Loss of Smu1 function de-represses DNA replication and over-activates ATR-dependent replication checkpoint

Biochemical and Biophysical Research Communications

Volumn 436, Issue 2, 2013, Pages 192-198

  Ren, Laifeng ^a   Liu, Yao ^a   Guo, Liandi ^b   Wang, Haibin ^b   Ma, Lei ^b   Zeng, Ming ^b   Shao, Xin ^c   Yang, Chunlei ^c   Tang, Yaxiong ^d   Wang, Lei ^a   Liu, Cong ^b,c   Li, Mingyuan ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

^c Program for Changjiang Scholars and Innovative Research Team   (China)

^d CHENGDU INSTITUTE OF BIOLOGY   (China)

Author keywords

Checkpoint; DNA damage; DNA replication; Smu1

Indexed keywords

ATR PROTEIN; NUCLEAR PROTEIN; PROTEIN SMU 1; UNCLASSIFIED DRUG;

ARTICLE; DNA DAMAGE; DNA DAMAGE CHECKPOINT; DNA REPLICATION; DNA SYNTHESIS; G2 PHASE CELL CYCLE CHECKPOINT; GENE; GENE EXPRESSION; GENOMICS; GENOTOXICITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REGULATORY MECHANISM; SMU 1 GENE;

ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL SURVIVAL; CHROMATIN; CHROMOSOMAL PROTEINS, NON-HISTONE; DNA REPLICATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINTS; HEK293 CELLS; HUMANS; HYDROXYUREA; MICROSCOPY, FLUORESCENCE; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; ULTRAVIOLET RAYS;

EID: 84879601815     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.05.072     Document Type: Article

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