-
1
-
-
23744431849
-
Chemotherapy in metastatic renal cell cancer
-
DOI 10.1007/s00345-004-0469-x
-
LillebyW, Fossa SD. Chemotherapy in metastatic renal cell cancer. World J Urol 2005; 23:175-179. (Pubitemid 41136038)
-
(2005)
World Journal of Urology
, vol.23
, Issue.3
, pp. 175-179
-
-
Lilleby, W.1
Fossa, S.D.2
-
2
-
-
0042821661
-
Chemotherapeutic strategies for renal cell carcinoma
-
DOI 10.1016/S0094-0143(03)00031-4
-
Milowsky MI, Nanus DM. Chemotherapeutic strategies for renal cell carcinoma. Urol Clin North Am 2003; 30:601-609. (Pubitemid 37059565)
-
(2003)
Urologic Clinics of North America
, vol.30
, Issue.3
, pp. 601-609
-
-
Milowsky, M.I.1
Nanus, D.M.2
-
3
-
-
0028929682
-
Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy
-
Fyfe G, Fisher RI, Rosenberg SA, Sznol M, Parkinson DR, Louie AC. Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy. J Clin Oncol 1995; 13:688-696.
-
(1995)
J Clin Oncol
, vol.13
, pp. 688-696
-
-
Fyfe, G.1
Fisher, R.I.2
Rosenberg, S.A.3
Sznol, M.4
Parkinson, D.R.5
Louie, A.C.6
-
4
-
-
0033514050
-
Interferon-alpha and survival in metastatic renal carcinoma: Early results of a randomized controlled trial
-
Medical Research Council Renal Cancer Collaborators
-
Medical Research Council Renal Cancer Collaborators. Interferon-alpha and survival in metastatic renal carcinoma: early results of a randomized controlled trial. Lancet 1999; 353:14-17.
-
(1999)
Lancet
, vol.353
, pp. 14-17
-
-
-
5
-
-
56749161699
-
Bevacizumab plus interferon alfa compared with interferon alfa monotherapy in patients with metastatic renal cell carcinoma: CALGB 90206
-
Rini BI, Halabi S, Rosenberg JE, Stadler WM, Vaena DA, Ou SS, et al. Bevacizumab plus interferon alfa compared with interferon alfa monotherapy in patients with metastatic renal cell carcinoma: CALGB 90206. J Clin Oncol 2008; 26:5422-5428.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5422-5428
-
-
Rini, B.I.1
Halabi, S.2
Rosenberg, J.E.3
Stadler, W.M.4
Vaena, D.A.5
Ou, S.S.6
-
6
-
-
77952318310
-
Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: Final results of CALGB 90206
-
Rini BI, Halabi S, Rosenberg JE, Stadler WM, Vaena DA, Archer L, et al. Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: final results of CALGB 90206. J Clin Oncol 2010; 28:2137-2143.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2137-2143
-
-
Rini, B.I.1
Halabi, S.2
Rosenberg, J.E.3
Stadler, W.M.4
Vaena, D.A.5
Archer, L.6
-
7
-
-
37349080670
-
Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: A randomised, double-blind phase III trial
-
DOI 10.1016/S0140-6736(07)61904-7, PII S0140673607619047
-
Escudier B, Pluzanska A, Koralewski P, Ravaud A, Bracarda S, Szczylik C, et al. AVOREN Trial investigators. Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial. Lancet 2007; 370:2103-2111. (Pubitemid 350296300)
-
(2007)
Lancet
, vol.370
, Issue.9605
, pp. 2103-2111
-
-
Escudier, B.1
Pluzanska, A.2
Koralewski, P.3
Ravaud, A.4
Bracarda, S.5
Szczylik, C.6
Chevreau, C.7
Filipek, M.8
Melichar, B.9
Bajetta, E.10
Gorbunova, V.11
Bay, J.-O.12
Bodrogi, I.13
Jagiello-Gruszfeld, A.14
Moore, N.15
-
8
-
-
77952300540
-
Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): Final analysis of overall survival
-
Escudier B, Bellmunt J, Negrier S, Bajetta E, Melichar B, Bracarda S, et al. Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): final analysis of overall survival. J Clin Oncol 2010; 28:2144-2150.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2144-2150
-
-
Escudier, B.1
Bellmunt, J.2
Negrier, S.3
Bajetta, E.4
Melichar, B.5
Bracarda, S.6
-
9
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
DOI 10.1056/NEJMoa065044
-
Motzer RJ, Hutson T, Tomczak P, Michaelson MD, Bukowski RM, Rixe O, et al. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 2007; 356:115-124. (Pubitemid 46089672)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.2
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
Michaelson, D.4
Bukowski, R.M.5
Rixe, O.6
Oudard, S.7
Negrier, S.8
Szczylik, C.9
Kim, S.T.10
Chen, I.11
Bycott, P.W.12
Baum, C.M.13
Figlin, R.A.14
-
10
-
-
68949145218
-
Overall survival and updated results for sunitinb compared with interferon alfa in patients with metastatic renal cell carcinoma
-
Motzer RJ, Hutson T, Tomczak P, Michaelson MD, Bukowski RM, Oudard S, et al. Overall survival and updated results for sunitinb compared with interferon alfa in patients with metastatic renal cell carcinoma. J Clin Oncol 2009; 27:3584-3590.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3584-3590
-
-
Motzer, R.J.1
Hutson, T.2
Tomczak, P.3
Michaelson, M.D.4
Bukowski, R.M.5
Oudard, S.6
-
11
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
DOI 10.1056/NEJMoa060655
-
Escudier B, Eisen T, Stadler WM, Szczylik C, Oudard S, Siebels M, et al. TARGET Study Group. Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med 2007; 356:125-134. (Pubitemid 46089673)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.2
, pp. 125-134
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
Szczylik, C.4
Oudard, S.5
Siebels, M.6
Negrier, S.7
Chevreau, C.8
Solska, E.9
Desai, A.A.10
Rolland, F.11
Demkow, T.12
Hutson, T.E.13
Gore, M.14
Freeman, S.15
Schwartz, B.16
Shan, M.17
Simantov, R.18
Bukowski, R.M.19
-
12
-
-
70249097380
-
Sorafenib for treatment of renal cell carcinoma: Final efficacy and safety results of the phase III treatment approaches in renal cancer global evaluation trial
-
Escudier B, Eisen T, Stadler WM, Szczylik C, Oudard S, Staehler M, et al. Sorafenib for treatment of renal cell carcinoma: final efficacy and safety results of the phase III treatment approaches in renal cancer global evaluation trial. J Clin Oncol 2009; 27:3312-3318.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3312-3318
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
Szczylik, C.4
Oudard, S.5
Staehler, M.6
-
13
-
-
77949890945
-
Pazopanib in locally advanced or metastatic renal cell carcinoma: Results of a randomized phase III trial
-
Sternberg CN, Davis ID, Mardiak J, Szczylik C, Lee E, Wagstaff J, et al. Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial. J Clin Oncol 2010; 28:1061-1068.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1061-1068
-
-
Sternberg, C.N.1
Davis, I.D.2
Mardiak, J.3
Szczylik, C.4
Lee, E.5
Wagstaff, J.6
-
14
-
-
77956227464
-
Phase 3 trial of everolimus for metastatic renal cell carcinoma: Final results and analysis of prognostic factors
-
RECORD-1 Study Group
-
Motzer RJ, Escudier B, Oudard S, Hutson TE, Porta C, Bracarda S, et al. RECORD-1 Study Group. Phase 3 trial of everolimus for metastatic renal cell carcinoma: final results and analysis of prognostic factors. Cancer 2010;4256-4265.
-
(2010)
Cancer
, pp. 4256-4265
-
-
Motzer, R.J.1
Escudier, B.2
Oudard, S.3
Hutson, T.E.4
Porta, C.5
Bracarda, S.6
-
15
-
-
34249779568
-
Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
-
DOI 10.1056/NEJMoa066838
-
Hudes G, Carducci M, Tomczak P, Dutcher J, Figlin R, Kapoor A, et al. Global ARCC Trial. Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. N Engl J Med 2007; 356:2271-2281. (Pubitemid 46849157)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.22
, pp. 2271-2281
-
-
Hudes, G.1
Carducci, M.2
Tomczak, P.3
Dutcher, J.4
Figlin, R.5
Kapoor, A.6
Staroslawska, E.7
Sosman, J.8
McDermott, D.9
Bodrogi, I.10
Kovacevic, Z.11
Lesovoy, V.12
Schmidt-Wolf, I.G.H.13
Barbarash, O.14
Gokmen, E.15
O'Toole, T.16
Lustgarten, S.17
Moore, L.18
Motzer, R.J.19
-
16
-
-
73349084973
-
Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted agents: Results from a large, multicenter study
-
Heng DY, Xie W, Regan MM, Warren MA, Golshayan AR, Sahi C, et al. Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted agents: results from a large, multicenter study. J Clin Oncol 2009; 27:5794-5799.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5794-5799
-
-
Heng, D.Y.1
Xie, W.2
Regan, M.M.3
Warren, M.A.4
Golshayan, A.R.5
Sahi, C.6
-
17
-
-
47949099628
-
Modes of resistance to anti-angiogenic therapy
-
Bergers G, Hanahan D. Modes of resistance to anti-angiogenic therapy. Nat Rev Cancer 2008; 8:592-603.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 592-603
-
-
Bergers, G.1
Hanahan, D.2
-
19
-
-
12144289948
-
Capecitabine monotherapy and in combination with immunotherapy in the treatment of metastatic renal cell carcinoma
-
Wenzel C, Locker GJ, Bartsch R, Pluschnig U, Mader R, Hussian D, et al. Capecitabine monotherapy and in combination with immunotherapy in the treatment of metastatic renal cell carcinoma. Anticancer Drugs 2003; 14:779-784. (Pubitemid 38339781)
-
(2003)
Anti-Cancer Drugs
, vol.14
, Issue.10
, pp. 779-784
-
-
Wenzel, C.1
Locker, G.J.2
Bartsch, R.3
Pluschnig, U.4
Mader, R.5
Hussian, D.6
Kramer, G.7
Marberger, M.8
Lintner, C.9
Rauchenwald, M.10
Zielinski, C.C.11
Steger, G.G.12
-
20
-
-
34250874424
-
Capecitabine as third-line treatment in patients with metastatic renal cell carcinoma after failing immunotherapy
-
DOI 10.1097/CAD.0b013e3280a02f17, PII 0000181320070800000009
-
Petrioli R, Paolelli L, Francini E, Marsili S, Pascucci A, Sciandivasci A, et al. Capecitabine as third-line treatment in patients with metastatic renal cell carcinoma after failing immunotherapy. Anticancer Drugs 2007; 18: 817-820. (Pubitemid 46975968)
-
(2007)
Anti-Cancer Drugs
, vol.18
, Issue.7
, pp. 817-820
-
-
Petrioli, R.1
Paolelli, L.2
Francini, E.3
Marsili, S.4
Pascucci, A.5
Sciandivasci, A.6
De Rubertis, G.7
Barbanti, G.8
Manganelli, A.9
Salvestrini, F.10
Francini, G.11
-
21
-
-
84861530844
-
Phase II, multicenter, uncontrolled trial of singleagent capecitabine in patients with non-clear cell metastatic renal cell carcinoma
-
Tsimafeyeu I, Demidov L, Kharkevich G, Petenko N, Galchenko V, Sinelnikov I, Naidzionak U. Phase II, multicenter, uncontrolled trial of singleagent capecitabine in patients with non-clear cell metastatic renal cell carcinoma. Am J Clin Oncol 2012; 35:251-254.
