메뉴 건너뛰기




Volumn 184, Issue 6, 2010, Pages 3164-3173

Small-molecule inhibitors of vascular adhesion protein-1 reduce the accumulation of myeloid cells into tumors and attenuate tumor growth in mice

Author keywords

[No Author keywords available]

Indexed keywords

2 (1 METHYLHYDRAZINO) 1 INDANOL; 3 FLUORO 2 (4 METHOXYBENZYL)ALLYLAMINE HYDROCHLORIDE; CD11B ANTIGEN; LJP 1586; MONOCLONAL ANTIBODY; PROTEIN INHIBITOR; SZE 5302; UNCLASSIFIED DRUG; VASCULAR ADHESION PROTEIN 1; VASCULAR ADHESION PROTEIN 1 MONOCLONAL ANTIBODY; 3 FLUORO 2 (4 METHOXYBENZYL)ALLYLAMINE; 3-FLUORO-2-(4-METHOXYBENZYL)ALLYLAMINE; ALLYLAMINE; AMINE OXIDASE (COPPER CONTAINING); BLOCKING ANTIBODY; CARBAMOHYDRAZIDE; CELL ADHESION MOLECULE; DRUG DERIVATIVE; ENZYME INHIBITOR; GROWTH INHIBITOR; IMMUNOLOGICAL ADJUVANT; SEMICARBAZIDE DERIVATIVE; SEMICARBAZIDE SENSITIVE AMINE OXIDASE VASCULAR ADHESION PROTEIN 1, MOUSE; SEMICARBAZIDE-SENSITIVE AMINE OXIDASE-VASCULAR ADHESION PROTEIN-1, MOUSE;

EID: 77951909461     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0901794     Document Type: Article
Times cited : (31)

