Randomized controlled trial: Multimodal anxiety and social skill intervention for adolescents with autism spectrum disorder

Journal of Autism and Developmental Disorders

Volumn 43, Issue 2, 2013, Pages 382-394

  White, Susan W ^a   Ollendick, Thomas ^a   Albano, Anne Marie ^b   Oswald, Donald ^c   Johnson, Cynthia ^d   Southam Gerow, Michael A ^c,f   Kim, Inyoung ^a   Scahill, Lawrence ^e  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^e YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adolescence; Anxiety; Autism; Treatment

Indexed keywords

ADOLESCENT; ANXIETY DISORDER; ARTICLE; AUTISM; CHILD; CLINICAL ARTICLE; DISEASE SEVERITY; EFFECT SIZE; FEASIBILITY STUDY; FEMALE; GROUP THERAPY; HUMAN; INTERVENTION STUDY; MALE; OUTCOME ASSESSMENT; PILOT STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SCHOOL CHILD; SOCIAL ADAPTATION;

ADOLESCENT; ANXIETY; BEHAVIOR THERAPY; CHILD; CHILD DEVELOPMENT DISORDERS, PERVASIVE; FEMALE; HUMANS; MALE; PATIENT SATISFACTION; PILOT PROJECTS; PSYCHOTHERAPY, GROUP; SOCIAL BEHAVIOR; TREATMENT OUTCOME;

EID: 84879467872     PISSN: 01623257     EISSN: 15733432     Source Type: Journal    
DOI: 10.1007/s10803-012-1577-x     Document Type: Article

References (78)

