Anti-inflammatory effects of essential oils from Chamaecyparis obtusa via the cyclooxygenase-2 pathway in rats

Molecular Medicine Reports

Volumn 8, Issue 1, 2013, Pages 255-259

  An, Beum Soo ^a,b   Kang, Ji Houn ^a   Yang, Hyun ^a   Jung, Eui Man ^a   Kang, Hong Seok ^a   Choi, In Gyu ^c   Park, Mi Jin ^d   Jeung, Eui Bae ^a  

^a Chungbuk National University   (South Korea)

^b Pusan National University   (South Korea)

^c Seoul National University   (South Korea)

^d Korea Forest Research Institute   (South Korea)

Author keywords

Anti inflammation; Chamaecyparis obtusa; COX 2; Essential oil; PGE2; TNF

Indexed keywords

ANTIINFLAMMATORY AGENT; CHAMAECYPARIS OBTUSA EXTRACT; CYCLOOXYGENASE 2; ESSENTIAL OIL; MESSENGER RNA; PLANT EXTRACT; PROSTAGLANDIN E2; TERPENE DERIVATIVE; TRANSFORMING GROWTH FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL VIABILITY; CHAMAECYPARIS; CHAMAECYPARIS OBTUSA; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CHAMAECYPARIS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DINOPROSTONE; INFLAMMATION; LIPOPOLYSACCHARIDES; LUNG; MALE; OILS, VOLATILE; RATS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

CHAMAECYPARIS OBTUSA; RATTUS;

EID: 84878952227     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1459     Document Type: Article

References (27)

