Desensitization of G-protein-coupled receptors induces vascular hypocontractility in response to norepinephrine in the mesenteric arteries of cirrhotic patients and rats

Hepatobiliary and Pancreatic Diseases International

Volumn 12, Issue 3, 2013, Pages 295-304

  Chen, Wei ^a   Sang, Jiang Yong ^b   Liu, De Jun ^a   Qin, Jun ^a   Huo, Yan Miao ^a   Xu, Jia ^a   Wu, Zhi Yong ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b The Second People's Hospital of Kashi   (China)

Author keywords

Desensitization; G protein coupled receptors; Portal hypertension; Rho associated coiled coil forming protein kinase; arrestin 2

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ANTIVIRUS AGENT; BETA ARRESTIN 2; CARBON TETRACHLORIDE; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR KINASE 2; GUANINE NUCLEOTIDE BINDING PROTEIN; NORADRENALIN; PROTEIN KINASE; RHO ASSOCIATED COILED COIL FORMING PROTEIN KINASE 1; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIOLE; ARTERY CONSTRICTION; ARTICLE; CONTROLLED STUDY; DESENSITIZATION; ENZYME ACTIVITY; HEPATITIS B; HUMAN; LIVER CIRRHOSIS; MESENTERIC ARTERY; NONHUMAN; PORTAL VEIN BLOOD PRESSURE; PROTEIN EXPRESSION; RAT; VASCULAR DISEASE; VASCULAR HYPOCONTRACTILITY; WESTERN BLOTTING;

EID: 84879294914     PISSN: 14993872     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1499-3872(13)60047-8     Document Type: Article

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