Fatty acids and other risk factors for sudden cardiac death in patients starting hemodialysis

American Journal of Nephrology

Volumn 38, Issue 1, 2013, Pages 12-18

  Friedman, Allon N ^a   Yu, Zhangsheng ^b   Denski, Cheryl ^b   Tamez, Hector ^c   Wenger, Julia ^c   Thadhani, Ravi ^c   Li, Yong ^d   Watkins, Bruce ^d  

^a Nephrology Division   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Cardiovascular disease; Fatty acids; Hemodialysis; Incident; Nutrition; Omega 3; Risk factors; Sudden cardiac death

Indexed keywords

ALBUMIN; ALKALINE PHOSPHATASE; CALCIUM; CHOLESTEROL; CREATININE; DOCOSAPENTAENOIC ACID; FATTY ACID; FERRITIN; GLUCOSE; HEMOGLOBIN; LONG CHAIN FATTY ACID; MONOUNSATURATED FATTY ACID; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; PARATHYROID HORMONE; PHOSPHOLIPID; PHOSPHORUS; POLYUNSATURATED FATTY ACID; POTASSIUM; SATURATED FATTY ACID;

AGED; ALBUMIN BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ARTICLE; CALCIUM BLOOD LEVEL; CAUSE OF DEATH; CHOLESTEROL BLOOD LEVEL; CREATININE BLOOD LEVEL; DIASTOLIC BLOOD PRESSURE; ELASTIC TISSUE; FATTY ACID BLOOD LEVEL; FEMALE; FERRITIN BLOOD LEVEL; GLUCOSE BLOOD LEVEL; HEMODIALYSIS; HEMODIALYSIS PATIENT; HEMOGLOBIN BLOOD LEVEL; HUMAN; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; PARATHYROID HORMONE BLOOD LEVEL; PHOSPHATE BLOOD LEVEL; PHOSPHOLIPID BLOOD LEVEL; POTASSIUM BLOOD LEVEL; PRIORITY JOURNAL; PULSE PRESSURE; RISK FACTOR; SUDDEN CARDIAC DEATH; SYSTOLIC BLOOD PRESSURE;

EID: 84879489486     PISSN: 02508095     EISSN: 14219670     Source Type: Journal    
DOI: 10.1159/000351764     Document Type: Article

References (45)

