Computational Model of Gab1/2-Dependent VEGFR2 Pathway to Akt Activation

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Tan, Wan Hua ^a   Popel, Aleksander S ^a   Mac Gabhann, Feilim ^b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Johns Hopkins University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN GAB1; PROTEIN GAB2; PROTEIN KINASE B; PROTEIN TYROSINE PHOSPHATASE SHP 2; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2; GAB1 PROTEIN, HUMAN; GAB2 PROTEIN, HUMAN; KDR PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 3 KINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ACCURACY; ANALYTIC METHOD; ARTICLE; BINDING AFFINITY; COMPARATIVE STUDY; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; ENZYME ACTIVATION; MASS ACTION MODEL; MATHEMATICAL MODEL; PREDICTION; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIMULATION; TRAFFICKING PARAMETER; VALIDITY; BIOLOGICAL MODEL; COMPUTER SIMULATION; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; COMPUTER SIMULATION; ENZYME ACTIVATION; HUMANS; MODELS, BIOLOGICAL; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 84879258629     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0067438     Document Type: Article

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