Serotonin hyperinnervation abolishes seizure susceptibility in Otx2 conditional mutant mice

Journal of Neuroscience

Volumn 28, Issue 37, 2008, Pages 9271-9276

  Tripathi, Prem Prakash ^a,b   Di Giovannantonio, Luca Giovanni ^c,d   Viegi, Alessandro ^a,b   Wurst, Wolfgang ^e,f   Simeone, Antonio ^c,d   Bozzi, Yuri ^a  

^a CNR   (Italy)

^b SCUOLA NORMALE SUPERIORE   (Italy)

^c CEINGE BIOTECNOLOGIE AVANZATE   (Italy)

^d INSTITUTE OF GENETICS AND BIOPHYSICS ADRIANO BUZZATI TRAVERSO   (Italy)

^e INSTITUTE OF EPIDEMIOLOGY   (Germany)

^f MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

Author keywords

Epilepsy; Hippocampus; Kainic acid; pCPA; Seizures; Serotonin transporter

Indexed keywords

CRE RECOMBINASE; FENCLONINE; KAINIC ACID; MESSENGER RNA; SEROTONIN; SEROTONIN TRANSPORTER; TRANSCRIPTION FACTOR OTX2; EN1 PROTEIN, MOUSE; ENZYME INHIBITOR; HOMEODOMAIN PROTEIN; PROTEIN C FOS; TRANSCRIPTION FACTOR OTX;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; ENGRAILED1 GENE; FEMALE; GENE; GENE INACTIVATION; GRAND MAL SEIZURE; HIPPOCAMPUS; MALE; MESENCEPHALON; MOUSE; MOUSE MUTANT; NONHUMAN; ONCOGENE C FOS; PONS; PRIORITY JOURNAL; SEIZURE SUSCEPTIBILITY; SEROTONIN BRAIN LEVEL; SEROTONINERGIC NERVE CELL; ANALYSIS OF VARIANCE; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUTATION; SEIZURE; TIME; TRANSGENIC MOUSE;

ANALYSIS OF VARIANCE; ANIMALS; ENZYME INHIBITORS; FENCLONINE; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HOMEODOMAIN PROTEINS; KAINIC ACID; MESENCEPHALON; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; OTX TRANSCRIPTION FACTORS; PROTO-ONCOGENE PROTEINS C-FOS; RNA, MESSENGER; SEIZURES; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; TIME FACTORS;

EID: 55249117575     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2208-08.2008     Document Type: Article

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