-
1
-
-
70350344966
-
The K+ channels KCa3.1 and KV1.3 as novel targets for asthma therapy
-
Bradding P, Heike W, (2009) The K+ channels KCa3.1 and KV1.3 as novel targets for asthma therapy Br J Pharmacol. 157: 1330-1339.
-
(2009)
Br J Pharmacol
, vol.157
, pp. 1330-1339
-
-
Bradding, P.1
Heike, W.2
-
2
-
-
35848939416
-
KCa3.1 Ca2+-activated K+ channels regulate human airway smooth muscle proliferation
-
Shepherd MC, Duffy SM, Harris T, Cruse G, Schuliga M, et al. (2007) KCa3.1 Ca2+-activated K+ channels regulate human airway smooth muscle proliferation. Am J Respir Cell Mol Biol 37: 525-531.
-
(2007)
Am J Respir Cell Mol Biol
, vol.37
, pp. 525-531
-
-
Shepherd, M.C.1
Duffy, S.M.2
Harris, T.3
Cruse, G.4
Schuliga, M.5
-
4
-
-
77952557868
-
Therapeutic potential of KCa3.1 blockers: Recent advances and promising trends
-
Wulff H, Castle NA, (2010) Therapeutic potential of KCa3.1 blockers: Recent advances and promising trends. Expert Rev Clin Pharmacol 3: 385-396.
-
(2010)
Expert Rev Clin Pharmacol
, vol.3
, pp. 385-396
-
-
Wulff, H.1
Castle, N.A.2
-
5
-
-
3442890222
-
The K+ channel iKCA1 potentiates Ca2+ influx and degranulation in human lung mast cells
-
Duffy M, Berger P, Cruse G, Yang W, Bolton SJ, et al. (2004) The K+ channel iKCA1 potentiates Ca2+ influx and degranulation in human lung mast cells. J Allergy Clin Immunol 114: 66-72.
-
(2004)
J Allergy Clin Immunol
, vol.114
, pp. 66-72
-
-
Duffy, M.1
Berger, P.2
Cruse, G.3
Yang, W.4
Bolton, S.J.5
-
6
-
-
33750019000
-
Functional KCa3.1 K+ channels are required for human lung mast cell migration
-
Cruse G, Duffy SM, Brightling CE, Bradding P, (2006) Functional KCa3.1 K+ channels are required for human lung mast cell migration. Thorax 61: 880-885.
-
(2006)
Thorax
, vol.61
, pp. 880-885
-
-
Cruse, G.1
Duffy, S.M.2
Brightling, C.E.3
Bradding, P.4
-
7
-
-
50949133393
-
Blunted IgE-mediated activation of mast cells in mice lacking the Ca2+-activated K+ channel KCa3.1
-
Shumilina E, Lam RS, Wolbing F, Matzner N, Zemtsova IM, et al. (2008) Blunted IgE-mediated activation of mast cells in mice lacking the Ca2+-activated K+ channel KCa3.1. J Immunol 180: 8040-8047.
-
(2008)
J Immunol
, vol.180
, pp. 8040-8047
-
-
Shumilina, E.1
Lam, R.S.2
Wolbing, F.3
Matzner, N.4
Zemtsova, I.M.5
-
8
-
-
0037336914
-
Induction of allergic inflammation in the lungs of sensitized sheep after local challenge with house dust mite
-
Bischof RJ, Snibson K, Shaw R, Meeusen ENT, (2003) Induction of allergic inflammation in the lungs of sensitized sheep after local challenge with house dust mite. Clin Exp Allergy 33: 367-375.
-
(2003)
Clin Exp Allergy
, vol.33
, pp. 367-375
-
-
Bischof, R.J.1
Snibson, K.2
Shaw, R.3
Meeusen, E.N.T.4
-
9
-
-
33750318921
-
Chronic airway disease: Deteriorating pulmonary function in sheep associated with repeated challenges of house dust mite
-
Koumoundouros E, Bischof RJ, Meeusen EN, Mareels IMY, Snibson KJ, (2006) Chronic airway disease: Deteriorating pulmonary function in sheep associated with repeated challenges of house dust mite. Exp Lung Res 32: 321-330.
