Spica prunellae promotes cancer cell apoptosis, inhibits cell proliferation and tumor angiogenesis in a mouse model of colorectal cancer via suppression of stat3 pathway

BMC Complementary and Alternative Medicine

Volumn 13, Issue , 2013, Pages

  Lin, Wei ^a   Zheng, Liangpu ^a   Zhuang, Qunchuan ^a   Zhao, Jinyan ^a   Cao, Zhiyun ^a   Zeng, Jianwei ^a   Lin, Shan ^a   Xu, Wei ^a   Peng, Jun ^a  

^a FUJIAN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Angiogenesis; Apoptosis; Colorectal cancer; Herbal medicine; Proliferation; Spica prunellae; STAT3 pathway

Indexed keywords

ALCOHOL; ANTINEOPLASTIC AGENT; CD31 ANTIGEN; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; MESSENGER RNA; PLANT EXTRACT; PROTEIN BAX; PROTEIN BCL 2; SPICA PRUNELLAE EXTRACT; STAT3 PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BODY WEIGHT; CANCER CELL; CAPILLARY DENSITY; CELL PROLIFERATION; CELL VIABILITY; COLON CARCINOMA; COLORECTAL CANCER; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PRUNELLA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPICA PRUNELLAE; TREATMENT DURATION; TUMOR GROWTH; TUMOR VOLUME; TUMOR XENOGRAFT; WEIGHT CHANGE;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL PROLIFERATION; COLORECTAL NEOPLASMS; DISEASE MODELS, ANIMAL; DOWN-REGULATION; HT29 CELLS; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MITOCHONDRIA; NEOVASCULARIZATION, PATHOLOGIC; PHYTOTHERAPY; PLANT EXTRACTS; PRUNELLA; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; VASCULAR ENDOTHELIAL GROWTH FACTOR A; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84879203540     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-13-144     Document Type: Article

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