α2-Macroglobulin and haptoglobin suppress amyloid formation by interacting with prefibrillar protein species

Journal of Biological Chemistry

Volumn 284, Issue 7, 2009, Pages 4246-4254

  Yerbury, Justin J ^a   Kumita, Janet R ^b   Meehan, Sarah ^b   Dobson, Christopher M ^b   Wilson, Mark R ^a  

^a UNIVERSITY OF WOLLONGONG   (Australia)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMORPHOUS AGGREGATION; AMYLOID FIBRIL; AMYLOID FORMATION; BINDING ACTIVITIES; BIOPHYSICAL TECHNIQUES; EXTRACELLULAR; EXTRACELLULAR ENVIRONMENTS; IN-VITRO; MACROGLOBULIN; PHYSIOLOGICAL CONDITION; PROTEIN SPECIES; SMALL HEAT SHOCK PROTEINS; STRESS-INDUCED;

GLYCOPROTEINS;

PROTEINS;

ALPHA 2 MACROGLOBULIN; AMYLOID; CHAPERONE; GLYCOPROTEIN; HAPTOGLOBIN; HEAT SHOCK PROTEIN; HEMOGLOBIN; PROTEINASE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); PEPTIDE FRAGMENT;

ARTICLE; CONTROLLED STUDY; EXTRACELLULAR SPACE; HUMAN; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN SYNTHESIS; STOICHIOMETRY; CHEMISTRY; DRUG ANTAGONISM; METABOLISM; SOLUBILITY;

ALPHA-MACROGLOBULINS; AMYLOID; AMYLOID BETA-PROTEIN; HAPTOGLOBINS; HEMOGLOBINS; HUMANS; PEPTIDE FRAGMENTS; SOLUBILITY;

EID: 63249134826     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M807242200     Document Type: Article

References (39)

