Microstructure, mechanical property, corrosion behavior, and in vitro biocompatibility of Zr-Mo alloys

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 101 B, Issue 2, 2013, Pages 237-246

  Zhou, F Y ^a   Wang, B L ^a   Qiu, K J ^a   Li, L ^a   Lin, J P ^b   Li, H F ^c   Zheng, Y F ^a,c  

^a HARBIN ENGINEERING UNIVERSITY   (China)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY BEIJING   (China)

^c PEKING UNIVERSITY   (China)

Author keywords

Corrosion; Cytotoxicity; Mechanical properties; Microstructure; Zr Mo alloys

Indexed keywords

ACICULAR STRUCTURES; BIOMEDICAL APPLICATIONS; CORROSION BEHAVIOR; CYTOTOXICITY TEST; DELETERIOUS EFFECTS; FIBROBLAST CELLS; OSTEOBLAST CELLS; SOLUTION TREATMENTS;

BIOCOMPATIBILITY; CELL CULTURE; CORROSION; CORROSION RESISTANCE; CORROSIVE EFFECTS; CYTOTOXICITY; ELECTROCHEMICAL CORROSION; MECHANICAL PROPERTIES; MEDICAL APPLICATIONS; MICROSTRUCTURE; MOLYBDENUM ALLOYS;

ZIRCONIUM;

ALLOY; MOLYBDENUM; ZIRCONIUM; BIOMATERIAL;

ANIMAL CELL; ARTICLE; BIOCOMPATIBILITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; CORROSION; CYTOTOXICITY; CYTOTOXICITY TEST; ELECTROCHEMISTRY; FIBROBLAST; HARDNESS; HUMAN; HUMAN CELL; IN VITRO STUDY; MECHANICS; NONHUMAN; OSTEOBLAST; STRENGTH; THERMODYNAMICS; YOUNG MODULUS; ANIMAL; BIOMECHANICS; CELL LINE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; ELECTROCHEMICAL ANALYSIS; MATERIALS TESTING; MOUSE; PHASE TRANSITION; SURFACE PROPERTY; TRANSMISSION ELECTRON MICROSCOPY; X RAY DIFFRACTION;

ALLOYS; ANIMALS; BIOCOMPATIBLE MATERIALS; BIOMECHANICS; CELL LINE; CORROSION; ELECTROCHEMICAL TECHNIQUES; FIBROBLASTS; HUMANS; MATERIALS TESTING; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; MOLYBDENUM; OSTEOBLASTS; PHASE TRANSITION; SURFACE PROPERTIES; X-RAY DIFFRACTION; ZIRCONIUM;

MLCS; MLOWN;

EID: 84879322146     PISSN: 15524973     EISSN: 15524981     Source Type: Journal    
DOI: 10.1002/jbm.b.32833     Document Type: Article

References (55)

