메뉴 건너뛰기




Volumn 48, Issue 6, 2013, Pages 859-864

Frequency of CD4+ FOXP3+ regulatory T-cells at early stages after HLA-mismatched allogeneic hematopoietic SCT predicts the incidence of acute GVHD

Author keywords

allogeneic SCT; GVHD; HLA mismatch; regulatory T cells

Indexed keywords

CD4 ANTIGEN; TRANSCRIPTION FACTOR FOXP3;

EID: 84879069945     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/bmt.2012.232     Document Type: Article
Times cited : (38)

References (39)
  • 1
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995; 155: 1151-1164.
    • (1995) J Immunol , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 3
    • 0037093217 scopus 로고    scopus 로고
    • The infusion of ex vivo activated and expanded CD4(\+)CD25(\+) immune regulatory cells inhibits graft-versus-host disease lethality
    • Taylor PA, Lees CJ, Blazar BR. The infusion of ex vivo activated and expanded CD4(\+)CD25(\+) immune regulatory cells inhibits graft-versus-host disease lethality. Blood 2002; 99: 3493-3499.
    • (2002) Blood , vol.99 , pp. 3493-3499
    • Taylor, P.A.1    Lees, C.J.2    Blazar, B.R.3
  • 4
    • 0037025943 scopus 로고    scopus 로고
    • Donor-type CD4(\+)CD25(\+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation
    • Hoffmann P, Ermann J, Edinger M, Fathman CG, Strober S. Donor-type CD4(\+)CD25(\+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation. J Exp Med 2002; 196: 389-399.
    • (2002) J Exp Med , vol.196 , pp. 389-399
    • Hoffmann, P.1    Ermann, J.2    Edinger, M.3    Fathman, C.G.4    Strober, S.5
  • 5
    • 0037026001 scopus 로고    scopus 로고
    • CD4(\+)CD25(\+) immunoregulatory T cells: New therapeutics for graft-versus-host disease
    • Cohen JL, Trenado A, Vasey D, Klatzmann D, Salomon BL. CD4(\+)CD25(\+) immunoregulatory T cells: new therapeutics for graft-versus-host disease. J Exp Med 2002; 196: 401-406.
    • (2002) J Exp Med , vol.196 , pp. 401-406
    • Cohen, J.L.1    Trenado, A.2    Vasey, D.3    Klatzmann, D.4    Salomon, B.L.5
  • 6
    • 27144500976 scopus 로고    scopus 로고
    • Reduced frequency of FOXP3\+ CD4\+CD25\+ regulatory T cells in patients with chronic graft-versus-host disease
    • Zorn E, Kim HT, Lee SJ, Floyd BH, Litsa D, Arumugarajah S et al. Reduced frequency of FOXP3\+ CD4\+CD25\+ regulatory T cells in patients with chronic graft-versus-host disease. Blood 2005; 106: 2903-2911.
    • (2005) Blood , vol.106 , pp. 2903-2911
    • Zorn, E.1    Kim, H.T.2    Lee, S.J.3    Floyd, B.H.4    Litsa, D.5    Arumugarajah, S.6
  • 7
    • 22144444577 scopus 로고    scopus 로고
    • Numbers of Foxp3-expressing CD4\+CD25high T cells do not correlate with the establishment of long-term tolerance after allogeneic stem cell transplantation
    • Meignin V, Peffault de Latour R, Zuber J, Regnault A, Mounier N, Lemaitre F et al. Numbers of Foxp3-expressing CD4\+CD25high T cells do not correlate with the establishment of long-term tolerance after allogeneic stem cell transplantation. Exp Hematol 2005; 33: 894-900.
    • (2005) Exp Hematol , vol.33 , pp. 894-900
    • Meignin, V.1    Peffault De Latour, R.2    Zuber, J.3    Regnault, A.4    Mounier, N.5    Lemaitre, F.6
  • 8
    • 4544268251 scopus 로고    scopus 로고
    • Kinetic of regulatory CD25high and activated CD134\+ (OX40) T lymphocytes during acute and chronic graft-versus-host disease after allogeneic bone marrow transplantation
    • Sanchez J, Casano J, Alvarez MA, Roman-Gomez J, Martin C, Martinez F et al. Kinetic of regulatory CD25high and activated CD134\+ (OX40) T lymphocytes during acute and chronic graft-versus-host disease after allogeneic bone marrow transplantation. Br J Haematol 2004; 126: 697-703.
