Mineralocorticoid receptor agonists induce mouse aortic aneurysm formation and rupture in the presence of high salt

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 33, Issue 7, 2013, Pages 1568-1579

  Liu, Shu ^a   Xie, Zhongwen ^a   Daugherty, Alan ^a,b,d   Cassis, Lisa A ^b,c   Pearson, Kevin J ^b   Gong, Ming C ^a,b   Guo, Zhenheng ^a,b,d  

^a Graduate Center for Nutritional Sciences   (United States)

^b 509 Wethington Bldg ^*  (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

^d UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Aldosterone; Aneurysm; Desoxycorticosterone; Receptors; Salt

Indexed keywords

ALDOSTERONE; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; DEOXYCORTICOSTERONE ACETATE; ELASTIN; ENALAPRIL; EPLERENONE; LOSARTAN; SODIUM CHLORIDE; SPIRONOLACTONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA ANEURYSM; AORTA RUPTURE; APOPTOSIS; ARTICLE; BLOOD PRESSURE; C57BL 6 MOUSE; CELL DEGENERATION; CELL INFILTRATION; CONTROLLED STUDY; INFLAMMATORY CELL; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; SMOOTH MUSCLE FIBER;

ALDOSTERONE; ANEURYSM; DESOXYCORTICOSTERONE; RECEPTORS; SALT;

ALDOSTERONE; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; AORTA; AORTIC ANEURYSM, ABDOMINAL; AORTIC ANEURYSM, THORACIC; AORTIC RUPTURE; APOPTOSIS; BLOOD PRESSURE; DESOXYCORTICOSTERONE; DISEASE MODELS, ANIMAL; ELASTIN; ENALAPRIL; LOSARTAN; MALE; MICE; MICE, INBRED C57BL; MINERALOCORTICOID RECEPTOR ANTAGONISTS; MUSCLE, SMOOTH, VASCULAR; OXIDATIVE STRESS; RECEPTORS, MINERALOCORTICOID; SODIUM CHLORIDE, DIETARY; SPIRONOLACTONE; TIME FACTORS;

EID: 84879107059     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.112.300820     Document Type: Article

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