메뉴 건너뛰기




Volumn 51, Issue 7, 2013, Pages 836-843

Protective effects of saffron (Crocus sativus) against lethal ventricular arrhythmias induced by heart reperfusion in rat: A potential anti-arrhythmic agent

Author keywords

Heart; Ischemia reperfusion; Ventricular fibrillation; Ventricular tachycardia

Indexed keywords

AMIODARONE; CROCUS SATIVUS EXTRACT;

EID: 84879361441     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2013.767362     Document Type: Article
Times cited : (37)

References (45)
  • 1
    • 69949085143 scopus 로고    scopus 로고
    • Dose-related shortening of ventricular tachycardia cycle length after administration of the KATP channel opener bimakalim in a 4-day-old chronic infarct anesthetized pig model
    • Aidonidis I, Poyatzi A, Stamatiou G, et al. (2009). Dose-related shortening of ventricular tachycardia cycle length after administration of the KATP channel opener bimakalim in a 4-day-old chronic infarct anesthetized pig model. J Cardiovasc Pharmacol Ther 14:222-30
    • (2009) J Cardiovasc Pharmacol Ther , vol.14 , pp. 222-230
    • Aidonidis, I.1    Poyatzi, A.2    Stamatiou, G.3
  • 2
    • 77952881985 scopus 로고    scopus 로고
    • Potential of crocus sativus (saffron) and its constituent, crocin, as hypolipidemic and antioxidant in rats
    • Asdaq SMB, Inamdar MN. (2010). Potential of Crocus sativus (saffron) and its constituent, crocin, as hypolipidemic and antioxidant in rats. Appl Biochem Biotechnol 163:358-72
    • (2010) Appl Biochem Biotechnol , vol.163 , pp. 358-372
    • Asdaq, S.M.B.1    Inamdar, M.N.2
  • 3
    • 70849107959 scopus 로고    scopus 로고
    • Redox-modification of ryanodine receptors underlies calcium alternans in a canine model of sudden cardiac death
    • Belevych AE, Terentyev D, Viatchenko-Karpinski S, et al. (2009). Redox-modification of ryanodine receptors underlies calcium alternans in a canine model of sudden cardiac death. Cardiovas Res 84:387-95
    • (2009) Cardiovas Res , vol.84 , pp. 387-395
    • Belevych, A.E.1    Terentyev, D.2    Viatchenko-Karpinski, S.3
  • 4
    • 51849154149 scopus 로고    scopus 로고
    • The cardiac sarcolemmal ATP-sensitive potassium channel as a novel target for anti-Arrhythmic therapy
    • Billman GE. (2008). The cardiac sarcolemmal ATP-sensitive potassium channel as a novel target for anti-Arrhythmic therapy. Pharmacol Ther 120:54-70
    • (2008) Pharmacol Ther , vol.120 , pp. 54-70
    • Billman, G.E.1
  • 5
    • 1642374380 scopus 로고    scopus 로고
    • Effects of a Novel Cardioselective ATP-Sensitive Potassium Channel Antagonist, 1-[[5-[2-(5-Chloro-o-anisamido)ethyl]-β -methoxyethoxyphenyl] sulfonyl]-3-methylthiourea, Sodium Salt (HMR 1402), on Susceptibility to Ventricular Fibrillation Induced by Myocardial Ischemia: In Vitro and in Vivo Studies
    • DOI 10.1124/jpet.103.061416
    • Billman GE, Houle MS, Englert HC, Gogelein H. (2004). Effects of a novel cardioselective ATP-sensitive potassium channel antagonist, 1-[[5-[2-(5-chloro- o-Anisamido)ethyl]-beta-methoxyethoxyphenyl]sulfonyl]-3-methylthiourea, sodium salt (HMR 1402), on susceptibility to ventricular fibrillation induced by myocardial ischemia: In vitro and in vivo studies. J Pharmacol Exp Ther 309:182-92 (Pubitemid 38393129)
    • (2004) Journal of Pharmacology and Experimental Therapeutics , vol.309 , Issue.1 , pp. 182-192
    • Billman, G.E.1    Houle, M.S.2    Englert, H.C.3    Gogelein, H.4
  • 7
    • 40849102570 scopus 로고    scopus 로고