References (44)
  • 2
    • 34548230927 scopus 로고    scopus 로고
    • Getting to the site of inflammation: The leukocyte adhesion cascade updated
    • Ley, K., C. Laudanna, M. I. Cybulsky, and S. Nourshargh. 2007. Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat. Rev. Immunol. 7: 678-689.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 678-689
    • Ley, K.1    Laudanna, C.2    Cybulsky, M.I.3    Nourshargh, S.4
  • 3
    • 3042822267 scopus 로고    scopus 로고
    • Cancer and the chemokine network
    • Balkwill, F. 2004. Cancer and the chemokine network. Nat. Rev. Cancer 4: 540-550.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 540-550
    • Balkwill, F.1
  • 4
    • 0034925160 scopus 로고    scopus 로고
    • VAP-1: An adhesin and an enzyme
    • Salmi, M., and S. Jalkanen. 2001. VAP-1: an adhesin and an enzyme. Trends Immunol. 22: 211-216.
    • (2001) Trends Immunol. , vol.22 , pp. 211-216
    • Salmi, M.1    Jalkanen, S.2
  • 5
    • 0027368071 scopus 로고
    • Induction and function of vascular adhesion protein-1 at sites of inflammation
    • Salmi, M., K. Kalimo, and S. Jalkanen. 1993. Induction and function of vascular adhesion protein-1 at sites of inflammation. J. Exp. Med. 178: 2255-2260.
    • (1993) J. Exp. Med. , vol.178 , pp. 2255-2260
    • Salmi, M.1    Kalimo, K.2    Jalkanen, S.3
  • 6
    • 0026757630 scopus 로고
    • A 90-kilodalton endothelial cell molecule mediating lymphocyte binding in humans
    • Salmi, M., and S. Jalkanen. 1992. A 90-kilodalton endothelial cell molecule mediating lymphocyte binding in humans. Science 257: 1407-1409.
    • (1992) Science , vol.257 , pp. 1407-1409
    • Salmi, M.1    Jalkanen, S.2
  • 10
    • 0030057684 scopus 로고    scopus 로고
    • Human vascular adhesion protein 1 (VAP-1) is a unique sialoglycoprotein that mediates carbohydrate-dependent binding of lymphocytes to endothelial cells
    • Salmi, M., and S. Jalkanen. 1996. Human vascular adhesion protein 1 (VAP-1) is a unique sialoglycoprotein that mediates carbohydrate-dependent binding of lymphocytes to endothelial cells. J. Exp. Med. 183: 569-579.
    • (1996) J. Exp. Med. , vol.183 , pp. 569-579
    • Salmi, M.1    Jalkanen, S.2
  • 11
    • 0030807630 scopus 로고    scopus 로고
    • Vascular adhesion protein 1 (VAP-1) mediates lymphocyte subtype-specific, selectin-independent recognition of vascular endothelium in human lymph nodes
    • Salmi, M., S. Tohka, E. L. Berg, E. C. Butcher, and S. Jalkanen. 1997. Vascular adhesion protein 1 (VAP-1) mediates lymphocyte subtype-specific, selectin-independent recognition of vascular endothelium in human lymph nodes. J. Exp. Med. 186: 589-600.
    • (1997) J. Exp. Med. , vol.186 , pp. 589-600
    • Salmi, M.1    Tohka, S.2    Berg, E.L.3    Butcher, E.C.4    Jalkanen, S.5
  • 12
    • 0035124160 scopus 로고    scopus 로고
    • Vascular adhesion protein 1 (VAP-1) functions as a molecular brake during granulocyte rolling and mediates recruitment in vivo
    • DOI 10.1096/fj.00-0240com
    • Tohka, S., M.-L. Laukkanen, S. Jalkanen, and M. Salmi. 2001. Vascular adhesion protein 1 (VAP-1) functions as a molecular brake during granulocyte rolling and mediates recruitment in vivo. FASEB J. 15: 373-382. (Pubitemid 32141429)
    • (2001) FASEB Journal , vol.15 , Issue.2 , pp. 373-382
    • Tohka, S.1    Laukkanen, M.-L.2    Jalkanen, S.3    Salmi, M.4
  • 13
    • 0037100288 scopus 로고    scopus 로고
    • Vascular adhesion protein-1 mediates adhesion and transmigration of lymphocytes on human hepatic endothelial cells
    • Lalor, P. F., S. Edwards, G. McNab, M. Salmi, S. Jalkanen, and D. H. Adams. 2002. Vascular adhesion protein-1 mediates adhesion and transmigration of lymphocytes on human hepatic endothelial cells. J. Immunol. 169: 983-992.
    • (2002) J. Immunol. , vol.169 , pp. 983-992
    • Lalor, P.F.1    Edwards, S.2    McNab, G.3    Salmi, M.4    Jalkanen, S.5    Adams, D.H.6
  • 15
    • 1942456908 scopus 로고    scopus 로고
    • Granulocyte transmigration through the endothelium is regulated by the oxidase activity of vascular adhesion protein-1 (VAP-1)
    • DOI 10.1182/blood-2003-09-3275
    • Koskinen, K., P. J. Vainio, D. J. Smith, M. Pihlavisto, S. Ylä-Herttuala, S. Jalkanen, and M. Salmi. 2004. Granulocyte transmigration through the endothelium is regulated by the oxidase activity of vascular adhesion protein-1 (VAP-1). Blood 103: 3388-3395. (Pubitemid 38525669)
