Cellular biophysical dynamics and ion channel activities detected by AFM-based nanorobotic manipulator in insulinoma β-cells

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 9, Issue 5, 2013, Pages 636-645

  Yang, Ruiguo ^a   Xi, Ning ^a,b   Lai, King Wai Chiu ^a,b   Patterson, Kevin C ^c   Chen, Hongzhi ^a   Song, Bo ^a   Qu, Chengeng ^a   Zhong, Beihua ^c,d   Wang, Donna H ^c,e  

^a Michigan State University   (United States)

^b CITY UNIVERSITY OF HONG KONG   (Hong Kong)

^c MICHIGAN STATE UNIVERSITY   (United States)

^d GUANGZHOU MEDICAL UNIVERSITY   (China)

^e MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

AFM nanorobotics; Cellular stiffness; Insulinoma cells; Ion channel activities

Indexed keywords

AFM; BIOPHYSICAL PROPERTIES; BIPHASIC RESPONSE; INSULIN SECRETION; INSULINOMA; ION CHANNEL; NANOROBOTIC MANIPULATOR; OPTICAL INVESTIGATION;

BIOMECHANICS; CALCIUM; ELECTROMECHANICAL COUPLING; GLUCOSE; INSULIN; IONS; PHYSIOLOGY; STIFFNESS; WELL STIMULATION;

NANOROBOTICS;

CALCIUM ION; CAPSAICIN; GLUCOSE; ION CHANNEL; VANILLOID RECEPTOR 1;

ACTIN FILAMENT; ANIMAL CELL; ARTICLE; ATOMIC FORCE MICROSCOPY; CALCIUM CELL LEVEL; INSULIN RELEASE; INSULINOMA; NONHUMAN; PANCREAS ISLET BETA CELL; RAT; YOUNG MODULUS;

BIOPHYSICAL PROCESSES; CALCIUM; CAPSAICIN; CELL LINE, TUMOR; CYCLIC AMP; GLUCOSE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; INSULINOMA; ION CHANNELS; ISLETS OF LANGERHANS; MICROSCOPY, ATOMIC FORCE; NANOTECHNOLOGY; PANCREATIC NEOPLASMS; ROBOTICS;

EID: 84879464376     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2012.10.011     Document Type: Article

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