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Volumn 170, Issue 5, 2013, Pages 521-532

Genome-wide linkage analyses of 12 endophenotypes for schizophrenia from the consortium on the genetics of schizophrenia

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CHROMOSOME 3P; CLINICAL ASSESSMENT; CLINICAL EVALUATION; EMOTION; ENDOPHENOTYPE; FAMILY ASSESSMENT; GENETIC ASSOCIATION; GENOTYPE; HERITABILITY; HUMAN; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; PEDIGREE ANALYSIS; PREPULSE INHIBITION; PRIORITY JOURNAL; RECOGNITION; SCHIZOPHRENIA; SIBLING; SINGLE NUCLEOTIDE POLYMORPHISM; ADOLESCENT; BLOOD; FEMALE; GENETIC LINKAGE; GENETIC PREDISPOSITION; GENETICS; MALE; MIDDLE AGED; MULTICENTER STUDY; NEUROPSYCHOLOGICAL TEST; PSYCHOLOGY;

EID: 84879446191     PISSN: 0002953X     EISSN: 15357228     Source Type: Journal    
DOI: 10.1176/appi.ajp.2012.12020186     Document Type: Article
Times cited : (105)

References (92)
  • 1
    • 0030813634 scopus 로고    scopus 로고
    • A turning point in schizophrenia genetics
    • Karayiorgou M, Gogos JA: A turning point in schizophrenia genetics. Neuron 1997; 19: 967-979
    • (1997) Neuron , vol.19 , pp. 967-979
    • Karayiorgou, M.1    Gogos, J.A.2
  • 2
    • 33845878534 scopus 로고    scopus 로고
    • Statistical genetics concepts and approaches in schizophrenia and related neuropsychiatric research
    • Schork NJ, Greenwood TA, Braff DL: Statistical genetics concepts and approaches in schizophrenia and related neuropsychiatric research. Schizophr Bull 2007; 33: 95-104
    • (2007) Schizophr Bull , vol.33 , pp. 95-104
    • Schork, N.J.1    Greenwood, T.A.2    Braff, D.L.3
  • 3
    • 33846642542 scopus 로고    scopus 로고
    • The genetics of schizophrenia
    • Sullivan PF: The genetics of schizophrenia. PLoS Med 2005; 2: e212
    • (2005) PLoS Med , vol.2
    • Sullivan, P.F.1
  • 4
    • 12344327212 scopus 로고    scopus 로고
    • Schizophrenia genes, gene expression, and neuropathology: On the matter of their convergence
    • image 45
    • Harrison PJ, Weinberger DR: Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Mol Psychiatry 2005; 10: 40-68; image 45;
    • (2005) Mol Psychiatry , vol.10 , pp. 40-68
    • Harrison, P.J.1    Weinberger, D.R.2
  • 5
    • 23744471251 scopus 로고    scopus 로고
    • Erratum and 10: 420
    • Erratum in Mol Psychiatry 2005; 10: 804 and 10: 420
    • (2005) Mol Psychiatry , vol.10 , pp. 804
  • 6
    • 33645986682 scopus 로고    scopus 로고
    • Schizophrenia susceptibility genes: Emergence of positional candidates and future directions
    • Gogos JA, Gerber DJ: Schizophrenia susceptibility genes: emergence of positional candidates and future directions. Trends Pharmacol Sci 2006; 27: 226-233
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 226-233
    • Gogos, J.A.1    Gerber, D.J.2
  • 7
    • 0035121790 scopus 로고    scopus 로고
    • Genetics of schizophrenia and the new millennium: Progress and pitfalls
    • Baron M: Genetics of schizophrenia and the new millennium: progress and pitfalls. Am J Hum Genet 2001; 68: 299-312
    • (2001) Am J Hum Genet , vol.68 , pp. 299-312
    • Baron, M.1
  • 9
    • 0002861128 scopus 로고    scopus 로고
    • The importance of endophenotypes in studies of the genetics of schizophrenia
    • Edited by Davis KL, Charney D, Coyle JT, Nemeroff C. Baltimore, Lippincott, Williams & Wilkins
    • Braff DL, Freedman R: The importance of endophenotypes in studies of the genetics of schizophrenia, in Neuropsychopharmacology: The Fifth Generation of Progress. Edited by Davis KL, Charney D, Coyle JT, Nemeroff C. Baltimore, Lippincott, Williams & Wilkins, 2002, pp 703-716
    • (2002) Neuropsychopharmacology: The Fifth Generation of Progress , pp. 703-716