    • (2004) Blood , vol.103 , Issue.9 , pp. 3388-3395
    • Koskinen, K.1    Vainio, P.J.2    Smith, D.J.3    Pihlavisto, M.4    Yla-Herttuala, S.5    Jalkanen, S.6    Salmi, M.7
  • 16
    • 33645126638 scopus 로고    scopus 로고
    • Vascular adhesion protein-1 plays an important role in postischemic inflammation and neuropathology in diabetic, estrogen-treated ovariectomized female rats subjected to transient forebrain ischemia
    • Xu, H.-L., L. Salter-Cid, M. D. Linnik, E. Y. Wang, C. Paisansathan, and D. A. Pelligrino. 2006. Vascular adhesion protein-1 plays an important role in postischemic inflammation and neuropathology in diabetic, estrogen-treated ovariectomized female rats subjected to transient forebrain ischemia. J. Pharmacol. Exp. Ther. 317: 19-29.
    • (2006) J. Pharmacol. Exp. Ther. , vol.317 , pp. 19-29
    • Xu, H.-L.1    Salter-Cid, L.2    Linnik, M.D.3    Wang, E.Y.4    Paisansathan, C.5    Pelligrino, D.A.6
  • 17
    • 38749108448 scopus 로고    scopus 로고
    • Anti-inflammatory effects of LJP 1586 [Z-3-fluoro-2-(4-methoxybenzyl) allylamine hydrochloride], an amine-based inhibitor of semicarbazide-sensitive amine oxidase activity
    • O'Rourke, A. M., E. Y. Wang, A. Miller, E. M. Podar, K. Scheyhing, L. Huang, C. Kessler, H. Gao, H. T. Ton-Nu, M. T. Macdonald, et al. 2008. Anti-inflammatory effects of LJP 1586 [Z-3-fluoro-2-(4-methoxybenzyl)allylamine hydrochloride], an amine-based inhibitor of semicarbazide-sensitive amine oxidase activity. J. Pharmacol. Exp. Ther. 324: 867-875.
    • (2008) J. Pharmacol. Exp. Ther. , vol.324 , pp. 867-875
    • O'Rourke, A.M.1    Wang, E.Y.2    Miller, A.3    Podar, E.M.4    Scheyhing, K.5    Huang, L.6    Kessler, C.7    Gao, H.8    Ton-Nu, H.T.9    Macdonald, M.T.10
  • 21
    • 25844523991 scopus 로고    scopus 로고
    • Cell-surface enzymes in control of leukocyte trafficking
    • Salmi, M., and S. Jalkanen. 2005. Cell-surface enzymes in control of leukocyte trafficking. Nat. Rev. Immunol. 5: 760-771.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 760-771
    • Salmi, M.1    Jalkanen, S.2
  • 26
    • 14644393680 scopus 로고    scopus 로고
    • Vascular adhesion protein-1 is involved in both acute and chronic inflammation in the mouse
    • Merinen, M., H. Irjala, M. Salmi, I. Jaakkola, A. Hänninen, and S. Jalkanen. 2005. Vascular adhesion protein-1 is involved in both acute and chronic inflammation in the mouse. Am. J. Pathol. 166: 793-800.
    • (2005) Am. J. Pathol. , vol.166 , pp. 793-800
    • Merinen, M.1    Irjala, H.2    Salmi, M.3    Jaakkola, I.4    Hänninen, A.5    Jalkanen, S.6
  • 29
    • 0030922748 scopus 로고    scopus 로고
    • Homing of mucosal leukocytes to joints. Distinct endothelial ligands in synovium mediate leukocyte-subtype specific adhesion
    • Salmi, M., P. Rajala, and S. Jalkanen. 1997. Homing of mucosal leukocytes to joints. Distinct endothelial ligands in synovium mediate leukocyte-subtype specific adhesion. J. Clin. Invest. 99: 2165-2172.
    • (1997) J. Clin. Invest. , vol.99 , pp. 2165-2172
    • Salmi, M.1    Rajala, P.2    Jalkanen, S.3
  • 31
    • 0017088029 scopus 로고
    • Lymphocyte homing into lymph nodes: In vitro demonstration of the selective affinity of recirculating lymphocytes for high-endothelial venules
    • Stamper, H. B., Jr., and J. J. Woodruff. 1976. Lymphocyte homing into lymph nodes: in vitro demonstration of the selective affinity of recirculating lymphocytes for high-endothelial venules. J. Exp. Med. 144: 828-833.
    • (1976) J. Exp. Med. , vol.144 , pp. 828-833
    • Stamper Jr., H.B.1    Woodruff, J.J.2
  • 32
    • 33847216148 scopus 로고    scopus 로고
    • Endothelial cell adhesion molecules and cancer progression
    • Kobayashi, H., K. C. Boelte, and P. C. Lin. 2007. Endothelial cell adhesion molecules and cancer progression. Curr. Med. Chem. 14: 377-386.
    • (2007) Curr. Med. Chem. , vol.14 , pp. 377-386
    • Kobayashi, H.1    Boelte, K.C.2    Lin, P.C.3
  • 33
    • 58149349910 scopus 로고    scopus 로고
    • Ischemia-reperfusion injury is attenuated in VAP-1-deficient mice and by VAP-1 inhibitors
    • Kiss, J., S. Jalkanen, F. Fülöp, T. Savunen, and M. Salmi. 2008. Ischemia-reperfusion injury is attenuated in VAP-1-deficient mice and by VAP-1 inhibitors. Eur. J. Immunol. 38: 3041-3049.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 3041-3049