    • (2004) Br J Haematol , vol.126 , pp. 697-703
    • Sanchez, J.1    Casano, J.2    Alvarez, M.A.3    Roman-Gomez, J.4    Martin, C.5    Martinez, F.6
  • 9
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003; 299: 1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 10
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4\+CD25\+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4\+CD25\+ regulatory T cells. Nat Immunol 2003; 4: 330-336.
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 11
    • 33746809277 scopus 로고    scopus 로고
    • High donor FOXP3-positive regulatory T-cell (Treg) content is associated with a low risk of GVHD following HLA-matched allogeneic SCT
    • Rezvani K, Mielke S, Ahmadzadeh M, Kilical Y, Savani BN, Zeilah J et al. High donor FOXP3-positive regulatory T-cell (Treg) content is associated with a low risk of GVHD following HLA-matched allogeneic SCT. Blood 2006; 108: 1291-1297.
    • (2006) Blood , vol.108 , pp. 1291-1297
    • Rezvani, K.1    Mielke, S.2    Ahmadzadeh, M.3    Kilical, Y.4    Savani, B.N.5    Zeilah, J.6
  • 12
    • 34047215247 scopus 로고    scopus 로고
    • Correlation of the CD4\+CD25high T-regulatory cells in recipients and their corresponding donors to acute GVHD
    • Zhai Z, Sun Z, Li Q, Zhang A, Liu H, Xu J et al. Correlation of the CD4\+CD25high T-regulatory cells in recipients and their corresponding donors to acute GVHD. Transpl Int 2007; 20: 440-446.
    • (2007) Transpl Int , vol.20 , pp. 440-446
    • Zhai, Z.1    Sun, Z.2    Li, Q.3    Zhang, A.4    Liu, H.5    Xu, J.6
  • 13
    • 77953613618 scopus 로고    scopus 로고
    • Frequency of CD4(\+)CD25(hi)FOXP3(\+) regulatory T cells has diagnostic and prognostic value as a biomarker for acute graft-versus-host-disease
    • Magenau JM, Qin X, Tawara I, Rogers CE, Kitko C, Schlough M et al. Frequency of CD4(\+)CD25(hi)FOXP3(\+) regulatory T cells has diagnostic and prognostic value as a biomarker for acute graft-versus-host-disease. Biol Blood Marrow Transplant 2010; 16: 907-914.
    • (2010) Biol Blood Marrow Transplant , vol.16 , pp. 907-914
    • Magenau, J.M.1    Qin, X.2    Tawara, I.3    Rogers, C.E.4    Kitko, C.5    Schlough, M.6
  • 15
    • 0142182235 scopus 로고    scopus 로고
    • Successful engraftment of HLA-haploidentical related transplants using nonmyeloablative conditioning with fludarabine, busulfan and anti-T-lymphocyte globulin
    • Tamaki H, Ikegame K, Kawakami M, Fujioka T, Tsuboi A, Oji Y et al. Successful engraftment of HLA-haploidentical related transplants using nonmyeloablative conditioning with fludarabine, busulfan and anti-T-lymphocyte globulin. Leukemia 2003; 17: 2052-2054.
    • (2003) Leukemia , vol.17 , pp. 2052-2054
    • Tamaki, H.1    Ikegame, K.2    Kawakami, M.3    Fujioka, T.4    Tsuboi, A.5    Oji, Y.6
  • 16
    • 37249030518 scopus 로고    scopus 로고
    • Unmanipulated HLA 2-3 antigen-mismatched (haploidentical) bone marrow transplantation using only pharmacological GVHD prophylaxis
    • Ogawa H, Ikegame K, Kaida K, Yoshihara S, Fujioka T, Taniguchi Y et al. Unmanipulated HLA 2-3 antigen-mismatched (haploidentical) bone marrow transplantation using only pharmacological GVHD prophylaxis. Exp Hematol 2008; 36: 1-8.
