Characterization of xylazine metabolism in rat liver microsomes using liquid chromatography-hybrid triple quadrupole-linear ion trap-mass spectrometry

Biomedical Chromatography

Volumn 27, Issue 7, 2013, Pages 882-888

  Lavoie, David St Germain ^a   Pailleux, Floriane ^a,b   Vachon, Pascal ^a   Beaudry, Francis ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b Institut des Sciences Analytiques   (France)

Author keywords

Anesthesia; Bioanalysis; CYP3A; Ketamine; Mass spectrometry; Metabolism; Microsomes; Xylazine

Indexed keywords

AMINES; ANESTHESIOLOGY; BIOMOLECULES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; PHYSIOLOGY; RATS;

ANESTHESIA; BIOANALYSIS; CYP3A; KETAMINE; LIMITED INFORMATION; MICROSOME; QUANTITATIVE METHOD; RAT LIVER MICROSOMES; TRIPLE QUADRUPOLE LINEAR ION TRAP MASS SPECTROMETRIES; XYLAZINE;

METABOLISM;

ACETONITRILE; CLONIDINE; CYTOCHROME P450; FORMIC ACID; METHANOL; WATER; XYLAZINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG HALF LIFE; DRUG METABOLISM; DRUG STABILITY; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; ION TRAP MASS SPECTROMETRY; LIVER MICROSOME; NONHUMAN; PROTEIN ISOLATION; QUANTITATIVE ANALYSIS; RAT; TANDEM MASS SPECTROMETRY;

RATTUS;

EID: 84878999635     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.2875     Document Type: Article

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