    • Braff, D.L.1    Freedman, R.2
  • 11
    • 0038823525 scopus 로고    scopus 로고
    • The endophenotype concept in psychiatry: Etymology and strategic intentions
    • Gottesman II, Gould TD: The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 2003; 160: 636-645
    • (2003) Am J Psychiatry , vol.160 , pp. 636-645
    • Gottesman, I.I.1    Gould, T.D.2
  • 12
    • 55449120805 scopus 로고    scopus 로고
    • Genetic mapping in human disease
    • Altshuler D, Daly MJ, Lander ES: Genetic mapping in human disease. Science 2008; 322: 881-888
    • (2008) Science , vol.322 , pp. 881-888
    • Altshuler, D.1    Daly, M.J.2    Lander, E.S.3
  • 14
    • 31544449191 scopus 로고    scopus 로고
    • Using linkage genome scans to improve power of association in genome scans
    • Roeder K, Bacanu SA, Wasserman L, Devlin B: Using linkage genome scans to improve power of association in genome scans. Am J Hum Genet 2006; 78: 243-252
    • (2006) Am J Hum Genet , vol.78 , pp. 243-252
    • Roeder, K.1    Bacanu, S.A.2    Wasserman, L.3    Devlin, B.4
  • 15
  • 16
    • 0034891977 scopus 로고    scopus 로고
    • Human studies of prepulse inhibition of startle: Normal subjects, patient groups, and pharmacological studies
    • Braff DL, Geyer MA, Swerdlow NR: Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies. Psychopharmacology (Berl) 2001; 156: 234-258
    • (2001) Psychopharmacology (Berl) , vol.156 , pp. 234-258
    • Braff, D.L.1    Geyer, M.A.2    Swerdlow, N.R.3
  • 18
    • 33845307916 scopus 로고    scopus 로고
    • Genetic and environmental influences on sensory gating of mid-latency auditory evoked responses: A twin study
    • Anokhin AP, Vedeniapin AB, Heath AC, Korzyukov O, Boutros NN: Genetic and environmental influences on sensory gating of mid-latency auditory evoked responses: a twin study. Schizophr Res 2007; 89: 312-319
    • (2007) Schizophr Res , vol.89 , pp. 312-319
    • Anokhin, A.P.1    Vedeniapin, A.B.2    Heath, A.C.3    Korzyukov, O.4    Boutros, N.N.5
  • 24
    • 0020533968 scopus 로고
    • Visual sustained attention: Image degradation produces rapid sensitivity decrement over time
    • Nuechterlein KH, Parasuraman R, Jiang Q: Visual sustained attention: image degradation produces rapid sensitivity decrement over time. Science 1983; 220: 327-329
    • (1983) Science , vol.220 , pp. 327-329
    • Nuechterlein, K.H.1    Parasuraman, R.2    Jiang, Q.3
  • 37
    • 84870469320 scopus 로고    scopus 로고
    • American Psychiatric Association:, 4th ed, Text Revision. Washington, DC, American Psychiatric Publishing
    • American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 4th ed, Text Revision. Washington, DC, American Psychiatric Publishing, 2000
    • (2000) Diagnostic and Statistical Manual of Mental Disorders
  • 40
    • 0032231941 scopus 로고    scopus 로고
    • PedCheck: A program for identification of genotype incompatibilities in linkage analysis
    • O'Connell JR, Weeks DE: PedCheck: a program for identification of genotype incompatibilities in linkage analysis. Am J Hum Genet 1998; 63: 259-266
    • (1998) Am J Hum Genet , vol.63 , pp. 259-266
    • O'Connell, J.R.1    Weeks, D.E.2
  • 41
    • 0036338150 scopus 로고    scopus 로고
    • Merlin: Rapid analysis of dense genetic maps using sparse gene flow trees
    • Abecasis GR, Cherny SS, Cookson WO, Cardon LR: Merlin: rapid analysis of dense genetic maps using sparse gene flow trees. Nat Genet 2002; 30: 97-101
    • (2002) Nat Genet , vol.30 , pp. 97-101
    • Abecasis, G.R.1    Cherny, S.S.2    Cookson, W.O.3    Cardon, L.R.4
  • 43
    • 0031966959 scopus 로고    scopus 로고
    • Multipoint quantitative-trait linkage analysis in general pedigrees