    • Effect of aqueous-ethanol extract from Crocus sativus (saffron) on guinea-pig isolated heart
    • DOI 10.1002/ptr.2317
    • Boskabady MH, Shafei MN, Shakiba A, Sang Sefidi H. (2008). Effect of aqueous-ethanol extract from Crocus sativus (saffron) on Guinea-pig isolated heart. Phytother Res 22:330-34 (Pubitemid 351397434)
    • (2008) Phytotherapy Research , vol.22 , Issue.3 , pp. 330-334
    • Boskabady, M.H.1    Shafei, M.N.2    Shakiba, A.3    Sang Sefidi, H.4
  • 8
    • 77956597409 scopus 로고    scopus 로고
    • Cardiac mitochondria and arrhythmias
    • Brown DA, ÓRourke B. (2010). Cardiac mitochondria and arrhythmias. Cardiovasc Res 88:241-9
    • (2010) Cardiovasc Res , vol.88 , pp. 241-249
    • Brown, D.A.1    ÓRourke, B.2
  • 9
    • 0022501474 scopus 로고
    • Reperfusion arrhythmias during coronary reperfusion therapy in man. Clinical and angiographic correlations
    • Buckingham TA, Devine JE, Redd RM, Kennedy HL. (1986). Reperfusion arrhythmias during coronary reperfusion therapy in man. Clinical and angiographic correlations. Chest 90:346-51 (Pubitemid 16014367)
    • (1986) Chest , vol.90 , Issue.3 , pp. 346-351
    • Buckingham, R.A.1    Devine, J.E.2    Redd, R.M.3    Kennedy, H.L.4
  • 12
    • 34247209532 scopus 로고    scopus 로고
    • Potent mitochondria-targeted peptides reduce myocardial infarction in rats
    • DOI 10.1097/01.mca.0000236285.71683.b6, PII 0001950120070500000011
    • Cho J, Won K, Wu D, et al. (2007). Potent mitochondria-Targeted peptides reduce myocardial infarction in rats. Coron Artery Dis 18:215-20 (Pubitemid 46608500)
    • (2007) Coronary Artery Disease , vol.18 , Issue.3 , pp. 215-220
    • Cho, J.1    Won, K.2    Wu, D.3    Soong, Y.4    Liu, S.5    Szeto, H.H.6    Hong, M.K.7
  • 13
    • 0026742636 scopus 로고
    • Reperfusion arrhythmias in isolated perfused pig hearts: Inhomogeneities in extracellular potassium, ST and TQ potentials, and transmembrane action potentials
    • Coronel R, Wilms-Schopman FJG, Opthof T, et al. (1992). Reperfusion arrhythmias in isolated perfused pig hearts: Inhomogeneities in extracellular potassium, ST and TQ potentials, and transmembrane action potentials. Circ Res 71:1131-42
    • (1992) Circ Res , vol.71 , pp. 1131-1142
    • Coronel, R.1    Wilms-Schopman, F.J.G.2    Opthof, T.3
  • 14
    • 18044366583 scopus 로고    scopus 로고
    • Pretreatment with pinacidil promotes arrhythmias in an isolated tissue model of cardiac ischemia and reperfusion
    • DOI 10.1124/jpet.104.081349
    • Ferrier GR, Howlett SE. (2005). Pretreatment with pinacidil promotes arrhythmias in an isolated tissue model of cardiac ischemia and reperfusion. J Pharmacol Exp Ther 313:823-30 (Pubitemid 40604184)
    • (2005) Journal of Pharmacology and Experimental Therapeutics , vol.313 , Issue.2 , pp. 823-830
    • Ferrier, G.R.1    Howlett, S.E.2
  • 15
    • 75249099832 scopus 로고    scopus 로고
    • Preventive effect of crocin of Crocus sativus on hemodynamic, biochemical, histopathological and ultrastuctural alterations in isoproterenol-induced cardiotoxicity in rats
    • Goyal SN, Arora S, Sharma AK, et al. (2010). Preventive effect of crocin of Crocus sativus on hemodynamic, biochemical, histopathological and ultrastuctural alterations in isoproterenol-induced cardiotoxicity in rats. Phytomedicine 17:227-32
    • (2010) Phytomedicine , vol.17 , pp. 227-232
    • Goyal, S.N.1    Arora, S.2    Sharma, A.K.3