-
(2006)
Exp Lung Res
, vol.32
, pp. 321-330
-
-
Koumoundouros, E.1
Bischof, R.J.2
Meeusen, E.N.3
Mareels, I.M.Y.4
Snibson, K.J.5
-
10
-
-
14844355588
-
Airway remodelling and inflammation in sheep lungs after chronic airway challenge with house dust mite
-
Snibson KJ, Bischof RJ, Slocombe RF, Meeusen EN, (2005) Airway remodelling and inflammation in sheep lungs after chronic airway challenge with house dust mite. Clin Exp Allergy 35: 146-152.
-
(2005)
Clin Exp Allergy
, vol.35
, pp. 146-152
-
-
Snibson, K.J.1
Bischof, R.J.2
Slocombe, R.F.3
Meeusen, E.N.4
-
11
-
-
84860993040
-
Increased mast cell density and airway responses to allergic and non-allergic stimuli in a sheep model of chronic asthma
-
Van der Velden J, Barker D, Barcham G, Koumoundouros E, Snibson K, (2012) Increased mast cell density and airway responses to allergic and non-allergic stimuli in a sheep model of chronic asthma. PLoS ONE 7: e37161.
-
(2012)
PLoS ONE
, vol.7
-
-
Van der Velden, J.1
Barker, D.2
Barcham, G.3
Koumoundouros, E.4
Snibson, K.5
-
12
-
-
84862906151
-
Increased vascular density is a persistent feature of airway remodeling in a sheep model of chronic asthm
-
Van der Velden J, Barker D, Barcham G, Koumoundouros E, Snibson K, (2012) Increased vascular density is a persistent feature of airway remodeling in a sheep model of chronic asthm. Exp Lung Res 38: 307-315.
-
(2012)
Exp Lung Res
, vol.38
, pp. 307-315
-
-
Van der Velden, J.1
Barker, D.2
Barcham, G.3
Koumoundouros, E.4
Snibson, K.5
-
13
-
-
0035887787
-
Resting and activation-dependent ion channels in human mast cells
-
Duffy SM, Lawley WJ, Conley EC, Bradding P, (2001) Resting and activation-dependent ion channels in human mast cells. J Immunol 167: 4261-4270.
-
(2001)
J Immunol
, vol.167
, pp. 4261-4270
-
-
Duffy, S.M.1
Lawley, W.J.2
Conley, E.C.3
Bradding, P.4
-
14
-
-
0029614666
-
Role of tryptase in immediate cutaneous responses in allergic sheep
-
Molinari JF, Moore WR, Clark J, Tanaka R, Butterfield JH, et al. (1995) Role of tryptase in immediate cutaneous responses in allergic sheep. J Appl Physiol 79: 1966-1970.
-
(1995)
J Appl Physiol
, vol.79
, pp. 1966-1970
-
-
Molinari, J.F.1
Moore, W.R.2
Clark, J.3
Tanaka, R.4
Butterfield, J.H.5
-
15
-
-
82555164971
-
Functional KCa3.1 K+ channels are required for human fibrocyte migration
-
Cruse G, Singh SR, Duffy SM, Doe C, Saunders R, et al. (2011) Functional KCa3.1 K+ channels are required for human fibrocyte migration. J Allergy Clin Immunol 128: 1303-1309 e1302.
-
(2011)
J Allergy Clin Immunol
, vol.128
-
-
Cruse, G.1
Singh, S.R.2
Duffy, S.M.3
Doe, C.4
Saunders, R.5
-
16
-
-
0037438409
-
Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway
-
Flood-Page PT, Menzies-Gow AN, Kay AB, Robinson DS, (2003) Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway. Am J Respir Crit Care Med 167: 199-204.
-
(2003)
Am J Respir Crit Care Med
, vol.167
, pp. 199-204
-
-
Flood-Page, P.T.1
Menzies-Gow, A.N.2
Kay, A.B.3
Robinson, D.S.4
-
17
-
-
61849086181
-
Mepolizumab and exacerbations of refractory eosinophilic asthma
-
Haldar P, Brightling CE, Hargadon B, Gupta S, Monteiro W, et al. (2009) Mepolizumab and exacerbations of refractory eosinophilic asthma. New Engl J Med 360: 973-984.