    • (2008) Exp Hematol , vol.36 , pp. 1-8
    • Ogawa, H.1    Ikegame, K.2    Kaida, K.3    Yoshihara, S.4    Fujioka, T.5    Taniguchi, Y.6
  • 17
    • 34548559241 scopus 로고    scopus 로고
    • Unmanipulated HLA 2-3 antigen-mismatched (haploidentical) stem cell transplantation using nonmyeloablative conditioning
    • Ogawa H, Ikegame K, Yoshihara S, Kawakami M, Fujioka T, Masuda T et al. Unmanipulated HLA 2-3 antigen-mismatched (haploidentical) stem cell transplantation using nonmyeloablative conditioning. Biol Blood Marrow Transplant 2006; 12: 1073-1084.
    • (2006) Biol Blood Marrow Transplant , vol.12 , pp. 1073-1084
    • Ogawa, H.1    Ikegame, K.2    Yoshihara, S.3    Kawakami, M.4    Fujioka, T.5    Masuda, T.6
  • 18
    • 0016187133 scopus 로고
    • Clinical manifestations of graft-versus-host disease in human recipients of marrow from HL-A-matched sibling donors
    • Glucksberg H, Storb R, Fefer A, Buckner CD, Neiman PE, Clift RA et al. Clinical manifestations of graft-versus-host disease in human recipients of marrow from HL-A-matched sibling donors. Transplantation 1974; 18: 295-304.
    • (1974) Transplantation , vol.18 , pp. 295-304
    • Glucksberg, H.1    Storb, R.2    Fefer, A.3    Buckner, C.D.4    Neiman, P.E.5    Clift, R.A.6
  • 20
    • 33847629730 scopus 로고    scopus 로고
    • FOXP3 expression in peripheral blood rapidly recovers and lacks correlation with the occurrence of graft-versus-host disease after allogeneic stem cell transplantation
    • Arimoto K, Kadowaki N, Ishikawa T, Ichinohe T, Uchiyama T. FOXP3 expression in peripheral blood rapidly recovers and lacks correlation with the occurrence of graft-versus-host disease after allogeneic stem cell transplantation. Int J Hematol 2007; 85: 154-162.
    • (2007) Int J Hematol , vol.85 , pp. 154-162
    • Arimoto, K.1    Kadowaki, N.2    Ishikawa, T.3    Ichinohe, T.4    Uchiyama, T.5
  • 22
    • 16844362608 scopus 로고    scopus 로고
    • Mechanisms of suppression by suppressor T cells
    • von Boehmer H. Mechanisms of suppression by suppressor T cells. Nat Immunol 2005; 6: 338-344.
    • (2005) Nat Immunol , vol.6 , pp. 338-344
    • Von Boehmer, H.1
  • 23
    • 40049109392 scopus 로고    scopus 로고
    • Biological advances in acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
    • Duran-Struuck R, Reddy P. Biological advances in acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. Transplantation 2008; 85: 303-308.
    • (2008) Transplantation , vol.85 , pp. 303-308
    • Duran-Struuck, R.1    Reddy, P.2
  • 24
    • 51649121552 scopus 로고    scopus 로고
    • Change in plasma tumor necrosis factor receptor 1 levels in the first week after myeloablative allogeneic transplantation correlates with severity and incidence of GVHD and survival
    • Choi SW, Kitko CL, Braun T, Paczesny S, Yanik G, Mineishi S et al. Change in plasma tumor necrosis factor receptor 1 levels in the first week after myeloablative allogeneic transplantation correlates with severity and incidence of GVHD and survival. Blood 2008; 112: 1539-1542.