1. Chiti, F., and Dobson, C. M. (2006) Annu. Rev. Biochem. 75, 333-366
2. Jarrett, J. T., and Lansbury, P. T., Jr. (1993) Cell 73, 1055-1058
3. Dobson, C. M. (1999) Trends Biochem. Sci. 24, 329-332
4. Muchowski, P. J., and Wacker, J. L. (2005) Nat. Rev. Neurosci. 6, 11-22
5. Yerbury, J. J., Stewart, E. M., Wyatt, A. R., and Wilson, M. R. (2005) EMBO Rep. 6, 1131-1136
6. Hughes, S. R., Khorkova, O., Goyal, S., Knaeblein, J., Heroux, J., Riedel, N. G., and Sahasrabudhe, S. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 3275-3280
7. Hatters, D. M., Wilson, M. R., Easterbrook-Smith, S. B., and Howlett, G. J. (2002) Eur. J. Biochem. 269, 2789-2794
8. Kumita, J. R., Poon, S., Caddy, G. L., Hagan, C. L., Dumoulin, M., Yerbury, J. J., Stewart, E. M., Robinson, C. V., Wilson, M. R., and Dobson, C. M. (2007) J. Mol. Biol. 369, 157-167
9. Yerbury, J. J., Poon, S., Meehan, S., Thompson, B., Kumita, J. R., Dobson, C. M., and Wilson, M. R. (2007) FASEB J. 21, 2312-2322
10. Yerbury, J. J., Rybchyn, M. S., Easterbrook-Smith, S. B., Henriques, C., and Wilson, M. R. (2005) Biochemistry 44, 10914-10925
11. French, K., Yerbury, J. J., and Wilson, M. R. (2008) Biochemistry 47, 1176-1185
12. Bowman, B. H., and Kurosky, A. (1982) Adv. Hum. Genet. 12, 189-261
13. Sottrup-Jensen, L. (1989) J. Biol. Chem. 264, 11539-11542
14. Imber, M. J., and Pizzo, S. V. (1981) J. Biol. Chem. 256, 8134-8139
15. Narita, M., Holtzman, D. M., Schwartz, A. L., and Bu, G. (1997) J. Neurochem. 69, 1904-1911
16. Adler, V., and Kryukov, V. (2007) Neurochem. J. 1, 43-52
17. Motomiya, Y., Ando, Y., Haraoka, K., Sun, X., Iwamoto, H., Uchimura, T., and Maruyama, I. (2003) Kidney Int. 64, 2244-2252
18. Mettenburg, J. M., Webb, D. J., and Gonias, S. L. (2002) J. Biol. Chem. 277, 13338-13345
19. Barrett, A. J. (1981) Method. Enzymol. 80, 737-754
20. Fabrizi, C., Businaro, R., Lauro, G. M., and Fumagalli, L. (2001) J. Neurochem. 78, 406-412
21. Du, Y., Ni, B., Glinn, M., Dodel, R. C., Bales, K. R., Zhang, Z., Hyslop, P. A., and Paul, S. M. (1997) J. Neurochem. 69, 299-305
22. Dobryszycka, W. (1997) Eur. J. Clin. Chem. Clin. Biochem. 35, 647-654
23. Graversen, J. H., Madsen, M., and Moestrup, S. K. (2002) Int. J. Biochem. Cell Biol. 34, 309-314
24. Louagie, H., Delanghe, J., Desombere, I., De Buyzere, M., Hauser, P., and Leroux-Roels, G. (1993) Vaccine 11, 1188-1190
25. Snellman, O., and Sylven, B. (1967) Nature 216, 1033
26. Pavlicek, Z., and Ettrich, R. (1999) Coll. Czech. Chem. Commun. 64, 717-725
27. Powers, J. M., Schlaepfer, W. W., Willingham, M. C., and Hall, B. J. (1981) J. Neuropathol. Exp. Neurol. 40, 592-612
28. El-Ghmati, S. M., Arredouani, M., Van Hoeyveld, E. M., Ceuppens, J. L., and Stevens, E. A. (2002) Scand. J. Immunol. 55, 352-358
29. Kumita, J. R., Johnson, R. J., Alcocer, M. J., Dumoulin, M., Holmqvist, F., McCammon, M. G., Robinson, C. V., Archer, D. B., and Dobson, C. M. (2006) FEBS J. 273, 711-720
30. Atwood, C. S., Moir, R. D., Huang, X. D., Scarpa, R. C., Bacarra, N. M. E., Romano, D. M., Hartshorn, M. K., Tanzi, R. E., and Bush, A. I. (1998) J. Biol. Chem. 273, 12817-12826
31. Strausak, D., Mercer, J. F., Dieter, H. H., Stremmel, W., and Multhaup, G. (2001) Brain Res. Bull. 55, 175-185
32. Lovell, M., Robertson, J., Teesdale, W., Campbell, J., and Markesbery, W. (1998) J. Neurol. Sci. 158, 47-52
33. Ettrich, R., Brandt, W., Jr., Kopecky, V., Baumruk, V., Hofbauerova, K., and Pavlicek, Z. (2002) Biol. Chem. 383, 1667-1676
34. Starkey, P. M., and Barrett, A. J. (1977) in Proteinases in Mammalian Cells and Tissues (Barrett, A. J., ed) pp. 663-696, Elsevier, Cambridge, MA
35. Humphreys, D. T., Carver, J. A., Easterbrook-Smith, S. B., and Wilson, M. R. (1999) J. Biol. Chem. 274, 6875-6881
36. Shibata, M., Yamada, S., Kumar, S. R., Calero, M., Bading, J., Frangione, B., Holtzman, D. M., Miller, C. A., Strickland, D. K., Ghiso, J., and Zlokovic, B. V. (2000) J. Clin. Investig. 106, 1489-1499
37. Bell, R. D., Sagare, A. P., Friedman, A. E., Bedi, G. S., Holtzman, D. M., Deane, R., and Zlokovic, B. V. (2007) J. Cereb. Blood Flow Metab. 27, 909-918
38. Poon, S., Rybchyn, M. S., Easterbrook-Smith, S. B., Carver, J. A., and Wilson, M. R. (2000) Biochemistry 39, 15953-15960
39. Poon, S., Treweek, T. M., Wilson, M. R., Easterbrook-Smith, S. B., and Carver, J. A. (2002) FEBS Lett. 513, 259-266