Effect of resveratrol and quercetin supplementation on redox status and inflammation after exercise

Applied Physiology, Nutrition and Metabolism

Volumn 38, Issue 7, 2013, Pages 760-765

  McAnulty, Lisa S ^a   Miller, Lindsey E ^b   Hosick, Peter A ^c   Utter, Alan C ^a   Quindry, John C ^b   McAnulty, Steven R ^a  

^a APPALACHIAN STATE UNIVERSITY   (United States)

^b AUBURN UNIVERSITY   (United States)

^c UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

Author keywords

Antioxidants; Cytokines; Exercise; F2 isoprostanes; Flavonoids; Oxidative stress

Indexed keywords

ANTIOXIDANT; QUERCETIN;

CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECTS; HUMAN; INFLAMMATION; METABOLISM; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; RANDOMIZED CONTROLLED TRIAL;

ANTIOXIDANTS; DOUBLE-BLIND METHOD; HUMANS; INFLAMMATION; OXIDATION-REDUCTION; OXIDATIVE STRESS; QUERCETIN;

EID: 84879325628     PISSN: 17155312     EISSN: 17155320     Source Type: Journal    
DOI: 10.1139/apnm-2012-0455     Document Type: Article

References (31)

1. Benzie, I.F., and Strain, J.J. 1996. The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay. Anal. Biochem. 239: 70-76. doi:10.1006/abio.1996.0292. PMID:8660627.
2. Borg, E., and Kaijser, L. 2006. A comparison between three rating scales for perceived exertion and two different work tests. Scand. J. Med. Sci. Sports, 16: 57-69.
3. Dill, D.B., and Costill, D.L. 1974. Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. J. Appl. Physiol. 37: 247-248. PMID:4850854.
4. Espin, J.C., Garcia-Conesa, M.T., and Tomas-Barberan, F.A. 2007. Nutraceuticals: facts and fiction. Phytochemistry, 68: 2986-3008. doi:10.1016/j.phytochem. 2007.09.014. PMID:17976666.
5. Ghanim, H., Sia, C.L., Abuaysheh, S., Korzeniewski, K., Patnaik, P., et al. 2010. An antiinflammatory and reactive oxygen species suppressive effects of an extract of Polygonum cuspidatum containing resveratrol. J. Clin. Endocrinol. Metab. 95: E1-E8. doi:10.1210/jc.2010-0482. PMID:20534755.
6. Guerra, R.S., Amaral, T.F., Marques, E., Mota, J., and Restivo, M.T. 2010. Accuracy of Siri and Brozek equations in the percent body fat estimation in older adults. J. Nutr. Health Aging, 14: 744-748. doi:10.1007/s12603-010-0112-z. PMID:21085903.
7. Jackson, A.S., Pollock, M.L., and Ward, A. 1980. Generalized equations for predicting body density of women. Med. Sci. Sports Exerc. 12: 175-181. PMID: 7402053.
8. Kao, C.L., Chen, L.K., Chang, Y.L., Yung, M.C., Hsu, C.C., et al. 2010. Resveratrol protects human endothelium from H(2)O(2)-induced oxidative stress and senescence via SirT1 activation. J. Atheroscler. Thromb. 17: 970-979. doi:10.5551/ jat.4333. PMID:20644332.
9. Loke, W.M., Proudfoot, J.M., Stewart, S., McKinley, A.J., Needs, P.W., et al. 2008. Metabolic transformation has a profound effect on anti-inflammatory activity of flavonoids such as quercetin: lack of association between antioxidant and lipoxygenase inhibitory activity. Biochem. Pharmacol. 75: 1045-1053. doi:10.1016/j.bcp.2007.11.002. PMID:18096136.
10. Manach, C., and Donovan, J.L. 2004. Pharmacokinetics and metabolism of dietary flavonoids in humans. Free Radic. Res. 38: 771-785. doi:10.1080/ 10715760410001727858. PMID:15493450.
11. Manach, C., Morand, C., Gil-Izquierdo, A., Bouteloup-Demange, C., and Rémésy, C. 2003. Bioavailability in humans of the flavanones hesperidin and narirutin after the ingestion of two doses of orange juice. Eur. J. Clin. Nutr. 57: 235-242. doi:10.1038/sj.ejcn.1601547. PMID:12571654.
12. Manach, C., Scalbert, A., Morand, C., Rémésy, C., and Jiménez, L. 2004. Polyphenols: food sources and bioavailability. Am. J. Clin. Nutr. 79: 727-747. PMID: 15113710.
13. Manach, C., Williamson, G., Morand, C., Scalbert, A., and Rémésy, C. 2005. Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. Am. J. Clin. Nutr. 81: 230S-242S.
14. Manach, C., Hubert, J., Llorach, R., and Scalbert, A. 2009. The complex links between dietary phytochemicals and human health deciphered by metabolomics. Mol. Nutr. Food Res. 53: 1303-1315. doi:10.1002/mnfr.200800516. PMID:19764066.