1. Sherepo K, Parfenov A, Zusmanovich I. Application of zirconium alloys to endoprostheses and osteosynthesis appliances. Biomed Eng 1992;26:238-240.
2. Thomsen P, Larsson C, Ericson LE, Sennerby L, Lausmaa J, Kasemo B. Structure of the interface between rabbit cortical bone and implants of gold, zirconium and titanium. J Mater Sci Mater Med 1997;8:653-665.
3. Niinomi M. Recent titanium R&D for biomedical applications in japan. JOM 1999;51:32-34.
4. Sherepo KM, Red'ko IA. Use of zirconium-based and zirconiumcoated implants in traumatology and orthopedics. Biomed Eng 2004;38:77-79.
5. Hallab NJ, Anderson S, Caicedo M, Jacobs JJ. Zirconium and niobium affect human osteoblasts, fibroblasts, and lymphocytes in a similar manner to more traditional implant alloy metals. J ASTM Int 2006;3:429-440.
6. Guglielmotti MB, Renou S, Cabrini RL. A histomorphometric study of tissue interface by laminar implant test in rats. Int J Oral and Maxillofac Implants 1999;14:565-570.
7. Kulakov OB, Doktorov AA, Diakova SV, Denisov-Nikolskiy YI, Grötz KA. Experimental study of osseointegration of zirconium and titanium dental implants. Morfologiya 2005;127:52-55.
8. Uchida M, Kim HM, Miyaji F, Kokubo T, Nakamura T. Apatite formation on zirconium metal treated with aqueous NaOH. Biomaterials 2002;23:313-317.
9. Uchida M, Kim H-M, Kokubo T, Miyaji F, Nakamura T. Bonelike apatite formation induced on zirconia gel in a simulated body fluid and its modified solutions. J Am Ceram Soc 2001;84: 2041-2044.
10. Frandsen CJ, Brammer KS, Noh K, Connelly LS, Oh S, Chen L-H, Jin S. Zirconium oxide nanotube surface prompts increased osteoblast functionality and mineralization. Mater Sci Eng C 2011; 31:1716-1722.
11. Wang L-N, Adams A, Luo J-L. Enhancement of the capability of hydroxyapatite formation on Zr with anodic ZrO2 nanotubular arrays via an effective dipping pretreatment. J Biomed Mater Res Part B 2011;99:291-301.
12. Saldana L, Mendéz-Vilas A, Jiang L, Multigner M, González- Carrasco JL, Pérez-Prado MT, González-Martin ML, Munuera L, Vilaboa N. In vitro biocompatibility of an ultrafine grained zirconium. Biomaterials 2007;28:4343-4354.
13. Branzoi LV, Iordoc M, Codescu M. Electrochemical studies on the stability and corrosion resistance of new zirconium-based alloys for biomedical applications. Surf Interface Anal 2008;40:167-173.
14. Oliveira NTC, Biaggio SR, Rocha-Filho RC, Bocchi N. Electrochemical studies on zirconium and its biocompatible alloys Ti-50Zr at.% and Zr-2.5Nb wt.% in simulated physiologic media. J Biomed Mater Res Part A 2005;74:397-407
15. Satpati AK, Phadnis SV, Sundaresan RI. Electrochemical and XPS studies and the potential scan rate dependent pitting corrosion behavior of Zircaloy-2 in 5% NaCl solution. Corros Sci 2005;47: 1445-1458.
16. Zhou FY, Wang BL, Qiu KJ, Lin WJ, Li L, Wang YB, Nie FL, Zheng YF. Microstructure, corrosion behavior and cytotoxicity of Zr-Nb alloys for biomedical application. Mater Sci Eng C 2012;32: 851-857.
17. Kondo R, Suyalatu, Tsutsumi Y, Doi H, Nomura N, Hanawa T. Microstructure and mechanical properties of Pt-added and Pd-added Zr-20Nb alloys and their metal release in 1 mass% lactic acid solution. Mater Sci Eng C 2011;31:900-905.
18. Bozzini B, Carlino P, Mele C. Electrochemical behaviour and surface characterisation of Zr exposed to an SBF solution containing glycine, in view of dental implant applications. J Mater Sci Mater Med 2011;22:193-200.
19. Bran̂zoi V, Iordoc M, Brânzoi F, Sbarcea G, Marinescu V. Surface characterization and electrochemical behavior of new biomedical Zr-based metal/ceramic composite in fetal bovine serum. Rev Roum Chim 2010;55:585-597
20. Hobbs LW, Rosen VB, Mangin SP, Treska M, Hunter G. Oxidation microstructures and interfaces in the oxidized zirconium knee. Int J Appl Ceram Technol 2005;2:221-246
21. Lee JKL, Maruthainar K, Wardle N, Haddad F, Blunn GW. Increased force simulator wear testing of a zirconium oxide total knee arthroplasty. Knee 2009;16:269-274
22. Buczynski BW, Kory MM, Steiner RP, Kittinger TA, Ramsier RD. Bacterial adhesion to zirconium surfaces. Colloids Surf B 2003;30: 167-175
23. Bui FM, Bott K, Mintchev MP. A quantitative study of the pixelshifting, blurring and nonlinear distortions in MRI images caused by the presence of metal implants. J Med Eng Technol 2000;24: 20-27
24. Shafiei F, Honda E, Takahashi H, Sasaki T. Artifacts from dental casting alloys in magnetic resonance imaging. J Dent Res 2003; 82:602-606
25. Nomura SN, Oya K, Tanaka Y, Kondo R, Doi H, Tsutsumi Y, Hanawa T. Microstructure and magnetic susceptibility of as-cast Zr-Mo alloys. Acta Biomater 2010;6:1033-1038