    • Kiss, J.1    Jalkanen, S.2    Fülöp, F.3    Savunen, T.4    Salmi, M.5
  • 35
    • 53349099219 scopus 로고    scopus 로고
    • Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein
    • Cheng, P., C. A. Corzo, N. Luetteke, B. Yu, S. Nagaraj, M. M. Bui, M. Ortiz, W. Nacken, C. Sorg, T. Vogl, et al. 2008. Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein. J. Exp. Med. 205: 2235-2249.
    • (2008) J. Exp. Med. , vol.205 , pp. 2235-2249
    • Cheng, P.1    Corzo, C.A.2    Luetteke, N.3    Yu, B.4    Nagaraj, S.5    Bui, M.M.6    Ortiz, M.7    Nacken, W.8    Sorg, C.9    Vogl, T.10
  • 36
    • 33847732713 scopus 로고    scopus 로고
    • Activation of vascular adhesion protein-1 on liver endothelium results in an NF-κB-dependent increase in lymphocyte adhesion
    • Lalor, P. F., P. J. Sun, C. J. Weston, A. Martin-Santos, M. J. Wakelam, and D. H. Adams. 2007. Activation of vascular adhesion protein-1 on liver endothelium results in an NF-κB-dependent increase in lymphocyte adhesion. Hepatology 45: 465-474.
    • (2007) Hepatology , vol.45 , pp. 465-474
    • Lalor, P.F.1    Sun, P.J.2    Weston, C.J.3    Martin-Santos, A.4    Wakelam, M.J.5    Adams, D.H.6
  • 37
    • 34548825637 scopus 로고    scopus 로고
    • The oxidase activity of vascular adhesion protein-1 (VAP-1) induces endothelial E- And P-selectins and leukocyte binding
    • DOI 10.1182/blood-2007-01-069674
    • Jalkanen, S., M. Karikoski, N. Mercier, K. Koskinen, T. Henttinen, K. Elima, K. Salmivirta, and M. Salmi. 2007. The oxidase activity of vascular adhesion protein-1 (VAP-1) induces endothelial E- and P-selectins and leukocyte binding. Blood 110: 1864-1870. (Pubitemid 47443898)
    • (2007) Blood , vol.110 , Issue.6 , pp. 1864-1870
    • Jalkanen, S.1    Karikoski, M.2    Mercier, N.3    Koskinen, K.4    Henttinen, T.5    Elima, K.6    Salmivirta, K.7    Salmi, M.8
  • 38
    • 36348938884 scopus 로고    scopus 로고
    • Reactive oxygen species regulate angiogenesis and tumor growth through vascular endothelial growth factor
    • DOI 10.1158/0008-5472.CAN-07-0783
    • Xia, C., Q. Meng, L. Z. Liu, Y. Rojanasakul, X. R. Wang, and B. H. Jiang. 2007. Reactive oxygen species regulate angiogenesis and tumor growth through vascular endothelial growth factor. Cancer Res. 67: 10823-10830. (Pubitemid 350145911)
    • (2007) Cancer Research , vol.67 , Issue.22 , pp. 10823-10830
    • Xia, C.1    Meng, Q.2    Liu, L.-Z.3    Rojanasakul, Y.4    Wang, X.-R.5    Jiang, B.-H.6
  • 39
    • 43549095196 scopus 로고    scopus 로고
    • p53 phosphorylation is involved in vascular cell death induced by the catalytic activity of membrane-bound SSAO/VAP-1
    • Solé, M., M. Hernandez-Guillamon, M. Boada, and M. Unzeta. 2008. p53 phosphorylation is involved in vascular cell death induced by the catalytic activity of membrane-bound SSAO/VAP-1. Biochim. Biophys. Acta 1783: 1085-1094.
    • (2008) Biochim. Biophys. Acta , vol.1783 , pp. 1085-1094
    • Solé, M.1    Hernandez-Guillamon, M.2    Boada, M.3    Unzeta, M.4
  • 40
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich, D. I., and S. Nagaraj. 2009. Myeloid-derived suppressor cells as regulators of the immune system. Nat. Rev. Immunol. 9: 162-174.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 41
    • 0032522844 scopus 로고    scopus 로고
    • Vascular adhesion protein-1 and ICAM-1 support the adhesion of tumor-infiltrating lymphocytes to tumor endothelium in human hepatocellular carcinoma
    • Yoong, K. F., G. McNab, S. G. Hübscher, and D. H. Adams. 1998. Vascular adhesion protein-1 and ICAM-1 support the adhesion of tumor-infiltrating lymphocytes to tumor endothelium in human hepatocellular carcinoma. J. Immunol. 160: 3978-3988.
    • (1998) J. Immunol. , vol.160 , pp. 3978-3988
    • Yoong, K.F.1    McNab, G.2    Hübscher, S.G.3    Adams, D.H.4
  • 42
    • 0035336167 scopus 로고    scopus 로고
    • Vascular adhesion protein 1 mediates binding of immunotherapeutic effector cells to tumor endothelium
    • Irjala, H., M. Salmi, K. Alanen, R. Grénman, and S. Jalkanen. 2001. Vascular adhesion protein 1 mediates binding of immunotherapeutic effector cells to tumor endothelium. J. Immunol. 166: 6937-6943. (Pubitemid 32467241)
    • (2001) Journal of Immunology , vol.166 , Issue.11 , pp. 6937-6943
    • Irjala, H.1    Salmi, M.2    Alanen, K.3    Grenman, R.4    Jalkanen, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.