Exercise training improve leptin sensitivity in peripheral tissue of obese rats

Biochemical and Biophysical Research Communications

Volumn 435, Issue 3, 2013, Pages 454-459

  Kang, Sunghwun ^a   Kim, Kwi Baek ^b   Shin, Ki Ok ^a  

^a Dong A University   (South Korea)

^b Yongsan University   (South Korea)

Author keywords

Dietary control; Exercise; Hypothalamus; Leptin sensitivity; ObRb; SOCS3

Indexed keywords

LEPTIN; LEPTIN RECEPTOR; MESSENGER RNA; SUPPRESSOR OF CYTOKINE SIGNALING 3; SOCS3 PROTEIN, RAT; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; EXERCISE; HORMONE RESISTANCE; HORMONE SENSITIVITY; HYPOTHALAMUS; LIPID DIET; LIVER; MALE; MUSCLE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; ANIMAL; ANTIBODY SPECIFICITY; CHEMISTRY; GENETICS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; DIET, HIGH-FAT; LEPTIN; MALE; OBESITY; ORGAN SPECIFICITY; PHYSICAL CONDITIONING, ANIMAL; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, LEPTIN; RNA, MESSENGER; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 84878977737     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.05.007     Document Type: Article

References (37)

1. Van Heek M., Compton D.S., France C.F., Tedesco R.P., Fawzi A.B., Graziano M.P., Sybertz E.J., Strader C.D., Davis H.R. Diet-induced obese mice develop peripheral, but not central, resistance to leptin. J. Clin. Invest. 1997, 99:385-390.
2. Schwartz M.W., Peskind E., Raskind M., Boyko E.J., Porte D. Cerebrospinal fluid leptin levels: relationship to plasma levels and to adiposity in humans. Nature Med. 1996, 2:589-593.
3. Banks W.A., Kastin A.J., Huang W., Jaspan J.B., Maness L.M. Leptin enters the brain by a saturable system independent of insulin. Peptides 1996, 17:305-311.
4. Thomas S.A., Preston J.E., Wilson M.R., Farrell C.L., Seqal M.B. Leptin transport at the blood-cerebrospinal fluid barrier using the perfused sheep choroid plexus model. Brain Res. 2001, 895:283-290.
5. Tartaglia L.A., Dembski M., Weng X., Denq N., Culpepper J., Devos R., Richards G.J., Campfield L.A., Clark F.T., Deeds J., Muir C., Sanker S., Moriarty A., Moore K.J., Smutko J.S., Mays G.G., Wool E.A., Monroe C.A., Tepper R.I. Identification and expression cloning of a leptin receptor. OB-R Cell 1995, 83:1263-1271.
6. Friedman J.M. Leptin at 14 y of age: an ongoing story. Am. J. Clin. Nutr. 2009, 89:973S-979S.
7. Ahima R.S., Saper C.B., Flier J.S., Elmquist J.K. Leptin regulation of neuroendocrine system. Front. Neuroendocrinol. 2000, 21:263-307.
8. Myers M.G., Münzberg H., Leinninger G.M., Leshan R.L. The geometry of leptin action in the brain: more complicated than a simple ARC. Cell Metab. 2009, 9:117-123.
9. Rosenbaum M., Leibel R.L. The role of leptin in human physiology. N. Engl. J. Med. 1999, 341:913-915.
10. Schwartz M.W., Woods S.C., Porte D., Seeley R.J., Baskin D.G. Central nervous system control of food intake. Nature 2000, 404:661-671.
11. Ogimoto K., Harris M.K., Wisse B.E. MyD88 is a key mediator of anorexia, but not weight loss, induced by lipopolysaccharide and interleukin-1 beta. Endocrinology 2006, 147:4445-4453.
12. Ozcan L., Ergin A.S., Lu A., Chung J., Sarkar S., Nie D., Myers M.G., Ozcan U. Endoplasmic reticulum stress plays a central role in development of leptin resistance. Cell Metab. 2009, 9:35-51.
13. Zhang X., Zhang G., Zhang H., Karin M., Bai H., Cai D. Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity. Cell 2008, 135:61-73.
14. Misra A., Alappan N.K., Vikram N.K., Goel K., Gupta N., Mittal K., Bhatt S., Luthra K. Effect of supervised progressive resistance-exercise training protocol on insulin sensitivity, glycemia, lipids, and body composition in Asian Indians with type 2 diabetes. Diabetes Care 2008, 31:1282-1287.
15. Tuomilehto J., Lindström J., Eriksson J.G., Valle T.T., Hämäläinen H., Ilanne-Parikka P., Keinänen-Kiukaanniemi S., Laakso M., Louheranta A., Rastas M., Salminen V., Uusitupa M. Finnish diabetes prevention study group, prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N. Engl. J. Med. 2001, 344:1343-1350.
16. Woo J., Yeo N.H., Shin K.O., Lee H.J., Yoo J., Kang S. Antioxidant enzyme activities and DNA damage in children with type 1 diabetes mellitus after 12weeks of exercise. Acta Paediatr. 2010, 99:1263-1268.
