메뉴 건너뛰기




Volumn 29, Issue 2, 2012, Pages 799-805

Pioglitazone, etoricoxib, interferon-a, and metronomic capecitabine for metastatic renal cell carcinoma: Final results of a prospective phase II trial

Author keywords

Anti inflammatory agents; C reactive protein; Metastatic renal cell carcinoma; Metronomic chemotherapy; Tumor microenvironment

Indexed keywords

ALPHA INTERFERON; C REACTIVE PROTEIN; CAPECITABINE; ETORICOXIB; PIOGLITAZONE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIDIABETIC AGENT; ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ANTIMETABOLITE; ANTIVIRUS AGENT; CYCLOOXYGENASE 2 INHIBITOR; DEOXYCYTIDINE; DRUG DERIVATIVE; FLUOROURACIL; PYRIDINE DERIVATIVE; SULFONE;

EID: 84866303137     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-011-9982-0     Document Type: Article
Times cited : (30)

References (26)
  • 1
    • 47949096781 scopus 로고    scopus 로고
    • Cancer-related inflammation
    • doi:10.1038/nature07205
    • Mantovani A, Allavena P, Sica A, et al. Cancer-related inflammation. Nature. 2008;454(7203):436-44. doi:10.1038/nature07205.
    • (2008) Nature , vol.454 , Issue.7203 , pp. 436-444
    • Mantovani, A.1    Allavena, P.2    Sica, A.3
  • 2
    • 77954565039 scopus 로고    scopus 로고
    • Inflammation-mediated promotion of invasion, metastasis
    • Solinas G, Marchesi F, Garlanda C, et al. Inflammation-mediated promotion of invasion, metastasis. Cancer Metastasis Rev. 2010; 29(2):243-8.
    • (2010) Cancer Metastasis Rev , vol.29 , Issue.2 , pp. 243-248
    • Solinas, G.1    Marchesi, F.2    Garlanda, C.3
  • 3
    • 70249114110 scopus 로고    scopus 로고
    • Targeting renal cell carcinoma
    • doi:10.1200/JCO.2009.21.8461
    • Motzer RJ, Molina AM. Targeting renal cell carcinoma. J Clin Oncol. 2009;10:3274-6. doi:10.1200/JCO.2009.21.8461.
    • (2009) J Clin Oncol , vol.10 , pp. 3274-3276
    • Motzer, R.J.1    Molina, A.M.2
  • 4
    • 77952300540 scopus 로고    scopus 로고
    • Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): Final analysis of overall survival
    • doi:10.1200/JCO.2009.26.7849
    • Escudier B, Bellmunt J, Négrier S, et al. Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): final analysis of overall survival. J Clin Oncol. 2010;28(13):2144-50. doi:10.1200/JCO.2009.26.7849.
    • (2010) J Clin Oncol , vol.28 , Issue.13 , pp. 2144-2150
    • Escudier, B.1    Bellmunt, J.2    Negrier, S.3
  • 5
    • 77952318310 scopus 로고    scopus 로고
    • Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: Final results of CALGB 90206
    • doi: 10.1200/JCO.2009.26.5561
    • Rini BI, Halabi S, Rosenberg JE, et al. Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: final results of CALGB 90206. J Clin Oncol. 2010;28(13):2137-43. doi: 10.1200/JCO.2009.26.5561.
    • (2010) J Clin Oncol , vol.28 , Issue.13 , pp. 2137-2143
    • Rini, B.I.1    Halabi, S.2    Rosenberg, J.E.3
  • 6
    • 77950312919 scopus 로고    scopus 로고
    • Activity of a multitargeted chemo-switch regimen (sorafenib, gemcitabine, and metronomic capecitabine) in metastatic renal-cell carcinoma: A phase 2 study (SOGUG-02-06)
    • doi:10.1016/S1470-2045(09)70383-3
    • Bellmunt J, Trigo JM, Calvo E. Activity of a multitargeted chemo-switch regimen (sorafenib, gemcitabine, and metronomic capecitabine) in metastatic renal-cell carcinoma: a phase 2 study (SOGUG-02-06). Lancet Oncol. 2010;11(4):350-7. doi:10.1016/S1470-2045(09)70383-3.
