Carpizo V., Zambrano A. Thyroid receptor: Roles in cancer. Trends Endocrinol Metab 2009, 20:318-324.
17. Wang C.J., Howng S.L., Lin K.H. Expression of thyroid hormone receptors in human pituitary tumor cells. Cancer Lett 1995, 91:79-83.
18. Gittoes N.J., McCabe C.J., Verhaeg J., Sheppard M.C., Franklin J.A. An abnormality of thyroid hormone receptor expression may explain abnormal thyrotropin production in thyrotropin-secreting pituitary tumors. Thyroid 1998, 8:9-14.
19. Ando S., Sarlis N.J., Krishnan J., Feng X., Refetoff S., Zhang M.Q., et al. Aberrant splicing of thyroid hormone receptor in a TSH-secreting pituitary tumor is a mechanism for hormone resistance. Mol Endocrinol 2001, 15:1529-1538.
20. Ando S., Sarlis N.J., Oldfield E.H., Yen P.M. Somatic mutation of TRβ can cause a defect in negative regulation of TSH in a TSH-secreting pituitary tumor. J Clin Endocrinol Metab 2001, 86:5572-5576.
21. Watanabe K., Kameya T., Yamauchi A., et al. Thyrotropin-producing microadenoma associated with pituitary resistance to thyroid hormone. J Clin Endocrinol Metab 1993, 76:1025-1030.
22. Faccenda E., Melmed S., Bevan J.S., Eidne K.A. Structure of the thyrotropin-releasing hormone receptor in human pituitary adenomas. Clin Endocrinol 1996, 44:341-347.
23. Q. Dong, F. Brucker-Davis, B.D. Weintraub, et al., Screening of candidate oncogenes in human thyrotroph tumors: Absence of activating mutations of the G alpha q, G alpha 11, G alpha s, or thyrothropin-releasing hormone receptor genes, J Clin Endocrinol Metab 81 1134-1140.
24. Dunne F.P.M., Feely M.P., Ferriss J.B., Keohane C., Murphy D., Perry I. Hyperthyroidism, inappropriate plasma TSH and pituitary adenoma in three patients, two receiving long-term phenothiazine therapy. Q J Med 1990, 75:345-354.
25. Friedman E., Adams E.F., Hoog A., et al. Normal structural dopamine type 2 receptor gene in prolactin-secreting and other pituitary tumors. J Clin Endocrinol Metab 1994, 78:568-574.
26. Bertherat J., Brue T., Engalbert A., et al. Somatostatin receptors on thyrotropin-secreting pituitary adenomas: Comparison with the inhibitory effects of octreotide upon in vivo and in vitro hormonal secretions. J Clin Endocrinol Metab 1992, 75:540-546.
27. Polak M., Bertherat J., Li J.Y., et al. A human TSH-secreting adenoma: Endocrine, biochemical and morphological studies. Evidence of somatostatin receptors by using quantitative autoradiography. Clinical and biological improvement by SMS 201-995 treatment. Acta Endocrinol (Copenh) 1991, 124:479-486.
28. Horiguchi K., Yamada M., Umezawa R., Satoh T., Hashimoto K., Tosaka M., et al. Somatostatin receptor subtypes mRNA in TSH secreting pituitary adenomas: A case showing a dramatic reduction in tumor size during short octreotide treatment. Endocrine J 2007, 54:371-378.
29. Filopanti M., Ballare E., Lania G., et al. Loss of heterozygosity at the SS receptor type % locus in human GH and TSH-secreting pituitary adenomas. J Endocrinol Invest 2004, 10:937-942.
30. Lania A., Mantovani G., Spada A. Genetic abnormalities of somatostatin receptors in pituitary tumors. Mol Cell Endocrinol 2008, 1-2:180-186.
31. Pellegrini-Bouiller I., Morange-Ramos I., Barlier A., Gunz G., Enjalbert A., Jaquet P. Pit-1 gene expression in human pituitary tumors. Horm Res 1997, 47:251-258.
32. Verges B., Boureille F., Goudet P., et al. Pituitary disease in MEN type 1 (MEN1): Data from the France-Belgium MEN1 multicenter study. J Clin Endocrinol Metab 2002, 87:457-465.