1. US Renal Data System, USRDS 2012 Annual Data Report: Atlas of End-Stage Renal Disease in the United States. Bethesda, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, 2012.
2. Drechsler C, Meinitzer A, Pilz S, Krane V, Tomaschitz A, Ritz E, Marz W, Wanner C: Homoarginine, heart failure, and sudden cardiac death in haemodialysis patients. Eur J Heart Fail 2011; 13: 852-859.
3. Wang AY, Lam CW, Chan IH, Wang M, Lui SF, Sanderson JE: Sudden cardiac death in endstage renal disease patients: a 5-year prospective analysis. Hypertension 2010; 56: 210-216.
4. Bleyer AJ, Hartman J, Brannon PC, Reeves-Daniel A, Satko SG, Russell G: Characteristics of sudden death in hemodialysis patients. Kidney Int 2006; 69: 2268-2273.
5. Karnik JA, Young BS, Lew NL, Herget M, Dubinsky C, Lazarus JM, Chertow GM: Cardiac arrest and sudden death in dialysis units. Kidney Int 2001; 60: 350-357.
6. Pun PH, Lehrich RW, Honeycutt EF, Herzog CA, Middleton JP: Modifiable risk factors associated with sudden cardiac arrest within hemodialysis clinics. Kidney Int 2011; 79: 218-227.
7. Shastri S, Tangri N, Tighiouart H, Beck GJ, Vlagopoulos P, Ornt D, Eknoyan G, Kusek JW, Herzog C, Cheung AK, Sarnak MJ: Predictors of sudden cardiac death: a competing risk approach in the hemodialysis study. Clin J Am Soc Nephrol 2012; 7: 123-130.
8. Parekh RS, Plantinga LC, Kao WH, Meoni LA, Jaar BG, Fink NE, Powe NR, Coresh J, Klag MJ: The association of sudden cardiac death with inflammation and other traditional risk factors. Kidney Int 2008; 74: 1335-1342.
9. Drechsler C, Grootendorst DC, Pilz S, Tomaschitz A, Krane V, Dekker F, Marz W, Ritz E, Wanner C: Wasting and sudden cardiac death in hemodialysis patients: a post hoc analysis of 4D (Die Deutsche Diabetes Dialyse Studie). Am J Kidney Dis 2011; 58: 599-607.
10. Jadoul M, Thumma J, Fuller DS, Tentori F, Li Y, Morgenstern H, Mendelssohn D, Tomo T, Ethier J, Port F, Robinson BM: Modifiable practices associated with sudden death among hemodialysis patients in the dialysis outcomes and practice patterns study. Clin J Am Soc Nephrol 2012; 7: 765-774.
11. Genovesi S, Valsecchi MG, Rossi E, Pogliani D, Acquistapace I, De Cristofaro V, Stella A, Vincenti A: Sudden death and associated factors in a historical cohort of chronic haemodialysis patients. Nephrol Dial Transplant 2009; 24: 2529-2536.
12. Chan KE, Maddux FW, Tolkoff-Rubin N, Karumanchi SA, Thadhani R, Hakim RM: Early outcomes among those initiating chronic dialysis in the United States. Clin J Am Soc Nephrol 2011; 6: 2642-2649.
13. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: Results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'infarto miocardico. Lancet 1999; 354: 447-455.
14. Burr ML, Fehily AM, Gilbert JF, Rogers S, Holliday RM, Sweetnam PM, Elwood PC, Deadman NM: Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: diet and reinfarction trial (DART). Lancet 1989;i:757-761.
15. Gissi-HF Investigators, Tavazzi L, Maggioni AP, et al: Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): a randomised, doubleblind, placebo-controlled trial. Lancet 2008; 372: 1223-1230.
16. Yokoyama M, Origasa H, Matsuzaki M, Matsuzawa Y, Saito Y, Ishikawa Y, Oikawa S, Sasaki J, Hishida H, Itakura H, Kita T, Kitabatake A, Nakaya N, Sakata T, Shimada K, Shirato K: Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis. Lancet 2007; 369: 1090-1098.
17. Kromhout D, Giltay EJ, Geleijnse JM, Alpha Omega Trial Group: n-3 fatty acids and cardiovascular events after myocardial infarction. N Engl J Med 2010; 363: 2015-2026.
18. The ORIGIN Trial Investigators, Bosch J, Gerstein HC, et al: n-3 fatty acids and cardiovascular outcomes in patients with dysglycemia. N Engl J Med 2012; 367: 309-318.
19. Rauch B, Schiele R, Schneider S, Diller F, Victor N, Gohlke H, Gottwik M, Steinbeck G, Del Castillo U, Sack R, Worth H, Katus H, Spitzer W, Sabin G, Senges J: OMEGA, a randomized, placebo-controlled trial to test the effect of highly purified omega-3 fatty acids on top of modern guideline-adjusted therapy after myocardial infarction. Circulation 2010; 122: 2152-2159.
20. Galan P, Kesse-Guyot E, Czernichow S, Briancon S, Blacher J, Hercberg S, SU.FOL.OM3 Collaborative Group: Effects of B vitamins and omega-3 fatty acids on cardiovascular diseases: a randomised placebo controlled trial. BMJ 2010; 341:c6273.
21. Burr ML, Ashfield-Watt PA, Dunstan FD, Fehily AM, Breay P, Ashton T, Zotos PC, Haboubi NA, Elwood PC: Lack of benefit of dietary advice to men with angina: results of a controlled trial. Eur J Clin Nutr 2003; 57: 193-200.
