Dynamics and ethics of comprehensive preimplantation genetic testing: A review of the challenges

Human Reproduction Update

Volumn 19, Issue 4, 2013, Pages 366-375

  Hens, Kristien ^a,b   Dondorp, Wybo ^a   Handyside, Alan H ^c,d   Harper, Joyce ^e,f   Newson, Ainsley J ^g   Pennings, Guido ^h   Rehmann Sutter, Christoph ⁱ   de Wert, Guido ^a,b  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b CSG Centre for Society and the Life Sciences   (Netherlands)

^c London Bridge Fertility   (United Kingdom)

^d UNIVERSITY OF LEEDS   (United Kingdom)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

^f Centre for Reproductive and Genetic Health   (United Kingdom)

^g UNIVERSITY OF SYDNEY   (Australia)

^h GHENT UNIVERSITY   (Belgium)

ⁱ UNIVERSITY OF LÜBECK   (Germany)

Author keywords

Comprehensive screening; Embryos; Ethics; Microarrays; Preimplantation genetic diagnosis; Preimplantation genetic screening; Whole genome sequencing

Indexed keywords

ANEUPLOIDY; ARTICLE; BENEFICENCE; BLASTOCYST; BLASTOMA; CHILDHOOD DISEASE; CHROMOSOME ABERRATION; CHROMOSOME TRANSLOCATION; COPY NUMBER VARIATION; EMBRYO TRANSFER; EMBRYOLOGY; FERTILIZATION IN VITRO; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE SEQUENCE; GENETIC RISK; GENETIC SCREENING; GENETIC VARIABILITY; GENOME; GENOME ANALYSIS; GENOTYPE; HETEROZYGOTE; HETEROZYGOTE DETECTION; HIGH THROUGHPUT SEQUENCING; HUMAN; INFORMED CONSENT; MASS SCREENING; MATERNAL AGE; MEDICAL ETHICS; MOSAICISM; NETHERLANDS; PATIENT DECISION MAKING; POLAR BODY; POLYMERASE CHAIN REACTION; PREGNANCY RATE; PREIMPLANTATION EMBRYO; PRENATAL DIAGNOSIS; PRENATAL SCREENING; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SINGLE NUCLEOTIDE POLYMORPHISM; STEATOCYSTOMA MULTIPLEX;

COMPREHENSIVE SCREENING; EMBRYOS; ETHICS; MICROARRAYS; PREIMPLANTATION GENETIC DIAGNOSIS; PREIMPLANTATION GENETIC SCREENING; WHOLE GENOME SEQUENCING;

BLASTOCYST; BLASTOMERES; CLEAVAGE STAGE, OVUM; FEMALE; FERTILIZATION IN VITRO; HUMANS; MALE; NETHERLANDS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PREIMPLANTATION DIAGNOSIS;

EID: 84879442717     PISSN: 13554786     EISSN: 14602369     Source Type: Journal    
DOI: 10.1093/humupd/dmt009     Document Type: Article

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