33. Wynne A.G., Gharib I.T., Scheithauer B., Davis D.H., Freeman S.L., Horvath E. Hyperthyroidism due to inappropriate secretion of thyrotropin in 10 patients. Am J Med 1992, 92:15-24.
34. Burgess J.R., Shepherd J.J., Greenaway T.M. Thyrotropinomas in multiple endocrine neoplasia type 1 (MEN-1). Aust NZ J Med 1994, 24:740-741.
35. Taylor T.J., Donlon S.S., Bale A.E., Smallridge R.C., Francis T.B., Christensen R.S., et al. Treatment of a thyrotropinoma with octreotide-LAR in a patient with multiple endocrine neoplasia-1. Thyroid 2000, 10:1001-1007.
36. Gessl A., Freissmuth M., Czech T., et al. Growth hormone-prolactin-thyrotropin-secreting pituitary adenoma in atypical McCune-Albright syndrome with functionally normal Gs alpha protein. J Clin Endocrinol Metab 1994, 79:1128-1134.
37. Tichomirowa M.A., Daly A.F., Beckers A. Familial pituitary adenomas. J Intern Med 2009, 266:5-18.
38. Asteria C., Anagni M., Persani L., et al. Loss of heterozygosity of the MEN1 gene in a large series of TSH-secreting pituitary adenomas. J Endocrinol Invest 2001, 24:796-801.
39. Ezzat S., Horvath E., Kovacs K., Smyth H.S., Singer W., Asa S.L. Basic fibroblast growth factor expression in two prolactin and thyrotropin-producing pituitary adenomas. Endocr Pathol 1995, 6:125-134.
40. Salehi F., Kovacs K., Scheithauer B.W., Lloyd R.V., Cusimano M. Pituitary tumor-transforming gene in endocrine and other neoplasms: A review and update. Endocrine-related Cancer 2008, 15:721-742.
41. Heaney A.P., Horwitz G.A., Wang Z., Singson R., Melmed S. Early involvement of estrogen-induced pituitary tumor transforming gene and fibroblast growth factor expression in prolactinoma pathogenesis. Nat Med 1999, 5:1317-1321.
42. McCabe C.J., Boelaert K., Tannahill L.A., et al. Vascular endothelial growth factor, its receptor KDR/Flk-1, and pituitary transforming gene in pituitary tumors. J Clin Endocrinol Metabol 2002, 87:4238-4244.
43. Abbud R.A., Takumi I., Barker E.M., Ren S.G., Chen D.Y., Wawrowsky K., et al. Early multipotential pituitary focal hyperplasia in the alpha-subunit of glycoprotein hormone-driven pituitary tumor-transforming gene transgenic mice. Mol Endocrinol 2005, 19:1383-1391.
44. Musat M., Korbonits M., Kola B., et al. Enhanced protein kinase B/AKT signaling in pituitary tumours. Endocrine- related Cancer 2005, 12:423-433.
45. Lu C., Willingham M.C., Furuya F., Cheng S. Activation of phospatidylinositol 3-kinase signaling promotes aberrant pituitary growth in a mouse model of thyroid-stimulating hormone-secreting pituitary tumors. Endocrinology 2008, 149:3339-3345.
46. Furumoto H., Ying H., Chandramouli G.V.R., et al. An unliganded thyroid hormone β receptor activates the cyclin D1/cyclin-dependent kinase/retinoblastoma/E2F pathway and induces pituitary tumorigenesis. Mol Cell Biol 2005, 25:124-135.
47. Al-Shraim M., Asa S.L. The 2004 world health organization classification of pituitary tumors: What is new?. Acta Neuropathol 2006, 111:1-7.
48. Osamura R.Y., Kajiya H., Takei M., Egashira N., Tobita M., Takekoshi S., et al. Pathology of the human pituitary adenomas. Histochem Cell Biol 2008, 130:495-507.
49. Malarkey W.B., Kovacs K., O'Dorisio T.M. Response of a GH and TSH-secreting pituitary adenoma to a somatostatin analogue (SMS 201-995): Evidence that GH and TSH coexist in the same cell and secretory granules. Neuroendocrinology 1989, 49:267-274.