1. Simmons DL, Botting RM and Hla T: Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition. Pharmacol Rev 56: 387-437, 2004. (Pubitemid 39096597)
2. Smith WL: Nutritionally essential fatty acids and biologically indispensable cyclooxygenases. Trends Biochem Sci 33: 27-37, 2008.
3. Koki A, Khan NK, Woerner BM, et al: Cyclooxygenase-2 in human pathological disease. Adv Exp Med Biol 507: 177-184, 2002. (Pubitemid 37330179)
4. Zha S, Yegnasubramanian V, Nelson WG, Isaacs WB and De Marzo AM: Cyclooxygenases in cancer: progress and perspective. Cancer Lett 215: 1-20, 2004. (Pubitemid 39221453)
5. Cuzick J, Otto F, Baron JA, et al: Aspirin and non-steroidal anti-inflammatory drugs for cancer prevention: an international consensus statement. Lancet Oncol 10: 501-507, 2009.
6. Thun MJ and Blackard B: Pharmacologic effects of NSAIDs and implications for the risks and benefits of long-term prophylactic use of aspirin to prevent cancer. Recent Results Cancer Res 181: 215-221, 2009.
7. Mukherjee D: Selective cyclooxygenase-2 (COX-2) inhibitors and potential risk of cardiovascular events. Biochem Pharmacol 63: 817-821, 2002.
8. Coruzzi G, Venturi N and Spaggiari S: Gastrointestinal safety of novel nonsteroidal antiinflammatory drugs: selective COX-2 inhibitors and beyond. Acta Biomed 78: 96-110, 2007.
9. Li W, Zhou P, Zhang Y and He L: Houttuynia cordata, a novel and selective COX-2 inhibitor with anti-inflammatory activity. J Ethnopharmacol 133: 922-927, 2011.
10. Joo SS, Yoo YM, Ko SH, et al: Effects of essential oil from Chamaecypris obtusa on the development of atopic dermatitis-like skin lesions and the suppression of Th cytokines. J Dermatol Sci 60: 122-125, 2010.
11. Singh BK, Tripathi M, Chaudhari BP, Pandey PK and Kakkar P: Natural terpenes prevent mitochondrial dysfunction, oxidative stress and release of apoptotic proteins during nimesulide-hepatotoxicity in rats. PLoS One 7: e34200, 2012.
12. Lee GS, Byun HS, Kim MH, et al: The beneficial effect of the sap of Acer mono in an animal with low-calcium diet-induced osteoporosis-like symptoms. Br J Nutr 100: 1011-1018, 2008.
13. Lee GS, Hong EJ, Gwak KS, et al: The essential oils of Chamaecyparis obtusa promote hair growth through the induction of vascular endothelial growth factor gene. Fitoterapia 81: 17-24, 2010.
14. Lee SC, Ju SA, Pack HN, et al: 4-1BB (CD137) is required for rapid clearance of Listeria monocytogenes infection. Infect Immun 73: 5144-5151, 2005.
15. Hasegawa H, Suzuki K, Nakaji S and Sugawara K: Analysis and assessment of the capacity of neutrophils to produce reactive oxygen species in a 96-well microplate format using lucigenin- and luminol-dependent chemiluminescence. J Immunol Methods 210: 1-10, 1997. (Pubitemid 127445147)
16. Vo TT, An BS, Yang H, Jung EM, Hwang I and Jeung EB: Calbindin-D9k as a sensitive molecular biomarker for evaluating the synergistic impact of estrogenic chemicals on GH3 rat pituitary cells. Int J Mol Med 30: 1233-1240, 2012.
17. Takayama C, de-Faria FM, de Almeida AC, et al: Gastroprotective and ulcer healing effects of essential oil from Hyptis spicigera Lam. (Lamiaceae). J Ethnopharmacol 135: 147-155, 2011.
18. Edris AE: Pharmaceutical and therapeutic potentials of essential oils and their individual volatile constituents: a review. Phytother Res 21: 308-323, 2007.
19. Silva FV, Guimarães AG, Silva ER, et al: Anti-inflammatory and anti-ulcer activities of carvacrol, a monoterpene present in the essential oil of oregano. J Med Food 15: 984-991, 2012.
20. Lima DK, Ballico LJ, Rocha Lapa F, et al: Evaluation of the antinociceptive, anti-inflammatory and gastric antiulcer activities of the essential oil from Piper aleyreanum C.DC in rodents. J Ethnopharmacol 142: 274-282, 2012.
21. Veras HN, Araruna MK, Costa JG, et al: Topical antiinflammatory activity of essential oil of Lippia sidoides Cham: possible mechanism of action. Phytother Res 27: 179-185, 2012.
22. Hennebert O, Pelissier MA, Le Mee S, Wülfert E and Morfin R: Anti-inflammatory effects and changes in prostaglandin patterns induced by 7beta-hydroxy-epiandrosterone in rats with colitis. J Steroid Biochem Mol Biol 110: 255-262, 2008.
23. Raymundo LJ, Guilhon CC, Alviano DS, et al: Characterisation of the anti-inflammatory and antinociceptive activities of the Hyptis pectinata (L.) Poit essential oil. J Ethnopharmacol 134: 725-732, 2011.
24. Yoon WJ, Kim SS, Oh TH, Lee NH and Hyun CG: Cryptomeria japonica essential oil inhibits the growth of drug-resistant skin pathogens and LPS-induced nitric oxide and pro-inflammatory cytokine production. Pol J Microbiol 58: 61-68, 2009.
25. Chao LK, Hua KF, Hsu HY, et al: Cinnamaldehyde inhibits pro-inflammatory cytokines secretion from monocytes/macrophages through suppression of intracellular signaling. Food Chem Toxicol 46: 220-231, 2008. (Pubitemid 350235768)
26. Takeda K, Kaisho T and Akira S: Toll-like receptors. Annu Rev Immunol 21: 335-376, 2003. (Pubitemid 37174535)
27. Katsukawa M, Nakata R, Takizawa Y, Hori K, Takahashi S and Inoue H: Citral, a component of lemongrass oil, activates PPARalpha and gamma and suppresses COX-2 expression. Biochim Biophys Acta 1801: 1214-1220, 2010.