22. Friedman A, Yu Z, Tabbey R, Denski C, Tamez H, Wenger J, Thadhani R, Li Y, Watkins B: Long chain n-3 fatty acids and risk of sudden cardiac death in patients starting hemodialysis. Kidney Int 2013;83:1130-1135.
23. Friedman AN, Yu Z, Tabbey R, Denski C, Tamez H, Wenger J, Thadhani R, Li Y, Watkins BA: Low blood levels of long-chain n-3 polyunsaturated fatty acids in US hemodialysis patients: clinical implications. Am J Nephrol 2012; 36: 451-458.
24. Zeleniuch-Jacquotte A, Chajes V, Van Kappel AL, Riboli E, Toniolo P: Reliability of fatty acid composition in human serum phospholipids. Eur J Clin Nutr 2000; 54: 367-372.
25. Department of Health and Human Services: The International Classification of Diseases, ed 9 revised, Clinical Modification: ICD-9-CM. Washington, Department of Health and Human Services, 1980.
26. Zheng ZJ, Croft JB, Giles WH, Mensah GA: Sudden cardiac death in the United States, 1989 to 1998. Circulation 2001; 104: 2158-2163.
27. Herzog CA, Li S, Weinhandl ED, Strief JW, Collins AJ, Gilbertson DT: Survival of dialysis patients after cardiac arrest and the impact of implantable cardioverter defibrillators. Kidney Int 2005; 68: 818-825.
28. Wolf M, Shah A, Gutierrez O, Ankers E, Monroy M, Tamez H, Steele D, Chang Y, Camargo CA Jr, Tonelli M, Thadhani R: Vitamin D levels and early mortality among incident hemodialysis patients. Kidney Int 2007; 72: 1004-1013.
29. Zou H, Hastie T: Regularization and variable selection via the elastic net. J R Statist Soc B 2005; 67: 301-320.
30. US Renal Data System, USRDS 2008 Annual Data Report: Atlas of End-Stage Renal Disease in the United States. Bethesda, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, 2008.
31. Harris W, Schacky CV: The omega-3 index: a new risk factor for death from coronary heart disease? Prev Med 2004; 39: 212-220.
32. Friedman AN, Fadem SZ: Reassessment of albumin as a nutritional marker in kidney disease. J Am Soc Nephrol 2010; 21: 223-230.
33. Mountantonakis S, Deo R: Biomarkers in atrial fibrillation, ventricular arrhythmias, and sudden cardiac death. Cardiovasc Ther 2012; 30:e74-e80.
34. Mozaffarian D, Wu JH: Omega-3 fatty acids and cardiovascular disease: effects on risk factors, molecular pathways, and clinical events. J Am Coll Cardiol 2011; 58: 2047-2067.
35. Mozaffarian D, Wu JH: (n-3) fatty acids and cardiovascular health: are effects of EPA and DHA shared or complementary? J Nutr 2012; 142: 614S-625S.
36. Sprecher H: The roles of anabolic and catabolic reactions in the synthesis and recycling of polyunsaturated fatty acids. Prostaglandins Leukot Essent Fatty Acids 2002; 67: 79-83.
37. Saifullah A, Watkins BA, Saha C, Li Y, Moe SM, Friedman AN: Oral fish oil supplementation raises blood omega-3 levels and lowers C-reactive protein in haemodialysis patients -A pilot study. Nephrol Dial Transplant 2007; 22: 3561-3567.
38. Mozaffarian D, Rimm EB: Fish intake, contaminants, and human health: evaluating the risks and the benefits. JAMA 2006; 296: 1885-1899.
39. Mozaffarian D, Wu JH: Omega-3 fatty acids and cardiovascular disease: effects on risk factors, molecular pathways, and clinical events. J Am Coll Cardiol 2011; 58: 2047-2067.
40. McLennan PL, Bridle TM, Abeywardena MY, Charnock JS: Dietary lipid modulation of ventricular fibrillation threshold in the marmoset monkey. Am Heart J 1992; 123: 1555-1561.
41. McLennan PL: Relative effects of dietary saturated, monounsaturated, and polyunsaturated fatty acids on cardiac arrhythmias in rats. Am J Clin Nutr 1993; 57: 207-212.
42. Chiuve SE, Rimm EB, Sandhu RK, Bernstein AM, Rexrode KM, Manson JE, Willett WC, Albert CM: Dietary fat quality and risk of sudden cardiac death in women. Am J Clin Nutr 2012; 96: 498-507.
43. Klassen PS, Lowrie EG, Reddan DN, DeLong ER, Coladonato JA, Szczech LA, Lazarus JM, Owen WF Jr: Association between pulse pressure and mortality in patients undergoing maintenance hemodialysis. JAMA 2002; 287: 1548-1555.
44. London B, Albert C, Anderson ME, Giles WR, Van Wagoner DR, Balk E, Billman GE, Chung M, Lands W, Leaf A, McAnulty J, Martens JR, Costello RB, Lathrop DA: Omega-3 fatty acids and cardiac arrhythmias: prior studies and recommendations for future research: a report from the national heart, lung, and blood institute and office of dietary supplements omega-3 fatty acids and their role in cardiac arrhythmogenesis workshop. Circulation 2007; 116:e320-e335.
45. Harris WS: The omega-3 index: clinical utility for therapeutic intervention. Curr Cardiol Rep 2010; 12: 503-508.