-
2
-
-
0034677646
-
A novel transcription factor, T-bet, directs Th1 lineage commitment
-
Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, et al. (2000) A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 100: 655-669.
-
(2000)
Cell
, vol.100
, pp. 655-669
-
-
Szabo, S.J.1
Kim, S.T.2
Costa, G.L.3
Zhang, X.4
Fathman, C.G.5
-
3
-
-
0029876629
-
Stat6 is required for mediating responses to IL-4 and for development of Th2 cells
-
Kaplan MH, Schindler U, Smiley ST, Grusby MJ, (1996) Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity 4: 313-319.
-
(1996)
Immunity
, vol.4
, pp. 313-319
-
-
Kaplan, M.H.1
Schindler, U.2
Smiley, S.T.3
Grusby, M.J.4
-
4
-
-
0030810155
-
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
-
Zheng W, Flavell RA, (1997) The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 89: 587-596.
-
(1997)
Cell
, vol.89
, pp. 587-596
-
-
Zheng, W.1
Flavell, R.A.2
-
5
-
-
0030764961
-
Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene
-
Zhang DH, Cohn L, Ray P, Bottomly K, Ray A, (1997) Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene. J Biol Chem 272: 21597-21603.
-
(1997)
J Biol Chem
, vol.272
, pp. 21597-21603
-
-
Zhang, D.H.1
Cohn, L.2
Ray, P.3
Bottomly, K.4
Ray, A.5
-
6
-
-
33748588423
-
The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells
-
Ivanov, II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, et al. (2006) The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 126: 1121-1133.
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
Tadokoro, C.E.4
Lepelley, A.5
-
7
-
-
37849048599
-
T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma
-
Yang XO, Pappu BP, Nurieva R, Akimzhanov A, Kang HS, et al. (2008) T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma. Immunity 28: 29-39.
-
(2008)
Immunity
, vol.28
, pp. 29-39
-
-
Yang, X.O.1
Pappu, B.P.2
Nurieva, R.3
Akimzhanov, A.4
Kang, H.S.5
-
8
-
-
62049085937
-
Critical role of the Polycomb and Trithorax complexes in the maintenance of CD4 T cell memory
-
Nakayama T, Yamashita M, (2009) Critical role of the Polycomb and Trithorax complexes in the maintenance of CD4 T cell memory. Semin Immunol 21: 78-83.
-
(2009)
Semin Immunol
, vol.21
, pp. 78-83
-
-
Nakayama, T.1
Yamashita, M.2
-
9
-
-
58149251898
-
Late developmental plasticity in the T helper 17 lineage
-
Lee YK, Turner H, Maynard CL, Oliver JR, Chen D, et al. (2009) Late developmental plasticity in the T helper 17 lineage. Immunity 30: 92-107.
-
(2009)
Immunity
, vol.30
, pp. 92-107
-
-
Lee, Y.K.1
Turner, H.2
Maynard, C.L.3
Oliver, J.R.4
Chen, D.5
-
10
-
-
0032212793
-
Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism
-
Ouyang W, Ranganath SH, Weindel K, Bhattacharya D, Murphy TL, et al. (1998) Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism. Immunity 9: 745-755.
-
(1998)
Immunity
, vol.9
, pp. 745-755
-
-
Ouyang, W.1
Ranganath, S.H.2
Weindel, K.3
Bhattacharya, D.4
Murphy, T.L.5
-
11
-
-
77953917067
-
Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation
-
Wei L, Vahedi G, Sun HW, Watford WT, Takatori H, et al. (2010) Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation. Immunity 32: 840-851.
-
(2010)
Immunity
, vol.32
, pp. 840-851
-
-
Wei, L.1
Vahedi, G.2
Sun, H.W.3
Watford, W.T.4
Takatori, H.5
-
12
-
-
78149322622
-
STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells
-
Onodera A, Yamashita M, Endo Y, Kuwahara M, Tofukuji S, et al. (2010) STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells. J Exp Med 207: 2493-2506.
-
(2010)
J Exp Med
, vol.207
, pp. 2493-2506
-
-
Onodera, A.1
Yamashita, M.2
Endo, Y.3
Kuwahara, M.4
Tofukuji, S.5
-
14
-
-
33646196946
-
Regulation of Th2 differentiation and Il4 locus accessibility
-
Ansel KM, Djuretic I, Tanasa B, Rao A, (2006) Regulation of Th2 differentiation and Il4 locus accessibility. Annu Rev Immunol 24: 607-656.