-
(2012)
Am J Clin Oncol
, vol.35
, pp. 251-254
-
-
Tsimafeyeu, I.1
Demidov, L.2
Kharkevich, G.3
Petenko, N.4
Galchenko, V.5
Sinelnikov, I.6
Naidzionak, U.7
-
22
-
-
79951888205
-
Multicenter phase II trial of S-1 in patients with cytokine-refractory metastatic renal cell carcinoma
-
Naito S, Eto M, Shinohara N, Tomita Y, Fujisawa M, Namiki M, et al. Multicenter phase II trial of S-1 in patients with cytokine-refractory metastatic renal cell carcinoma. J Clin Oncol 2010; 28: 5022-5029.
-
(2010)
J Clin Oncol
, vol.28
, pp. 5022-5029
-
-
Naito, S.1
Eto, M.2
Shinohara, N.3
Tomita, Y.4
Fujisawa, M.5
Namiki, M.6
-
23
-
-
0037687354
-
Phase II study of troxacitabine (BCH-4556) in patients with advanced and/or metastatic renal cell carcinoma: A trial of the National Cancer Institute of Canada-Clinical Trials Group
-
DOI 10.1200/JCO.2003.03.057
-
Townsley CA, Chi K, Ernst SD, Belanger K, Tannock I, Bjarnason GA, et al. National Cancer Institute of Canada-Clinical Trials Group. Phase II study of troxacitabine (BHC-4556) in patients with advanced and/or metastatic renal cell carcinoma: a trial of the National Cancer Institute of Canada- Clinical Trials Group. J Clin Oncol 2003; 21:1524-1529. (Pubitemid 46594105)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.8
, pp. 1524-1529
-
-
Townsley, C.A.1
Chi, K.2
Ernst, D.S.3
Belanger, K.4
Tannock, I.5
Bjarnason, G.A.6
Stewart, D.7
Goel, R.8
Ruether, J.D.9
Siu, L.L.10
Jolivet, J.11
McIntosh, L.12
Seymour, L.13
Moore, M.J.14
-
24
-
-
1642575350
-
A phase II study of rebeccamycin analog (NSC-655649) in metastatic renal cell cancer
-
DOI 10.1023/A:1026259503954
-
Hussain M, Vaishampayan U, Heilbrun LK, Jain V, LoRusso PM, Ivy P, Flaherty L. A phase II study of rebeccamycin analog (NSC-655649) in metastatic renal cell cancer. Invest New Drugs 2003; 21:465-471. (Pubitemid 38124987)
-
(2003)
Investigational New Drugs
, vol.21
, Issue.4
, pp. 465-471
-
-
Hussain, M.1
Vaishampayan, U.2
Heilbrun, L.K.3
Jain, V.4
LoRusso, P.M.5
Ivy, P.6
Flaherty, L.7
-
25
-
-
0344851699
-
A phase II trial of pemetrexed in patients with metastatic renal cancer
-
DOI 10.1023/A:1025480914273
-
Thödtmann R, Sauter T, Weinknecht S, Weissbach L, Blatter J, Ohnmacht U, Hanauske A. A phase II trial of pemetrexed in patients with metastatic renal cancer. Invest New Drugs 2003; 21:353-358. (Pubitemid 37486336)
-
(2003)
Investigational New Drugs
, vol.21
, Issue.3
, pp. 353-358
-
-
Thodtmann, R.1
Sauter, T.2
Weinknecht, S.3
Weissbach, L.4
Blatter, J.5
Ohnmacht, U.6
Hanauske, A.-R.7
-
26
-
-
0037665007
-
A phase II study of irinotecan in patients with advanced renal cell carcinoma
-
DOI 10.1002/cncr.11474
-
Fizazi K, Rolland F, Chevreau C, Droz JP, Mery-Mignard D, Culine S, Escudier B. A phase II study of irinotecan in patients with advanced renal cell carcinoma. Cancer 2003; 98:61-65. (Pubitemid 36741126)
-
(2003)
Cancer
, vol.98
, Issue.1
, pp. 61-65
-
-
Fizazi, K.1
Rolland, F.2
Chevreau, C.3
Droz, J.-P.4
Mery-Mignard, D.5
Culine, S.6
Escudier, B.7
-
27
-
-
33745042184
-
Phase II study of vinflunine in patients with metastatic renal cell carcinoma
-
DOI 10.1007/s10637-006-6437-0
-
Goldstein D, Ackland SP, Bell DR, Olver IN, Davis ID, Rosenthal MA, et al. Phase II study of vinflunine in patients with metastatic renal cell carcinoma. Invest New Drugs 2006; 24:429-434. (Pubitemid 43876079)
-
(2006)
Investigational New Drugs
, vol.24
, Issue.5
, pp. 429-434
-
-
Goldstein, D.1
Ackland, S.P.2
Bell, D.R.3
Olver, I.N.4
Davis, I.D.5
Rosenthal, M.A.6
Toner, G.C.7
Pinel, M.C.8
Byrne, M.9
-
28
-
-
77649106272
-
A phase II clinical trial of ixabepilone (Ixempra; BMS-247550; NSC 710428), an epothilone B analog, in patients with metastatic renal cell carcinoma
-
Huang H, Menefee M, Edgerly M, Zhuang S, Kotz H, Poruchynsky M, et al. A phase II clinical trial of ixabepilone (Ixempra; BMS-247550; NSC 710428), an epothilone B analog, in patients with metastatic renal cell carcinoma. Clin Cancer Res 2010; 16:1634-1641.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1634-1641
-
-
Huang, H.1
Menefee, M.2
Edgerly, M.3
Zhuang, S.4
Kotz, H.5
Poruchynsky, M.6
-
29
-
-
0038793710
-
IPM chemotherapy in cytokine refractory renal cell cancer
-
DOI 10.1038/sj.bjc.6600934
-
Shamash J, Steele JP, Wilson P, Nystrom M, Ansell W, Oliver RT. IMP chemotherapy in cytokine refractory renal cell cancer. Br J Cancer 2003; 88:1516-1521. (Pubitemid 36713775)
-
(2003)
British Journal of Cancer
, vol.88
, Issue.10
, pp. 1516-1521
-
-
Shamash, J.1
Steele, J.P.2
Wilson, P.3
Nystrom, M.4
Ansell, W.5
Oliver, R.T.D.6
-
30
-
-
0037215201
-
A phase II study with 5-fluorouracil, folinic acid and oxaliplatin (FOLFOX-4 regimen) in patients with metastatic renal cell carcinoma
-
DOI 10.1159/000066518
-
Bennouna J, Delva R, Gomez F, Lesimple T, Geoffrois L, Linassier C, et al. A phase II study with 5-fluorouracil, folinic acid and oxaliplatin (FOLFOX-4 regimen) in patients with metastatic renal cell carcinoma. Oncology 2003; 64:25-27. (Pubitemid 35477951)
-
(2003)
Oncology
, vol.64
, Issue.1
, pp. 25-27
-
-
Bennouna, J.1
Delva, R.2
Gomez, F.3
Lesimple, T.4
Geoffrois, L.5
Linassier, C.6
Chevreau, C.7
Douillard, J.Y.8
Negrier, S.9
-
31
-
-
2342452468
-
Gemcitabine and Oxaliplatin in the Treatment of Patients with Immunotherapy-Resistant Advanced Renal Cell Carcinoma: Final Results of a Single-Institution Phase II Study
-
DOI 10.1002/cncr.20226
-
Porta C, Zimatore M, Imarisio I, Natalizi A, Sartore-Bianchi A, Danova M, Riccardi A. Gemcitabine and oxaliplatin in the treatment of patients with immunotherapy-resistant advanced renal cell carcinoma. Cancer 2004; 100:2132-2138. (Pubitemid 38580331)
-
(2004)
Cancer
, vol.100
, Issue.10
, pp. 2132-2138
-
-
Porta, C.1
Zimatore, M.2
Imarisio, I.3
Natalizi, A.4
Sartore-Bianchi, A.5
Danova, M.6
Riccardi, A.7
-
32
-
-
0142150101
-
Vinblastine and estramustine phosphate in metastatic renal cell carcinoma
-
Haas NB, Giantonio BJ, Litwin S, Minniti CJ Jr, Fox S, Yeslow G, et al. Vinblastine and estramustine phosphate in metastatic renal cell carcinoma. Cancer 2003; 98:1837-1841.
-
(2003)
Cancer
, vol.98
, pp. 1837-1841
-
-
Haas, N.B.1
Giantonio, B.J.2
Litwin, S.3
Minniti Jr., C.J.4
Fox, S.5
Yeslow, G.6
-
33
-
-
0041691157
-
Prognostic factors for survival with gemcitabine plus 5-fluorouracil based regimens for metastatic renal cancer
-
DOI 10.1097/01.ju.0000086829.74971.4a
-
Stadler WM, Huo D, George C, Yang X, Ryan CW, Karrison T, et al. Prognostic factors for survival with gemcitabine plus 5-fluorouracil based regimens for metastatic renal cancer. J Urol 2003; 170: 1141-1145. (Pubitemid 37108098)
-
(2003)
Journal of Urology
, vol.170
, Issue.4
, pp. 1141-1145
-
-
Stadler, W.M.1
Huo, D.2
George, C.3
Yang, X.4
Ryan, C.W.5
Karrison, T.6
Zimmerman, T.M.7
Vogelzang, N.J.8
-
34
-
-
10644239649
-
Phase II clinical trial of capecitabine and gemcitabine chemotherapy in patients with metastatic renal carcinoma
-
DOI 10.1038/sj.bjc.6602209
-
Waters JS, Moss C, Pyle L, James M, Hackett S, A'hern R, et al. Phase II clinical trial of capecitabine and gemcitabine in patients with metastatic renal carcinoma. Br J Cancer 2004; 91:1763-1768. (Pubitemid 39664962)
-
(2004)
British Journal of Cancer
, vol.91
, Issue.10
, pp. 1763-1768
-
-
Waters, J.S.1
Moss, C.2
Pyle, L.3
James, M.4
Hackett, S.5
A'Hern, R.6
Gore, M.7
Eisen, T.8
-
35
-
-
33749032810
-
A phase II study of gemcitabine and capecitabine in metastatic renal cancer
-
Cancer and Leukemia Group B
-
Stadler WM, Halabi S, Rini B, Ernstoff MS, Davila E, Picus J, et al. Cancer and Leukemia Group B. A phase II study of gemcitabine and capecitabine in metastatic renal cancer. Cancer 2006; 107:1273-1279.
-
(2006)
Cancer
, vol.107
, pp. 1273-1279
-
-
Stadler, W.M.1
Halabi, S.2
Rini, B.3
Ernstoff, M.S.4
Davila, E.5
Picus, J.6
-
36
-
-
48649102073
-
Capecitabine for metastatic renal cell cancer previously treated with immunotherapy and targeted agents
-
Tannir NM, Thall PF, Ng CS, Wang X, Wooten L, Siefker-Radtke A, et al. Capecitabine for metastatic renal cell cancer previously treated with immunotherapy and targeted agents. J Urol 2008; 180:867-872.
