Structure-activity relationship studies of 5,7-dihydroxyflavones as naturally occurring inhibitors of cell proliferation in human leukemia HL-60 cells

Journal of Natural Medicines

Volumn 67, Issue 3, 2013, Pages 460-467

  Ninomiya, Masayuki ^a   Nishida, Kyohei ^a   Tanaka, Kaori ^a   Watanabe, Kunitomo ^a   Koketsu, Mamoru ^a  

^a GIFU UNIVERSITY   (Japan)

Author keywords

5,7 Dihydroxyflavone; Antiproliferative activity; Apoptosis; Cell differentiation; Human promyelocytic leukemia HL 60 cell

Indexed keywords

3',4' DIMETHOXYLUTEOLIN; 3',4',5' TRIMETHOXYTRICETIN; 4' METHOXYTRICETIN; 5,7 DIHYDROXYFLAVONE DERIVATIVE; ACACETIN; APOMETZGERIN; CHRYSOERIOL; DIOSMETIN; FLAVONE DERIVATIVE; TRICETIN; TRICIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRAIN HL 60; CELL STRUCTURE; CONTROLLED STUDY; DRUG POTENCY; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; FLAVONES; FLAVONOIDS; HL-60 CELLS; HUMANS; LEUKEMIA; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84879218128     PISSN: 13403443     EISSN: 18610293     Source Type: Journal    
DOI: 10.1007/s11418-012-0697-0     Document Type: Article

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