  • 16
    • 34249330240 scopus 로고    scopus 로고
    • Current concepts in the mechanisms and management of drug-induced QT prolongation and torsade de pointes
    • DOI 10.1016/j.ahj.2007.01.040, PII S0002870307003262
    • Gupta A, Lawrence AT, Krishnan K, et al. (2007). Current concepts in the mechanisms and management of drug-induced QT prolongation and torsade de pointes. Am Heart J 153:891-9 (Pubitemid 46809861)
    • (2007) American Heart Journal , vol.153 , Issue.6 , pp. 891-899
    • Gupta, A.1    Lawrence, A.T.2    Krishnan, K.3    Kavinsky, C.J.4    Trohman, R.G.5
  • 17
    • 34247878303 scopus 로고    scopus 로고
    • Antioxidants decrease reperfusion induced arrhythmias in myocardial infarction with ST-elevation
    • Hicks JJ, Montes-Cortes DH, Cruz-Dominguez MP, et al. (2007). Antioxidants decrease reperfusion induced arrhythmias in myocardial infarction with ST-elevation. Front Biosci 12:2029-37
    • (2007) Front Biosci , vol.12 , pp. 2029-2037
    • Hicks, J.J.1    Montes-Cortes, D.H.2    Cruz-Dominguez, M.P.3
  • 18
    • 68849096206 scopus 로고    scopus 로고
    • Crocus sativus L (saffron) extract and its active constituents (crocin and safranal) on ischemia-reperfusion in rat skeletal muscle
    • Hosseinzadeh H, Modaghegh MH, Saffari Z. (2009). Crocus sativus L. (saffron) extract and its active constituents (crocin and safranal) on ischemia-reperfusion in rat skeletal muscle. Evid-Based Complement Alternat Med 6:343-50
    • (2009) Evid-Based Complement Alternat Med , vol.6 , pp. 343-350
    • Hosseinzadeh, H.1    Modaghegh, M.H.2    Saffari, Z.3
  • 19
    • 27444437828 scopus 로고    scopus 로고
    • Protective effect of aqueous saffron extract (Crocus sativus L.) and crocin, its active constituent, on renal ischemia-reperfusion-induced oxidative damage in rats
    • Hosseinzadeh H, Sadeghnia HR, Ziaee T, Danaee A. (2005). Protective effect of aqueous saffron extract (Crocus sativus L.) and crocin, its active constituent, on renal ischemia-reperfusion-induced oxidative damage in rats. J Pharm Pharm Sci 8:387-93 (Pubitemid 41529317)
    • (2005) Journal of Pharmacy and Pharmaceutical Sciences , vol.8 , Issue.3 , pp. 387-393
    • Hosseinzadeh, H.1    Sadeghnia, H.R.2    Ziaee, T.3    Danaee, A.4
  • 20
    • 0002569627 scopus 로고
    • The effect of acute ischaemia on transmembrane potentials in the intact heart: The relation to reentrant mechanisms
    • Kulbertus HE, ed. Baltimore (MD): University Park Press
    • Janse MJ, Downar E. (1977). The effect of acute ischaemia on transmembrane potentials in the intact heart: The relation to reentrant mechanisms. In: Kulbertus HE, ed. Reentrant Arrhythmias, Mechanisms and Treatment. Baltimore (MD): University Park Press, 195-209
    • (1977) Reentrant Arrhythmias, Mechanisms and Treatment , pp. 195-209
    • Janse, M.J.1    Downar, E.2
  • 21
    • 84867606330 scopus 로고    scopus 로고
    • Electrocardiogram alterations following one-week consumption of Crocus sativus L saffron
    • Joukar S. (2012). Electrocardiogram alterations following one-week consumption of Crocus sativus L. (saffron). EXCLI J 11:480-6
    • (2012) EXCLI J , vol.11 , pp. 480-486
    • Joukar, S.1
  • 22
    • 77951140139 scopus 로고    scopus 로고
    • The effect of saffron consumption on biochemical and histopathological heart indices of rats with myocardial infarction