1. Barrett, P. M.; Dadds, M. R.; & Rapee, R. M. (1996). Family treatment of childhood anxiety: A controlled trial. Journal of Consulting and Clinical Psychology, 64, 333-342.
2. Bass, M. M.; Duchowny, C. A.; & Llabre, M. M. (2009). The effect of therapeutic horseback riding on social functioning in children with autism. Journal of Autism and Developmental Disorders, 39(9), 1261-1267. doi: 10.1007/s10803-009-0734-3.
3. Beaumont, R.; & Sofronoff, K. (2008). A multi-component social skills intervention for children with asperger syndrome: The junior detective training program. Journal of Child Psychology and Psychiatry, 49(7), 743-753. doi: 10.1111/j.1469-7610.2008.01920.x.
4. Bellini, S. (2006). The development of social anxiety in adolescents with autism spectrum disorders. Focus on Autism and Other Developmental Disabilities, 21, 138-145.
5. Brown, T. A.; & McNiff, J. (2009). Specificity of autonomic arousal to DSM-IV panic disorder and posttraumatic stress disorder. Behaviour Research and Therapy, 47, 487-493. doi: 10.1016/j.brat.2009.02.016.
6. Campbell, J. M.; Ferguson, J. E.; Herzinger, C. V.; Jackson, J. N.; & Marino, C. A. (2004). Combined descriptive and explanatory information improves peers' perceptions of autism. Research in Developmental Disabilities, 25, 321-339.
7. Chalfant, A.; Rapee, R.; & Carroll, L. (2007). Treating anxiety disorders in children with high functioning autism spectrum disorders: A controlled trial. Journal of Autism and Developmental Disorders, 37, 1842-1857. doi: 10.1007/s10803-006-0318-4.
8. Chambless, D. L.; & Hollon, S. D. (1998). Defining empirically supported therapies. Journal of Consulting and Clinical Psychology, 66, 7-18.
9. Chorpita, B. F. (2007). Modular cognitive-behavioral therapy for childhood anxiety disorders. In J. B. Persons (Ed.), Guides to individualized evidence-based treatment. Guilford: New York.
10. Clark, L. A.; & Watson, D. (1991). Tripartite model of anxiety and depression: Psychometric evidence and taxonomic implications. Journal of Abnormal Psychology, 100, 316-336.
11. Clarke, G.; Hops, H.; Lewinsohn, P. M.; Andrews, J.; Seeley, J. R.; & Williams, J. (1992). Cognitive-behavioral group treatment of adolescent depression: Prediction of outcome. Behavior Therapy, 23, 341-354.
12. Constantino, J. N.; & Gruber, C. P. (2005). Social responsiveness scale (SRS). Los Angeles, CA: Western Psychological Services.
13. Costello, E. J.; Egger, H. L.; & Angold, A. (2004). Developmental epidemiology of anxiety disorders. In T. H. Ollendick & J. S. March (Eds.), Phobic and anxiety disorders in children and adolescents. New York: Oxford University Press.
14. Dalton, K. D.; Nacewicz, B. M.; Alexander, A. L.; & Davidson, R. J. (2007). Gaze-fixation, brain activation, and amygdala volume in unaffected siblings of individuals with autism. Biological Psychiatry, 61, 512-520. doi: 10.1016/j.biopsych.2006.05.019.
15. deBruin, E. I.; Ferdinand, R. F.; Meester, S.; De Nijs, F. A.; & Verheij, F. (2007). High rates of psychiatric co-morbidty in PDD-NOS. Journal of Autism and Developmental Disorders, 37, 877-886.
16. Fidler, F.; Faulkner, C.; & Cumming, G. (2008). Analyzing and presenting results. In A. M. Nezu & C. M. Nezu (Eds.), Evidence-based outcome research: A practical guide to conducting randomized trials for psychosocial interventions (pp. 315-334). New York: Oxford University Press.
17. Gadow, K. D.; & Sprafkin, J. (1997). Adolescent symptom inventory-4 screening manual. Stony Brook, NY: Checkmate Plus.
18. Gadow, K. D.; & Sprafkin, J. (1998). Adolescent symptom inventory-4 norms manual. Stony Brook, NY: Checkmate Plus.
19. Gaynor, S. T.; Lawrence, P. S.; & Nelson-Gray, R. O. (2006). Cognitive-behavioral therapy for adolescent depression: Review, preliminary findings, and implications for theory and practice. Behavior Modification, 30, 647-672. doi: 10.1177/0145445504272979.
20. Guy W. (1976). ECDEU assessment manual for psychopharmacology. US Dept Health, Education, and Welfare publication; ADM No. 76-338 (pp. 218-222)). Rockville, MD: National Institute of Mental Health.
21. Harnum, M.; Duffy, J.; & Ferguson, D. A. (2007). Adults' versus children's percentions of a child with autism or attention deficit hyperactivity disorder. Journal of Autism and Developmental Disorders, 37, 1337-1343.
22. Honda, H.; Shimizu, Y.; Imai, M.; & Nitto, Y. (2005). Cumulative incidence of childhood autism: A total population study of better accuracy and precision. Developmental Medicine and Child Neurology, 47, 10-18. doi: 10.1192/bjp.169.2.228.