    • (2008) Blood , vol.112 , pp. 1539-1542
    • Choi, S.W.1    Kitko, C.L.2    Braun, T.3    Paczesny, S.4    Yanik, G.5    Mineishi, S.6
  • 25
    • 77956492054 scopus 로고    scopus 로고
    • Elevations of tumor necrosis factor receptor 1 at day 7 and acute graft-versus-host disease after allogeneic hematopoietic cell transplantation with nonmyeloablative conditioning
    • Willems E, Humblet-Baron S, Dengis O, Seidel L, Beguin Y, Baron F. Elevations of tumor necrosis factor receptor 1 at day 7 and acute graft-versus-host disease after allogeneic hematopoietic cell transplantation with nonmyeloablative conditioning. Bone Marrow Transplant 2010; 45: 1442-1448.
    • (2010) Bone Marrow Transplant , vol.45 , pp. 1442-1448
    • Willems, E.1    Humblet-Baron, S.2    Dengis, O.3    Seidel, L.4    Beguin, Y.5    Baron, F.6
  • 27
    • 0032533897 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha production to lipopolysaccharide stimulation by donor cells predicts the severity of experimental acute graft-versus-host disease
    • Cooke KR, Hill GR, Crawford JM, Bungard D, Brinson YS, Delmonte Jr J et al. Tumor necrosis factor-alpha production to lipopolysaccharide stimulation by donor cells predicts the severity of experimental acute graft-versus-host disease. J Clin Invest 1998; 102: 1882-1891.
    • (1998) J Clin Invest , vol.102 , pp. 1882-1891
    • Cooke, K.R.1    Hill, G.R.2    Crawford, J.M.3    Bungard, D.4    Brinson, Y.S.5    Delmonte Jr., J.6
  • 28
    • 0030750397 scopus 로고    scopus 로고
    • Delaying transplantation after total body irradiation is a simple and effective way to reduce acute graft-versus-host disease mortality after major H2 incompatible transplantation
    • Xun CQ, Tsuchida M, Thompson JS. Delaying transplantation after total body irradiation is a simple and effective way to reduce acute graft-versus-host disease mortality after major H2 incompatible transplantation. Transplantation 1997; 64: 297-302.
    • (1997) Transplantation , vol.64 , pp. 297-302
    • Xun, C.Q.1    Tsuchida, M.2    Thompson, J.S.3
  • 29
    • 0030744503 scopus 로고    scopus 로고
    • Effect of sublethal total body irradiation on acute graft-versus-host disease and graftversus-leukemia effect in SCID mice
    • Sakai R, Maruta A, Yanoma S, Shimizu A, Harada M, Nakamura Y et al. Effect of sublethal total body irradiation on acute graft-versus-host disease and graftversus-leukemia effect in SCID mice. Bone Marrow Transplant 1997; 20: 183-189.
    • (1997) Bone Marrow Transplant , vol.20 , pp. 183-189
    • Sakai, R.1    Maruta, A.2    Yanoma, S.3    Shimizu, A.4    Harada, M.5    Nakamura, Y.6
  • 30
    • 0026573134 scopus 로고
    • Macrophage priming and lipopolysaccharide-triggered release of tumor necrosis factor alpha during graft-versushost disease
    • Nestel FP, Price KS, Seemayer TA, Lapp WS. Macrophage priming and lipopolysaccharide-triggered release of tumor necrosis factor alpha during graft-versushost disease. J Exp Med 1992; 175: 405-413.
    • (1992) J Exp Med , vol.175 , pp. 405-413
    • Nestel, F.P.1    Price, K.S.2    Seemayer, T.A.3    Lapp, W.S.4
  • 31
    • 33750905870 scopus 로고    scopus 로고
    • The initial phase of graft-versus-host disease is associated with a decrease of CD4\+CD25\+ regulatory T cells in the peripheral blood of patients after allogeneic stem cell transplantation
    • Schneider M, Munder M, Karakhanova S, Ho AD, Goerner M. The initial phase of graft-versus-host disease is associated with a decrease of CD4\+CD25\+ regulatory T cells in the peripheral blood of patients after allogeneic stem cell transplantation. Clin Lab Haematol 2006; 28: 382-390.
