The flow dependency of Tie2 expression in endotoxemia

Intensive Care Medicine

Volumn 39, Issue 7, 2013, Pages 1262-1271

  Kurniati, Neng F ^a,d   Jongman, Rianne M ^a   Vom Hagen, Franziska ^b   Spokes, Katherine C ^c   Moser, Jill ^a   Regan, Erzsébet Ravasz ^c   Krenning, Guido ^a   Moonen, Jan Renier A J ^a   Harmsen, Martin C ^a   Struys, Michel M R F ^a   Hammes, Hans Peter ^b   Zijlstra, Jan G ^a   Aird, William C ^c   Heeringa, Peter ^a   Molema, Grietje ^a   Van Meurs, Matijs ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c HARVARD MEDICAL SCHOOL   (United States)

^d BANDUNG INSTITUTE OF TECHNOLOGY   (Indonesia)

Author keywords

Endothelial Tie2; Flow; In vitro; In vivo; Lipopolysaccharide

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; ANGIOPOIETIN RECEPTOR; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; ENDOTOXEMIA; HEMORRHAGIC SHOCK; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN DEPLETION; PROTEIN EXPRESSION; SHEAR STRESS;

ANIMALS; CAPILLARY PERMEABILITY; CELLS, CULTURED; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; ENDOTOXEMIA; HUMANS; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED C57BL; NF-KAPPA B; NITRILES; PREMEDICATION; RECEPTOR, TIE-2; RNA, MESSENGER; SHOCK, HEMORRHAGIC; SIGNAL TRANSDUCTION; SULFONES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84879115058     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-013-2899-7     Document Type: Article

References (33)