50. Kuzuya M., Inoue K., Ishibashi M., et al. Endocrine and immunohistochemical studies on thyrotropin (TSH)-secreting pituitary adenomas: Responses of TSH, α-subunit and growth hormone to hypothalamic releasing hormones and their distribution in adenoma cells. J Clin Endocrinol Metab 1990, 71:1103-1111.
51. Terzolo M., Orlandi F., Basseti M., et al. Hyperthyroidism due to a pituitary adenoma composed of two different cell types, one secreting alpha-subunit alone and another cosecreting alpha-subunit and thyrotropin. J Clin Endocrinol Metab 1991, 72:415-421.
52. Marucci G., Faustini-Fustini M., Righi A., Pasquini E., Frank G., Agati R., et al. Thyrotropin secreting pituitary tumors: Significance of "atypical adenomas" in a series of 10 patients and association with Hashimoto thyroiditis as a cause of delay in diagnosis. J Clin Pathol 2009, 62:455-459.
53. Mixson A.J., Friedman T.C., Katz D.A., et al. Thyrotropin-secreting pituitary carcinoma. J Clin Endocrinol Metab 1993, 76:529-533.
54. Brown R.L., Muzzafar T., Wollman R., Weiss R.E. A pituitary carcinoma secreting TSH and prolactin: A non-secreting adenoma gone awry. Eur J Endocrinol 2006, 154:639-643.
55. Brucker-Davis F., Oldfield E.H., Skarulis M.C., Doppman J.L., Weintraub B.D. Thyrotropin-secreting pituitary tumors: Diagnostic criteria, thyroid hormone sensitivity, and treatment outcome in 25 patients followed at the National Institutes of Health. J Clin Endocrinol Metab 1999, 84:476-486.
56. Kienitz T., Quinkler M., Strasburger C.J., Ventz M. Long-term management in five cases of TSH-secreting pituitary adenomas: A single center study and review of the literature. Eur J Endocrinol 2007, 157:39-46.
57. Teramoto A., Sanno N., Tahara S., Osamura Y.R. Pathological study of thyrotropin-secreting pituitary adenoma: Plurihormonality and medical treatment. Acta Neuropathol 2004, 108:147-153.
58. George J.T., Thow J.C., Matthews B., Pye M.P., Jayagopal V. Atrial fibrillation associated with a thyroid stimulating hormone-secreting adenoma of the pituitary gland leading to a presentation of acute cardiac decompensation: A case report. J Med Case Reports 2008, 28:67.
59. Hsu F.S., Tsai W.S., Chau T., Chen H.H., Chen Y.C., Lin S.H. Thyrotropin-secreting pituitary adenoma presenting as hypokalemic periodic paralysis. Am J Med Sci 2003, 325:48-50.
60. Fischler M.P., Reinhart W.H. TSH-secreting pituitary macroadenoma: Rapid tumor shrinkage and recovery from hyperthyroidism with octreotide. J Endocrinol Invest 1999, 22:64-65.
61. Zuniga S., Mendoza V., Espinoza I.F., Zarate A., Mason M., Mercado M. A plurihormonal TSH-secreting pituitary microadenoma: Report of a case with an atypical clinical presentation and transient response to bromocriptine therapy. Endocr Pathol 1997, 8:81-86.
62. Suntarnlohanakul S., MoSuwan L., Vasiknanont P., Phuenpathom N., Chongchitnant N. TSH secreting pituitary adenoma in children: A case report. J Med Assoc Thai 1990, 73:175-179.
63. Yovos J.G., Falko J.M., O'Dorisio T.M., Malarkey W.B., Cataland S., Capen C.C. Thyrotoxicosis and a thyrotropin-secreting pituitary tumor causing unilateral exophthalmos. J Clin Endocrinol Metab 1981, 53:338-343.
64. Hill S.A., Falko J.M., Wilson C.B., Hunt W.E. Thyrotrophin-producing pituitary adenomas. J Neurosurg 1982, 57:515-519.
65. Clarke M.J., Erickson D., Castro M.R., Atkinson J.L. Thyroid-stimulating hormone pituitary adenomas. J Neurosurg 2008, 109:17-22.
