Analysis of smu-1, a gene that regulates the alternative splicing of unc-52 pre-mRNA in Caenorhabditis elegans

Molecular and Cellular Biology

Volumn 21, Issue 15, 2001, Pages 4985-4995

  Spike, C A ^a   Shaw, J E ^a   Herman, R K ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN; MESSENGER RNA; PROTEIN; RNA BINDING PROTEIN; SMU 1 PROTEIN; UNC 52 PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BASEMENT MEMBRANE; CAENORHABDITIS ELEGANS; EXON; GENE; GENE MUTATION; INTRON; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; RNA SPLICING; SEQUENCE HOMOLOGY;

ALTERNATIVE SPLICING; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL NUCLEUS; CLONING, MOLECULAR; CODON, NONSENSE; EXONS; HELMINTH PROTEINS; MEMBRANE PROTEINS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEAR PROTEINS; PHENOTYPE; PHYSICAL CHROMOSOME MAPPING; PROTEOGLYCANS; RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RIBONUCLEASES; RNA SPLICING; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; SUPPRESSION, GENETIC; TRANS-ACTIVATION (GENETICS); TRANSGENES;

CAENORHABDITIS ELEGANS; HYPODERRIS; INVERTEBRATA; MAMMALIA; NEMATODA;

EID: 0034947727     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.15.4985-4995.2001     Document Type: Article

References (48)

1. Sex in flies: The splice of life
2. The Pfam protein families database
3. Molecular cloning and sequencing of ama-1, the gene encoding the largest subunit of Caenorhabditis elegans RNA polymerase II
4. The maternal gene skn-1 encodes a protein that is distributed unequally in early C. elegans embryos
5. The genetics of Caenorhabditis elegans
6. Genetic control of differentiation of the Caenorhabditis elegans touch receptor neurons
7. Green fluorescent protein as a marker for gene expression
8. SL1 trans-splicing specified by AU-rich synthetic RNA inserted at the 5′ end of Caenorhabditis elegans pre-mRNA
9. Functional overlap between the mec-8 gene and five sym genes in Caenorhabditis elegans
10. The unc-86 gene product couples cell lineage and cell identity in C. elegans
11. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
12. Muscle cell attachment in Caenorhabditis elegans
13. RACE: Rapid amplification of cDNA ends
14. Expression of spliceosome-associated protein 49 is required for early embryogenesis in Caenorhabditis elegans
15. Mutations in the sup-38 gene of Caenorhabditis elegans suppress muscle-attachment defects in unc-52 mutants
16. Splicing regulation in neurons: Tinkering with cell-specific control
17. Alternative splicing of human genes: More the rule than the exception?
18. Genetics
19. Assembly of body wall muscle and muscle cell attachment structures in Caenorhabditis elegans
20. Similarity of the C. elegans developmental timing protein LIN-42 to circadian rhythm proteins
21. Temporal reiteration of a precise gene expression pattern during nematode development
22. Distinct requirements for somatic and germline expression of a generally expressed Caenorhabditis elegans gene
23. Functional characterization of SR and SR-related genes in Caenorhabditis elegans
24. Alternative splicing of pre-mRNA: Developmental consequences and mechanisms of regulation
25. The mec-8 gene of Caenorhabditis elegans affects muscle and sensory neuron function and interacts with three other genes: unc-52, smu-1 and smu-2
26. The mec-8 gene of C. elegans encodes a protein with two RNA recognition motifs and regulates alternative splicing of unc-52 transcripts
27. Muscle development in C. elegans mutants exhibiting retarded sarcomere construction
28. Unproductively spliced ribosomal protein mRNAs are natural targets of mRNA surveillance in C. elegans
29. Cell autonomous expression of perlecan and plasticity of cell shape in embryonic muscle of Caenorhabditis elegans
30. Analysis of a mutator activity necessary for germline transposition and excision of Tc1 transposable elements in Caenorhabditis elegans
31. smg mutants affect the expression of alternatively spliced SR protein mRNAs in Caenorhabditis elegans
32. Complex patterns of alternative splicing mediate the spatial and temporal distribution of perlecan/UNC-52 in Caenorhabditis elegans
33. The ancient regulatory-protein family of WD-repeat proteins
34. Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex
35. Mutant sensory cilia in the nematode Caenorhabditis elegans
36. Caenorhabditis elegans morphogenesis: The role of the cytoskeleton in elongation of the embryo
37. mRNA surveillance by the Caenorhabditis elegans smg genes
38. Products of the unc-52 gene in Caenorhabditis elegans are homologous to the core protein of the mammalian basement membrane heparan sulfate proteoglycan
39. Mutations in the unc-52 gene responsible for body wall muscle defects in adult Caenorhabditis elegans are located in alternatively spliced exons
40. Nuclear organization of pre-mRNA splicing factors
41. Methods
42. Determinants of SR protein specificity
43. The Cln3-Cdc28 kinase complex of S. cerevisiae is regulated by proteolysis and phosphorylation
44. Genes critical for muscle development and function in Caenorhabditis elegans identified through lethal mutations
45. A genetic mapping system in Caenorhabditis elegans based on polymorphic sequence-tagged sites
46. U2AF35 is encoded by an essential gene clustered in an operon with RRM/cyclophilin in Caenorhabditis elegans