26. Suyalatu, Kondo R, Tsutsumi Y, Doi H, Nomura N, Hanawa T.Effects of phase constitution on magnetic susceptibility and mechanical properties of Zr-rich Zr-Mo alloys. Acta Biomater 2011;7: 4259-4266
27. Kondo R, Nomura SN, Tsutsumi Y, Doi H, Hanawa T. Microstructure and mechanical properties of as-cast Zr-Nb alloys. Acta Biomater 2011;7:4278-4284
28. Okazaki Y, Rao S, Asao S, Tateishi T. Effects of metallic concentrations other than Ti, Al and V on cell viability. Mater Trans JIM 1998;39:1070-1079
29. Northwood DO. Heat treatment, transformation reactions and mechanical properties of two high strength zirconium alloys. J Less-Common Met 1978;61:199-212
30. Hsu H-C, Wu S-C, Sung Y-C, Ho W-F. The structure and mechanical properties of as-cast Zr-Ti alloys. J Alloys Compd 2009;488: 279-283
31. Kokubo T, Takadama H. How useful is SBF in predicting in vivo bone bioactivity? Biomaterials 2006;27:2907-2915
32. ISO-10993-5. Biological evaluation of medical devices-part 5: Test for in vitro cytotoxicity. Arlington, VA: ANSI/AAMI;1999
33. Slater JC. Atomic Radii in Crystals. J Chem Phys 1964;41: 3199-3204
34. Ho W-F, Chiang T-Y, Wu S-C, Hsu H-C. Mechanical properties and deformation behavior of cast binary Ti-Cr alloys. J Alloys Compd 2009;468:533-538
35. Mareci D, Chelariu R, Gordin D-M, Ungureanu G, Gloriant T. Comparative corrosion study of Ti-Ta alloys for dental applications. Acta Biomater 2009;5:3625-3639
36. Davydov AD. Breakdown of valve metal passivity induced by aggressive anions. Electrochim Acta 2001;46:3777-3781
37. Botstein O, Talianker M, Rabinkin A. Diffusionless omega transformations in quenched and pressurized Zr-Mo alloys. Acta Metall 1983;31:947-953
38. Song S, Gray G. Influence of temperature and strain rate on slip and twinning behavior of Zr. Metall Mater Trans A 1995;26: 2665-2675
39. Lee CM, Ju CP, Chern Lin JH. Structure-property relationship of cast Ti-Nb alloys. J Oral Rehabil 2002;29:314-322
40. Ho W-F, Wu S-C, Hsu S-K, Li Y-C, Hsu H-C. Effects of molybdenum content on the structure and mechanical properties of as-cast Ti-10Zr-based alloys for biomedical applications. Mater Sci Eng C 2012;32:517-522
41. Stewart TD, Hall RM. Basic biomechanics of human joints: Hips, knees and the spine. Curr Orthop 2006;20:23-31.
42. Huiskes R. The various stress patterns of press-fit, ingrown,and cemented femoral stems. Clin Orthop 1990;261:27-38.
43. Roy ME, Whiteside LA, Xu J, Katerberg BJ. Diamond-like carbon coatings enhance the hardness and resilience of bearing surfaces for use in joint arthroplasty. Acta Biomater 2010;6:1619-1624.
44. Niinomi M, Nakai M. Titanium-based biomaterials for preventing stress shielding between implant devices and bone. Int J Biomater 2011;2011:1-10.
45. Tsutsumi Y, Takano Y, Doi H, Noda K, Hanawa T. Corrosion behavior of zirconium based alloys in simulated body fluids. Mater Sci Forum 2007;561-565:1489-1492.
46. Palit GC, Gadiyar HS. Pitting corrosion of zirconium in chloride solution. Corrosion 1987;43:140-148.
47. Oliveira NTC, Guastaldi AC. Electrochemical behavior of Ti-Mo alloys applied as biomaterial. Corros Sci 2008;50:938-945.
48. Oliveira NTC, Guastaldi AC, Piazza S, Sunseri C. Photo-electrochemical investigation of anodic oxide films on cast Ti-Mo alloys. I. Anodic behaviour and effect of alloy composition. Electrochim Acta 2009;54:1395-1402.
49. Eisenbarth E, Velten D, Müller M, Thull R, Breme J. Biocompatibility of beta-stabilizing elements of titanium alloys. Biomaterials 2004;25:5705-5713.
50. Liu L, Qiu CL, Chen Q, Chan KC, Zhang SM. Deformation behavior, corrosion resistance, and cytotoxicity of Ni-free Zr-based bulk metallic glasses. J Biomed Mater Res Part A 2008; 86:160-169.
51. Yun YH, Turitto VT, Daigle KP, Kovacs P, Davidson JA, Slack SM. Initial hemocompatibility studies of titanium and zirconium alloys: Prekallikrein activation, fibrinogen adsorption, and their correlation with surface electrochemical properties. J Biomed Mater Res 1996;32:77-85.
52. Vyskocil A, Viau C. Assessment of molybdenum toxicity in humans. J Appl Toxicol 1999;19:185-192.
53. Niinomi M. Recent research and development in titanium alloys for biomedical applications and healthcare goods. Sci Technol Adv Mater 2003;4:445-454.
54. Lugowski SJ, Smith DC, McHugh AD, Van Loon JC. Release of metal ions from dental implant materials in vivo: Determination of Al, Co, Cr, Mo, Ni, V, and Ti in organ tissue. J Biomed Mater Res 1991;25:1443-1458.
55. Hallab NJ, Anderson S, Caicedo M, Brasher A, Mikecz K, Jacobs JJ. Effects of soluble metals on human peri-implant cells. J Biomed Mater Res Part A 2005;74:124-140.