Effects of pre-exercise feeding on serum hormone concentrations and biomarkers of myostatin and ubiquitin proteasome pathway activity

European Journal of Nutrition

Volumn 52, Issue 2, 2013, Pages 477-487

  Dalbo, Vincent J ^a   Roberts, Michael D ^b   Hassell, Scott ^c   Kerksick, Chad M ^c  

^a CENTRAL QUEENSLAND UNIVERSITY   (Australia)

^b UNIVERSITY OF MISSOURI   (United States)

^c UNIVERSITY OF OKLAHOMA   (United States)

Author keywords

Cortisol; Hypertrophy; Insulin; Protein; Strength

Indexed keywords

ATROGIN 1; BETA ACTIN; HYDROCORTISONE; INSULIN; MUSCLE RING FINGER 1 PROTEIN; MYOSTATIN; PROTEASOME;

ACTIVIN IIB GENE; ADULT; ARTICLE; BETA ACTIN GENE; CARBOHYDRATE INTAKE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIET SUPPLEMENTATION; DOWN REGULATION; F BOX PROTEIN 32 GENE; FOLLISTATIN LIKE 3 GENE; FORKHEAD BOX O3 GENE; GENE; GENE EXPRESSION; HOUSEKEEPING GENE; HUMAN; HUMAN EXPERIMENT; HYDROCORTISONE BLOOD LEVEL; INSULIN BLOOD LEVEL; MALE; MUSCLE GROWTH; MUSCLE METABOLISM; MUSCLE RING FINGER PROTEIN 1 GENE; MYOSTATIN GENE; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PROTEIN INTAKE; RANDOMIZED CONTROLLED TRIAL; REAL TIME POLYMERASE CHAIN REACTION; RESISTANCE TRAINING; SMAD SPECIFIC E3 UBIQUITIN PROTEIN LIGASE 1 GENE; UPREGULATION;

ACTINS; BIOLOGICAL MARKERS; CROSS-OVER STUDIES; DIETARY CARBOHYDRATES; DIETARY PROTEINS; DOWN-REGULATION; EATING; FOLLISTATIN-RELATED PROTEINS; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; HYDROCORTISONE; INSULIN; MALE; MUSCLE PROTEINS; MUSCLE, SKELETAL; MYOSTATIN; REAL-TIME POLYMERASE CHAIN REACTION; RESISTANCE TRAINING; RNA, MESSENGER; SINGLE-BLIND METHOD; SKP CULLIN F-BOX PROTEIN LIGASES; UBIQUITIN-PROTEIN LIGASES; UP-REGULATION; YOUNG ADULT;

EID: 84879551077     PISSN: 14366207     EISSN: 14366215     Source Type: Journal    
DOI: 10.1007/s00394-012-0349-x     Document Type: Article

References (54)