    • Almasy L, Blangero J: Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet 1998; 62: 1198-1211
    • (1998) Am J Hum Genet , vol.62 , pp. 1198-1211
    • Almasy, L.1    Blangero, J.2
  • 44
    • 0031439473 scopus 로고    scopus 로고
    • Bivariate quantitative trait linkage analysis: Pleiotropy versus co-incident linkages
    • Almasy L, Dyer TD, Blangero J: Bivariate quantitative trait linkage analysis: pleiotropy versus co-incident linkages. Genet Epidemiol 1997; 14: 953-958
    • (1997) Genet Epidemiol , vol.14 , pp. 953-958
    • Almasy, L.1    Dyer, T.D.2    Blangero, J.3
  • 45
    • 24044550689 scopus 로고    scopus 로고
    • PEDSTATS: Descriptive statistics, graphics and quality assessment for gene mapping data
    • Wigginton JE, Abecasis GR: PEDSTATS: descriptive statistics, graphics and quality assessment for gene mapping data. Bioinformatics 2005; 21: 3445-3447
    • (2005) Bioinformatics , vol.21 , pp. 3445-3447
    • Wigginton, J.E.1    Abecasis, G.R.2
  • 46
    • 0023181001 scopus 로고
    • Robust inference for variance components models in families ascertained through probands: I. Conditioning on proband's phenotype
    • Beaty TH, Liang KY: Robust inference for variance components models in families ascertained through probands: I. Conditioning on proband's phenotype. Genet Epidemiol 1987; 4: 203-210
    • (1987) Genet Epidemiol , vol.4 , pp. 203-210
    • Beaty, T.H.1    Liang, K.Y.2
  • 47
    • 0033820011 scopus 로고    scopus 로고
    • Robust LOD scores for variance component-based linkage analysis
    • Blangero J, Williams JT, Almasy L: Robust LOD scores for variance component-based linkage analysis. Genet Epidemiol 2000; 19(Suppl 1):S8-S14
    • (2000) Genet Epidemiol , vol.19 , Issue.SUPPL. 1
    • Blangero, J.1    Williams, J.T.2    Almasy, L.3
  • 48
    • 0036077215 scopus 로고    scopus 로고
    • Powerful regressionbased quantitative-trait linkage analysis of general pedigrees
    • Sham PC, Purcell S, Cherny SS, Abecasis GR: Powerful regressionbased quantitative-trait linkage analysis of general pedigrees. Am J Hum Genet 2002; 71: 238-253
    • (2002) Am J Hum Genet , vol.71 , pp. 238-253
    • Sham, P.C.1    Purcell, S.2    Cherny, S.S.3    Abecasis, G.R.4
  • 49
    • 0842307344 scopus 로고    scopus 로고
    • Inherent bias toward the null hypothesis in conventional multipoint nonparametric linkage analysis
    • Schork NJ, Greenwood TA: Inherent bias toward the null hypothesis in conventional multipoint nonparametric linkage analysis. Am J Hum Genet 2004; 74: 306-316
    • (2004) Am J Hum Genet , vol.74 , pp. 306-316
    • Schork, N.J.1    Greenwood, T.A.2
  • 51
    • 0028877463 scopus 로고
    • Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
    • Lander E, Kruglyak L: Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 1995; 11: 241-247
    • (1995) Nat Genet , vol.11 , pp. 241-247
    • Lander, E.1    Kruglyak, L.2
  • 52
    • 0031714729 scopus 로고    scopus 로고
    • Molecular and clinical studies in SCA-7 define a broad clinical spectrum and the infantile phenotype
    • Benton CS, de Silva R, Rutledge SL, Bohlega S, Ashizawa T, Zoghbi HY: Molecular and clinical studies in SCA-7 define a broad clinical spectrum and the infantile phenotype. Neurology 1998; 51: 1081-1086
    • (1998) Neurology , vol.51 , pp. 1081-1086
    • Benton, C.S.1    De Silva, R.2    Rutledge, S.L.3    Bohlega, S.4    Ashizawa, T.5    Zoghbi, H.Y.6
  • 54
    • 0032718877 scopus 로고    scopus 로고
    • Possible association between schizophrenia and a CAG repeat polymorphism in the spinocerebellar ataxia type 1 (SCA1) gene on human chromosome 6p23
    • Joo EJ, Lee JH, Cannon TD, Price RA: Possible association between schizophrenia and a CAG repeat polymorphism in the spinocerebellar ataxia type 1 (SCA1) gene on human chromosome 6p23. Psychiatr Genet 1999; 9: 7-11