66. Socin H.V., Chanson P., Delemer B., Tabarin A., Rohmer V., Mockel J., et al. The changing spectrum of TSH-secreting pituitary adenomas: Diagnosis and management in 43 patients. Eur J Endocrinol 2003, 148:433-442.
67. Iskandar S.B., Supit E., Jordan R.M., Peiris A.N. Thyrotropin-secreting pituitary tumor and Hashimoto's disease: A novel association. South Med J 2003, 96:933-936.
68. Langlois M.F., Lamarche J.B., Bellabarba D. Long-standing goiter and hypothyroidism: An unusual presentation of a TSH-secreting adenoma. Thyroid 1996, 6:329-335.
69. Losa M., Giovanelli M., Persani L., Mortini P., Faglia G., Beck-Peccoz P. Criteria of cure and follow-up of central hyperthyroidism due to thyrotropin-secreting pituitary adenomas. J Clin Endocrinol Metab 1996, 81:3084-3090.
70. Poggi M., Monti S., Pascucci C., Toscano V. A rare case of follicular thyroid carcinoma in a patient with thyrotropin-secreting pituitary adenoma. Am J Med Sci 2009, 337:462-465.
71. Ohta S., Nishizawa S., Oki Y., Namba H. Coexistence of thyrotropin-producing pituitary adenoma with papillary adenocarcinoma of the thyroid - a case report and surgical strategy. Pituitary 2001, 4:271-274.
72. Calle-Pascual A.L., Yuste E., Martin P., et al. Association of a thyrotropin-secreting pituitary adenoma and a thyroid follicular carcinoma. J Endocrinol Invest 1991, 14:499-502.
73. Gasparoni P., Rubello D., Persani L., Beck-Peccoz P. Unusual association between a thyrotropin-secreting pituitary adenoma and a papillary thyroid carcinoma. Thyroid 1998, 8:181-183.
74. Horn K., Erhardt F., Fahlbusch R., Pickardt C.R., Werder K., Scriba P.C. Recurrent goiter, hyperthyroidism, galactorrhea and amenorrhea due to a thyrotropin and prolactin-producing pituitary tumor. J Clin Endocrinol Metab 1976, 43:137-143.
75. Beck-Peccoz P., Persani L., Mantovani S., Cortelazzi D., Asteria C. Thyrotropin-secreting pituitary adenomas. Metabolism 1996, 45(8 Suppl 1):75-79.
76. Macchia E., Gasperi M., Lombardi M., Morselli L., Pinchera A., Acerbi G., Rossi G., Martino E. Clinical aspects and therapeutic outcome in thyrotropin-secreting pituitary adenomas: A single center experience. J Endocrinol Invest 2009, 32:773-779.
77. Saeger W., Lüdecke D.K. Pituitary adenomas with hyperfunction of TSH. Frequency, histological classification, immunocytochemistry and ultrastructure. Virchows Arch A Pathol Anat Histol 1982, 394:255-267.
78. Roelfsema F., Kok S., Kok P., Pereira A.M., Biermasz N.R., Smit J.W., et al. Pituitary-hormone secretion by thyrotropinomas. Pituitary 2009, 12:200-210.
79. Sanno N., Teramoto A., Matsuno A., Takekoshi S., Osamura R.Y. GH and PRL gene expression by nonradioisotopic in situ hybridization in TSH-secreting pituitary adenomas. J Clin Endocrinol Metab 1995, 80:2518-2522.
80. Wu Y.Y., Chang H.Y., Lin J.D., Chen K.W., Huang Y.Y., Jung S.M. Clinical characteristics of patients with thyrotropin-secreting pituitary adenoma. J Formos Med Assoc 2003, 102:164-171.
81. Ness-Abramof R., Ishay A., Harel G., Sylvetzky N., Baron E., Greenman Y., et al. TSH-secreting pituitary adenomas: Follow-up of 11 cases and review of the literature. Pituitary 2007, 10:307-310.
82. Yoshihara A., Isozaki O., Hizuka N., Nozoe Y., Harada C., Ono M., et al. Expression of type 5 somatostatin receptor in TSH-secreting pituitary adenomas: A possible marker for predicting long-term response to octreotide therapy. Endocr J 2007, 54:133-138.