23. Hudson, J. L.; Rapee, R. M.; Deveney, C.; Schniering, C. A.; Lyneham, H. J.; & Bovopoulos, N. (2009). Cognitive-behavioral treatment versus an active control for children and adolescents with anxiety disorders: A randomized trial. Journal of the American Academy of Child and Adolescent Psychiatry, 48, 533-544. doi: 10.1097/CHI.0b013e31819c2401.
24. Jacobson, N. S.; & Truax, P. (1991). Clinical significance: A statistical approach to defining meaningful change in psychotherapy research. Journal of Consulting and Clinical Psychology, 59, 12-19.
25. Joseph, R. M.; Ehrman, K.; McNallly, R.; & Keehn, B. (2008). Affective response to eye contact and face recognition ability in children with ASD. Journal of the International Neuropsychological Society, 14, 947-955.
26. Joshi, G.; Petty, C.; Wozniak, J.; Henin, A.; Fried, R.; Galdo, M.; et al. (2010). The heavy burden of psychiatric comorbidity in youth with autism spectrum disorders: A large comparative study of a psychiatrically referred population. Journal of Autism & Developmental Disorders. Advance online publication. doi: 10.1007/s10803-010-0996-9.
27. Kendall, P. C.; Flannery-Schroeder, E.; Panichelli-Mindel, S. M.; Southam-Gerow, M.; Henin, A.; & Warman, M. (1997). Therapy for youths with anxiety disorders: A second randomized clinical trial. Journal of Consulting and Clinical Psychology, 65(3), 366-380. doi: 10.1037/0022-006X.65.3.366.
28. Kendall, P. C.; Hudson, J. L.; Gosch, E.; Flannery-Schroeder, E.; & Suveg, C. (2008). Cognitive-behavioral therapy for anxiety disordered youth: A randomized clinical trial evaluating child and family modalities. Journal of Consulting and Clinical Psychology, 76, 282-297.
29. Kim, Y. S.; Bennett, L. L.; Koh, Y. J.; Fombonne, E.; Laska, E.; Lim, E. C.; et al. (2011). Prevalence of autism spectrum disorders in a total population sample. American Journal of Psychiatry, 168, 904-912. doi: 10.1176/appi.ajp. 2011.10101532.
30. Kleinhans, N. M.; Richards, T.; Weaver, K.; Johnson, L. C.; Greenson, J.; Dawson, G.; et al. (2010). Association between amygdala response to emotional faces and social anxiety in autism spectrum disorders. Neuropsychologia, 48(12), 3665-3670. doi: 10.1016/j.neuropsychologia.2010.07.022.
31. Klin, A.; & Volkmar, F. R. (2000). Treatment and intervention guidelines for individuals with asperger syndrome. In A. Klin, F. R. Volkmar, & S. S. Sparrow (Eds.), Asperger syndrome (pp. 340-366). New York: Guilford Press.
32. Kraemer, H. C.; & Kupfer, D. J. (2006). Size of treatment effects and their importance to clinical research and practice. Biological Psychiatry, 59, 990-996.
33. Kraemer, H.; Minitz, J.; Noda, A.; Tinklenberg, J.; & Yesavage, J. A. (2006). Caution regarding the use of pilot studies to guide power calculations for study proposals. Archives of General Psychiatry, 63, 484-489.
34. Kyllianinen, A.; & Hietanen, J. (2006). Skin conductance responses to another person's gaze in children with autism. Journal of Autism and Developmental Disorders, 36(4), 517-525. doi: 10.1007/s10803-006-0091-4.
35. Leon, A. C.; Davis, L. L.; & Kraemer, H. C. (2011). The role and interpretation of pilot studies in clinical research. Journal of Psychiatric Research, 45, 626-629. doi: 10.1016/j.jpsychires.2010.10.008.
36. Leyfer, O. T.; Folstein, S. E.; Bacalman, S.; Davis, N. O.; Dinh, E.; Morgan, J.; et al. (2006). Comorbid psychiatric disorders in children with autism: Interview development and rates of disorders. Journal of Autism and Developmental Disorders, 36, 849-861.
37. Lopata, C.; Thomeer, M. L.; Volker, M. A.; Nida, R. E.; Lee, G. K.; Toomey, J. A.; et al. (2010). RCT of a manualized social treatment for high-functioning autism spectrum disorders. Journal of Autism and Developmental Disorders, 40, 1297-1310. doi: 10.1007/s10803-010-0989-8.
38. Lord, C.; Rutter, M.; DiLavore, P. C.; & Risi, S. (2002). Autism diagnostic observation schedule. Los Angeles: Western Psychological Services.
39. Lord, C.; Rutter, M.; & Le Couteur, A. (1994). Autism diagnostic interview - revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24(5), 659-685. doi: 10.1007/BF02172145.
40. Mazefsky, C. A.; Hughes, A. J.; Oswald, D. P.; & Lainhart, J. E. (2012). Lack of correspondence between self- and parent-report on structured psychiatric interview of adolescents with high-functioning autism spectrum disorders. Oral presentation at the International Meeting for Autism Research, Toronto, Canada.