1. McCroskery S, Thomas M, Maxwell L, et al. (2003) Myostatin negatively regulates satellite cell activation and self-renewal. J Cell Biol 162(6):1135-1147. doi: 10.1083/jcb.200207056
2. Joulia D, Bernardi H, Garandel V, et al. (2003) Mechanisms involved in the inhibition of myoblast proliferation and differentiation by myostatin. Exp Cell Res 286(2):263-275
3. McFarlane C, Hennebry A, Thomas M, et al. (2008) Myostatin signals through Pax7 to regulate satellite cell self-renewal. Exp Cell Res 314(2):317-329. doi: 10.1016/j.yexcr.2007.09.012
4. Costelli P, Muscaritoli M, Bonetto A, et al. (2008) Muscle myostatin signalling is enhanced in experimental cancer cachexia. Eur J Clin Invest 38(7):531-538. doi: 10.1111/j.1365-2362.2008.01970.x
5. Gonzalez-Cadavid NF, Taylor WE, Yarasheski K, et al. (1998) Organization of the human myostatin gene and expression in healthy men and HIV-infected men with muscle wasting. Proc Natl Acad Sci USA 95(25):14938-14943
6. McFarlane C, Plummer E, Thomas M, et al. (2006) Myostatin induces cachexia by activating the ubiquitin proteolytic system through an NF-kappaB-independent, FoxO1-dependent mechanism. J Cell Physiol 209(2):501-514. doi: 10.1002/jcp.20757
7. Amthor H, Otto A, Vulin A, et al. (2009) Muscle hypertrophy driven by myostatin blockade does not require stem/precursor-cell activity. Proc Natl Acad Sci USA 106(18):7479-7484. doi: 10.1073/pnas.0811129106
8. Kraemer WJ, Hakkinen K, Newton RU, et al. (1999) Effects of heavy-resistance training on hormonal response patterns in younger vs. older men. J Appl Physiol 87(3):982-992
9. Bird SP, Tarpenning KM, Marino FE (2006) Effects of liquid carbohydrate/essential amino acid ingestion on acute hormonal response during a single bout of resistance exercise in untrained men. Nutrition 22(4):367-375. doi: 10.1016/j.nut.2005.11.005
10. Allen DL, Cleary AS, Lindsay SF, et al. (2010) Myostatin expression is increased by food deprivation in a muscle-specific manner and contributes to muscle atrophy during prolonged food deprivation in mice. J Appl Physiol 109(3):692-701. doi: 10.1152/japplphysiol.00504.2010
11. Volpi E, Kobayashi H, Sheffield-Moore M, et al. (2003) Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults. Am J Clin Nutr 78(2):250-258
12. Tipton KD, Elliott TA, Cree MG, et al. (2007) Stimulation of net muscle protein synthesis by whey protein ingestion before and after exercise. Am J Physiol Endocrinol Metab 292(1):E71-E76. doi: 10.1152/ajpendo.00166.2006
13. Paddon-Jones D, Sheffield-Moore M, Aarsland A, et al. (2005) Exogenous amino acids stimulate human muscle anabolism without interfering with the response to mixed meal ingestion. Am J Physiol Endocrinol Metab 288(4):E761-E767. doi: 10.1152/ajpendo.00291.2004
14. Long YC, Cheng Z, Copps KD, et al. (2011) Insulin receptor substrates Irs1 and Irs2 coordinate skeletal muscle growth and metabolism via the Akt and AMPK pathways. Mol Cell Biol 31(3):430-441. doi: 10.1128/MCB.00983-10
15. Lecker SH, Goldberg AL, Mitch WE (2006) Protein degradation by the ubiquitin-proteasome pathway in normal and disease states. J Am Soc Nephrol 17(7):1807-1819. doi: 10.1681/ASN.2006010083
16. Andersen LL, Tufekovic G, Zebis MK, et al. (2005) The effect of resistance training combined with timed ingestion of protein on muscle fiber size and muscle strength. Metabolism 54(2):151-156. doi: 10.1016/j.metabol.2004. 07.012
17. Hartman JW, Tang JE, Wilkinson SB, et al. (2007) Consumption of fat-free fluid milk after resistance exercise promotes greater lean mass accretion than does consumption of soy or carbohydrate in young, novice, male weightlifters. Am J Clin Nutr 86(2):373-381
