1-Phenyl-4-benzoyl-1H-1,2,3-triazoles as orally bioavailable transcriptional function suppressors of Estrogen-related receptor α

Journal of Medicinal Chemistry

Volumn 56, Issue 11, 2013, Pages 4631-4640

  Xu, Shilin ^a,b   Zhuang, Xiaoxi ^a   Pan, Xiaofen ^a   Zhang, Zhang ^a   Duan, Lei ^a   Liu, Yingxue ^a   Zhang, Lianwen ^a   Ren, Xiaomei ^a   Ding, Ke ^a  

^a GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

(2 AMINOPHENYL)(1 (3 ISOPROPYLPHENYL) 1 H 1,2,3 TRIAZOL 4YL)METHANONE; 1,2,3 TRIAZOLE DERIVATIVE; ANTINEOPLASTIC AGENT; ESTROGEN RELATED RECEPTOR ALPHA; MESSENGER RNA; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER INHIBITION; DRUG BIOAVAILABILITY; HUMAN; HUMAN CELL; IC 50; MIGRATION INHIBITION; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; STRUCTURE ACTIVITY RELATION;

ADMINISTRATION, ORAL; ANILINE COMPOUNDS; ANIMALS; ANTINEOPLASTIC AGENTS; BIOLOGICAL AVAILABILITY; BREAST NEOPLASMS; CELL LINE; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; GENES, REPORTER; HUMANS; LUCIFERASES; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ESTROGEN; RNA, MESSENGER; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION, GENETIC; TRIAZOLES;

EID: 84879034381     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm4003928     Document Type: Article

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