-
(2008)
J Urol
, vol.180
, pp. 867-872
-
-
Tannir, N.M.1
Thall, P.F.2
Ng, C.S.3
Wang, X.4
Wooten, L.5
Siefker-Radtke, A.6
-
37
-
-
70350640904
-
A phase II study of gemcitabine and capecitabine in patients with advanced renal cell cancer
-
Van Veldhuizen PJ, Hussey M, Lara PN Jr, Mack PC, Gandour-Edwards R, Clark JI, et al. A phase II study of gemcitabine and capecitabine in patients with advanced renal cell cancer. Am J Clin Oncol 2009; 32: 453-459.
-
(2009)
Am J Clin Oncol
, vol.32
, pp. 453-459
-
-
Van Veldhuizen, P.J.1
Hussey, M.2
Lara Jr., P.N.3
Mack, P.C.4
Gandour-Edwards, R.5
Clark, J.I.6
-
38
-
-
4844231761
-
Active chemotherapy for sarcomatoid and rapidly progressing renal cell carcinoma
-
DOI 10.1002/cncr.20541
-
Nanus DM, Garino A, Milowsky MI, Larkin M, Dutcher JP. Active chemotherapy for sarcomatoid and rapidly progressing renal cell carcinoma. Cancer 2004; 101:1545-1551. (Pubitemid 39318900)
-
(2004)
Cancer
, vol.101
, Issue.7
, pp. 1545-1551
-
-
Nanus, D.M.1
Garino, A.2
Milowsky, M.I.3
Larkin, M.4
Dutcher, J.P.5
-
39
-
-
65249089759
-
Phase II trial of carboplatin and paclitaxel in papillary renal cell carcinoma
-
Bylow KA, Atkins MB, Posadas EM, Stadler WM, McDermott DF. Phase II trial of carboplatin and paclitaxel in papillary renal cell carcinoma. Clin Genitourin Cancer 2009; 7 (No 1):39-42.
-
(2009)
Clin Genitourin Cancer
, vol.7
, Issue.1
, pp. 39-42
-
-
Bylow, K.A.1
Atkins, M.B.2
Posadas, E.M.3
Stadler, W.M.4
McDermott, D.F.5
-
40
-
-
79959650819
-
Combination of gemcitabine and doxorubicin in rapidly progressive metastatic renal cell carcinoma and/or sarcomatoid renal cell carcinoma
-
Roubaud G, Gross-Goupil M, Wallerand H, de Clermont H, Dilhuydy MS, Ravaud A. Combination of gemcitabine and doxorubicin in rapidly progressive metastatic renal cell carcinoma and/or sarcomatoid renal cell carcinoma. Oncology 2011; 80 (3-4):214-218.
-
(2011)
Oncology
, vol.80
, Issue.3-4
, pp. 214-218
-
-
Roubaud, G.1
Gross-Goupil, M.2
Wallerand, H.3
De Clermont, H.4
Dilhuydy, M.S.5
Ravaud, A.6
-
41
-
-
84869206710
-
A phase II trial of doxorubicin and gemcitabine in renal cell carcinoma with sarcomatoid features: ECOG 8802
-
Haas NB, Lin X, Manola J, Pins M, Liu G, McDermott D, et al. A phase II trial of doxorubicin and gemcitabine in renal cell carcinoma with sarcomatoid features: ECOG 8802. Med Oncol 2011; 29:261-267.
-
(2011)
Med Oncol
, vol.29
, pp. 261-267
-
-
Haas, N.B.1
Lin, X.2
Manola, J.3
Pins, M.4
Liu, G.5
McDermott, D.6
-
42
-
-
84885022299
-
Phase II trial of pemetrexed plus gemcitabine in patients with locally advanced and metastatic nonclear cell renal cell carcinoma
-
Epub ahead of print
-
Richey SL, Tamboli P, Ng CS, Lin E, Lim ZD, Araujo JC, et al. Phase II trial of pemetrexed plus gemcitabine in patients with locally advanced and metastatic nonclear cell renal cell carcinoma. Am J Clin Oncol 2012 [Epub ahead of print].
-
(2012)
Am J Clin Oncol
-
-
Richey, S.L.1
Tamboli, P.2
Ng, C.S.3
Lin, E.4
Lim, Z.D.5
Araujo, J.C.6
-
43
-
-
2142695181
-
Interleukin-2- and interferon alfa-2a-based immunochemotherapy in advanced renal cell carcinoma: A prospectively randomized trial of the German Cooperative Renal Carcinoma Chemoimmunotherapy Group (DGCIN)
-
DOI 10.1200/JCO.2004.06.155
-
Atzpodien J, Kirchner H, Jonas U, Bergmann L, Schott H, Heynemann H, et al. Interleukin-2- and interferon alfa-2a-based immunochemotherapy in advanced renal cell carcinoma: a prospectively randomized trial of the German Cooperative Renal Carcinoma Chemoimmunotherapy Group (DGCIN). J Clin Oncol 2004; 22:1188-1194. (Pubitemid 41079830)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.7
, pp. 1188-1194
-
-
Kirchner, H.1
Jonas, U.2
Bergmann, L.3
Schott, H.4
Heynemann, H.5
Fornara, P.6
Loening, S.A.7
Roigas, J.8
Muller, S.C.9
Bodenstein, H.10
Pomer, S.11
Metzner, B.12
Rebmann, U.13
Oberneder, R.14
Siebels, M.15
Wandert, T.16
Puchberger, T.17
Reitz, M.18
Atzpodien, J.19
-
44
-
-
33747153299
-
Interleukin-2/interferon-α2a/13-retinoic acid-based chemoimmunotherapy in advanced renal cell carcinoma: Results of a prospectively randomised trial of the German Cooperative Renal Carcinoma Chemoimmunotherapy Group (DGCIN)
-
DOI 10.1038/sj.bjc.6603271, PII 6603271
-
Atzpodien J, Kirchner H, Rebmann U, Soder M, Gertenbach U, Siebels M, et al. Interleukin-2/interferon-a2a/13-retinoic acid-based chemoimmunotherapy in advanced renal cell carcinoma: results of a prospectively randomized trial of the German Cooperative Renal Carcinoma Chemoimmunotherapy Group (DGCIN). Br J Cancer 2006; 95:463-469. (Pubitemid 44232555)
-
(2006)
British Journal of Cancer
, vol.95
, Issue.4
, pp. 463-469
-
-
Atzpodien, J.1
Kirchner, H.2
Rebmann, U.3
Soder, M.4
Gertenbach, U.5
Siebels, M.6
Roigas, J.7
Raschke, R.8
Salm, S.9
Schwindl, B.10
Muller, S.C.11
Hauser, S.12
Leiber, C.13
Huland, E.14
Heinzer, H.15
Siemer, S.16
Metzner, B.17
Heynemann, H.18
Fornara, P.19
Reitz, M.20
more..
-
45
-
-
11144358544
-
Interleukin-2, Interferon-α and 5-Fluorouracil Immunotherapy for Metastatic Renal Cell Carcinoma: The All Ireland Experience
-
DOI 10.1016/j.eururo.2003.11.002, PII S0302283803005700
-
O'Brien MF, Rea D, Rogers E, Bredin H, Butler M, Grainger R, et al. Interleukin-2, interferon-a and 5-fluorouracil immunotherapy for metastatic renal cell carcinoma: the all Ireland experience. Eur Urol 2004; 45: 613-619. (Pubitemid 38481689)
-
(2004)
European Urology
, vol.45
, Issue.5
, pp. 613-619
-
-
O'Brien, M.F.1
Rea, D.2
Rogers, E.3
Bredin, H.4
Butler, M.5
Grainger, R.6
McDermott, T.E.D.7
Mullins, G.8
O'Brien, A.9
Twomey, A.10
Thornhill, J.11
-
46
-
-
33847002688
-
Immuno-chemotherapy in metastatic renal cell carcinoma: Long-term results from the Rambam and Linn medical centers, Haifa, Israel
-
Gez E, Rubinov R, Gaitini D, Meretyk S, Best LA, Mashiach T, et al. Immuno-chemotherapy in metastatic renal cell carcinoma: long-term results from the Rambam and Linn medical centers, Haifa, Israel. J Chemother 2007; 19:79-84.
-
(2007)
J Chemother
, vol.19
, pp. 79-84
-
-
Gez, E.1
Rubinov, R.2
Gaitini, D.3
Meretyk, S.4
Best, L.A.5
Mashiach, T.6
-
47
-
-
34748837365
-
Role of chemotherapy with gemcitabine plus 5-fluorouracil and chemoimmunotherapy in metastatic renal cell cancer (mRCC)
-
DOI 10.1097/CJI.0b013e31814fb2ec, PII 0000237120071000000011
-
Buti S, Brighenti M, Bongiovanni C, Buzio C, Chiesa MD, Alberici F, Passalacqua R. Role of chemotherapy with gemcitabine plus 5-fluorouracil and chemoimmunotherapy in metastatic renal cell cancer (mRCC). J Immunother 2007; 30:780-786. (Pubitemid 47480761)
-
(2007)
Journal of Immunotherapy
, vol.30
, Issue.7
, pp. 780-786
-
-
Buti, S.1
Brighenti, M.2
Bongiovanni, C.3
Buzio, C.4
Chiesa, M.D.5
Alberici, F.6
Passalacqua, R.7
-
48
-
-
67651176263
-
Granulocyte macrophage-colony stimulating factor plus interleukin-2 plus a-interferon plus 5-fluorouracil in the treatment of metastatic renal cell cancer
-
Westermann J, Hecker AC, Florcken A, Dorken B, Pezzutto A. Granulocyte macrophage-colony stimulating factor plus interleukin-2 plus a-interferon plus 5-fluorouracil in the treatment of metastatic renal cell cancer. J Immunother 2009; 32:667-675.