41. Mazefsky, C. A.; Kao, J.; & Oswald, D. P. (2011). Preliminary evidence suggesting caution in the use of psychiatric self-report measures with adolescents with high-functioning autism spectrum disorders. Research in Autism Spectrum Disorders, 5, 164-174. doi: 10.1016/j.rasd.2010.03.006.
42. Merikangas, K. R.; He, J.; Burstein, M.; Swanson, S. A.; Avenevoli, S.; et al. (2010). Lifetime prevalence of mental disorders in US adolescents: Results from the National Comorbidity Survey Replication-Adolescent Supplement (NCS-A). Journal of the American Academy of Child and Adolescent Psychiatry, 49(10), 980-989.
43. Morris, S. B.; & DeShon, R. P. (2002). Combining effect size estimates in meta-analysis with repeated measures and independent-group designs. Psychological Methods, 7(1), 105-125.
44. Myles, B.; Barnhill, G.; Hagiwara, T.; Griswold, D.; & Simpson, R. (2001). A synthesis of studies on the intellectual, academic, social/emotional and sensory characteristics of children with asperger syndrome. Education and Training in Mental Retardation and Developmental Disabilities, 36, 304-311.
45. Ochs, E.; Kremer-Sadlik, T.; Solomon, O.; & Gainer Sirota, K. (2001). Inclusion as social practice: Views of children with autism. Social Development, 10, 399-419.
46. Ollendick, T. H.; Ost, L.-G.; Reuterskiold, L.; Costa, N.; Cederlund, R.; Sirbu, C.; et al. (2009). One-session treatment of specific phobias in youth: A randomized clinical trial in the United States and Sweden. Journal of Consulting and Clinical Psychology, 77, 504-516.
47. Pavuluri, M. N.; Graczyk, P. A.; Henry, D. B.; Carbrat, J. A.; Heidenreich, J.; & Miklowitz, D. J. (2004). Child- and family-focused cognitive-behavioral therapy for pediatric bipolar disorder: Development and preliminary results. Journal of the American Academy of Child Psychiatry, 2004(43), 528-537. doi: 10.1097/00004583-200405000-00006.
48. Pitman, E. J. G. (1937). Significance tests which may be applied to samples from any population. Royal Statistical Society Supplement, 4(119-130), 225-232.
49. Pocock, S. J. (1983). Clinical trials: A practical approach. Chichester: Wiley.
50. Reaven, J. A.; Blakeley-Smith, A.; Nichols, S.; Dasari, M.; Flanigan, E.; & Hepburn, S. (2009). Cognitive-behavioral group treatment for anxiety symptoms in children with high-functioning autism spectrum disorders: A pilot study. Focus on Autism and Other Developmental Disabilities, 24(1), 27-37.
51. Research Units on Pediatric Psychopharmacology [RUPP] Autism Network. (2007). Parent training for children with pervasive developmental disorders: A multi-site feasibility trial. Behavioral Interventions, 22, 179-199. doi: 10.1002/bin.236.
52. Research Units on Pediatric Psychopharmacology Anxiety Study Group. (2002). The pediatric anxiety rating scale (PARS): Development and psychometric properties. Journal of the American Academy of Child & Adolescent Psychiatry, 41, 1061-1069.
53. Rutter, M.; Lord, C.; & Le Couteur, A. (2003). Autism diagnostic interview revised manual. Torrance, CA: Wester Psychological Services.
54. Shatayermann, O. (2007). Peer victimization in adolescents and young adults diagnosed with asperger's syndrome: A link to depressive symptomatology, anxiety symptomatology, and suicidal ideation. Issues in Comprehensive Pediatric Nursing, 30, 87-107. doi: 10.1080/01460860701525089.
55. Silverman, W. K.; & Albano, A. M. (1996). Anxiety disorders interview schedule for DSM-IV. San Antonio, TX: The Psychological Corporation.
56. Silverman, W.; Kurtines, W.; Ginsburg, G.; Weems, C.; Rabian, B.; & Serafini, L. (1999). Contingency management, self-control, and education support in the treatment of childhood phobic disorders: A randomized clinical trial. Journal of Consulting and Clinical Psychology, 67, 675-687.
57. Silverman, W. K.; Saavedra, L. M.; & Pina, A. A. (2001). Test-retest reliability of anxiety symptoms and diagnoses with anxiety disorders interview schedule for DSM-IV: Child and parent versions. Journal of the American Academy of Child and Adolescent Psychiatry, 40(8), 937-944. doi: 10.1097/00004583- 200108000-00016.
58. Smith, T.; Scahill, L.; Dawson, G.; Guthrie, D.; Lord, C.; Odom, S.; et al. (2007). Designing research studies on psychosocial interventions in autism. Journal of Autism and Developmental Disorders, 37, 354-366. doi: 10.1007/s10803-006-0173-3.
59. Sofronoff, K.; Attwood, T.; & Hinton, S. (2005). A randomised controlled trial of a CBT intervention for anxiety in children with asperger syndrome. Journal of Child Psychology and Psychiatry, 46(11), 1152-1160. doi: 10.1111/j.1469-7610.2006.00411.x.