1. Doi K, Leelahavanichkul A, Yuen PS, Star RA (2009) Animal models of sepsis and sepsis-induced kidney injury. J Clin Invest 119(10):2868-2878
2. Dauphinee SM, Karsan A (2006) Lipopolysaccharide signaling in endothelial cells. Lab Invest 86(1):9-22
3. Kim DH, Jung YJ, Lee AS, Lee S, Kang KP, Lee TH et al (2009) COMP-Angiopoietin-1 decreases lipopolysaccharide-induced acute kidney injury. Kidney Int 76:1180-1191
4. Liu SF, Ye X, Malik AB (1997) In vivo inhibition of nuclear factor-kappa B activation prevents inducible nitric oxide synthase expression and systemic hypotension in a rat model of septic shock. J Immunol 159(8):3976-3983
5. Pries AR, Secomb TW, Gaehtgens P (1995) Design principles of vascular beds. Circ Res 77(5):1017-1023
6. Nayak L, Lin Z, Jain MK (2011) "Go with the flow": how Kruppel-like factor 2 regulates the vasoprotective effects of shear stress. Antioxid Redox Signal 15(5):1449-1461
7. van Meurs M, Kumpers P, Ligtenberg JJ, Meertens JH, Molema G, Zijlstra JG (2009) Bench-to-bedside review: angiopoietin signalling in critical illness - a future target? Crit Care 13(2):207
8. Wong AL, Haroon ZA, Werner S, Dewhirst MW, Greenberg CS, Peters KG (1997) Tie2 expression and phosphorylation in angiogenic and quiescent adult tissues. Circ Res 81(4):567-574
9. van Meurs M, Kurniati NF, Wulfert FM, Asgeirsdottir SA, de Graaf I, Satchell SC et al (2009) Shock-induced stress induces loss of microvascular endothelial Tie2 in the kidney which is not associated with reduced glomerular barrier function. Am J Physiol Renal Physiol 297(2):F272-F281
10. Hegeman MA, Hennus MP, van Meurs M, Cobelens PM, Kavelaars A, Jansen NJ et al (2010) Angiopoietin-1 treatment reduces inflammation but does not prevent ventilator-induced lung injury. PLoS ONE 5(12):e15653
11. David S, Ghosh CC, Kuempers P, Shushakova N, Van SP, Khankin EV et al (2011) Effects of a synthetic PEG-ylated Tie-2 agonist peptide on endotoxemic lung injury and mortality. Am J Physiol Lung Cell Mol Physiol 300:L851-L862
12. David S, Park JK, van Meurs M, Zijlstra JG, Koenecke C, Schrimpf C et al (2011) Acute administration of recombinant Angiopoietin-1 ameliorates multiple-organ dysfunction syndrome and improves survival in murine sepsis. Cytokine 55(2):251-259
13. Satchell SC, Tasman CH, Singh A, Ni L, Geelen J, von Ruhland CJ et al (2006) Conditionally immortalized human glomerular endothelial cells expressing fenestrations in response to VEGF. Kidney Int 69(9):1633-1640
14. Kuldo JM, Ogawara KI, Werner N, Asgeirsdottir SA, Kamps JA, Kok RJ et al (2005) Molecular pathways of endothelial cell activation for (targeted) pharmacological intervention of chronic inflammatory diseases. Curr Vasc Pharmacol 3(1):11-39
15. Jin E, Liu J, Suehiro J, Yuan L, Okada Y, Nikolova-Krstevski V et al (2009) Differential roles for ETS, CREB, and EGR binding sites in mediating VEGF receptor 1 expression in vivo. Blood 114(27):5557-5566
16. van Meurs M, Wulfert FM, Knol AJ, de Haes A, Houwertjes M, Aarts LP et al (2008) Early organ-specific endothelial activation during hemorrhagic shock and resuscitation. Shock 29(2):291-299
17. Atkins GB, Jain M (2007) Role of kruppel-like transcription factors in endothelial biology. Circ Res 100(12):1686-1695
18. Hay DC, Beers C, Cameron V, Thomson L, Flitney FW, Hay RT (2003) Activation of NF-kappaB nuclear transcription factor by flow in human endothelial cells. Biochim Biophys Acta 1642(1-2):33-44
19. Mohan S, Koyoma K, Thangasamy A, Nakano H, Glickman RD, Mohan N (2007) Low shear stress preferentially enhances IKK activity through selective sources of ROS for persistent activation of NF-kappaB in endothelial cells. Am J Physiol Cell Physiol 292(1):C362-C371
20. Wada Y, Otu H, Wu S, Abid MR, Okada H, Libermann T et al (2005) Preconditioning of primary human endothelial cells with inflammatory mediators alters the "set point" of the cell. FASEB J 19(13):1914-1916
21. De Backer D, Donadello K, Taccone FS, Ospina-Tascon G, Salgado D, Vincent JL (2011) Microcirculatory alterations: potential mechanisms and implications for therapy. Ann Intensive Care 1(1):27
22. Molema G, Aird WC (2012) Vascular heterogeneity in the kidney. Semin Nephrol 32(2):145-155
23. Bogdanovic E, Nguyen VP, Dumont DJ (2006) Activation of Tie2 by angiopoietin-1 and angiopoietin-2 results in their release and receptor internalization. J Cell Sci 119(Pt 17):3551-3560
24. Blackwell TS, Christman JW (1996) Sepsis and cytokines: current status. Br J Anaesth 77(1):110-117
25. Willam C, Koehne P, Jurgensen JS, Grafe M, Wagner KD, Bachmann S et al (2000) Tie2 receptor expression is stimulated by hypoxia and proinflammatory cytokines in human endothelial cells. Circ Res 87(5):370-377
26. Takagi H, Koyama S, Seike H, Oh H, Otani A, Matsumura M et al (2003) Potential role of the angiopoietin/tie2 system in ischemia-induced retinal neovascularization. Invest Ophthalmol Vis Sci 44(1):393-402
27. Park SW, Chen SW, Kim M, Brown KM, Kolls JK, D'Agati VD et al (2011) Cytokines induce small intestine and liver injury after renal ischemia or nephrectomy. Lab Invest 91(1):63-84
28. Gardiner SM, Kemp PA, March JE, Woolley J, Bennett T (1998) The influence of antibodies to TNF-alpha and IL-1beta on haemodynamic responses to the cytokines, and to lipopolysaccharide, in conscious rats. Br J Pharmacol 125(7):1543-1550
29. Morimatsu H, Ishikawa K, May CN, Bailey M, Bellomo R (2012) The systemic and regional hemodynamic effects of phenylephrine in sheep under normal conditions and during early hyperdynamic sepsis. Anesth Analg 115(2):330-342
30. Tran M, Tam D, Bardia A, Bhasin M, Rowe GC, Kher A et al (2011) PGC-1alpha promotes recovery after acute kidney injury during systemic inflammation in mice. J Clin Invest 121:4003-4014
31. Ellis CG, Bateman RM, Sharpe MD, Sibbald WJ, Gill R (2002) Effect of a maldistribution of microvascular blood flow on capillary O(2) extraction in sepsis. Am J Physiol Heart Circ Physiol 282(1):H156-H164
32. Ye X, Ding J, Zhou X, Chen G, Liu SF (2008) Divergent roles of endothelial NF-kappaB in multiple organ injury and bacterial clearance in mouse models of sepsis. J Exp Med 205(6):1303-1315
33. Adrian JE, Morselt HW, Suss R, Barnert S, Kok JW, Asgeirsdottir SA et al (2010) Targeted SAINT-O-Somes for improved intracellular delivery of siRNA and cytotoxic drugs into endothelial cells. J Control Release 144(3):341-349