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 607-656
-
-
Ansel, K.M.1
Djuretic, I.2
Tanasa, B.3
Rao, A.4
-
15
-
-
45449098427
-
Initiation and maintenance of Th2 cell identity
-
Nakayama T, Yamashita M, (2008) Initiation and maintenance of Th2 cell identity. Curr Opin Immunol 20: 265-271.
-
(2008)
Curr Opin Immunol
, vol.20
, pp. 265-271
-
-
Nakayama, T.1
Yamashita, M.2
-
16
-
-
0042432046
-
CD8 T cell-specific downregulation of histone hyperacetylation and gene activation of the IL-4 gene locus by ROG, repressor of GATA
-
Omori M, Yamashita M, Inami M, Ukai-Tadenuma M, Kimura M, et al. (2003) CD8 T cell-specific downregulation of histone hyperacetylation and gene activation of the IL-4 gene locus by ROG, repressor of GATA. Immunity 19: 281-294.
-
(2003)
Immunity
, vol.19
, pp. 281-294
-
-
Omori, M.1
Yamashita, M.2
Inami, M.3
Ukai-Tadenuma, M.4
Kimura, M.5
-
17
-
-
3042598052
-
Essential role of GATA3 for the maintenance of type 2 helper T (Th2) cytokine production and chromatin remodeling at the Th2 cytokine gene loci
-
Yamashita M, Ukai-Tadenuma M, Miyamoto T, Sugaya K, Hosokawa H, et al. (2004) Essential role of GATA3 for the maintenance of type 2 helper T (Th2) cytokine production and chromatin remodeling at the Th2 cytokine gene loci. J Biol Chem 279: 26983-26990.
-
(2004)
J Biol Chem
, vol.279
, pp. 26983-26990
-
-
Yamashita, M.1
Ukai-Tadenuma, M.2
Miyamoto, T.3
Sugaya, K.4
Hosokawa, H.5
-
18
-
-
2542480773
-
CD28 costimulation controls histone hyperacetylation of the interleukin 5 gene locus in developing th2 cells
-
Inami M, Yamashita M, Tenda Y, Hasegawa A, Kimura M, et al. (2004) CD28 costimulation controls histone hyperacetylation of the interleukin 5 gene locus in developing th2 cells. J Biol Chem 279: 23123-23133.
-
(2004)
J Biol Chem
, vol.279
, pp. 23123-23133
-
-
Inami, M.1
Yamashita, M.2
Tenda, Y.3
Hasegawa, A.4
Kimura, M.5
-
19
-
-
1242274405
-
GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells
-
Pai SY, Truitt ML, Ho IC, (2004) GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells. Proc Natl Acad Sci U S A 101: 1993-1998.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1993-1998
-
-
Pai, S.Y.1
Truitt, M.L.2
Ho, I.C.3
-
20
-
-
9244263631
-
Conditional deletion of Gata3 shows its essential function in TH1-TH2 responses
-
Zhu J, Min B, Hu-Li J, Watson CJ, Grinberg A, et al. (2004) Conditional deletion of Gata3 shows its essential function in TH1-TH2 responses. Nat Immunol 5: 1157-1165.
-
(2004)
Nat Immunol
, vol.5
, pp. 1157-1165
-
-
Zhu, J.1
Min, B.2
Hu-Li, J.3
Watson, C.J.4
Grinberg, A.5
-
21
-
-
80051885764
-
Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types
-
Wei G, Abraham BJ, Yagi R, Jothi R, Cui K, et al. (2011) Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types. Immunity 35: 299-311.
-
(2011)
Immunity
, vol.35
, pp. 299-311
-
-
Wei, G.1
Abraham, B.J.2
Yagi, R.3
Jothi, R.4
Cui, K.5
-
22
-
-
79958042030
-
Genome-wide analysis reveals unique regulation of transcription of Th2-specific genes by GATA3
-
Horiuchi S, Onodera A, Hosokawa H, Watanabe Y, Tanaka T, et al. (2011) Genome-wide analysis reveals unique regulation of transcription of Th2-specific genes by GATA3. J Immunol 186: 6378-6389.
-
(2011)
J Immunol
, vol.186
, pp. 6378-6389
-
-
Horiuchi, S.1
Onodera, A.2
Hosokawa, H.3
Watanabe, Y.4
Tanaka, T.5
-
23
-
-
33646586637
-
Crucial role of MLL for the maintenance of memory T helper type 2 cell responses
-
Yamashita M, Hirahara K, Shinnakasu R, Hosokawa H, Norikane S, et al. (2006) Crucial role of MLL for the maintenance of memory T helper type 2 cell responses. Immunity 24: 611-622.
