Molecular basis of ligand recognition by OASS from E. histolytica: Insights from structural and molecular dynamics simulation studies

Biochimica et Biophysica Acta - General Subjects

Volumn 1830, Issue 10, 2013, Pages 4573-4583

  Raj, Isha ^a   Mazumder, Mohit ^a   Gourinath, Samudrala ^a  

^a JAWAHARLAL NEHRU UNIVERSITY   (India)

Author keywords

Active site cleft; Conformational change; Cysteine biosynthetic pathway; Inhibition; Ligand binding; O acetyl serine sulfhydrylase

Indexed keywords

ISOLEUCINE; LYSINE; METHIONINE; NITROGEN; O ACETYL SERINE SULFHYDRYLASE; PYRIDOXAL 5 PHOSPHATE; SCHIFF BASE; TETRAPEPTIDE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENTAMOEBA HISTOLYTICA; LIGAND BINDING; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

ACTIVE SITE CLEFT; CONFORMATIONAL CHANGE; CYSTEINE BIOSYNTHETIC PATHWAY; INHIBITION; LIGAND BINDING; O-ACETYL SERINE SULFHYDRYLASE;

CRYSTALLOGRAPHY, X-RAY; CYSTEINE SYNTHASE; ENTAMOEBA HISTOLYTICA; LIGANDS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION;

ENTAMOEBA HISTOLYTICA; TETRA;

EID: 84879469871     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2013.05.041     Document Type: Article

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