    • Joukar S, Najafipour H, Khaksari M, et al. (2010). The effect of saffron consumption on biochemical and histopathological heart indices of rats with myocardial infarction. Cardiovas Toxicol 10:66-71
    • (2010) Cardiovas Toxicol , vol.10 , pp. 66-71
    • Joukar, S.1    Najafipour, H.2    Khaksari, M.3
  • 23
    • 84867625734 scopus 로고    scopus 로고
    • Ameliorative effect of black tea on nicotine induced cardiovascular pathogenesis in rat
    • Joukar S, Shahouzehi B. Najafipour H., et al. (2012). Ameliorative effect of black tea on nicotine induced cardiovascular pathogenesis in rat. EXCLI J 11:309-17
    • (2012) EXCLI J , vol.11 , pp. 309-317
    • Joukar, S.1    Shahouzehi, B.2    Najafipour, H.3
  • 24
    • 0021682528 scopus 로고
    • Delayed afterdepolarizations and triggered activity induced in feline Purkinje fibers by α-adrenergic stimulation in the presence of elevated calcium levels
    • Kimura S, Cameron JS, Kozlovskis PL, et al. (1984). Delayed after depolarizations and triggered activity induced in feline Purkinje fibers by adrenergic stimulation in the presence of elevated calcium levels. Circulation 70:1074-82 (Pubitemid 15219369)
    • (1984) Circulation , vol.70 , Issue.6 , pp. 1074-1082
    • Kimura, S.1    Cameron, J.S.2    Kozlovskis, P.L.3
  • 25
    • 84861813693 scopus 로고    scopus 로고
    • Frequency-dependent electrophysiological remodeling of the AV Node by hydroalcohol extract of Crocus sativus L saffron) during experimental atrial fibrillation: The role of endogenous nitric oxide
    • Khori V, Alizadeh AM, Yazdi H, et al. (2011). Frequency-dependent electrophysiological remodeling of the AV Node by hydroalcohol extract of Crocus sativus L. (saffron) during experimental atrial fibrillation: The role of endogenous nitric oxide. Phytother Res 26:826-2
    • (2011) Phytother Res , vol.26 , pp. 826-832
    • Khori, V.1    Alizadeh, A.M.2    Yazdi, H.3
  • 26
    • 77954090017 scopus 로고    scopus 로고
    • Heart rate correction of the QT duration in rats
    • Kmecova J, Klimas J. (2010). Heart rate correction of the QT duration in rats. Eur J Pharmacol 641:187-92
    • (2010) Eur J Pharmacol , vol.641 , pp. 187-192
    • Kmecova, J.1    Klimas, J.2
  • 27
    • 0026783121 scopus 로고
    • The effect of superoxide dismutase in the myocardium during reperfusion in the dog
    • Konya L, Kekesi V, Juhasz-Nagy S, Feher J. (1992). The effect of superoxide dismutase in the myocardium during reperfusion in the dog. Free Radic Biol Med 13:527-32
    • (1992) Free Radic Biol Med , vol.13 , pp. 527-532
    • Konya, L.1    Kekesi, V.2    Juhasz-Nagy, S.3    Feher, J.4
  • 28
    • 77955769028 scopus 로고    scopus 로고
    • Differential effects of four xylidine derivatives in the model of ischemia-And re-perfusion-induced arrhythmias in rats in vivo
    • Krzemin'ski TF, Mitrega K, Zorniak M, Porc M. (2010). Differential effects of four xylidine derivatives in the model of ischemia-And re-perfusion-induced arrhythmias in rats in vivo. Eur J Pharmacol 644:120-7
    • (2010) Eur J Pharmacol , vol.644 , pp. 120-127
    • Krzemin'ski, T.F.1    Mitrega, K.2    Zorniak, M.3    Porc, M.4
  • 30
    • 0023940199 scopus 로고
    • Reperfusion-induced arrhythmias: A study of the role of xanthine oxidase-derived free radicals in the rat heart
    • Manning A, Bernier M, Crome R, et al. (1988). Reperfusion-induced arrhythmias: A study of the role of xanthine oxidase-derived free radicals in the rat heart. J Mol Cell Cardiol 20:35-45
    • (1988) J Mol Cell Cardiol , vol.20 , pp. 35-45