-
(2009)
New Engl J Med
, vol.360
, pp. 973-984
-
-
Haldar, P.1
Brightling, C.E.2
Hargadon, B.3
Gupta, S.4
Monteiro, W.5
-
18
-
-
0037202790
-
Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial
-
Green RH, Brightling CE, McKenna S, Hargadon B, Parker D, et al. (2002) Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. Lancet 360: 1715-1721.
-
(2002)
Lancet
, vol.360
, pp. 1715-1721
-
-
Green, R.H.1
Brightling, C.E.2
McKenna, S.3
Hargadon, B.4
Parker, D.5
-
19
-
-
0028913347
-
Angiogenesis: role of calcium-mediated signal transduction
-
Kohn EC, Alessandro R, Spoonster J, Wersto RP, Liotta LA, (1995) Angiogenesis: role of calcium-mediated signal transduction. Proceedings of the National Academy of Sciences 92: 1307-1311.
-
(1995)
Proceedings of the National Academy of Sciences
, vol.92
, pp. 1307-1311
-
-
Kohn, E.C.1
Alessandro, R.2
Spoonster, J.3
Wersto, R.P.4
Liotta, L.A.5
-
20
-
-
34948842015
-
Vascular remodeling is a feature of asthma and nonasthmatic eosinophilic bronchitis
-
Siddiqui S, Sutcliffe A, Shikotra A, Woodman L, Doe C, et al. (2007) Vascular remodeling is a feature of asthma and nonasthmatic eosinophilic bronchitis. J Allergy Clin Immunol 120: 813-819.
-
(2007)
J Allergy Clin Immunol
, vol.120
, pp. 813-819
-
-
Siddiqui, S.1
Sutcliffe, A.2
Shikotra, A.3
Woodman, L.4
Doe, C.5
-
21
-
-
16244383259
-
Selective blockade of the intermediate-conductance Ca2+-activated K+ channel suppresses proliferation of microvascular and macrovascular endothelial cells and angiogenesis in vivo
-
Grgic I, Eichler I, Heinau P, Si H, Brakemeier S, et al. (2005) Selective blockade of the intermediate-conductance Ca2+-activated K+ channel suppresses proliferation of microvascular and macrovascular endothelial cells and angiogenesis in vivo. Arterioscler Thromb Vasc Biol 25: 704-709.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 704-709
-
-
Grgic, I.1
Eichler, I.2
Heinau, P.3
Si, H.4
Brakemeier, S.5
-
22
-
-
0032873676
-
Inhibition of T cell proliferation by selective block of Ca2+-activated K+ channels
-
Jensen BS, Ødum N, Jørgensen NK, Christophersen P, Olesen S-P, (1999) Inhibition of T cell proliferation by selective block of Ca2+-activated K+ channels. Proc Natl Acad Sci USA 96: 10917-10921.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 10917-10921
-
-
Jensen, B.S.1
Ødum, N.2
Jørgensen, N.K.3
Christophersen, P.4
Olesen, S.-P.5
-
23
-
-
0038481183
-
The voltage-gated Kv1.3 K+ channel in effector memory T cells as new target for MS
-
Wulff H, Calabresi PA, Allie R, Yun S, Pennington M, et al. (2003) The voltage-gated Kv1.3 K+ channel in effector memory T cells as new target for MS. J Clin Invest 111: 1703-1713.
-
(2003)
J Clin Invest
, vol.111
, pp. 1703-1713
-
-
Wulff, H.1
Calabresi, P.A.2
Allie, R.3
Yun, S.4
Pennington, M.5
-
24
-
-
0037338904
-
The role of T lymphocytes in the pathogenesis of asthma
-
Larche M, Robinson DS, Kay AB, (2003) The role of T lymphocytes in the pathogenesis of asthma. J Allergy Clin Immunol 111: 450-463.
-
(2003)
J Allergy Clin Immunol
, vol.111
, pp. 450-463
-
-
Larche, M.1
Robinson, D.S.2
Kay, A.B.3
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