83. Beck-Peccoz P., Persani L. Variable biological activity of thyroid-stimulating hormone. Eur J Endocrinol 1994, 131:331-340.
84. Beck-Peccoz P., Piscitelli G., Amr S., et al. Endocrine, biochemical, and morphological studies of a pituitary adenoma secreting growth hormone, thyrotropin (TSH), and alpha-subunit: Evidence for secretion of TSH with increased bioactivity. J Clin Endocrinol Metab 1986, 62:704-710.
85. Gesundheit N., Petrick P.A., Nissim M., et al. Thyrotropin-secreting pituitary adenomas: Clinical and biochemical heterogeneity. Ann Intern Med 1989, 111:827-835.
86. Bevan J.S., Burke C.W., Esiri M.M., et al. Studies of two thyrotrophin-secreting pituitary adenomas: Evidence for dopamine receptor deficiency. Clin Endocrinol 1989, 31:59-70.
87. Savastano S., Lombardi G., Merola B., et al. Hyperthyroidism due to a thyroid-stimulating hormone (TSH)-secreting pituitary adenoma associated with functional hyperprolactinemia. Acta Endocrinol 1987, 116:452-458.
88. Filetti S., Rapoport B., Aron D.C., Greenspan E.C., Wilson C.B., Fraser W. TSH and TSH subunit production by human thyrotrophic tumor cells in monolayer culture. Acta Endocrinol 1982, 99:224-231.
89. Magner J.A., Klibanski A., Fein H., et al. Ricin and lentil lectin affinity chromatography reveals oligosaccharide heterogeneity of thyrotropin secreted by 12 human pituitary tumors. Metabolism 1992, 41:1009-1015.
90. Beck-Peccoz P., Persani L., Faglia G. Glycoprotein hormone α-subunit in pituitary adenomas. Trends Endocrinol Metab 1992, 3:41-45.
91. Safer J.D., Colan S.D., Fraser L.M., Wondisford F.E. A pituitary tumor in a patient with thyroid hormone resistance: A diagnostic dilemma. Thyroid 2001, 11:281-291.
92. Beck-Peccoz P., Persani L., Mannavola D., Campi I. Pituitary tumours: TSH-secreting adenomas. Best Pract Res Clin Endocrinol Metab 2009, 23:597-606.
93. Greenman Y., Melmed S. Thyrotropin-secreting pituitary tumors. The Pituitary 1995, 546-558. Blackwell Science, Cambridge. first ed. S. Melmed (Ed.).
94. Bogazzi F., Manetti L., Tomisti L., Rossi G., Cosci C., Sardella C., et al. Thyroid color flow Doppler sonography: An adjunctive tool for differentiating patients with inappropriate thyrotropin (TSH) secretion due to TSH-secreting pituitary adenoma or resistance to thyroid hormone. Thyroid 2006, 16:989-995.
95. Kuhn J.M., Arlot S., Lefebvre H., Caron P., Cortet-Rudelli C., Archambaud F., et al. Evaluation of the treatment of thyrotropin-secreting pituitary adenomas with a slow release formulation of the somatostatin analog lanreotide. J Clin Endocrinol Metab 2000, 85:1487-1491.
96. Chanson P., Weintraub B., Harris A.G. Octreotide therapy for thyroid-stimulating hormone-secreting pituitary adenomas. Ann Intern Med 1993, 119:236-240.
97. van Aken M.O., Pereira A.M., van den Berg G., Romijn J.A., Veldhuis J.D., Roelfsema F. Profound amplification of secretory-burst mass and anomalous regularity of ACTH secretory process in patients with Nelson's syndrome compared with Cushing's disease. Clin Endocrinol (Oxf) 2004, 60:765-772.
98. Groote Veldman R., van den Berg G., Pincus S.M., Frölich M., Veldhuis J.D., Roelfsema F. Increased episodic release and disorderliness of prolactin secretion in both micro- and macroprolactinomas. Eur J Endocrinol 1999, 140:192-200.