    • Manning, A.1    Bernier, M.2    Crome, R.3
  • 31
    • 0025195094 scopus 로고
    • 2+](i) in perfused hearts. Critical evaluation of the 5F-BAPTA and nuclear magnetic resonance method as applied to the study of ischemia and reperfusion
    • Marban E, Kitakaze M, Koretsune Y, et al. (1990). Quantification of [Ca2]i in perfused hearts: Critical evaluation of the 5F-BAPTA and nuclear magnetic resonance method as applied to the study of ischemia and reperfusion. Circ Res 66:1255-67 (Pubitemid 20147742)
    • (1990) Circulation Research , vol.66 , Issue.5 , pp. 1255-1267
    • Marban, E.1    Kitakaze, M.2    Koretsune, Y.3    Yue, D.T.4    Chacko, V.P.5    Pike, M.M.6
  • 32
    • 65549103765 scopus 로고    scopus 로고
    • Incidence of and outcomes associated with ventricular tachycardia or fibrillation in patients undergoing primary percutaneous coronary intervention
    • Mehta RH, Starr AZ, Lopes RD, et al. (2009). Incidence of and outcomes associated with ventricular tachycardia or fibrillation in patients undergoing primary percutaneous coronary intervention. JAMA 301:1779-89
    • (2009) JAMA , vol.301 , pp. 1779-1789
    • Mehta, R.H.1    Starr, A.Z.2    Lopes, R.D.3
  • 33
    • 84857794627 scopus 로고    scopus 로고
    • Prognostic significance of postprocedural sustained ventricular tachycardia or fibrillation in patients undergoing primary percutaneous coronary intervention (from the HORIZONS-AMI Trial)
    • Mehta RH, Yu J, Piccini JP, et al. (2012). Prognostic significance of postprocedural sustained ventricular tachycardia or fibrillation in patients undergoing primary percutaneous coronary intervention (from the HORIZONS-AMI Trial). Am J Cardiol 109:805-12
    • (2012) Am J Cardiol , vol.109 , pp. 805-812
    • Mehta, R.H.1    Yu, J.2    Piccini, J.P.3
  • 34
    • 0002924686 scopus 로고    scopus 로고
    • Management of the patient with cardiac arrhythmias
    • Braunwald E, Zipes DP, Lippy P, eds. 6th ed. Philadelphia (PA): WB Saunders
    • Miller JM, Zipes DP. (2001). Management of the patient with cardiac arrhythmias. In: Braunwald E, Zipes DP, Lippy P, eds. Heart Disease: A Textbook of Cardiovascular Medicine. 6th ed. Philadelphia (PA): WB Saunders, 700-66
    • (2001) Heart Disease: A Textbook of Cardiovascular Medicine , pp. 700-766
    • Miller, J.M.1    Zipes, D.P.2
  • 36
    • 0029934789 scopus 로고    scopus 로고
    • An update review of saffron and its active constituents
    • DOI 10.1002/(SICI)1099-1573(199605)10:3<189::AID-PTR754>3.0.CO;2-C
    • Rios JL, Recio MC, Ginger RM, Manz S. (1996). An update review of saffron and its active constituents. Phytother Res 10:189-93 (Pubitemid 26164562)
    • (1996) Phytotherapy Research , vol.10 , Issue.3 , pp. 189-193
    • Rios, J.L.1    Recio, M.C.2    Giner, R.M.3    Menez, S.4
  • 37
    • 84864516665 scopus 로고    scopus 로고
    • Crocus sativus L. (saffron) attenuates isoproterenol-induced myocardial injury via preserving cardiac functions and strengthening antioxidant defense system
    • Sachdeva J, Tanwar V, Golechha M, et al. (2010). Crocus sativus L. (saffron) attenuates isoproterenol-induced myocardial injury via preserving cardiac functions and strengthening antioxidant defense system. Exp Toxicol Pathol 64:557-64
    • (2010) Exp Toxicol Pathol , vol.64 , pp. 557-564
    • Sachdeva, J.1    Tanwar, V.2    Golechha, M.3
  • 38
    • 84879403268 scopus 로고    scopus 로고
    • Reperfusion injury in acute myocardial infarction