-
(2009)
J Immunother
, vol.32
, pp. 667-675
-
-
Westermann, J.1
Hecker, A.C.2
Florcken, A.3
Dorken, B.4
Pezzutto, A.5
-
49
-
-
1842581759
-
Phase II Trial of 5-Fluorouracil and Leucovorin in Combination with Interferon-alpha and Interleukin-2 for Advanced Renal Cell Cancer
-
DOI 10.1097/01.coc.0000046599.52805.00
-
Rathmell KW, Malkowicz SB, Holroyde C, Luginbuhl W, Vaughn DJ. Phase II trial of 5-fluorouracil and leucovorn in combination with interferon-alpha and interleukin-2 for advanced renal cell cancer. Am J Clin Oncol 2004; 27:109-112. (Pubitemid 38451470)
-
(2004)
American Journal of Clinical Oncology: Cancer Clinical Trials
, vol.27
, Issue.2
, pp. 109-112
-
-
Rathmell, W.K.1
Malkowicz, S.B.2
Holroyde, C.3
Luginbuhl, W.4
Vaughn, D.J.5
-
50
-
-
33646575906
-
Interferon-α plus capecitabine and thalidomide in patients with metastatic renal cell carcinoma: A pilot study
-
DOI 10.1007/s10637-005-2938-5
-
Amato JR, Rawat A. Interferon-a plus capecitabine and thalidomide in patients with metastatic renal cell carcinoma: a pilot study. Invest New Drugs 2006; 24:171-175. (Pubitemid 43723892)
-
(2006)
Investigational New Drugs
, vol.24
, Issue.3
, pp. 171-175
-
-
Amato, R.J.1
Rawat, A.2
-
51
-
-
33845868207
-
Phase II trial of capecitabine and rHu-interferon-α-2a in patients with metastatic renal cell carcinoma, limited efficacy, and moderate toxicity
-
DOI 10.1016/j.urolonc.2006.02.016, PII S1078143906000597
-
Segota E, Mekhail T, Olencki T, Hutson TE, Dreicer R, Wacker B, et al. Phase II trial of capecitabine and rHu-interferon-a-2a in patients with metastatic renal cell carcinoma, limited efficacy, and moderate toxicity. Urol Oncol 2007; 25:46-52. (Pubitemid 46027613)
-
(2007)
Urologic Oncology: Seminars and Original Investigations
, vol.25
, Issue.1
, pp. 46-52
-
-
Segota, E.1
Mekhail, T.2
Olencki, T.3
Hutson, T.E.4
Dreicer, R.5
Wacker, B.6
Osterwalder, B.7
Elson, P.8
Zhou, M.9
Bukowski, R.M.10
-
52
-
-
16644368159
-
Combination therapy with capecitabine and interferon alfa-2a in patients with advanced renal cell carcinoma: A phase II study
-
Padrik P, Leppik K, Arak A. Combination therapy with capecitabine and interferon alfa-2a in patients with advanced renal cell carcinoma: a phase II study. Urol Oncol 2004; 22:387-392.
-
(2004)
Urol Oncol
, vol.22
, pp. 387-392
-
-
Padrik, P.1
Leppik, K.2
Arak, A.3
-
53
-
-
0842287223
-
Subcutaneous interleukin-2, interferon alpha-2b and 5-fluorouracil in metastatic renal cell carcinoma as second-line treatment after failure of previous immunotherapy: A phase II trial
-
DOI 10.1038/sj.bjc.6601419
-
Ravaud A, Trufflandier N, Ferriè re JM, Debled M, Palussiè re J, Cany L, et al. Subcutaneous interleukin-2, interferon alpha-2b and 5-fluorouracil in metastatic renal cell carcinoma as second-line treatment after failure of previous immunotherapy: a phase II trial. Br J Cancer 2003; 89: 2213-2218. (Pubitemid 38168002)
-
(2003)
British Journal of Cancer
, vol.89
, Issue.12
, pp. 2213-2218
-
-
Ravaud, A.1
Trufflandier, N.2
Ferriere, J.M.3
Debled, M.4
Palussiere, J.5
Cany, L.6
Gaston, R.7
Mathoulin-Pelissier, S.8
Bui, B.N.9
-
54
-
-
77951914543
-
A phase-II study of combination of pegylated interferon alfa-2a and capecitabine in locally advanced or metastatic renal cell cancer
-
Sunela KL, Koskinen S, Kellokumpu-Lehtinen PL. A phase-II study of combination of pegylated interferon alfa-2a and capecitabine in locally advanced or metastatic renal cell cancer. Cancer Chemother Pharmacol 2010; 66:59-67.
-
(2010)
Cancer Chemother Pharmacol
, vol.66
, pp. 59-67
-
-
Sunela, K.L.1
Koskinen, S.2
Kellokumpu-Lehtinen, P.L.3
-
55
-
-
84866303137
-
Pioglitazone, etoricoxib, interferon-a, and metronomic capecitabine for metastatic renal cell carcinoma: Final results of a prospective phase II trial
-
Walter B, Schrettenbrunner I, Vogelhuber M, Grassinger J, Bross K,Wilke J, et al. Pioglitazone, etoricoxib, interferon-a, and metronomic capecitabine for metastatic renal cell carcinoma: final results of a prospective phase II trial. Med Oncol 2012; 29:799-805.
-
(2012)
Med Oncol
, vol.29
, pp. 799-805
-
-
Walter, B.1
Schrettenbrunner, I.2
Vogelhuber, M.3
Grassinger, J.4
Bross, K.5
Wilke, J.6
-
56
-
-
33746282197
-
Chemoimmunotherapy with low dose vinorelbine and interleukin-2 in treatment of patients with metastatic renal cell carcinoma
-
Mencoboni MP, Tredici S, Varaldo M, Queirolo G, Durand F, Rebella L, et al. Chemoimmunotherapy with low dose vinorelbine and interleukin-2 in treatment of patients with metastatic renal cell carcinoma. Neoplasma 2006; 53:333-336. (Pubitemid 44105940)
-
(2006)
Neoplasma
, vol.53
, Issue.4
, pp. 333-336
-
-
Mencoboni, M.P.1
Tredici, S.2
Varaldo, M.3
Queirolo, G.4
Durand, F.5
Rebella, L.6
Galbusera, V.7
Pannacciulli, I.M.8
Ghio, R.9
-
57
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
DOI 10.1056/NEJMoa032691
-
Hurwitz H, Fehrenbacher L, Novotny W, Cartwright T, Hainsworth J, Heim W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350:2335-2342. (Pubitemid 38702844)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.23
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
Berlin, J.7
Baron, A.8
Griffing, S.9
Holmgren, E.10
Ferrara, N.11
Fyfe, G.12
Rogers, B.13
Ross, R.14
Kabbinavar, F.15
-
58
-
-
62449124416
-
Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first line therapy for non-squamous non-small-cell lung cancer: AVAil
-
Reck M, Von Pawel J, Zatloukal P, Ramlau R, Gorbounova V, Hirsh V, et al. Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first line therapy for non-squamous non-small-cell lung cancer: AVAil. J Clin Oncol 2009; 27:1227-1234.
-
(2009)
J Clin Oncol
, vol.27
, pp. 1227-1234
-
-
Reck, M.1
Von Pawel, J.2
Zatloukal, P.3
Ramlau, R.4
Gorbounova, V.5
Hirsh, V.6
-
59
-
-
37549040613
-
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
-
Miller K, Wang M, Gralow J, Dickler M, Cobleigh M, Perez EA, et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med 2007; 357:2666-2676.
-
(2007)
N Engl J Med
, vol.357
, pp. 2666-2676
-
-
Miller, K.1
Wang, M.2
Gralow, J.3
Dickler, M.4
Cobleigh, M.5
Perez, E.A.6
-
60
-
-
73349120007
-
Independent review of E2100: A phase III trial of bevacizumab plus paclitaxel versus paclitaxel in women with metastatic breast cancer
-
Gray R, Bhattacharya S, Bowden C, Miller K, Comis RL. Independent review of E2100: a phase III trial of bevacizumab plus paclitaxel versus paclitaxel in women with metastatic breast cancer. J Clin Oncol 2009; 27:4966-4972.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4966-4972
-
-
Gray, R.1
Bhattacharya, S.2
Bowden, C.3
Miller, K.4
Comis, R.L.5
-
61
-
-
78650450402
-
ICON7: A phase III gynaecologic cancer intergroup (GCIG) trial of adding bevacizumab to standard chemotherapy in women with newly diagnosed epithelial ovarian, primary peritoneal or fallopian tube cancer [abstract LBA4]
-
Perren T, Swart AM, Pfisterer J, Ledermann JA, Pujade-Lauraine E, Kristensen G, et al. ICON7: a phase III gynaecologic cancer intergroup (GCIG) trial of adding bevacizumab to standard chemotherapy in women with newly diagnosed epithelial ovarian, primary peritoneal or fallopian tube cancer [abstract LBA4]. Ann Oncol 2010; 21 (Suppl):8.
-
(2010)
Ann Oncol
, vol.21
, Issue.SUPPL.
, pp. 8
-
-
Perren, T.1
Swart, A.M.2
Pfisterer, J.3
Ledermann, J.A.4
Pujade-Lauraine, E.5
Kristensen, G.6
-
62
-
-
11844254414
-
Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
-
DOI 10.1126/science.1104819
-
Jain R. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 2005; 307:58-62. (Pubitemid 40093472)
-
(2005)
Science
, vol.307
, Issue.5706
, pp. 58-62
-
-
Jain, R.K.1
-
63
-
-
84859495330
-
Microtubules regulate hypoxia-inducible factor-1a protein trafficking and activity: Implications for taxane therapy
-
Carbonaro M, Escuin D, O'Brate A, Thadani-Mulero M, Giannakakou P. Microtubules regulate hypoxia-inducible factor-1a protein trafficking and activity: implications for taxane therapy. J Biol Chem 2012; 287: 11859-11869.
-
(2012)
J Biol Chem
, vol.287
, pp. 11859-11869
-
-
Carbonaro, M.1
Escuin, D.2
O'Brate, A.3
Thadani-Mulero, M.4
Giannakakou, P.5
-
64
-
-
84859298343
-
Downregulation of PKCzeta in renal cell carcinoma and its clinicopathological implications
-
Pu YS, Huang CY, Chen JY, Kang WY, Lin YC, Shiu YS, et al. Downregulation of PKCzeta in renal cell carcinoma and its clinicopathological implications. J Biomed Sci 2012; 19:39-49.
-
(2012)
J Biomed Sci
, vol.19
, pp. 39-49
-
-
Pu, Y.S.1
Huang, C.Y.2
Chen, J.Y.3
Kang, W.Y.4
Lin, Y.C.5
Shiu, Y.S.6
-
65
-
-
84860260532
-
Inhibition of STAT1 sensitizes renal cell carcinoma cells to radiotherapy and chemotherapy
-
Zhu H, Wang Z, Xu Q, Zhang Y, Zhai Y, Bai J, et al. Inhibition of STAT1 sensitizes renal cell carcinoma cells to radiotherapy and chemotherapy. Cancer Biol Ther 2012; 13:13-18.
-
(2012)
Cancer Biol Ther
, vol.13
, pp. 13-18
-
-
Zhu, H.1
Wang, Z.2
Xu, Q.3
Zhang, Y.4
Zhai, Y.5
Bai, J.6
-
66
-
-
80054760953
-
Impact of cisplatin administration on protein expression levels in renal cell carcinoma: A proteomic analysis
-
Vasko R, Mueller GA, von Jaschke AK, Asif AR, Dihazi H. Impact of cisplatin administration on protein expression levels in renal cell carcinoma: a proteomic analysis. Eur J Pharmacol 2011; 670:50-57.
-
(2011)
Eur J Pharmacol
, vol.670
, pp. 50-57
-
-
Vasko, R.1
Mueller, G.A.2
Von Jaschke, A.K.3
Asif, A.R.4
Dihazi, H.5
-
67
-
-
79952293565
-
L1-CAM expression in ccRCC correlates with shorter patient survival times and confers chemoresistance in renal cell carcinoma cells
-
Doberstein K, Wieland A, Lee SB, Blaheta RA, Wedel S, Moch H, et al. L1-CAM expression in ccRCC correlates with shorter patient survival times and confers chemoresistance in renal cell carcinoma cells. Carcinogenesis 2011; 32:262-270.