    • (1999) Psychiatr Genet , vol.9 , pp. 7-11
    • Joo, E.J.1    Lee, J.H.2    Cannon, T.D.3    Price, R.A.4
  • 57
    • 68449086236 scopus 로고    scopus 로고
    • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
    • International Schizophrenia Consortium
    • Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC, Sullivan PF, Sklar P; International Schizophrenia Consortium: Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 2009; 460: 748-752
    • (2009) Nature , vol.460 , pp. 748-752
    • Purcell, S.M.1    Wray, N.R.2    Stone, J.L.3    Visscher, P.M.4    O'Donovan, M.C.5    Sullivan, P.F.6    Sklar, P.7
  • 59
    • 80051953863 scopus 로고    scopus 로고
    • Association analysis of 94 candidate genes and schizophreniarelated endophenotypes
    • Greenwood TA, Light GA, Swerdlow NR, Radant AD, Braff DL: Association analysis of 94 candidate genes and schizophreniarelated endophenotypes. PLoS ONE 2011; 168: 930-946
    • (2011) PLoS ONE , vol.168 , pp. 930-946
    • Greenwood, T.A.1    Light, G.A.2    Swerdlow, N.R.3    Radant, A.D.4    Braff, D.L.5
  • 60
    • 33750069150 scopus 로고    scopus 로고
    • Family-based study of markers at the 5:-flanking region of the human dopamine transporter gene reveals potential association with schizophrenic psychoses
    • Stöber G, Sprandel J, Jabs B, Pfuhlmann B, Möller-Ehrlich K, Knapp M: Family-based study of markers at the 5:-flanking region of the human dopamine transporter gene reveals potential association with schizophrenic psychoses. Eur Arch Psychiatry Clin Neurosci 2006; 256: 422-427
    • (2006) Eur Arch Psychiatry Clin Neurosci , vol.256 , pp. 422-427
    • Stöber, G.1    Sprandel, J.2    Jabs, B.3    Pfuhlmann, B.4    Möller-Ehrlich, K.5    Knapp, M.6
  • 61
    • 0035143189 scopus 로고    scopus 로고
    • Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: Differential effects of D1 and D2 receptor antagonists
    • Ralph RJ, Paulus MP, Fumagalli F, Caron MG, Geyer MA: Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: differential effects of D1 and D2 receptor antagonists. J Neurosci 2001; 21: 305-313
    • (2001) J Neurosci , vol.21 , pp. 305-313
    • Ralph, R.J.1    Paulus, M.P.2    Fumagalli, F.3    Caron, M.G.4    Geyer, M.A.5
  • 63
    • 33846194535 scopus 로고    scopus 로고
    • Association study between the NMDA receptor 2B subunit gene (GRIN2B) and schizophrenia: A HuGE review and meta-analysis
    • Li D, He L: Association study between the NMDA receptor 2B subunit gene (GRIN2B) and schizophrenia: a HuGE review and meta-analysis. Genet Med 2007; 9: 4-8
    • (2007) Genet Med , vol.9 , pp. 4-8
    • Li, D.1    He, L.2
  • 69
  • 79
    • 44149113011 scopus 로고    scopus 로고
    • Candidate genes and the behavioral phenotype in 22q11.2 deletion syndrome
    • Prasad SE, Howley S, Murphy KC: Candidate genes and the behavioral phenotype in 22q11.2 deletion syndrome. Dev Disabil Res Rev 2008; 14: 26-34
    • (2008) Dev Disabil Res Rev , vol.14 , pp. 26-34
    • Prasad, S.E.1    Howley, S.2    Murphy, K.C.3
  • 80
    • 0036258079 scopus 로고    scopus 로고
    • Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia
    • Badner JA, Gershon ES: Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia. Mol Psychiatry 2002; 7: 405-411
    • (2002) Mol Psychiatry , vol.7 , pp. 405-411
    • Badner, J.A.1    Gershon, E.S.2
  • 82
    • 51649107017 scopus 로고    scopus 로고
    • Rare chromosomal deletions and duplications increase risk of schizophrenia
    • International Schizophrenia Consortium
    • International Schizophrenia Consortium: Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature 2008; 455: 237-241