99. van den Berg G., Frölich M., Veldhuis J.D., Roelfsema F. Growth hormone secretion in recently operated acromegalic patients. J Clin Endocrinol Metab 1994, 79:1706-1715.
100. Beckers A., Abs R., Mahler C., et al. Thyrotropin-secreting pituitary adenomas: Report of seven cases. J Clin Endocrinol Metab 1991, 72:477-483.
101. Samuels M.H., Wood W.M., Gordon D.E., et al. Clinical and molecular studies of a thyrotropin secreting pituitary adenoma. J Clin Endocrinol Metab 1989, 68:1211-1215.
102. Brabant G., Prank K., Ranft U., et al. Circadian and pulsatile TSH secretion under physiological and pathophysiological conditions. Horm Metab Res 1990, 23(suppl):12-17.
103. Adriaanse R., Brabant G., Endert E., Bemelman F.J., Wiersinga W.M. Pulsatile thyrotropin and prolactin secretion in a patient with a mixed thyrotropin- and prolactin-secreting pituitary adenoma. Eur J Endocrinol 1994, 130:113-120.
104. Roelfsema F., Pereira A.M., Keenan D.M., Veldhuis J.D., Romijn J.A. Thyrotropin secretion by thyrotropinomas is characterized by increased pulse frequency, delayed diurnal rhythm, enhanced basal secretion, spikiness, and disorderliness. J Clin Endocrinol Metab 2008, 93:4052-4057.
105. Sarlis N.J., Gourgiotis L., Koch C.A., Skarulis M.C., Brucker-Davis F., Doppman J.L., et al. MR imaging features of thyrotropin-secreting pituitary adenomas at initial presentation. Am J Roentgenol 2003, 181:577-582.
106. Frank S.I., Gesundheit N., Doppman J.L., et al. Preoperative lateralization of pituitary microadenomas by petrosal sinus sampling: Utility in two patients with non-ACTH-secreting tumors. Am J Med 1989, 87:679-682.
107. Webster J., Peters J.R., John R., et al. Pituitary stone: Two cases of densely calcified thyrotropin-secreting pituitary adenomas. Clin Endocrinol 1994, 40:137-143.
108. Losa M., Magnani P., Mortini P., et al. Indium-111 pentetreotide single-photon emission tomography in patients with TSH-secreting pituitary adenomas: Correlation with the effect of a single administration of octreotide on serum TSL levels. Eur J Nucl Med 1997, 24:728-731.
109. Cooper D.S., Wening B.M. Hyperthyroidism caused by an ectopic TSH-secreting pituitary tumor. Thyroid 1996, 6:337-343.
110. Pasquini E., Faustini-Fustini M., Sciarretta V., Saggese D., Roncaroli F., Serra D., et al. Ectopic TSH-secreting pituitary adenoma of the vomerosphenoidal junction. Eur J Endocrinol 2003, 148:253-257.
111. Verhoeff N.P., Bemelman F.J., Wiersinga W.M., van-Royen E.A. Imaging of dopamine D2 and somatostatin receptors in vivo using single-photon emission tomography in a patient with a TSH/PRL-producing pituitary macroadenoma. Eur J Nucl Med 1993, 20:555-561.
112. deHerder W.W., Reijs A.E., Kwekkeboom D.J., et al. In vivo imaging of pituitary tumors using a radiolabelled dopamine D2 receptor radioligand. Clin Endocrinol 1996, 45:755-767.
113. Refetoff S., Weiss R.E., Usala S.J. The syndromes of resistance to thyroid hormone. Endocr Rev 1993, 14:348-399.
114. Yen P.M. Molecular basis of resistance to thyroid hormone. Trends Endocrinol Metab 2003, 14:327-333.
115. Chatterjee V.K. Resistance to thyroid hormone and peroxisome-proliferator-activated receptor resistance. Biochem Soc Trans 2001, 29:227-231.
116. Yen P.M. Physiological and molecular basis of thyroid hormone action. Physiol Rev 2001, 81:1097-1142.
117. McDermott M.T., Ridgway E.C. Central hyperthyroidism. Endocrinol Metabol Clinics North America 1998, 27:187-203.
118. Beck-Peccoz P., Chatterjee V.K. The variable clinical phenotype in thyroid hormone resistance syndrome. Thyroid 1994, 4:225-232.