17. Harriss D.J., Atkinson G. International journal of sports medicine-ethical standards in sport and exercise science research. Int. J. Sports Med. 2009, 30:701-702.
18. Institute for Laboratory Animal Research, National Research Council, Guide for the Care and Use of Laboratory Animals, National Academy Press, Washington, DC, 1996, p. 140.
19. Coppari R., Ramadori G., Elmquist J.K. The role of transcriptional regulators in central control of appetite and body weight. Nat. Clin. Pract. Endocrinol. Metab. 2009, 5:160-166.
20. Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., Friedman J.M. Positional cloning of the mouse obese gene and its human homologue. Nature 1994, 372:425-432.
21. Scarpace P.J., Zhang Y. Leptin resistance: A predisposing factor for diet-induced obesity. Am. J. Physiol. Integr. Comp. Physiol. 2009, 296:R493-R500.
22. Maffei M., Fei H., Lee G.H., Dani C., Leroy P., Zhang Y., Proenca R., Negrel R., Ailhaud G., Friedman J.M. Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus. Proc. Natl. Acad. Sci. USA 1995, 92:6957-6960.
23. C.M. Patterson, S.G. Bouret, A.A. Dunn-Meynell, B.E. Levin, Three weeks of postweaning exercise in DIO rats produces prolonged increases in central leptin sensitivity and signaling, Am. J. Physiol. Regul. Integr. Physiol. 296 (296) R537-R548.
24. Vieira V.J., Valentine R.J., Wilund K.R., Antao N., Baynard T., Woods J.A. Effects of exercise and low-fat diet on adipose tissue inflammation and metabolic complications in obese mice. Am. J. Physiol. Endocrinol. Metab. 2009, 296:E1164-E1171.
25. Weiss E.P., Racette S.B., Villareal D.T., Fontana L., Steger-May K., Schechtman K.B., Klein S., Holloszy J.O. Washington University School of Medicine CALERIE Group, improvements in glucose tolerance and insulin action induced by increasing energy expenditure or decreasing energy intake: a randomized controlled trial. Am. J. Clin. Nutr. 2006, 84:1033-1042.
26. Zarins Z.A., Johnson M.L., Faghihnia N., Horning M.A., Wallis G.A., Fattor J.A., Brooks G.A. Training improves the response in glucose flux to exercise in postmenopausal women. J. Appl. Physiol. 2009, 107:90-97.
27. rdResistance training enhances componets of the insulin signaling cascade in normal and high-fat-fed rodent skeletal muscle. J. Appl. Physiol. 2004, 96:1691-1700.
28. Baumann H., Morella K.K., White D.W., Dembski M., Bailon P.S., Kim H., Lai C.F., Tartaglia L.A. The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors. Proc. Natl. Acad. Sci. USA 1996, 93:8374-8378.
29. Bjørbaek C., El-Haschimi K., Frantz J.D., Flier J.S. The role of SOCS-3 in leptin signaling and leptin resistance. J. Biol. Chem. 1999, 274:30059-30065.
30. Flores M.B., Fernandes M.F., Ropelle E.R., Faria M.C., Ueno M., Velloso L.A., Saad M.J., Carvalheira J.B. Exercise improves insulin and leptin sensitivity in hypothalamus of Wistar rats. Diabetes 2006, 55:2554-2561.
31. Niimi M., Sato M., Yokote R., Tada S., Takahara J. Effects of central of peripheral injection of leptin on food intake and on brain Fos expression in the Otsuka Long-Evans Tokushima Fatty rat with hyperleptinaemia. J. Neuroendocrinol. 1999, 11:605-611.
32. Han Y., Joe Y., Seo E., Lee S.R., Park M.K., Lee H.J., Kim D.K. The hyperleptinemia and ObRb expression in hyperphagic obese rats. Biochem. Biophys. Res. Commun. 2010, 394:70-74.
33. Moran T.H., McHugh P.R. Cholecystokinin suppresses food intake by inhibiting gastric emptying. Am. J. Physiol. 1982, 242:R491-R497.
34. Shimokawa I., Higami Y. Leptin and anti-aging action of caloric restriction. Nutr. Health Aging 2001, 5:43-48.
35. Mainardi M., Scabia G., Vottari T., Santini F., Pinchera A., Maffei L., Pizzorusso T., Maffei M. A sensitive period for environmental regulation of eating behavior and leptin sensitivity. Proc. Natl. Acad. Sci. USA 2010, 107:16673-16678.
36. Bruce C.R., Lee J.S., Kiens B., Hawley J.A. Postexercise muscle triacylglycerol and glycogen metabolism in obese insulin-resistant zucker rats. Obes. Res. 2004, 12:1158-1165.
37. Shapiro A., Matheny M., Zhang Y., Tumer N., Cheng K.Y., Rogrigues E., Zolotukhin S., Scarpace P.J. Synergy between leptin therapy and a seemingly negligible amout of voluntary wheel running prevents of dietary obesity in leptin-resistant rats. Diabetes 2008, 57:614-622.