Transient exposure of neonatal female mice to testosterone abrogates the sexual dimorphism of abdominal aortic aneurysms

Circulation Research

Volumn 110, Issue 11, 2012, Pages

  Zhang, Xuan ^a   Thatcher, Sean E ^a   Rateri, Debra L ^b   Bruemmer, Dennis ^b   Charnigo, Richard ^a   Daugherty, Alan ^a,b   Cassis, Lisa A ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

aneurysm; angiotensin; sexual dimorphism; testosterone; vascular smooth muscle

Indexed keywords

ANGIOTENSIN 1A RECEPTOR; ANGIOTENSIN II; HYDROGEN PEROXIDE; MESSENGER RNA; TESTOSTERONE; TESTOSTERONE PROPIONATE;

ABDOMINAL AORTA ANEURYSM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ANEURYSM; ARTICLE; ATHEROSCLEROSIS; CELL CULTURE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DRUG EFFECT; FEMALE; HYPERCHOLESTEROLEMIA; MALE; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RISK FACTOR; SEX DIFFERENCE; SMOOTH MUSCLE FIBER; TESTOSTERONE BLOOD LEVEL;

AGE FACTORS; ANGIOTENSIN II; ANIMALS; ANIMALS, NEWBORN; AORTA, ABDOMINAL; AORTIC ANEURYSM, ABDOMINAL; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CELLS, CULTURED; FEMALE; HYDROGEN PEROXIDE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTORS, LDL; RISK FACTORS; RNA, MESSENGER; SEX CHARACTERISTICS; SEX FACTORS; TESTOSTERONE PROPIONATE; UP-REGULATION;

EID: 84861634267     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.111.253880     Document Type: Article

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