119. Brucker-Davis F., Skarulis M.C., Grace M.B., Benichou J., Hauser P., Wiggs E., et al. Genetic and clinical features of 42 kindreds with resistance to thyroid hormone. The National Institutes of Health Prospective Study. Ann Int Med 1995, 123:572-583.
120. Weiss R.E., Refetoff S. Resistance to thyroid hormone. Rev Endocrine Metabolic Disorders 2000, 1:97-108.
121. Machado D.S., Sabet A., Santiago L.A., Sidhaye A.R., Chiamolera M.I., Ortiga-Carvalho T.M., et al. A thyroid hormone receptor mutation that dissociates thyroid hormone regulation of gene expression in vivo. Proc Nat Acad Sci USA 2009, 106:9441-9446.
122. Webb P. Another story of mice and men: The types of RTH. Proc Nat Acad Sci USA 2009, 106:9129-9130.
123. Mannavola D., Persani L., Vannucchi G., Zanardelli M., Fugazzola L., Verga U., et al. Different responses to chronic somatostatin analogues in patients with central hyperthyroidism. Clin Endocrinol (Oxf) 2005, 62:176-181.
124. Beck Peccoz P., Roncoroni R., Mariotti S., et al. Sex hormone-binding globulin measurement in patients with inappropriate secretion of thyrotropin (IST): Evidence against selective pituitary thyroid hormone resistance in nonneoplastic IST. J Clin Endocrinol Metab 1990, 71:19-25.
125. Persani L., Preziati D., Matthews C.H., Sartorio A., Chatterjee V.K., Beck-Peccoz P. Serum levels of carboxyterminal cross-linked telopeptide of type I collagen (ICTP) in the differential diagnosis of the syndrome of inappropriate secretion of TSH. Clin Endocrinol 1997, 47:207-214.
126. Friesema E.C., Grueters A., Biebermann H., Krude H., von Moers A., Reeser M., et al. Association between mutations in a thyroid hormone transporter and severe X-linked psychomotor retardation. Lancet 2004, 364:1435-1437.
127. Dumitrescu A.M., Liao X.H., Abdullah M.S., Lado-Abeal J., Majed F.A., Moeller L.C., et al. Mutations in SECISBP2 result in abnormal thyroid hormone metabolism. Nat Genet 2005, 37:1247-1252.
128. Borst G.C., Eil C., Burman K.D. Euthyroid hyperthyroxinemia. Ann Intern Med 1983, 98:366-378.
129. Glendenning P., Siriwardhana D., Hoad K., Musk A. Thyroxine autoantibody interference is an uncommon cause of inappropriate TSH secretion using the Immulite 2000 assay. Clin Chim Acta 2009, 403:136-138.
130. Tan M.J., Tan F., Hawkins R., Cheah W.K., Mukherjee J.J. A hyperthyroid patient with measurable thyroid-stimulating hormone concentration - a trap for the unwary. Ann Acad Med Singapore 2006, 35:500-503.
131. Cartwright D., O'Shea P., Rajanayagam O., Agostini M., Barker P., Moran C., et al. Familial dysalbuminemic hyperthyroxinemia: A persistent diagnostic challenge. Clin Chem 2009, 55:1044-1046.
132. Gesundheit N. Thyrotropin induced hyperthyroidism. Werner and Ingbar's The Thyroid, a Fundamental and Clinical Text 1991, 682-691. JB Lippincott, Philadelphia. sixth ed. L.E. Braverman, R.D. Utiger (Eds.).
133. Losa M., Mortini P., Franzin A., Barzaghi R., Mandelli C., Giovanelli M. Surgical management of thyrotropin-secreting pituitary adenomas. Pituitary 1999, 2:127-131.
134. Simard M., Mirrell C.J., Pekary A.E., Drexler J., Kovacs K., Hershman J.M. Hormonal control of thyrotropin and growth hormone secretion in a human thyrotrope pituitary adenoma studied in vitro. Acta Endocrinol 1988, 119:283-290.
