Pulmonary natural killer T cells play an essential role in mediating hyperoxic acute lung injury

American Journal of Respiratory Cell and Molecular Biology

Volumn 48, Issue 5, 2013, Pages 601-609

  Nowak Machen, Martina ^a,b   Schmelzle, Moritz ^b   Hanidziar, Dusan ^b   Junger, Wolfgang ^b   Exley, Mark ^b   Otterbein, Leo ^b   Wu, Yan ^b   Csizmadia, Eva ^b   Doherty, Glen ^c   Sitkovsky, Michail ^d   Robson, Simon C ^b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

^d NORTHEASTERN UNIVERSITY   (United States)

Author keywords

ATP; Immunology; Lung injury; Oxygen; P2X7

Indexed keywords

ADENOSINE TRIPHOSPHATE DEPENDENT PROTEINASE; CD39 ANTIGEN; OXYGEN; PURINERGIC P2X7 RECEPTOR; APYRASE; CYTOKINE; LEUKOCYTE ANTIGEN;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL DEATH; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPEROXIA; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS CELL; MOLECULAR PATHOLOGY; MOUSE; NATURAL KILLER T CELL; NONHUMAN; SIGNAL TRANSDUCTION; TISSUE INJURY; WILD TYPE; ADOPTIVE TRANSFER; ANIMAL; APOPTOSIS; C57BL MOUSE; CELL CULTURE; ENZYMOLOGY; GENETICS; IMMUNOLOGY; LUNG; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE MUTANT; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; PATHOLOGY; PHYSIOLOGY; SECRETION (PROCESS);

ACUTE LUNG INJURY; ADOPTIVE TRANSFER; ANIMALS; ANTIGENS, CD; APOPTOSIS; APYRASE; CELL PROLIFERATION; CELLS, CULTURED; CYTOKINES; HYPEROXIA; LUNG; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NATURAL KILLER T-CELLS; NEUTROPHIL INFILTRATION; NEUTROPHILS;

MLCS; MLOWN;

EID: 84879290427     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2012-0180OC     Document Type: Article

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