The nitrone spin trap 5,5-dimethyl-1-pyrroline N-oxide affects stress response and fate of lipopolysaccharide-primed RAW 264.7 macrophage cells

Inflammation

Volumn 36, Issue 2, 2013, Pages 346-354

  Zhai, Zili ^a   Gomez Mejiba, Sandra E ^b,c   Ramirez, Dario C ^b,c  

^a UNIVERSITY OF CHICAGO   (United States)

^b CONICET ^*  (Argentina)

^c UNIVERSIDAD NACIONAL DE SAN LUIS   (Argentina)

Author keywords

5,5 dimethyl 1 pyrroline N oxide; apoptosis; ER stress; inflammation; lipopolysaccharide

Indexed keywords

5,5 DIMETHYL 1 PYRROLINE 1 OXIDE; CASPASE 3; CCAAT ENHANCER BINDING PROTEIN; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; NITRONE; PROTEIN 14 3 3; PROTEIN BCL 2;

ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CELL FATE; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; ENZYME INHIBITION; IN VITRO STUDY; MACROPHAGE; PROTEIN EXPRESSION; SPIN TRAPPING;

14-3-3 PROTEINS; ANIMALS; APOPTOSIS; CASPASE 3; CELL LINE; CYCLIC N-OXIDES; ENDOPLASMIC RETICULUM; FREE RADICALS; HEME OXYGENASE-1; INFLAMMATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MEMBRANE PROTEINS; MICE; NITRIC OXIDE SYNTHASE TYPE II; NITROGEN OXIDES; PROTO-ONCOGENE PROTEINS C-BCL-2; SPIN LABELS; SPIN TRAPPING; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTOR CHOP;

EID: 84879499811     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-012-9552-4     Document Type: Article

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