60. Sparrow, S. S.; Cicchetti, D. V.; & Balla, D. A. (2005). Vineland-II adaptive behavior scales (2nd ed.). Circle Pines, MN: AGS Publishing.
61. Stattin, H.; & Kerr, M. (2009). Challenges in intervention research on adolescent development. Journal of Adolescence, 32, 1437-1442. doi: 10.1016/j.adolescence.2009.10.010.
62. Sukhodolsky, D. G.; Scahill, L.; Gadow, K. D.; Arnold, E.; Aman, M. G.; McDougle, C. J.; et al. (2008). Parent-rated anxiety symptoms in children with pervasive developmental disorders: Frequency and association with core autism symptoms and cognitive functioning. Journal of Abnormal Child Psychology, 36, 117-128.
63. Swaim, K. F.; & Morgan, S. B. (2001). Children's attitudes and behavioral intentions toward a peer with autistic behaviors: Does a brief educational intervention have an effect? Journal of Autism and Developmental Disorders, 31, 195-205.
64. TADS Team. (2004). Fluoxetine, cognitive-behavioral therapy, and their combination for adolescents with depression. Journal of the American Medical Association, 292, 807-820.
65. Trosper, S. E.; Whitton, S. W.; Brown, T. A.; & Pincus, D. B. (2012). Understanding the latent structure of the emotional disorders in children and adolescents. Journal of Abnormal Child Psychology, 40, 621-632. doi: 10.1007/s10802-011-9582-7.
66. Tse, J.; Strulovich, J.; Tagalakis, V.; Meng, L.; & Fombonne, E. (2007). Social skills training for adolescents with asperger syndrome and high-functioning autism. Journal of Autism and Developmental Disorders, 37, 1960-1968.
67. United States Centers for Disease Control and Prevention. (2012). Prevalence of autism spectrum disorders-autism and developmental disabilities monitoring network, United States, 2008. MMWR Surveill Summ, 61 (No. SS-3).
68. Wagner, A.; Lecavalier, L.; Arnold, L. E.; Aman, M. G.; Scahill, L.; Stigler, K. A.; et al. (2007). Developmental disabilities modification of children's global assessment scale (DD-CGAS). Biological Psychiatry, 61, 504-511. doi: 10.1016/j.biopsych.2007.01.001.
69. Walkup, J. T.; Albano, A. M.; Piacentini, J. C.; Birmaher, B.; Compton, S. N.; Sherrill, J. T.; et al. (2008). Cognitive behavioral therapy, Sertraline, or a combination in childhood anxiety. New England Journal of Medicine, 359, 2753-2766.
70. Wechsler, D. (1999). Wechsler abbreviated scale of intelligence (WASI). San Antonio, TX: Harcourt Assessment.
71. White, S.W.; Albano, A.; Johnson, C.; Kasari, C.; Ollendick, T.; Klin, A.; et al. (2010a). Development of a cognitive-behavioral intervention program to treat anxiety and social deficits in teens with high-functioning autism. Clinical Child and Family Psychology Review, 13(1), 77-90. doi: 10.1007/s10567-009-0062-3.
72. White, S. W.; Koenig, K.; & Scahill, L. (2010b). Group therapy to improve social skills in adolescents with high-functioning autism spectrum disorders. Focus on Autism and Other Developmental Disabilities, 25(4), 209-219. doi: 10.1177/1088357610380595.
73. White, S.W.; Ollendick, T.; Scahill, L.; Oswald, D.; & Albano, A. (2009a). Preliminary efficacy of a cognitive-behavioral treatment program for anxious youth with autism spectrum disorders. Journal of Autism and Developmental Disorders, 39, 1652-1662. doi: 10.1007/s10803-009-0801-9.
74. White, S. W.; Oswald, D.; Ollendick, T.; & Scahill, L. (2009b). Anxiety in children and adolescents with autism spectrum disorders. Clinical Psychology Review, 29(3), 216-229. doi: 10.1016/j.cpr.2009.01.003.
75. White, S. W.; Schry, A. R.; & Maddox, B. M. (2012). Brief report: The assessment of anxiety in high-functioning adolescents with autism spectrum disorder. Journal of Autism and Developmental Disorders. Advance online publication. doi: 10.1007/s10803-011-1353-3.
76. Witwer, A. N.; & Lecavalier, L. (2010). Validity of comorbid psychiatric disorders in youngsters with autism spectrum disorders. Journal of Developmental and Physical Disabilities, 22, 367-380. doi: 10.1007/s10882-010- 9194-0.
77. Wood, J. J.; Drahota, A.; Sze, K.; Har, K.; Chiu, A.; & Langer, D. A. (2009). Cognitive behavioral therapy for anxiety in children with autism spectrum disorders: A randomized, controlled trial. Journal of Child Psychology and Psychiatry, 50(3), 224-234. doi: 10.1111/j.1469-7610.2008.01948.x.
78. Wood, J. J.; Piacentini, J. C.; Bergman, R. L.; McCracken, J.; & Barrios, V. (2002). Concurrent validity of the anxiety disorders section of the anxiety disorders interview schedule for DSM-IV: Child and parent versions. Journal of Clinical Child & Adolescent Psychology, 31(3), 335-342. doi: 10.1207/153744202760082595.