-
(2006)
Immunity
, vol.24
, pp. 611-622
-
-
Yamashita, M.1
Hirahara, K.2
Shinnakasu, R.3
Hosokawa, H.4
Norikane, S.5
-
24
-
-
4544275712
-
Interleukin (IL)-4-independent maintenance of histone modification of the IL-4 gene loci in memory Th2 cells
-
Yamashita M, Shinnakasu R, Nigo Y, Kimura M, Hasegawa A, et al. (2004) Interleukin (IL)-4-independent maintenance of histone modification of the IL-4 gene loci in memory Th2 cells. J Biol Chem 279: 39454-39464.
-
(2004)
J Biol Chem
, vol.279
, pp. 39454-39464
-
-
Yamashita, M.1
Shinnakasu, R.2
Nigo, Y.3
Kimura, M.4
Hasegawa, A.5
-
25
-
-
58849104422
-
GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation
-
Ho IC, Tai TS, Pai SY, (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol 9: 125-135.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 125-135
-
-
Ho, I.C.1
Tai, T.S.2
Pai, S.Y.3
-
26
-
-
57649217417
-
Cyclic AMP-induced chromatin changes support the NFATc-mediated recruitment of GATA-3 to the interleukin 5 promoter
-
Klein-Hessling S, Bopp T, Jha MK, Schmidt A, Miyatake S, et al. (2008) Cyclic AMP-induced chromatin changes support the NFATc-mediated recruitment of GATA-3 to the interleukin 5 promoter. J Biol Chem 283: 31030-31037.
-
(2008)
J Biol Chem
, vol.283
, pp. 31030-31037
-
-
Klein-Hessling, S.1
Bopp, T.2
Jha, M.K.3
Schmidt, A.4
Miyatake, S.5
-
27
-
-
78751701435
-
The transcription factor STAT3 is required for T helper 2 cell development
-
Stritesky GL, Muthukrishnan R, Sehra S, Goswami R, Pham D, et al. (2011) The transcription factor STAT3 is required for T helper 2 cell development. Immunity 34: 39-49.
-
(2011)
Immunity
, vol.34
, pp. 39-49
-
-
Stritesky, G.L.1
Muthukrishnan, R.2
Sehra, S.3
Goswami, R.4
Pham, D.5
-
28
-
-
82055163110
-
A Critical Role for STAT3 Transcription Factor Signaling in the Development and Maintenance of Human T Cell Memory
-
Siegel AM, Heimall J, Freeman AF, Hsu AP, Brittain E, et al. (2011) A Critical Role for STAT3 Transcription Factor Signaling in the Development and Maintenance of Human T Cell Memory. Immunity 35: 806-818.
-
(2011)
Immunity
, vol.35
, pp. 806-818
-
-
Siegel, A.M.1
Heimall, J.2
Freeman, A.F.3
Hsu, A.P.4
Brittain, E.5
-
29
-
-
75549087056
-
Disease-associated functions of IL-33: the new kid in the IL-1 family
-
Liew FY, Pitman NI, McInnes IB, (2010) Disease-associated functions of IL-33: the new kid in the IL-1 family. Nat Rev Immunol 10: 103-110.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 103-110
-
-
Liew, F.Y.1
Pitman, N.I.2
McInnes, I.B.3
-
30
-
-
77951817855
-
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
-
Neill DR, Wong SH, Bellosi A, Flynn RJ, Daly M, et al. (2010) Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. Nature 464: 1367-1370.
-
(2010)
Nature
, vol.464
, pp. 1367-1370
-
-
Neill, D.R.1
Wong, S.H.2
Bellosi, A.3
Flynn, R.J.4
Daly, M.5
-
31
-
-
75749122181
-
Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells
-
Moro K, Yamada T, Tanabe M, Takeuchi T, Ikawa T, et al. (2010) Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells. Nature 463: 540-544.
-
(2010)
Nature
, vol.463
, pp. 540-544
-
-
Moro, K.1
Yamada, T.2
Tanabe, M.3
Takeuchi, T.4
Ikawa, T.5
-
32
-
-
47249139528
-
Inhibition of the lymphotoxin pathway as a therapy for autoimmune disease
-
Browning JL, (2008) Inhibition of the lymphotoxin pathway as a therapy for autoimmune disease. Immunol Rev 223: 202-220.
-
(2008)
Immunol Rev
, vol.223
, pp. 202-220
-
-
Browning, J.L.1
-
33
-
-
80355146868
-
Monocyte recruitment during infection and inflammation
-
Shi C, Pamer EG, (2011) Monocyte recruitment during infection and inflammation. Nat Rev Immunol 11: 762-774.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 762-774
-
-
Shi, C.1
Pamer, E.G.2
|