-
(2011)
Carcinogenesis
, vol.32
, pp. 262-270
-
-
Doberstein, K.1
Wieland, A.2
Lee, S.B.3
Blaheta, R.A.4
Wedel, S.5
Moch, H.6
-
68
-
-
68849086857
-
Expression of multidrug resistance markers ABCB1 (MDR-1/P-gp) and ABCC1 (MRP-1) in renal cell carcinoma
-
Walsh N, Larkin A, Kennedy S, Connolly L, Ballot J, OoiW, et al. Expression of multidrug resistance markers ABCB1 (MDR-1/P-gp) and ABCC1 (MRP-1) in renal cell carcinoma. BMC Urol 2009; 9:6.
-
(2009)
BMC Urol
, vol.9
, pp. 6
-
-
Walsh, N.1
Larkin, A.2
Kennedy, S.3
Connolly, L.4
Ballot, J.5
Ooi, W.6
-
69
-
-
71549151624
-
Suppression of hypoxia-inducible factor 2alpha restores p53 activity via Hdm2 and reverses chemoresistance of renal carcinoma cells
-
Roberts AM, Watson IR, Evans AJ, Foster DA, Irwin MS, Ohh M. Suppression of hypoxia-inducible factor 2alpha restores p53 activity via Hdm2 and reverses chemoresistance of renal carcinoma cells. Cancer Res 2009; 69:9056-9064.
-
(2009)
Cancer Res
, vol.69
, pp. 9056-9064
-
-
Roberts, A.M.1
Watson, I.R.2
Evans, A.J.3
Foster, D.A.4
Irwin, M.S.5
Ohh, M.6
-
70
-
-
33947155835
-
Connexin 32 potentiates vinblastine-induced cytotoxicity in renal cell carcinoma cells
-
DOI 10.1002/mc.20267
-
Sato H, Senba H, Virgona N, Fukumoto K, Ishida T, Hagiwara H, et al. Connexin 32 potentiates vinblastine-induced cytotoxicity in renal cell carcinoma cells. Mol Carcinog 2007; 46:215-224. (Pubitemid 46399520)
-
(2007)
Molecular Carcinogenesis
, vol.46
, Issue.3
, pp. 215-224
-
-
Sato, H.1
Senba, H.2
Virgona, N.3
Fukumoto, K.4
Ishida, T.5
Hagiwara, H.6
Negishi, E.7
Ueno, K.8
Yamasaki, H.9
Yano, T.10
-
71
-
-
17144399913
-
Inhibition of bcl-2 enhances the efficacy of chemotherapy in renal cell carcinoma
-
DOI 10.1016/j.eururo.2004.11.013
-
Kausch I, Jiang H, Thode B, Doehn C, Krüger S, Jocham D. Inhibition of bcl-2 enhances the efficacy of chemotherapy in renal cell carcinoma. Eur Urol 2005; 47:703-709. (Pubitemid 40521925)
-
(2005)
European Urology
, vol.47
, Issue.5
, pp. 703-709
-
-
Kausch, I.1
Jiang, H.2
Thode, B.3
Doehn, C.4
Kruger, S.5
Jocham, D.6
-
72
-
-
0036244343
-
Expression of genes involved in chemoresistance, proliferation and apoptosis in clinical samples of renal cell carcinoma and correlation with clinical outcome
-
Oudard S, Levalois C, Andrieu JM, Bougaran J, Validire P, Thiounn N, et al. Expression of genes involved in chemoresistance, proliferation and apoptosis in clinical samples of renal cell carcinoma and correlation with clinical outcome. Anticancer Res 2002; 22 (1A):121-128. (Pubitemid 34475285)
-
(2002)
Anticancer Research
, vol.22
, Issue.1
, pp. 121-128
-
-
Oudard, S.1
Levalois, C.2
Andrieu, J.-M.3
Bougaran, J.4
Validire, P.5
Thiounn, N.6
Poupon, M.-F.7
Fourme, E.8
Chevillard, S.9
-
73
-
-
0034870685
-
Chemosensitization of human renal cell cancer using antisense oligonucleotides targeting the antiapoptotic gene clusterin
-
DOI 10.1038/sj.neo.7900174
-
Zellweger T, Miyake H, July LV, Akbari M, Kiyama S, Gleave ME. Chemosensitization of human renal cell cancer using antisense oligonucleotides targeting the antiapoptotic gene clusterin. Neoplasia 2001; 3:360-367. (Pubitemid 32801886)
-
(2001)
Neoplasia
, vol.3
, Issue.4
, pp. 360-367
-
-
Zellweger, T.1
Miyake, H.2
July, L.V.3
Akbari, M.4
Kiyama, S.5
Gleave, M.E.6
-
74
-
-
0030213563
-
Expression patterns of multidrug-resistance (mdr1), multidrug resistance-associated protein (MRP), glutathione-S-transferase-π (GST-π) and DNA topoisomerase II (Topo II) genes in renal cell carcinomas and normal kidney
-
KimWJ, Kakehi Y, Kinoshita H, Arao S, Fukumoto M, Yoshida O. Expression patterns of multidrug-resistance (MDR1), multidrug resistance-associated protein (MRP),glutathione-S-transferase-pi (GST-pi) and DNA topoisomerase II (Topo II) genes in renal cell carcinomas and normal kidney. J Urol 1996; 156 (Pt 1):506-511. (Pubitemid 126445369)
-
(1996)
Journal of Urology
, vol.156
, Issue.2
, pp. 506-511
-
-
Kim, W.-J.1
Kakehi, Y.2
Kinoshita, H.3
Arao, S.4
Fukumoto, M.5
Yoshida, O.6
-
75
-
-
0029551181
-
Dexverapamil to modulate vinblastine resistance in metastatic renal cell carcinoma
-
Mickisch GH, Noordzij MA, vd Gaast A, Gebreamlack P, Köhrmann KU, Mogler-Drautz E, et al. Dexverapamil to modulate vinblastine resistance in metastatic renal cell carcinoma. J Cancer Res Clin Oncol 1995; 121 (Suppl 3):R11-R16. (Pubitemid 26253215)
-
(1995)
Journal of Cancer Research and Clinical Oncology, Supplement
, vol.121
, Issue.3
-
-
Mickisch, G.H.1
Noordzij, M.A.2
Gaast, A.3
Gebreamlack, P.4
Kohrmann, K.U.5
Mogler-Drautz, E.6
Kupper, H.7
Schroder, F.H.8
-
76
-
-
0029049257
-
Phase I/II trial of dexverapamil plus vinblastine for patients with advanced renal cell carcinoma
-
Motzer RJ, Lyn P, Fischer P, Lianes P, Ngo RL, Cordon-Cardo C, O'Brien JP. Phase I/II trial of dexverapamil plus vinblastine for patients with advanced renal cell carcinoma. J Clin Oncol 1995; 13:1958-1965.
-
(1995)
J Clin Oncol
, vol.13
, pp. 1958-1965
-
-
Motzer, R.J.1
Lyn, P.2
Fischer, P.3
Lianes, P.4
Ngo, R.L.5
Cordon-Cardo, C.6
O'Brien, J.P.7
-
77
-
-
0027181003
-
Expression of resistance factors (P-glycoprotein, glutathione S- transferase-π, and topoisomerase II) and their interrelationship to proto- oncogene products in renal cell carcinomas
-
Volm M, Kästel M, Mattern J, Efferth T. Expression of resistance factors (P-glycoprotein, glutathione S-transferase-pi, and topoisomerase II) and their interrelationship to proto-oncogene products in renal cell carcinomas. Cancer 1993; 71:3981-3987. (Pubitemid 23172981)
-
(1993)
Cancer
, vol.71
, Issue.12
, pp. 3981-3987
-
-
Volm, M.1
Kastel, M.2
Mattern, J.3
Efferth, T.4
-
78
-
-
0028709073
-
Chemoresistance of renal cell carcinoma: 1986-1994
-
Mickisch GH. Chemoresistance of renal cell carcinoma: 1986-1994. World J Urol 1994; 12:214-223.
-
(1994)
World J Urol
, vol.12
, pp. 214-223
-
-
Mickisch, G.H.1
-
79
-
-
0032127244
-
Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5 fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue
-
DOI 10.1016/S0959-8049(98)00058-6, PII S0959804998000586
-
Miwa M, Ura M, Nishida M, Sawada N, Ishikawa T, Mori K, et al. Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue. Eur J Cancer 1998; 34:1274-1281. (Pubitemid 28342121)
-
(1998)
European Journal of Cancer
, vol.34
, Issue.8
, pp. 1274-1281
-
-
Miwa, M.1
Ura, M.2
Nishida, M.3
Sawada, N.4
Ishikawa, T.5
Mori, K.6
Shimma, N.7
Umeda, I.8
Ishitsuka, H.9
-
80
-
-
0023115642
-
A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukine-2 or high-dose interleukine-2 alone
-
Rosenberg SA, Lotze MT, Muul LM, Chang AE, Avis FP, Leitman S, et al. A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukine-2 or high-dose interleukine-2 alone. N Engl J Med 1987; 316:898-905.
-
(1987)
N Engl J Med
, vol.316
, pp. 898-905
-
-
Rosenberg, S.A.1
Lotze, M.T.2
Muul, L.M.3
Chang, A.E.4
Avis, F.P.5
Leitman, S.6
-
81
-
-
8944239882
-
Subcutaneous recombinant interleukin-2 (rIL-2) in out-patients with metastatic renal cell carcinoma. Results of a multicenter SCAPP1 trial
-
Tourani JM, Lucas V, Mayeur D, Dufour B, DiPalma M, Boaziz C, et al. Subcutaneous recombinant interleukin-2 (rIL-2) in outpatient treatment with metastatic renal cell carcinoma. Results of a multicenter SCAPP trial. Ann Oncol 1996; 7:525-528. (Pubitemid 26232961)
-
(1996)
Annals of Oncology
, vol.7
, Issue.5
, pp. 525-528
-
-
Tourani, J.M.1
Lucas, V.2
Mayeur, D.3
Dufour, B.4
Di Palma, M.5
Boaziz, C.6
Grise, P.7
Varette, C.8
Pavlovitch, J.M.9
Pujade-Lauraine, E.10
Larregain, D.11
Ecstein, E.12
Untereiner, M.13
Vuillemin, E.14
Merran, S.15
Andrieu, J.M.16
-
83
-
-
0038235998
-
Increased sensitivity to gemcitabine of P-glycoprotein and multidrug resistance-associated protein-overexpressing human cancer cell lines
-
DOI 10.1038/sj.bjc.6601011
-
Bergman AM, Pinedo hM, Talianidis I, Veerman G, Loves WJ, van der Wilt CL, Peters GJ. Increased sensitivity to gemcitabine of P-glycoprotein and multidrug resistance-associated proteinoverexpressing human cancer cell lines. Br J Cancer 2003; 88:1963-1970. (Pubitemid 36829675)
-
(2003)
British Journal of Cancer
, vol.88
, Issue.12
, pp. 1963-1970
-
-
Bergman, A.M.1
Pinedo, H.M.2
Talianidis, I.3
Veerman, G.4
Loves, W.J.P.5
Van Der Wilt, C.L.6
Peters, G.J.7
-
84
-
-
0032772880
-
Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma
-
Motzer RJ, Mazumdar M, Bacik J, Berg W, Amsterdam A, Ferrara J. Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma. J Clin Oncol 1999; 17:2530-2540. (Pubitemid 29368255)
-
(1999)
Journal of Clinical Oncology
, vol.17
, Issue.8
, pp. 2530-2540
-
-
Motzer, R.J.1
Mazumdar, M.2
Bacik, J.3
Berg, W.4
Amsterdam, A.5
Ferrara, J.6
-
85
-
-
33646865114
-
Randomized phase III trial of the multi-kinase inhibitor sorafenib (BAY 43- 9006) in patients with advanced renal cell carcinoma [abstract 794]
-
Escudier B, Szczylik C, Eisen T, Stadler WM, Schwartz B, Shan RM. Randomized phase III trial of the multi-kinase inhibitor sorafenib (BAY 43- 9006) in patients with advanced renal cell carcinoma [abstract 794]. Eur J Cancer Suppl 2005; 3:226.
