The papain-like protease of porcine epidemic diarrhea virus negatively regulates type I interferon pathway by acting as a viral deubiquitinase

Journal of General Virology

Volumn 94, Issue PART7, 2013, Pages 1554-1567

  Xing, Yaling ^a,b   Chen, Jianfei ^a   Tu, Jian ^c   Zhang, Bailing ^b   Chen, Xiaojuan ^b   Shi, Hongyan ^a   Baker, Susan C ^d   Feng, Li ^a   Chen, Zhongbin ^b  

^a INSTITUTE OF PLANT PROTECTION   (China)

^b BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^c MACQUARIE UNIVERSITY   (Australia)

^d LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; DOUBLE STRANDED RNA; INTERFERON; INTERFERON REGULATORY FACTOR 3; PAPAIN; PAPAIN LIKE PROTEASE 2; POLYINOSINIC POLYCYTIDYLIC ACID; PORCINE EPIDEMIC DIARRHEA VIRUS PAPAIN LIKE PROTEASE 2; PROTEINASE; PROTEINASE INHIBITOR; RETINOIC ACID INDUCIBLE PROTEIN I; UBIQUITIN; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONTROLLED STUDY; CYTOKINE RELEASE; IMMUNE RESPONSE; IMMUNOPRECIPITATION; INTERFERON PRODUCTION; OPEN READING FRAME; PORCINE EPIDEMIC DIARRHEA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UBIQUITINATION;

ANIMALS; CERCOPITHECUS AETHIOPS; ENDOPEPTIDASES; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; IMMUNITY, INNATE; INTERFERON TYPE I; INTERFERON-BETA; PAPAIN; PORCINE EPIDEMIC DIARRHEA VIRUS; SIGNAL TRANSDUCTION; SWINE; UBIQUITIN; VERO CELLS;

PORCINE EPIDEMIC DIARRHEA VIRUS; SUIDAE;

EID: 84879142678     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.051169-0     Document Type: Article

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