Paeonol inhibits hepatic fibrogenesis via disrupting nuclear factor-κB pathway in activated stellate cells: In vivo and in vitro studies

Journal of Gastroenterology and Hepatology (Australia)

Volumn 28, Issue 7, 2013, Pages 1223-1233

  Kong, Desong ^a   Zhang, Feng ^a   Wei, Donghua ^b   Zhu, Xiaojing ^a   Zhang, Xiaoping ^a   Chen, Li ^a   Lu, Yin ^a   Zheng, Shizhong ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Hepatic fibrosis; Hepatic stellate cell; Mitochondrial apoptosis; NF B; Paeonol

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ALANINE AMINOTRANSFERASE; ALPHA SMOOTH MUSCLE ACTIN; ASPARTATE AMINOTRANSFERASE; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 2; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LACTATE DEHYDROGENASE; MESSENGER RNA; PEONOL; PROPIDIUM IODIDE; TRANSCRIPTION FACTOR RELA; TRYPAN BLUE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIFIBROGENIC ACTIVITY; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELL ACTIVATION; CELL ASSAY; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG DOSE COMPARISON; DRUG MECHANISM; ENZYME PHOSPHORYLATION; ENZYME RELEASE; FIBROGENESIS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HISTOPATHOLOGY; IMMUNOFLUORESCENCE; IN VITRO STUDY; IN VIVO STUDY; LIVER FIBROSIS; LIVER INJURY; LIVER PROTECTION; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; STELLATE CELL; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

EID: 84879427704     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/jgh.12147     Document Type: Article

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