-
(2005)
Eur J Cancer Suppl
, vol.3
, pp. 226
-
-
Escudier, B.1
Szczylik, C.2
Eisen, T.3
Stadler, W.M.4
Schwartz, B.5
Shan, R.M.6
-
86
-
-
33644833910
-
Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma
-
DOI 10.1200/JCO.2005.02.2574
-
Motzer RJ, Michaelson MD, Redman BG, Hudes GR,Wilding G, Figlin RA, et al. Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma. J Clin Oncol 2006; 24: 16-24. (Pubitemid 46630489)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.1
, pp. 16-24
-
-
Motzer, R.J.1
Michaelson, M.D.2
Redman, B.G.3
Hudes, G.R.4
Wilding, G.5
Figlin, R.A.6
Ginsberg, M.S.7
Kim, S.T.8
Baum, C.M.9
DePrimo, S.E.10
Li, J.Z.11
Bello, C.L.12
Theuer, C.P.13
George, D.J.14
Rini, B.I.15
-
87
-
-
78650839264
-
Non-clear cell advanced kidney cancer: Is there a gold standard
-
Sanchez P, Calvo E, Duran I. Non-clear cell advanced kidney cancer: is there a gold standard? Anticancer Drugs 2011; 22 (Suppl 1):S9-S14.
-
(2011)
Anticancer Drugs
, vol.22
, Issue.SUPPL. 1
-
-
Sanchez, P.1
Calvo, E.2
Duran, I.3
-
89
-
-
1842529797
-
Sarcomatoid Renal Cell Carcinoma: An Examination of Underlying Histologic Subtype and an Analysis of Associations with Patient Outcome
-
DOI 10.1097/00000478-200404000-00002
-
Cheville JC, Lohse CM, Zincke H, Weaver AL, Leibovich BC, Frank I, Blute ML. Sarcomatoid renal cell carcinoma: an examination of underlying histologic subtype and an analysis of associations with patient outcome. Am J Surg Pathol 2004; 28:435-441. (Pubitemid 38436516)
-
(2004)
American Journal of Surgical Pathology
, vol.28
, Issue.4
, pp. 435-441
-
-
Cheville, J.C.1
Lohse, C.M.2
Zincke, H.3
Weaver, A.L.4
Leibovich, B.C.5
Frank, I.6
Blute, M.L.7
-
90
-
-
0035116618
-
Sarcomatoid differentiation in renal cell carcinoma: A study of 101 cases
-
DOI 10.1097/00000478-200103000-00001
-
De Peralta-Venturina M, Moch H, Amin M, Tamboli P, Hailemariam S, Mihatsch M, et al. Sarcomatoid differentiation in renal cell carcinoma: a study of 101 cases. Am J Surg Pathol 2001; 25:275-284. (Pubitemid 32174196)
-
(2001)
American Journal of Surgical Pathology
, vol.25
, Issue.3
, pp. 275-284
-
-
De Peralta-Venturina, M.1
Moch, H.2
Amin, M.3
Tamboli, P.4
Hailemariam, S.5
Mihatsch, M.6
Javidan, J.7
Stricker, H.8
Ro, J.Y.9
Amin, M.B.10
-
91
-
-
84655165029
-
Long-term survival of patients with sarcomatoid renal cell cancer treated with chemotherapy
-
Dutcher JP, Nanus DM. Long-term survival of patients with sarcomatoid renal cell cancer treated with chemotherapy. Med Oncol 2011; 28: 1530-1533.
-
(2011)
Med Oncol
, vol.28
, pp. 1530-1533
-
-
Dutcher, J.P.1
Nanus, D.M.2
-
92
-
-
84892671295
-
NCCN Clinical Practice Guidelines in Oncology
-
Motzer RJ, Agarwal N, Beard C, Bhayani S, Bolger GB, Buyyounouski MK, et al. NCCN Clinical Practice Guidelines in Oncology. Kidney Cancer 2012; 1:8-22.
-
(2012)
Kidney Cancer
, vol.1
, pp. 8-22
-
-
Motzer, R.J.1
Agarwal, N.2
Beard, C.3
Bhayani, S.4
Bolger, G.B.5
Buyyounouski, M.K.6
-
94
-
-
0026326717
-
Recombinant interleukin-2 in metastatic renal cell carcinoma - A European multicentre phase II study
-
Von der Maase H, Geertsen P, Tatcher N, Jasmin C, Mercatello A, Fossa SD, et al. Recombinant interleukin-2 in metastatic renal cell carcinoma - a European multicentre phase II study. Eur J Cancer 1991; 27:1583-1589.
-
(1991)
Eur J Cancer
, vol.27
, pp. 1583-1589
-
-
Von Der Maase, H.1
Geertsen, P.2
Tatcher, N.3
Jasmin, C.4
Mercatello, A.5
Fossa, S.D.6
-
95
-
-
0023680153
-
Synergistic antitumor effects of combination immunotherapy with recombinant interleukin-2 and recombinant hybrid alpha-interferon in the treatment of established murine hepatic metastases
-
Cameron RB, McIntosh JK, Rosenberg SA. Synergistic antitumor effects of combination immunotherapy with recombinant interleukin-2 and recombinant hybrid alpha-interferon in the treatment of established murine hepatic metastases. Cancer Res 1988; 58:5810-5817.
-
(1988)
Cancer Res
, vol.58
, pp. 5810-5817
-
-
Cameron, R.B.1
McIntosh, J.K.2
Rosenberg, S.A.3
-
96
-
-
0034046892
-
Phase II trial of weekly intravenous gemcitabine with continuous infusion fluorouracil in patients with metastatic renal cell cancer
-
Rini BI, Vogelzang NJ, Dumas MC, et al. Phase II trial of weekly intravenous gemcitabine with continuous infusion fluorouracil in patients with metastatic renal cell cancer. J Clin Oncol 2000; 18:2419-2426. (Pubitemid 30415829)
-
(2000)
Journal of Clinical Oncology
, vol.18
, Issue.12
, pp. 2419-2426
-
-
Rini, B.I.1
Vogelzang, N.J.2
Dumas, M.C.3
Wade III, J.L.4
Taber, D.A.5
Stadler, W.M.6
-
97
-
-
58149178174
-
Phase I/II trial of 5-fluorouracil and noncytotoxic dose level of suramin in patients with metastatic renal cell carcinoma
-
George S, Dreicer R, Au JL, Shen T, Rini BI, Roman S, et al. Phase I/II trial of 5-fluorouracil and noncytotoxic dose level of suramin in patients with metastatic renal cell carcinoma. Clin Genitourin Cancer 2008; 6:79-85.
-
(2008)
Clin Genitourin Cancer
, vol.6
, pp. 79-85
-
-
George, S.1
Dreicer, R.2
Au, J.L.3
Shen, T.4
Rini, B.I.5
Roman, S.6
-
98
-
-
38049026252
-
A phase I/II study of GTI-2040 and capecitabine in patients with renal cell carcinoma
-
Stadler WM, Desai AA, Quinn DI, Bukowski R, Poiesz B, Kardinal CG, et al. A phase I/II study of GTI-2040 and capecitabine in patients with renal cell carcinoma. Cancer Chemother Pharmacol 2008; 61:689-694.
-
(2008)
Cancer Chemother Pharmacol
, vol.61
, pp. 689-694
-
-
Stadler, W.M.1
Desai, A.A.2
Quinn, D.I.3
Bukowski, R.4
Poiesz, B.5
Kardinal, C.G.6
-
99
-
-
77950312919
-
Activity of a multitargeted chemo-switch regimen (sorafenib, gemcitabine and metronomic capecitabine) in metastatic renal-cell carcinoma: A phase 2 study (SOGUG-02-06)
-
Bellmunt J, Trigo JM, Calvo E, Carles J, Pé rez-Gracia JL, Rubió J, et al. Activity of a multitargeted chemo-switch regimen (sorafenib, gemcitabine and metronomic capecitabine) in metastatic renal-cell carcinoma: a phase 2 study (SOGUG-02-06). Lancet Oncol 2010; 11:350-357.
-
(2010)
Lancet Oncol
, vol.11
, pp. 350-357
-
-
Bellmunt, J.1
Trigo, J.M.2
Calvo, E.3
Carles, J.4
Pé Rez-Gracia, J.L.5
Rubió, J.6
-
100
-
-
77955451553
-
Sorafenib after combination therapy with gemcitabine plus doxorubicine in patients with sarcomatoid renal cell carcinoma: A prospective evaluation
-
Staehler M, Haseke N, Roosen A, Stadler T, Bader M, Siebels M, et al. Sorafenib after combination therapy with gemcitabine plus doxorubicine in patients with sarcomatoid renal cell carcinoma: a prospective evaluation. Eur J Med Res 2010; 14:287-291.
-
(2010)
Eur J Med Res
, vol.14
, pp. 287-291
-
-
Staehler, M.1
Haseke, N.2
Roosen, A.3
Stadler, T.4
Bader, M.5
Siebels, M.6
-
101
-
-
79952253825
-
Treatment of metastatic renal cell carcinoma patients with the combination of gemcitabine, capecitabine and bevacizumab at a tertiary cancer centre
-
Jonasch E, Lal LS, Atkinson BJ, Byfield SD, Miller LA, Pagliaro LC, et al. Treatment of metastatic renal cell carcinoma patients with the combination of gemcitabine, capecitabine and bevacizumab at a tertiary cancer centre. BJU Int 2010; 107:741-748.
-
(2010)
BJU Int
, vol.107
, pp. 741-748
-
-
Jonasch, E.1
Lal, L.S.2
Atkinson, B.J.3
Byfield, S.D.4
Miller, L.A.5
Pagliaro, L.C.6
-
102
-
-
55249088595
-
Phase II studies of antiangiogenic four drug regimens for the treatment of advanced renal cell carcinoma: FUNIL-retinoid and the FUNIL-thalidomide protocols
-
Pacheco AV, Rasila K, Lee SJ, Rabinowitz I, Elias L, Lee FC, Verschraegen CF. Phase II studies of antiangiogenic four drug regimens for the treatment of advanced renal cell carcinoma: FUNIL-retinoid and the FUNIL-thalidomide protocols. Urol Oncol 2007; 26:610-615.