    • Simonis G, Strasser RH, Ebner B. (2012). Reperfusion injury in acute myocardial infarction. Critical Care 16:A22
    • (2012) Critical Care , vol.16
    • Simonis, G.1    Strasser, R.H.2    Ebner, B.3
  • 39
    • 79959713672 scopus 로고    scopus 로고
    • Cardioprotective effects of pravastatin against lethal ventricular arrhythmias induced by reperfusion in the rat heart
    • Thuc LC, Teshima Y, Takahashi N, et al. (2011). Cardioprotective effects of pravastatin against lethal ventricular arrhythmias induced by reperfusion in the rat heart. Circ J 75:1601-8
    • (2011) Circ J , vol.75 , pp. 1601-1608
    • Thuc, L.C.1    Teshima, Y.2    Takahashi, N.3
  • 40
    • 0030209882 scopus 로고    scopus 로고
    • Openings of cardiac KATP channel by oxygen free radicals produced by xanthine oxidase reaction
    • Tokube K, Kiyosue T, Arita M. (1996). Openings of cardiac KATP channel by oxygen free radicals produced by xanthine oxidase reaction. Am J Physiol 271:H478-89
    • (1996) Am J Physiol , vol.271
    • Tokube, K.1    Kiyosue, T.2    Arita, M.3
  • 41
    • 0032417989 scopus 로고    scopus 로고
    • Effects of hydroxyl radicals on K(ATP) channels in guinea-pig ventricular myocytes
    • DOI 10.1007/s004240050760
    • Tokube K, Kiyosue T, Arita M. (1998). Effects of hydroxyl radicals on KATP channels in guinea-pig ventricular myocytes. Pflugers Arch 437:155-7 (Pubitemid 29071326)
    • (1998) Pflugers Archiv European Journal of Physiology , vol.437 , Issue.1 , pp. 155-157
    • Tokube, K.1    Kiyosue, T.2    Arita, M.3
  • 42
    • 0022610906 scopus 로고
    • QT prolongation and the anti-Arrhythmic efficacy of amiodarone
    • Torres V, Tepper D, Flowers D, et al. (1986). QT prolongation and the anti-Arrhythmic efficacy of amiodarone. J Am Coll Cardiol 7:142-7
    • (1986) J Am Coll Cardiol , vol.7 , pp. 142-147
    • Torres, V.1    Tepper, D.2    Flowers, D.3
  • 43
    • 80054801584 scopus 로고    scopus 로고
    • The protective effects of Saffron against the oxidative damage in a transient model of focal cerebral ischemia in rats
    • Vakili A, Eianali MR, Bandegi AR. (2011). The protective effects of Saffron against the oxidative damage in a transient model of focal cerebral ischemia in rats. Tehran Uni Med J 69:405-12
    • (2011) Tehran Uni Med J , vol.69 , pp. 405-412
    • Vakili, A.1    Eianali, M.R.2    Bandegi, A.R.3
  • 44
    • 85047679058 scopus 로고
    • The lambeth conventions: Guidelines for the study of arrhythmias in ischemia infarction, and reperfusion
    • Walker MJ, Curtis MJ, Hearse DJ, et al. (1988). The Lambeth Conventions: Guidelines for the study of arrhythmias in ischemia infarction, and reperfusion. Cardiovasc Res 22:447-55
    • (1988) Cardiovasc Res , vol.22 , pp. 447-455
    • Walker, M.J.1    Curtis, M.J.2    Hearse, D.J.3
  • 45
    • 0025690399 scopus 로고
    • Effects of amiodarone on cardiac electrophysiology and inducibility of arrhythmias in chronically infarcted dogs: Late arrhythmias, haemodynamics, and sympatholytic actions
    • Winslow E, Campbell JK, Barron E. (1990). Effects of amiodarone on cardiac electrophysiology and inducibility of arrhythmias in chronically infarcted dogs: Late arrhythmias, haemodynamics, and sympatholytic actions. J Cardiova Pharmacol 16:896-904
    • (1990) J Cardiova Pharmacol , vol.16 , pp. 896-904
    • Winslow, E.1    Campbell, J.K.2    Barron, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.