Biphasic modulation of nos expression, protein and nitrite products by hydroxocobalamin underlies its protective effect in endotoxemic shock: Downstream regulation of COX-2, IL-1 β, TNF-α, IL-6, and HMGB1 expression

Mediators of Inflammation

Volumn 2013, Issue , 2013, Pages

  Sampaio, André L F ^a,b   Dalli, Jesmond ^a,c   Brancaleone, Vincenzo ^a   D'Acquisto, Fulvio ^a   Perretti, Mauro ^a   Wheatley, Carmen ^d,e  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c UNIVERSITY OF BASILICATA   (Italy)

^d Orthomolecular Oncology   (United Kingdom)

^e UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HIGH MOBILITY GROUP B1 PROTEIN; HYDROXOCOBALAMIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRITE; PROTEIN; TUMOR NECROSIS FACTOR ALPHA; GALACTOSAMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATTENUATION; BIOASSAY; CONTROLLED STUDY; DRUG EFFICACY; DRUG INHIBITION; ENDOTOXEMIA; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GRIESS ASSAY; IMMUNE RESPONSE; LIVER; LUNG; MALE; MEDIATOR; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; QUANTITATIVE ANALYSIS; RECEPTOR DOWN REGULATION; SEPSIS; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; DRUG EFFECT; ENZYMOLOGY; GENETICS; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; DRUG EFFECTS;

MUS;

ANIMALS; BLOTTING, WESTERN; CYCLOOXYGENASE 2; ENDOTOXEMIA; GALACTOSAMINE; HMGB1 PROTEIN; HYDROXOCOBALAMIN; INTERLEUKIN-1BETA; INTERLEUKIN-6; LIVER; LUNG; MALE; MICE; MICE, INBRED C57BL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84879292346     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2013/741804     Document Type: Article

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