-
(2007)
Urol Oncol
, vol.26
, pp. 610-615
-
-
Pacheco, A.V.1
Rasila, K.2
Lee, S.J.3
Rabinowitz, I.4
Elias, L.5
Lee, F.C.6
Verschraegen, C.F.7
-
103
-
-
77955176213
-
Dose finding trial of a combined regimen with bevacizumab, immunotherapy and chemotherapy in patients with metastatic renal cell cancer: An Italian Oncology Group for Clinical Research (GOIRC) study
-
Buti S, Lazzarelli S, Chiesa MD, Simonelli C, Re GL, Lheshi A, et al. Dose finding trial of a combined regimen with bevacizumab, immunotherapy and chemotherapy in patients with metastatic renal cell cancer: an Italian Oncology Group for Clinical Research (GOIRC) study. J Immunother 2010; 33:735-741.
-
(2010)
J Immunother
, vol.33
, pp. 735-741
-
-
Buti, S.1
Lazzarelli, S.2
Chiesa, M.D.3
Simonelli, C.4
Re, G.L.5
Lheshi, A.6
-
104
-
-
3242688711
-
A phase I/II study of infusional vinblastine with the P-glycoprotein antagonist valspodar (PSC 833) in renal cell carcinoma
-
DOI 10.1158/1078-0432.CCR-0829-03
-
Bates SE, Bakke S, Kang M, Robey RW, Zhai S, Thambi P, et al. A phase I/II study of infusional vinblastine with the P-glycoprotein antagonist valspodar (PSC 833) in renal cell carcinoma. Clin Cancer Res 2004; 10:4724-4733. (Pubitemid 38955523)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.14
, pp. 4724-4733
-
-
Bates, S.E.1
Bakke, S.2
Kang, M.3
Robey, R.W.4
Zhai, S.5
Thambi, P.6
Chen, C.7
Patil, S.8
Smith, T.9
Steinberg, S.M.10
Merino, M.11
Goldspiel, B.12
Meadows, B.13
Stein, W.D.14
Choyke, P.15
Balis, F.16
Figg, W.D.17
Fojo, T.18
-
105
-
-
50649099256
-
Clinical effect and future considerations for molecularlytargeted therapy in renal cell carcinoma
-
Rini BI, Flaherty K. Clinical effect and future considerations for molecularlytargeted therapy in renal cell carcinoma. Urol Oncol 2008; 26:543-549.
-
(2008)
Urol Oncol
, vol.26
, pp. 543-549
-
-
Rini, B.I.1
Flaherty, K.2
-
106
-
-
0038311878
-
Immunotherapy for renal cell carcinoma
-
DOI 10.1016/S0302-2838(03)00191-X
-
Bleumer I, Oosterwijk E, De Mulder P, Mulders PF. Immunotherapy for renal cell carcinoma. Eur Urol 2003; 44:65-75. (Pubitemid 36741377)
-
(2003)
European Urology
, vol.44
, Issue.1
, pp. 65-75
-
-
Bleumer, I.1
Oosterwijk, E.2
De Mulder, P.3
Mulders, P.F.A.4
-
107
-
-
0034119151
-
Novel investigative approaches for advanced renal cell carcinoma
-
Berg WJ, Divgi CR, Nanus DM, Motzer RJ. Novel investigative approaches for advanced renal cell carcinoma. Semin Oncol 2000; 27:234-239. (Pubitemid 30205378)
-
(2000)
Seminars in Oncology
, vol.27
, Issue.2
, pp. 234-239
-
-
Berg, W.J.1
Divgi, C.R.2
Nanus, D.M.3
Motzer, R.J.4
-
108
-
-
0030828684
-
Ribonucleotide reductase R2 gene expression and changes in drug sensitivity and genome stability
-
Huang A, Fan H, Taylor WR,Wright JA. Ribonuclotide reductase R2 gene expression and changes in drug sensitivity and genome stability. Cancer Res 1997; 57:4876-4881. (Pubitemid 27468997)
-
(1997)
Cancer Research
, vol.57
, Issue.21
, pp. 4876-4881
-
-
Huang, A.1
Fan, H.2
Taylor, W.R.3
Wright, J.A.4
-
109
-
-
0019993898
-
Clinical pharmacological studies of concurrent infusion of 5-fluorouracil and thymidine in treatment of colorectal carcinomas
-
Au JL, Rustum YM, Ledesma EJ, Mittelman A, Creaven PJ. Clinical pharmacological studies of concurrent infusion of 5-fluorouracil and thymidine in treatment of colorectal carcinomas. Cancer Res 1982; 42:2930-2937. (Pubitemid 12085770)
-
(1982)
Cancer Research
, vol.42
, Issue.7
, pp. 2930-2937
-
-
Au, J.L.S.1
Rustum, Y.M.2
Ledesma, E.J.3
-
110
-
-
0036881871
-
ABC transporters and inhibitors: New targets, new agents
-
Leonard GD, Polgar O, Bates SE. ABC transporters and inhibitors: new targets, new agents. Curr Opin Investig Drugs 2002; 3:1652-1659. (Pubitemid 36266743)
-
(2002)
Current Opinion in Investigational Drugs
, vol.3
, Issue.11
, pp. 1652-1659
-
-
Leonard, G.D.1
Polgar, O.2
Bates, S.E.3
-
111
-
-
82255167661
-
Phase I-II study of everolimus and low dose oral cyclophosphamide in patients with metastatic renal cell cancer
-
Huijts CM, Santegoets SJ, van den Eertwegh AJ, Pijpers LS, Haanen JB, de Gruijl TD, et al. Phase I-II study of everolimus and low dose oral cyclophosphamide in patients with metastatic renal cell cancer. BMC Cancer 2011; 11:505.
-
(2011)
BMC Cancer
, vol.11
, pp. 505
-
-
Huijts, C.M.1
Santegoets, S.J.2
Van Den Eertwegh, A.J.3
Pijpers, L.S.4
Haanen, J.B.5
De Gruijl, T.D.6
-
112
-
-
0042343801
-
A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
-
DOI 10.1056/NEJMoa021491
-
Yang JC, Haworth L, Sherry RM, Hwu P, Schwartzentruber DJ, Topalian SL, et al. A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N Engl J Med 2003; 349:427-434. (Pubitemid 36910021)
-
(2003)
New England Journal of Medicine
, vol.349
, Issue.5
, pp. 427-434
-
-
Yang, J.C.1
Haworth, L.2
Sherry, R.M.3
Hwu, P.4
Schwartzentruber, D.J.5
Topalian, S.L.6
Steinberg, S.M.7
Chen, H.X.8
Rosenberg, S.A.9
-
113
-
-
1542398693
-
Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma
-
DOI 10.1200/JCO.2004.08.185
-
Atkins MB, Hidalgo M, Stadler WM, Logan TF, Dutcher JP, Hudes GR, et al. Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma. J Clin Oncol 2004; 22:909-918. (Pubitemid 41103603)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.5
, pp. 909-918
-
-
Atkins, M.B.1
Hidalgo, M.2
Stadler, W.M.3
Logan, T.F.4
Dutcher, J.P.5
Hudes, G.R.6
Park, Y.7
Liou, S.-H.8
Marshall, B.9
Boni, J.P.10
Dukart, G.11
Sherman, M.L.12
-
114
-
-
33744984843
-
Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma
-
DOI 10.1200/JCO.2005.03.6723
-
Ratain MJ, Eisen T, Stadler WM, Flaherty KT, Kaye SB, Rosner GL, et al. Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma. J Clin Oncol 2006; 24:2505-2512. (Pubitemid 46630627)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.16
, pp. 2505-2512
-
-
Ratain, M.J.1
Eisen, T.2
Stadler, W.M.3
Flaherty, K.T.4
Kaye, S.B.5
Rosner, G.L.6
Gore, M.7
Desai, A.A.8
Patnaik, A.9
Xiong, H.Q.10
Rowinsky, E.11
Abbruzzese, J.L.12
Xia, C.13
Simantov, R.14
Schwartz, B.15
O'Dwyer, P.J.16
-
115
-
-
35648938219
-
Randomized phase II study of erlotinib combined with bevacizumab compared with bevacizumab alone in metastatic renal cell cancer
-
DOI 10.1200/JCO.2007.11.5154
-
Bukowski RM, Kabbinavar FF, Figlin RA, et al. Randomized phase II study of erlotinib combined with bevacizumab compared with bevacizumab alone in metastatic renal cell cancer. J Clin Oncol 2007; 25:4536-4541. (Pubitemid 350035309)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.29
, pp. 4536-4541
-
-
Bukowski, R.M.1
Kabbinavar, F.F.2
Figlin, R.A.3
Flaherty, K.4
Srinivas, S.5
Vaishampayan, U.6
Drabkin, H.A.7
Dutcher, J.8
Ryba, S.9
Xia, Q.10
Scappaticci, F.A.11
McDermott, D.12
-
116
-
-
44249127263
-
Lapatinib versus hormone therapy in patients with advanced renal cell carcinoma: A randomized phase III clinical trial
-
Ravaud A, Hawkins R, Gardner JP, von der Maase H, Zantl N, Harper P, et al. Lapatinib versus hormone therapy in patients with advanced renal cell carcinoma: a randomized phase III clinical trial. J Clin Oncol 2008; 26:2285-2291.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2285-2291
-
-
Ravaud, A.1
Hawkins, R.2
Gardner, J.P.3
Von Der Maase, H.4
Zantl, N.5
Harper, P.6
-
117
-
-
75749090050
-
Efficacy and safety of pazopanib in patients with metastatic renal cell carcinoma
-
Hutson TE, Davis ID, Machiels JP, De Souza PL, Rottey S, Hong BF, et al. Efficacy and safety of pazopanib in patients with metastatic renal cell carcinoma. J Clin Oncol 2010; 28:475-480.
-
(2010)
J Clin Oncol
, vol.28
, pp. 475-480
-
-
Hutson, T.E.1
Davis, I.D.2
Machiels, J.P.3
De Souza, P.L.4
Rottey, S.5
Hong, B.F.6
-
118
-
-
74549209552
-
Upfront, randomized, phase 2 trial of sorafenib versus sorafenib and lowdose interferon alfa in patients with advanced renal cell carcinoma: Clinical and biomarker analysis
-
Jonasch E, Corn P, Pagliaro LC,Warneke CL, Johnson MM, Tamboli P, et al. Upfront, randomized, phase 2 trial of sorafenib versus sorafenib and lowdose interferon alfa in patients with advanced renal cell carcinoma: clinical and biomarker analysis. Cancer 2010; 116:57-65.
-
(2010)
Cancer
, vol.116
, pp. 57-65
-
-
Jonasch, E.1
Corn, P.2
Pagliaro, L.C.3
Warneke, C.L.4
Johnson, M.M.5
Tamboli, P.6
-
119
-
-
78349284842
-
Vaccination of metastatic renal cancer patients with MVA-5T4: A randomized, double-blind, placebo-controlled phase III study
-
Amato RJ, Hawkins RE, Kaufman HL, Thompson JA, Tomczak P, Szczylik C, et al. Vaccination of metastatic renal cancer patients with MVA-5T4: a randomized, double-blind, placebo-controlled phase III study. Clin Cancer Res 2010; 16:5539-5547.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 5539-5547
-
-
Amato, R.J.1
Hawkins, R.E.2
Kaufman, H.L.3
Thompson, J.A.4
Tomczak, P.5
Szczylik, C.6
-
120
-
-
82755183572
-
Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): A randomised phase 3 trial
-
Rini BI, Escudier B, Tomczak P, Kaprin A, Szczylik C, Hutson TE, et al. Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial. Lancet 2011; 378:1931-1939.