18. Wilkinson SB, Tarnopolsky MA, Macdonald MJ, et al. (2007) Consumption of fluid skim milk promotes greater muscle protein accretion after resistance exercise than does consumption of an isonitrogenous and isoenergetic soy-protein beverage. Am J Clin Nutr 85(4):1031-1040
19. Cribb PJ, Hayes A (2006) Effects of supplement timing and resistance exercise on skeletal muscle hypertrophy. Med Sci Sports Exerc 38(11):1918-1925. doi: 10.1249/01.mss.0000233790.08788.3e
20. Hulmi JJ, Kovanen V, Lisko I, et al. (2008) The effects of whey protein on myostatin and cell cycle-related gene expression responses to a single heavy resistance exercise bout in trained older men. Eur J Appl Physiol 102(2):205-213. doi: 10.1007/s00421-007-0579-4
21. Hulmi JJ, Kovanen V, Selanne H, et al. (2009) Acute and long-term effects of resistance exercise with or without protein ingestion on muscle hypertrophy and gene expression. Amino Acids 37(2):297-308. doi: 10.1007/s00726-008-0150-6
22. Hulmi JJ, Lockwood CM, Stout JR (2010) Effect of protein/essential amino acids and resistance training on skeletal muscle hypertrophy: a case for whey protein. Nutr Metab (Lond) 7:51. doi: 10.1186/1743-7075-7-51
23. Esmarck B, Andersen JL, Olsen S, et al. (2001) Timing of postexercise protein intake is important for muscle hypertrophy with resistance training in elderly humans. J Physiol 535(Pt 1):301-311
24. Joulia-Ekaza D, Cabello G (2007) The myostatin gene: physiology and pharmacological relevance. Curr Opin Pharmacol 7(3):310-315. doi: 10.1016/j.coph.2006.11.011
25. Hill JJ, Davies MV, Pearson AA, et al. (2002) The myostatin propeptide and the follistatin-related gene are inhibitory binding proteins of myostatin in normal serum. J Biol Chem 277(43):40735-40741. doi: 10.1074/jbc.M206379200
26. Ma K, Mallidis C, Bhasin S, et al. (2003) Glucocorticoid-induced skeletal muscle atrophy is associated with upregulation of myostatin gene expression. Am J Physiol Endocrinol Metab 285(2):E363-E371. doi: 10.1152/ajpendo.00487.2002
27. Gilson H, Schakman O, Combaret L, et al. (2007) Myostatin gene deletion prevents glucocorticoid-induced muscle atrophy. Endocrinology 148(1):452-460. doi: 10.1210/en.2006-0539
28. Reid MB (2005) Response of the ubiquitin-proteasome pathway to changes in muscle activity. Am J Physiol Regul Integr Comp Physiol 288(6):R1423-R1431. doi: 10.1152/ajpregu.00545.2004
29. Bodine SC, Latres E, Baumhueter S, et al. (2001) Identification of ubiquitin ligases required for skeletal muscle atrophy. Science 294(5547):1704-1708. doi: 10.1126/science.1065874
30. Sacheck JM, Ohtsuka A, McLary SC, et al. (2004) IGF-I stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1. Am J Physiol Endocrinol Metab 287(4):E591-E601. doi: 10.1152/ajpendo.00073.2004
31. Dalbo VJ, Roberts MD, Hassell SE, et al. (2011) Effects of age on serum hormone concentrations and intramuscular proteolytic signaling before and after a single bout of resistance training. J Strength Cond Res 25(1):1-9. doi: 10.1519/JSC.0b013e3181fc5a68
32. Baechle T, Earle R (2000) Essentials of strength and conditioning, 2nd edn. Human Kinetics, Champaign
33. Dalbo VJ, Roberts MD, Sunderland KL, et al. (2011) Acute loading and aging effects on myostatin pathway biomarkers in human skeletal muscle after three sequential bouts of resistance exercise. J Gerontol A Biol Sci Med Sci. doi: 10.1093/gerona/glr091
34. Mahoney DJ, Carey K, Fu MH, et al. (2004) Real-time RT-PCR analysis of housekeeping genes in human skeletal muscle following acute exercise. Physiol Genomics 18(2):226-231. doi: 10.1152/physiolgenomics.00067.2004
35. Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucl Acids Res 29(9):e45
36. Louis E, Raue U, Yang Y, et al. (2007) Time course of proteolytic, cytokine, and myostatin gene expression after acute exercise in human skeletal muscle. J Appl Physiol 103(5):1744-1751. doi: 10.1152/japplphysiol.00679.2007
