Novel benzimidazole derivatives as expected anticancer agents

Acta Poloniae Pharmaceutica - Drug Research

Volumn 68, Issue 4, 2011, Pages 519-534

  Nofal, Zienab M ^a   Soliman, Elsyed A ^b   Abd El Karim, Somaia S ^a   El Zahar, Magdy I ^a   Srour, Aladdin M ^a   Sethumadhavan, Shalini ^c   Maher, Timothy J ^c  

^a NATIONAL RESEARCH CENTRE   (Egypt)

^b Ain Shams University   (Egypt)

^c MASSACHUSETTS COLLEGE OF PHARMACY AND HEALTH SCIENCES   (United States)

Author keywords

2 Acetylbenzimidazole; Acetohydrazide; Anticancer activity; Chalcones; Glycosides; HEPG2; PC12

Indexed keywords

1 (1H BENZO[D]IMIDAZOL 2 YL) 3 ( 3,4,5 TRIMETHOXYPHENYL)PROP 2 EN 1 ONE; 1 (1H BENZO[D]IMIDAZOL 2 YL) 3 ( 5 METHYLFURAN 2 YL)PROP 2 EN 1 ONE; 2 [ 3 CYANO 4 ( 3,4,5 TRIMETHOXYPHENYL) 6 ( 1 METHYL 1H BENZO[D]IMIDAZOL 2 YL)PYRIDIN 2 YLOXY] N' ACETYLACETOHYDRAZIDE; 2 [ 3 CYANO 4 ( 3,4,5 TRIMETHOXYPHENYL) 6 ( 1 METHYL 1H BENZO[D]IMIDAZOL 2 YL)PYRIDIN 2 YLOXY] N' METHYLTHIOCARBONYL MERCAPTO ACETOHYDRAZIDE; 2 [ 4,5 DIHYDRO 5 ( 3,4,5 TRIMETHOXYPHENYL)ISOXAZOL 3 YL] 1H BENZO[D]IMIDAZOLE; 6 (1H INDOL 3 YL) 4 (1 METHYL 1H BENZO[D]IMIDAZOL 2 YL)PYRIMIDINE 2(1H)THIONE; [2 ( 3 CYANO 4 ( 3,4,5 TRIMETHOXYPHENYL) 6 ( 1 METHYL 1H BENZO[D]IMIDAZOL 2 YL)PYRIDIN 2 YLOXY)ACETYL] 4 METHYLTHIOSEMICARBAZIDE; [2 ( 3 CYANO 4 ( 3,4,5 TRIMETHOXYPHENYL) 6 ( 1 METHYL 1H BENZO[D]IMIDAZOL 2 YL)PYRIDIN 2 YLOXY)ACETYL] 4 PHENYLTHIOSEMICARBAZIDE; ANTINEOPLASTIC AGENT; BENZIMIDAZOLE DERIVATIVE; ETHYL 2 [ 3 CYANO 4 ( 3,4,5 TRIMETHOXYPHENYL) 6 ( 1 METHYL 1H BENZO[D]IMIDAZOL 2 YL)PYRIDIN 2 YLOXY]ACETATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; LIVER CARCINOMA; NONHUMAN; PHEOCHROMOCYTOMA; RAT; STRUCTURE ACTIVITY RELATION;

ADRENAL GLAND NEOPLASMS; ANIMALS; ANTINEOPLASTIC AGENTS; BENZIMIDAZOLES; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MOLECULAR STRUCTURE; PC12 CELLS; PHEOCHROMOCYTOMA; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79959619352     PISSN: 00016837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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