135. Grisoli F., Leclercg T., Winteler J.P., et al. Thyroid-stimulating hormone pituitary adenomas and hyperthyroidism. Surg Neurol 1986, 25:361-368.
136. McCutcheon I.E., Weintraub B.D., Oldfield E.H. Surgical treatment of thyrotropin-secreting pituitary adenomas. J Neurosurg 1990, 73:674-683.
137. Beck-Peccoz P., Piscitelli G., Amr S., et al. Endocrine, biochemical, and morphological studies of a pituitary adenoma secreting growth hormone, thyrotropin (TSH), and alpha-subunit: Evidence for secretion of TSH with increased bioactivity. J Clin Endocrinol Metab 1986, 62:704-710.
138. Colao A., Pivonello R., Di Somma C., Savastano S., Grasso L.F., Lombardi G. Medical therapy of pituitary adenomas: Effects on tumor shrinkage. Rev Endocr Metab Disord 2009, 10:111-123.
139. Mulinda J.R., Hasinski S., Rose L.I. Successful therapy for a mixed thyrotropin- and prolactin-secreting pituitary macroadenoma with cabergoline. Endocr Pract 1999, 5:76-79.
140. Chanson P., Orgiazzi J., Derome P.J., Bression D., Jedynak C.P., Trouillas J., et al. Paradoxical response of thyrotropin to L-dopa and presence of dopaminergic receptors in a thyrotropin-secreting pituitary adenoma. J Clin Endocrinol Metab 1984, 59:542-546.
141. Mouton F., Faivre-Defrance F., Cortet-Rudelli C., Assaker R., Soto-Ares G., Defoort-Dhellemmes S., et al. TSH-secreting adenoma improved with cabergoline. Ann Endocrinol (Paris) 2008, 69:244-248.
142. Chanson P., Warnet A. Treatment of thyroid-stimulating hormone secreting adenomas with octreotide. Metabolism 1992, 41(suppl.2):62-65.
143. Usui T., Izawa S., Sano T., Tagami T., Nagata D., Shimatsu A., et al. Clinical and molecular features of a TSH-secreting pituitary microadenoma. Pituitary 2005, 8:127-134.
144. Warnet A., Lajeunie E., Gelbert F., et al. Shrinkage of a primary thyrotropin-secreting pituitary adenoma treated with the long-acting somatostatin analogue octreotide (SMS 201-995). Acta Endocrinol 1991, 124:487-491.
145. Colao A., Filippella M., Di Somma C., Manzi S., Rota F., Pivonello R., et al. Somatostatin analogs in treatment of non-growth hormone-secreting pituitary adenomas. Endocrine 2003, 20:279-283.
146. Gancel A., Vuillermet P., Legrand A., Catus F., Thomas F., Kuhn J.M. Effects of a slow-release formulation of the new somatostatin analogue lanreotide in TSH-secreting pituitary adenomas. Clin Endocrinol (Oxf) 1994, 40:421-428.
147. Caron P., Arlot S., Bauters C., Chanson P., Kuhn J.M., Pugeat M., et al. Efficacy of the long-acting octreotide formulation (octreotide-LAR) in patients with thyrotropin-secreting pituitary adenomas. J Clin Endocrinol Metab 2001, 86:2849-2853.
148. Caron P., Gerbeau C., Pradayrol L., Simonetta C., Bayard F. Successful pregnancy in an infertile woman with a thyrotropin-secreting macroadenoma treated with somatostatin analog (octreotide). J Clin Endocrinol Metab 1996, 81:1164-1168.
149. Blackhurst G., Strachan M.W., Collie D., Gregor A., Statham P.F., Seckl J.E. The treatment of a thyrotropin-secreting pituitary macroadenoma with octreotide in twin pregnancy. Clin Endocrinol (Oxf) 2002, 57:401-404.
150. Elston M.S., Conaglen J.V. Clinical and biochemical characteristics of patients with TSH-secreting pituitary adenomas from one New Zealand centre. Intern Med J 2009, 40(3):214-219.
151. Atkinson J.L., Abboud C.F., Lane J.I. Dramatic volume reduction of a large GH/TSH secreting pituitary tumor with short term octreotide therapy. Pituitary 2005, 8:89-91.