37. Costa A, Dalloul H, Hegyesi H, et al. (2007) Impact of repeated bouts of eccentric exercise on myogenic gene expression. Eur J Appl Physiol 101(4):427-436
38. Yang Y, Creer A, Jemiolo B, et al. (2005) Time course of myogenic and metabolic gene expression in response to acute exercise in human skeletal muscle. J Appl Physiol 98(5):1745-1752
39. Hulmi JJ, Tannerstedt J, Selanne H, et al. (2009) Resistance exercise with whey protein ingestion affects mTOR signaling pathway and myostatin in men. J Appl Physiol 106(5):1720-1729. doi: 10.1152/japplphysiol.00087.2009
40. Mascher H, Tannerstedt J, Brink-Elfegoun T, et al. (2008) Repeated resistance exercise training induces different changes in mRNA expression of MAFbx and MuRF-1 in human skeletal muscle. Am J Physiol Endocrinol Metab 294(1):E43-E51. doi: 10.1152/ajpendo.00504.2007
41. Fry AC, Lohnes CA (2010) Acute testosterone and cortisol responses to high power resistance exercise. Fiziol Cheloveka 36(4):102-106
42. McCaulley GO, McBride JM, Cormie P, et al. (2009) Acute hormonal and neuromuscular responses to hypertrophy, strength and power type resistance exercise. Eur J Appl Physiol 105(5):695-704. doi: 10.1007/s00421-008-0951-z
43. Dugue B, Leppanen EA, Teppo AM, et al. (1993) Effects of psychological stress on plasma interleukins-1 beta and 6, C-reactive protein, tumour necrosis factor alpha, anti-diuretic hormone and serum cortisol. Scand J Clin Lab Invest 53(6):555-561
44. Takai N, Yamaguchi M, Aragaki T, et al. (2004) Effect of psychological stress on the salivary cortisol and amylase levels in healthy young adults. Arch Oral Biol 49(12):963-968. doi: 10.1016/j.archoralbio.2004.06.007
45. Borgenvik M, Apro W, Blomstrand E (2012) Intake of branched-chain amino acids influences the levels of MAFbx mRNA and MuRF-1 total protein in resting and exercising human muscle. Am J Physiol Endocrinol Metab 302(5):E510-E521. doi: 10.1152/ajpendo.00353.2011
46. Raue U, Slivka D, Jemiolo B, et al. (2006) Myogenic gene expression at rest and after a bout of resistance exercise in young (18-30 yr) and old (80-89 yr) women. J Appl Physiol 101(1):53-59. doi: 10.1152/japplphysiol.01616.2005
47. Hulmi JJ, Ahtiainen JP, Kaasalainen T, et al. (2007) Postexercise myostatin and activin IIb mRNA levels: effects of strength training. Med Sci Sports Exerc 39(2):289-297. doi: 10.1249/01.mss.0000241650.15006.6e
48. Willoughby DS (2004) Effects of heavy resistance training on myostatin mRNA and protein expression. Med Sci Sports Exerc 36(4):574-582
49. Coffey VG, Shield A, Canny BJ, et al. (2006) Interaction of contractile activity and training history on mRNA abundance in skeletal muscle from trained athletes. Am J Physiol Endocrinol Metab 290(5):E849-E855. doi: 10.1152/ajpendo.00299.2005
50. Cribb PJ, Williams AD, Stathis CG, et al. (2007) Effects of whey isolate, creatine, and resistance training on muscle hypertrophy. Med Sci Sports Exerc 39(2):298-307. doi: 10.1249/01.mss.0000247002.32589.ef
51. Candow DG, Burke NC, Smith-Palmer T, et al. (2006) Effect of whey and soy protein supplementation combined with resistance training in young adults. Int J Sport Nutr Exerc Metab 16(3):233-244
52. Kerksick CM, Rasmussen CJ, Lancaster SL, et al. (2006) The effects of protein and amino acid supplementation on performance and training adaptations during ten weeks of resistance training. J Strength Cond Res 20(3):643-653. doi: 10.1519/R-17695.1
53. Roberts MD, Dalbo VJ, Hassell SE, et al. (2010) Effects of preexercise feeding on markers of satellite cell activation. Med Sci Sports Exerc 42(10):1861-1869. doi: 10.1249/MSS.0b013e3181da8a29
54. Deldicque L, Theisen D, Francaux M (2005) Regulation of mTOR by amino acids and resistance exercise in skeletal muscle. Eur J Appl Physiol 94(1-2):1-10. doi: 10.1007/s00421-004-1255-6