Failure of fibrotic liver regeneration in mice is linked to a severe fibrogenic response driven by hepatic progenitor cell activation

American Journal of Pathology

Volumn 183, Issue 1, 2013, Pages 182-194

  Kuramitsu, Kaori ^a   Sverdlov, Deanna Y ^a   Liu, Susan B ^a   Csizmadia, Eva ^a   Burkly, Linda ^b   Schuppan, Detlef ^a   Hanto, Douglas W ^a   Otterbein, Leo E ^a   Popov, Yury ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BIOGEN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; CARBON TETRACHLORIDE; MEMBRANE PROTEIN; MESSENGER RNA; NEUTRALIZING ANTIBODY; TUMOR NECROSIS FACTOR LIKE WEAK INDUCER OF APOPTOSIS; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL COMPARTMENTALIZATION; CELL DEATH; CELL DIVISION; CELL EXPANSION; CELL PROLIFERATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; HISTOPATHOLOGY; LIVER CELL; LIVER FIBROSIS; LIVER FUNCTION; LIVER REGENERATION; MALE; MOUSE; NONHUMAN; PARTIAL HEPATECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; SURVIVAL;

ALANINE TRANSAMINASE; ANIMALS; BIOLOGICAL MARKERS; CELL DEATH; COLLAGEN; FLUORESCENT ANTIBODY TECHNIQUE; HEPATECTOMY; KAPLAN-MEIER ESTIMATE; LIVER; LIVER CIRRHOSIS; LIVER REGENERATION; MALE; MICE; MICE, INBRED C57BL; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84879384652     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2013.03.018     Document Type: Article

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