Synthesis and on-target antibacterial activity of novel 3-elongated arylalkoxybenzamide derivatives as inhibitors of the bacterial cell division protein FtsZ

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 14, 2013, Pages 4076-4079

  Ma, Shutao ^a   Ma, Siti ^a   Cong, Chao ^a   Meng, Xiaohui ^a   Cao, Shasha ^a   Yang, Hongkun ^a   Guo, Yuanyuan ^a   Lu, Xueyi ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Antibacterial activity; Arylalkoxybenzamide; FtsZ inhibitors; Synthesis Cell division inhibition activity

Indexed keywords

3 ELONGATED ARYLALKOXYBENZAMIDE DERIVATIVE; 3 HETEROARYLALKYLOXYBENZAMIDE DERIVATIVE; 3 HETEROARYLTHIOALKYLOXYBENZAMIDE DERIVATIVE; 3 PHENOXYAKLYLOXYBENZAMIDE DERIVATIVE; ANTIINFECTIVE AGENT; BENZAMIDE DERIVATIVE; FTSZ PROTEIN; UNCLASSIFIED DRUG;

ALKYLATION; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC SENSITIVITY; ARTICLE; BACILLUS SUBTILIS; CELL DIVISION; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; NONHUMAN; STAPHYLOCOCCUS AUREUS;

ANTI-BACTERIAL AGENTS; BACILLUS SUBTILIS; BACTERIAL PROTEINS; BENZAMIDES; CYTOSKELETAL PROTEINS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; STAPHYLOCOCCUS AUREUS;

BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS AUREUS;

EID: 84879418533     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.05.056     Document Type: Article

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