15. Marzetti, E., Wohlgemuth, S.E., Anton, S.D., Bernabei, R., Carter, C.S., et al. 2009. Cellular mechanisms of cardioprotection by calorie restriction: state of the science and future perspectives. Clin. Geriatr. Med. 25: 715-732, ix. doi:10. 1016/j.cger.2009.07.002. PMID:19944269.
16. McAnulty, S.R., McAnulty, L.S., Nieman, D.C., Quindry, J.C., Hosick, P.A., et al. 2008. Chronic quercetin ingestion and exercise-induced oxidative damage and inflammation. Appl. Physiol. Nutr. Metab. 33: 254-262. doi:10.1139/H07-177. PMID:18347680.
17. McAnulty, S.R., Nieman, D.C., McAnulty, L.S., Lynch, W.S., Jin, F., et al. 2011. Effect of mixed flavonoids, n-3 fatty acids, and vitamin C on oxidative stress and antioxidant capacity before and after intense cycling. Int. J. Sport Nutr. Exerc. Metab. 21: 328-337. PMID:21813916.
18. Mead, W.F. 1979. Maximal exercise testing-Bruce protocol. J. Fam. Pract. 9: 479-490. PMID:479779.
19. Morrow, J.D. 2006. The isoprostanes-unique products of arachidonate peroxidation: their role as mediators of oxidant stress. Curr. Pharm. Des. 12: 895-902. doi:10.2174/138161206776055985. PMID:16533158.
20. Morrow, J.D., and Roberts, L.J. 1997. The isoprostanes: unique bioactive products of lipid peroxidation. Prog. Lipid Res. 36: 1-21. doi:10.1016/S0163-7827(97)00001-5. PMID:9373618.
21. Morrow, J.D., and Roberts, L.J., II. 1999. Mass spectrometric quantification of F2-isoprostanes in biological fluids and tissues as measure of oxidant stress. Methods Enzymol. 300: 3-12. doi:10.1016/S0076-6879(99)00106-8. PMID: 9919502.
22. Morrow, J.D., and Roberts, L.J., II. 2002. Mass spectrometric quantification of F2-isoprostanes as indicators of oxidant stress. Methods Mol. Biol. 186: 57-66. PMID:12013785.
23. Nieman, D.C., Henson, D.A., Davis, J.M., Angela Murphy, E., Jenkins, D.P., et al. 2007a. Quercetin's influence on exercise-induced changes in plasma cytokines and muscle and leukocyte cytokine mRNA. J. Appl. Physiol. 103: 1728-1735. doi:10.1152/japplphysiol.00707.2007. PMID:17717114.
24. Nieman, D.C., Henson, D.A., Davis, J.M., Dumke, C.L., Gross, S.J., et al. 2007b. Quercetin ingestion does not alter cytokine changes in athletes competing in the Western States Endurance Run. J. Interferon Cytokine Res. 27: 1003-1011. doi:10.1089/jir.2007.0050. PMID:18184041.
25. Nieman, D.C., Henson, D.A., Maxwell, K.R., Williams, A.S., McAnulty, S.R., et al. 2009. Effects of quercetin and EGCG on mitochondrial biogenesis and immunity. Med. Sci. Sports Exerc. 41: 1467-1475. doi:10.1249/MSS.0b013e318199491f. PMID:19516153.
26. Nikolaidis, M.G., and Jamurtas, A.Z. 2009. Blood as a reactive species generator and redox status regulator during exercise. Arch. Biochem. Biophysiol. 490: 77-84. doi:10.1016/j.abb.2009.08.015.
27. Nikolaidis, M.G., Kyparos, A., and Vrabas, I.S. 2011. F2-isoprostane formation, measurement and interpretation: the role of exercise. Prog. Lipid Res. 50: 89-103. doi:10.1016/j.plipres.2010.10.002. PMID:20951733.
28. Olas, B., Nowak, P., Kolodziejczyk, J., Ponczek, M., and Wachowicz, B. 2006. Protective effects of resveratrol against oxidative/nitrative modifications of plasma proteins and lipids exposed to peroxynitrite. J. Nutr. Biochem. 17: 96-102. doi:10.1016/j.jnutbio.2005.05.010. PMID:16111878.
29. Powers, S.K., Duarte, J., Kavazis, A.N., and Talbert, E.E. 2010. Reactive oxygen species are signalling molecules for skeletal muscle adaptation. Exp. Physiol. 95: 1-9. doi:10.1113/expphysiol.2009.050526. PMID:19880534.
30. Veskoukis, A.S., Kyparos, A., Nikolaidis, M.G., Stagos, D., Aligiannis, N., et al. 2012. The antioxidant effects of a polyphenol-rich grape pomace extract in vitro do not correspond in vivo using exercise as an oxidant stimulus. Oxid. Med. Cell Longev. 2012: 185867. PMID:22693650.
31. Villano, D., Fernandez-Pachon, M.S., Troncoso, A.M., and Garcia-Parrilla, M.C. 2004. The antioxidant activity of wines determined by the ABTS(+) method: influence of sample dilution and time. Talanta, 64: 501-509. doi:10.1016/j. talanta.2004.03.021. PMID:18969632.