Apolipoprotein A-I inhibits LPS-induced atherosclerosis in ApoE -/- mice possibly via activated STAT3-mediated upregulation of tristetraprolin

Acta Pharmacologica Sinica

Volumn 34, Issue 6, 2013, Pages 837-846

  Yin, Kai ^a   Tang, Shi Lin ^a   Yu, Xiao Hua ^a   Tu, Guang Hui ^b   He, Rong Fang ^a   Li, Jin Feng ^a   Xie, Di ^a   Gui, Qing Jun ^a   Fu, Yu Chang ^c   Jiang, Zhi Sheng ^a   Tu, Jian ^a   Tang, Chao Ke ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

^b Department of Pathology   (China)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

ApoE mice; apolipoprotein A I; atherosclerosis; cytokines; heart; inflammation; JAK2 STAT3 signaling pathway; lipopolysaccharide; macrophage; tristetraprolin

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN E; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERLEUKIN 1BETA; INTERLEUKIN 6; JANUS KINASE 2; LIPOPOLYSACCHARIDE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; STAT3 PROTEIN; TRISTETRAPROLIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATHEROSCLEROSIS; CELL INFILTRATION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; EX VIVO STUDY; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; MALE; MOUSE; NONHUMAN; PERITONEAL CAVITY; PERITONEUM MACROPHAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; APOLIPOPROTEIN A-I; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CYTOKINES; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; STAT3 TRANSCRIPTION FACTOR; TRISTETRAPROLIN; UP-REGULATION;

EID: 84879390731     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2013.10     Document Type: Article

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