    • (2008) Nature , vol.455 , pp. 237-241
  • 84
    • 64549147485 scopus 로고    scopus 로고
    • Wellcome trust case control consortium: Support for the involvement of large copy number variants in the pathogenesis of schizophrenia
    • International Schizophrenia Consortium
    • Kirov G, Grozeva D, Norton N, Ivanov D, Mantripragada KK, Holmans P, Craddock N, Owen MJ, O'Donovan MC; International Schizophrenia Consortium; Wellcome Trust Case Control Consortium: Support for the involvement of large copy number variants in the pathogenesis of schizophrenia. Hum Mol Genet 2009; 18: 1497-1503
    • (2009) Hum Mol Genet , vol.18 , pp. 1497-1503
    • Kirov, G.1    Grozeva, D.2    Norton, N.3    Ivanov, D.4    Mantripragada, K.K.5    Holmans, P.6    Craddock, N.7    Owen, M.J.8    O'Donovan, M.C.9
  • 86
    • 80053384370 scopus 로고    scopus 로고
    • Genome-wide association study identifies five new schizophrenia loci
    • Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium
    • Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium: Genome-wide association study identifies five new schizophrenia loci. Nat Genet 2011; 43: 969-976
    • (2011) Nat Genet , vol.43 , pp. 969-976
  • 88
    • 79955841697 scopus 로고    scopus 로고
    • Evaluating the heritability explained by known susceptibility variants: A survey of ten complex diseases
    • So HC, Gui AH, Cherny SS, Sham PC: Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases. Genet Epidemiol 2011; 35: 310-317
    • (2011) Genet Epidemiol , vol.35 , pp. 310-317
    • So, H.C.1    Gui, A.H.2    Cherny, S.S.3    Sham, P.C.4
  • 89
    • 33846525474 scopus 로고    scopus 로고
    • The endophenotype concept in psychiatric genetics
    • Flint J, Munafò MR: The endophenotype concept in psychiatric genetics. Psychol Med 2007; 37: 163-180
    • (2007) Psychol Med , vol.37 , pp. 163-180
    • Flint, J.1    Munafò, M.R.2
  • 90
    • 79952265020 scopus 로고    scopus 로고
    • Integrative circuit models and their implications for the pathophysiologies and treatments of the schizophrenias. The Behavioral Neurobiology of Schizophrenia and its Treatment
    • Edited by Geyer MA, Ellenbroek BA, Marsden CA. New York, Springer
    • Swerdlow NR: Integrative circuit models and their implications for the pathophysiologies and treatments of the schizophrenias. The Behavioral Neurobiology of Schizophrenia and its Treatment, in Current Topics in Behavioral Neuroscience. Edited by Geyer MA, Ellenbroek BA, Marsden CA. New York, Springer, 2010, pp 555-586
    • (2010) Current Topics in Behavioral Neuroscience , pp. 555-586
    • Swerdlow, N.R.1
  • 91
    • 0034927844 scopus 로고    scopus 로고
    • Neural circuit regulation of prepulse inhibition of startle in the rat: Current knowledge and future challenges
    • Swerdlow NR, Geyer MA, Braff DL: Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges. Psychopharmacology (Berl) 2001; 156: 194-215
    • (2001) Psychopharmacology (Berl) , vol.156 , pp. 194-215
    • Swerdlow, N.R.1    Geyer, M.A.2    Braff, D.L.3
  • 92
    • 84925614879 scopus 로고    scopus 로고
    • Promises and challenges of translational research in neuropsychiatry
    • Edited by Barrett JE, Coyle JT, Williams M. New York, Cambridge University Press
    • Braff DL: Promises and Challenges of Translational Research in Neuropsychiatry, in Translational Neuroscience: Applications in Neurology, Psychiatry, and Neurodevelopmental Disorders. Edited by Barrett JE, Coyle JT, Williams M. New York, Cambridge University Press, 2012, pp 339-358
    • (2012) Translational Neuroscience: Applications in Neurology, Psychiatry, and Neurodevelopmental Disorders , pp. 339-358
    • Braff, D.L.1


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