Monitoring the interaction between β2-microglobulin and the molecular chaperone αB-crystallin by NMR and mass spectrometry: αB-crystallin dissociates β2-microglobulin oligomers

Journal of Biological Chemistry

Volumn 288, Issue 24, 2013, Pages 17844-17858

  Esposito, Gennaro ^a   Garvey, Megan ^b,g   Alverdi, Vera ^a,h   Pettirossi, Fabio ^a   Corazza, Alessandra ^a   Fogolari, Federico ^a   Polano, Maurizio ^a   Mangione, P Patrizia ^c,d   Giorgetti, Sofia ^c   Stoppini, Monica ^c   Rekas, Agata ^e   Bellotti, Vittorio ^c,d   Heck, Albert J R ^f   Carver, John A ^b  

^a UNIVERSITY OF UDINE   (Italy)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c UNIVERSITY OF PAVIA   (Italy)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION   (Australia)

^f UTRECHT UNIVERSITY   (Netherlands)

^g RWTH AACHEN UNIVERSITY   (Germany)

^h UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID FIBRIL FORMATION; COEFFICIENT MEASUREMENT; FIBRIL FORMATION; MOLECULAR CHAPERONES; NMR DIFFUSION; NMR SPECTRUM; NON-FIBRILLAR; THIOFLAVIN T;

DIFFUSION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OLIGOMERIZATION; OLIGOMERS;

MASS SPECTROMETRY;

ALPHA CRYSTALLIN; AMYLOID; BETA 2 MICROGLOBULIN; R3A BETA 2 MICROGLOBULIN; THIOFLAVINE; UNCLASSIFIED DRUG;

ARTICLE; BETA SHEET; CONTROLLED STUDY; COW; DIFFUSION COEFFICIENT; DISSOCIATION; FLUORESCENCE; IN VITRO STUDY; MASS SPECTROMETRY; MONITORING; MUTANT; OLIGOMERIZATION; PH; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PROTEIN INTERACTION; PROTEIN UNFOLDING; PROTON NUCLEAR MAGNETIC RESONANCE; WILD TYPE;

ΑB-CRYSTALLIN; Β2-MICROGLOBULIN; AMYLOID; AMYLOID FIBRILS; MASS SPECTROMETRY (MS); NATIVE MASS SPECTROMETRY; NMR SPECTROSCOPY; NUCLEAR MAGNETIC RESONANCE; PROTEIN AGGREGATION; SMALL HEAT SHOCK PROTEINS;

ALPHA-CRYSTALLIN B CHAIN; AMYLOID; BETA 2-MICROGLOBULIN; FLUORESCENT DYES; HUMANS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN INTERACTION MAPPING; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; THIAZOLES;

EID: 84879039524     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.448639     Document Type: Article

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