-
(2011)
Lancet
, vol.378
, pp. 1931-1939
-
-
Rini, B.I.1
Escudier, B.2
Tomczak, P.3
Kaprin, A.4
Szczylik, C.5
Hutson, T.E.6
-
121
-
-
79954438593
-
Sorafenib with interleukin-2 vs. sorafenib alone in metastatic renal cell carcinoma: The ROSORC trial
-
Procopio G, Verzoni E, Bracarda S, Ricci S, Sacco C, Ridolfi L, et al. Sorafenib with interleukin-2 vs. sorafenib alone in metastatic renal cell carcinoma: the ROSORC trial. Br J Cancer 2011; 104:1256-1261.
-
(2011)
Br J Cancer
, vol.104
, pp. 1256-1261
-
-
Procopio, G.1
Verzoni, E.2
Bracarda, S.3
Ricci, S.4
Sacco, C.5
Ridolfi, L.6
-
122
-
-
79959549917
-
Temsirolimus and bevacizumab, or sunitinib, or interferon alfa and bevacizumab for patients with advanced renal cell carcinoma (TORAVA): A randomised phase 2 trial
-
Né grier S, Gravis G, Pé rol D, Chevreau C, Delva R, Bay JO, et al. Temsirolimus and bevacizumab, or sunitinib, or interferon alfa and bevacizumab for patients with advanced renal cell carcinoma (TORAVA): a randomised phase 2 trial. Lancet Oncol 2011; 12:673-680.
-
(2011)
Lancet Oncol
, vol.12
, pp. 673-680
-
-
Né Grier, S.1
Gravis, G.2
Pé Rol, D.3
Chevreau, C.4
Delva, R.5
Bay, J.O.6
-
123
-
-
84860355062
-
Randomized phase II trial of sunitinib on an intermittent versus continuous dosing schedule as first-line therapy for advanced renal cell carcinoma
-
Motzer RJ, Hutson TE, Olsen MR, Hudes GR, Burke JM, Edenfield WJ, et al. Randomized phase II trial of sunitinib on an intermittent versus continuous dosing schedule as first-line therapy for advanced renal cell carcinoma. J Clin Oncol 2012; 30:1371-1377.
-
(2012)
J Clin Oncol
, vol.30
, pp. 1371-1377
-
-
Motzer, R.J.1
Hutson, T.E.2
Olsen, M.R.3
Hudes, G.R.4
Burke, J.M.5
Edenfield, W.J.6
-
124
-
-
84863755452
-
Antitumor activity and safety of tivozanib (AV-951) in a phase II randomized discontinuation trial in patients with renal cell carcinoma
-
Nosov DA, Esteves B, Lipatov ON, Lyulko AA, Anischenko AA, Chacko RT, et al. Antitumor activity and safety of tivozanib (AV-951) in a phase II randomized discontinuation trial in patients with renal cell carcinoma. J Clin Oncol 2012; 30:1678-1685.
-
(2012)
J Clin Oncol
, vol.30
, pp. 1678-1685
-
-
Nosov, D.A.1
Esteves, B.2
Lipatov, O.N.3
Lyulko, A.A.4
Anischenko, A.A.5
Chacko, R.T.6
-
125
-
-
84857052966
-
Cediranib monotherapy in patients with advanced renal cell carcinoma: Results of a randomised phase II study
-
Mulders P, Hawkins R, Nathan P, de Jong I, Osanto S, Porfiri E, et al. Cediranib monotherapy in patients with advanced renal cell carcinoma: results of a randomised phase II study. Eur J Cancer 2012; 48:527-537.
-
(2012)
Eur J Cancer
, vol.48
, pp. 527-537
-
-
Mulders, P.1
Hawkins, R.2
Nathan, P.3
De Jong, I.4
Osanto, S.5
Porfiri, E.6
-
126
-
-
84870659220
-
AMG 386 in combination with sorafenib in patients with metastatic clear cell carcinoma of the kidney: A randomized, double-blind, placebocontrolled, phase 2 study
-
Rini B, Szczylik C, Tannir NM, Koralewski P, Tomczak P, Deptala A, et al. AMG 386 in combination with sorafenib in patients with metastatic clear cell carcinoma of the kidney: a randomized, double-blind, placebocontrolled, phase 2 study. Cancer 2012; 118:6152-6161.
-
(2012)
Cancer
, vol.118
, pp. 6152-6161
-
-
Rini, B.1
Szczylik, C.2
Tannir, N.M.3
Koralewski, P.4
Tomczak, P.5
Deptala, A.6
-
127
-
-
84871923308
-
Could interferon still play a role in metastatic renal cell carcinoma? A randomized study of two schedules of sorafenib plus interferon-alpha 2a (RAPSODY)
-
Bracarda S, Porta C, Boni C, Santoro A, Mucciarini C, Pazzola A, et al. Could interferon still play a role in metastatic renal cell carcinoma? A randomized study of two schedules of sorafenib plus interferon-alpha 2a (RAPSODY). Eur Urol 2013; 63:254-261.
-
(2013)
Eur Urol
, vol.63
, pp. 254-261
-
-
Bracarda, S.1
Porta, C.2
Boni, C.3
Santoro, A.4
Mucciarini, C.5
Pazzola, A.6
-
128
-
-
37849001813
-
Efficacy of sunitinib and sorafenib in metastatic papillary and chromophobe renal cell carcinoma
-
Choueiri TK, Plantade A, Elson P, Negrier S, Ravaud A, Oudard S, et al. Efficacy of sunitinib and sorafenib in metastatic papillary and chromophobe renal cell carcinoma. J Clin Oncol 2008; 26:127-131.
-
(2008)
J Clin Oncol
, vol.26
, pp. 127-131
-
-
Choueiri, T.K.1
Plantade, A.2
Elson, P.3
Negrier, S.4
Ravaud, A.5
Oudard, S.6
-
129
-
-
67651201656
-
Safety and efficacy of sunitinib for metastatic renal-cell carcinoma: An expanded-access trial
-
Gore ME, Szczylik C, Porta C, Bracarda S, Bjarnason GA, Oudard S, et al. Safety and efficacy of sunitinib for metastatic renal-cell carcinoma: an expanded-access trial. Lancet Oncol 2009; 10:757-763.
-
(2009)
Lancet Oncol
, vol.10
, pp. 757-763
-
-
Gore, M.E.1
Szczylik, C.2
Porta, C.3
Bracarda, S.4
Bjarnason, G.A.5
Oudard, S.6
-
130
-
-
77149126422
-
Safety and efficacy results of the advanced renal cell carcinoma sorafenib expanded access program in North America
-
Stadler WM, Figlin RA, McDermott DF, Dutcher JP, Knox JJ, Miller WH Jr, et al. Safety and efficacy results of the advanced renal cell carcinoma sorafenib expanded access program in North America. Cancer 2010; 116:1272-1280.
-
(2010)
Cancer
, vol.116
, pp. 1272-1280
-
-
Stadler, W.M.1
Figlin, R.A.2
McDermott, D.F.3
Dutcher, J.P.4
Knox, J.J.5
Miller Jr., W.H.6
-
131
-
-
79961102885
-
Sunitinib for Asian patients with advanced renal cell carcinoma: A comparable efficacy with different toxicity profiles
-
Kim HS, Hong MH, Kim K, Shin SJ, Ahn JB, Jeung HC, et al. Sunitinib for Asian patients with advanced renal cell carcinoma: a comparable efficacy with different toxicity profiles. Oncology 2011; 80 (5-6):395-405.
-
(2011)
Oncology
, vol.80
, Issue.5-6
, pp. 395-405
-
-
Kim, H.S.1
Hong, M.H.2
Kim, K.3
Shin, S.J.4
Ahn, J.B.5
Jeung, H.C.6
-
132
-
-
79957802759
-
Final results of the European Advanced Renal Cell Carcinoma Sorafenib (EUARCCS) expanded-access study: A large open-label study in diverse community settings
-
Beck J, Procopio G, Bajetta E, Keilholz U, Negrier S, Szczylik C, et al. Final results of the European Advanced Renal Cell Carcinoma Sorafenib (EUARCCS) expanded-access study: a large open-label study in diverse community settings. Ann Oncol 2011; 22:1812-1823.
-
(2011)
Ann Oncol
, vol.22
, pp. 1812-1823
-
-
Beck, J.1
Procopio, G.2
Bajetta, E.3
Keilholz, U.4
Negrier, S.5
Szczylik, C.6
-
133
-
-
84856225907
-
An international expanded-access programme of everolimus: Addressing safety and efficacy in patients with metastatic renal cell carcinoma who progress after initial vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapy
-
REACT Study Group
-
Grünwald V, Karakiewicz PI, Bavbek SE, Miller K, Machiels JP, Lee SH, et al. REACT Study Group. An international expanded-access programme of everolimus: addressing safety and efficacy in patients with metastatic renal cell carcinoma who progress after initial vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapy. Eur J Cancer 2012; 48:324-332.
-
(2012)
Eur J Cancer
, vol.48
, pp. 324-332
-
-
Grünwald, V.1
Karakiewicz, P.I.2
Bavbek, S.E.3
Miller, K.4
Machiels, J.P.5
Lee, S.H.6
-
134
-
-
77449143936
-
Phase III, randomised, multicentre trial of maintenance immunotherapy with low-dose interleukin-2 and interferon-alpha for metastatic renal cell cancer
-
Passalacqua R, Buzio C, Buti S, Porta C, Labianca R, Pezzuolo D, et al. Phase III, randomised, multicentre trial of maintenance immunotherapy with low-dose interleukin-2 and interferon-alpha for metastatic renal cell cancer. Cancer Immunol Immunother 2010; 59:553-561.
-
(2010)
Cancer Immunol Immunother
, vol.59
, pp. 553-561
-
-
Passalacqua, R.1
Buzio, C.2
Buti, S.3
Porta, C.4
Labianca, R.5
Pezzuolo, D.6
-
135
-
-
79959782949
-
Sequential use of sorafenib and sunitinib in advanced renal-cell carcinoma (RCC): An Italian multicentre retrospective analysis of 189 patient cases
-
Porta C, Procopio G, Cartení G, Sabbatini R, Bearz A, Chiappino I, et al. Sequential use of sorafenib and sunitinib in advanced renal-cell carcinoma (RCC): an Italian multicentre retrospective analysis of 189 patient cases. BJU Int 2011; 108 (Pt 2):E250-E257.
-
(2011)
BJU Int
, vol.108
, Issue.PART 2
-
-
Porta, C.1
Procopio, G.2
Cartení, G.3
Sabbatini, R.4
Bearz, A.5
Chiappino, I.6
-
136
-
-
79955489863
-
Outcome of patients with metastatic renal cell carcinoma treated with targeted therapy without cytoreductive nephrectomy
-
Richey SL, Culp SH, Jonasch E, Corn PG, Pagliaro LC, Tamboli P, et al. Outcome of patients with metastatic renal cell carcinoma treated with targeted therapy without cytoreductive nephrectomy. Ann Oncol 2011; 22:1048-1053.
-
(2011)
Ann Oncol
, vol.22
, pp. 1048-1053
-
-
Richey, S.L.1
Culp, S.H.2
Jonasch, E.3
Corn, P.G.4
Pagliaro, L.C.5
Tamboli, P.6
|