    • (2006) Clin Lab Haematol , vol.28 , pp. 382-390
    • Schneider, M.1    Munder, M.2    Karakhanova, S.3    Ho, A.D.4    Goerner, M.5
  • 32
    • 0022185980 scopus 로고
    • Surface markers of T cells causing lethal graft-vs-host disease to class i vs class II H-2 differences
    • Korngold R, Sprent J. Surface markers of T cells causing lethal graft-vs-host disease to class I vs class II H-2 differences. J Immunol 1985; 135: 3004-3010.
    • (1985) J Immunol , vol.135 , pp. 3004-3010
    • Korngold, R.1    Sprent, J.2
  • 33
    • 23044472871 scopus 로고    scopus 로고
    • In vivo analyses of early events in acute graft-versus-host disease reveal sequential infiltration of T-cell subsets
    • Beilhack A, Schulz S, Baker J, Beilhack GF, Wieland CB, Herman EI et al. In vivo analyses of early events in acute graft-versus-host disease reveal sequential infiltration of T-cell subsets. Blood 2005; 106: 1113-1122.
    • (2005) Blood , vol.106 , pp. 1113-1122
    • Beilhack, A.1    Schulz, S.2    Baker, J.3    Beilhack, G.F.4    Wieland, C.B.5    Herman, E.I.6
  • 34
    • 33845805735 scopus 로고    scopus 로고
    • Donor CD4\+T-cell production of tumor necrosis factor alpha significantly contributes to the early proinflammatory events of graft-versus-host disease
    • Ewing P, Miklos S, Olkiewicz KM, Muller G, Andreesen R, Holler E et al. Donor CD4\+T-cell production of tumor necrosis factor alpha significantly contributes to the early proinflammatory events of graft-versus-host disease. Exp Hematol 2007; 35: 155-163.
    • (2007) Exp Hematol , vol.35 , pp. 155-163
    • Ewing, P.1    Miklos, S.2    Olkiewicz, K.M.3    Muller, G.4    Andreesen, R.5    Holler, E.6
  • 35
    • 33644848095 scopus 로고    scopus 로고
    • Alloantigen affinity and CD4 help determine severity of graft-versus-host disease mediated by CD8 donor T cells
    • Yu XZ, Albert MH, Anasetti C. Alloantigen affinity and CD4 help determine severity of graft-versus-host disease mediated by CD8 donor T cells. J Immunol 2006; 176: 3383-3390.
    • (2006) J Immunol , vol.176 , pp. 3383-3390
    • Yu, X.Z.1    Albert, M.H.2    Anasetti, C.3
  • 37
    • 33645067654 scopus 로고    scopus 로고
    • Regulatory T cells inhibit stable contacts between CD4\+T cells and dendritic cells in vivo
    • Tadokoro CE, Shakhar G, Shen S, Ding Y, Lino AC, Maraver A et al. Regulatory T cells inhibit stable contacts between CD4\+T cells and dendritic cells in vivo. J Exp Med 2006; 203: 505-511.
    • (2006) J Exp Med , vol.203 , pp. 505-511
    • Tadokoro, C.E.1    Shakhar, G.2    Shen, S.3    Ding, Y.4    Lino, A.C.5    Maraver, A.6
  • 38
    • 84863017222 scopus 로고    scopus 로고
    • Cutting edge: Regulatory T cells selectively attenuate, not terminate, T cell signaling by disrupting NF-kappaB nuclear accumulation in CD4 T cells
    • Huang YH, Sojka DK, Fowell DJ. Cutting edge: regulatory T cells selectively attenuate, not terminate, T cell signaling by disrupting NF-kappaB nuclear accumulation in CD4 T cells. J Immunol 2012; 188: 947-951.
    • (2012) J Immunol , vol.188 , pp. 947-951
    • Huang, Y.H.1    Sojka, D.K.2    Fowell, D.J.3
  • 39
    • 79953809817 scopus 로고    scopus 로고
    • Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation
    • Di Ianni M, Falzetti F, Carotti A, Terenzi A, Castellino F, Bonifacio E et al. Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation. Blood 2011; 117: 3921-3928.
    • (2011) Blood , vol.117 , pp. 3921-3928
    • Di Ianni, M.1    Falzetti, F.2    Carotti, A.3    Terenzi, A.4    Castellino, F.5    Bonifacio, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.