    • (2010) Lancet Oncol , vol.11 , Issue.4 , pp. 350-357
    • Bellmunt, J.1    Trigo, J.M.2    Calvo, E.3
  • 7
    • 58649102891 scopus 로고    scopus 로고
    • Systems biology: A therapeutic target for tumor therapy
    • doi: 10.1007/s12307-008-0012-5
    • Reichle A, Vogt T. Systems biology: a therapeutic target for tumor therapy. Cancer Microenviron. 2008;1:159-70. doi: 10.1007/s12307-008-0012-5.
    • (2008) Cancer Microenviron , vol.1 , pp. 159-170
    • Reichle, A.1    Vogt, T.2
  • 8
    • 85128708929 scopus 로고    scopus 로고
    • C-reactive protein in patients with metastatic clear cell renal carcinoma: An important biomarker for tumor-associated inflammation
    • Reichle A, Grassinger J, Bross K, et al. C-reactive protein in Patients with Metastatic Clear Cell Renal Carcinoma: An Important Biomarker for Tumor-associated Inflammation. Biomarker Insights. 2007;1:87-98.
    • (2007) Biomarker Insights , vol.1 , pp. 87-98
    • Reichle, A.1    Grassinger, J.2    Bross, K.3
  • 9
    • 0034594626 scopus 로고    scopus 로고
    • Will there be resistance to the RECIST (response evaluation criteria in solid tumors) J
    • doi:10.1093/jnci/92.3.179
    • Gehan EA, Tefft MC. Will there be resistance to the RECIST (response evaluation criteria in solid tumors) J. Natl Cancer Inst. 2000;92:179-81. doi:10.1093/jnci/92.3.179.
    • (2000) Natl Cancer Inst , vol.92 , pp. 179-181
    • Gehan, E.A.1    Tefft, M.C.2
  • 10
    • 35648936526 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha as a new target for renal cell carcinoma: Two sequential phase II trials of infliximab at standard and high dose
    • doi:10.1200/JCO.2007.11.2136
    • Harrison ML, Obermueller E, Maisey NR, et al. Tumor necrosis factor alpha as a new target for renal cell carcinoma: two sequential phase II trials of infliximab at standard and high dose. J Clin Oncol. 2007;25(29):4542-9. doi:10.1200/JCO.2007.11.2136.
    • (2007) J Clin Oncol , vol.25 , Issue.29 , pp. 4542-4549
    • Harrison, M.L.1    Obermueller, E.2    Maisey, N.R.3
  • 11
    • 70449333312 scopus 로고    scopus 로고
    • Multicenter phase II trial of combination therapy with meloxicam, a cox-2 inhibitor, and natural interferon-alpha for metastatic renal cell carcinoma
    • doi:10.1093/jjco/hyp089
    • Shinohara N, Kumagai A, Kanagawa K, et al. Multicenter phase II trial of combination therapy with meloxicam, a cox-2 inhibitor, and natural interferon-alpha for metastatic renal cell carcinoma. Jpn J Clin Oncol. 2009;39(11):720-6. doi:10.1093/jjco/hyp089.
    • (2009) Jpn J Clin Oncol , vol.39 , Issue.11 , pp. 720-726
    • Shinohara, N.1    Kumagai, A.2    Kanagawa, K.3
  • 12
    • 31544455868 scopus 로고    scopus 로고
    • Maximal COX-2 immunostaining and clinical response to celecoxib and interferon alpha therapy in metastatic renal cell carcinoma
    • doi:10.1002/cncr.21661
    • Rini BI, Weinberg V, Dunlap S, et al. Maximal COX-2 immunostaining and clinical response to celecoxib and interferon alpha therapy in metastatic renal cell carcinoma. Cancer. 2006;106(3): 566-75. doi:10.1002/cncr.21661.
    • (2006) Cancer , vol.106 , Issue.3 , pp. 566-575
    • Rini, B.I.1    Weinberg, V.2    Dunlap, S.3
  • 13
    • 0028985427 scopus 로고
    • Interferon-alpha induces circulating tumor necrosis factor receptor p55 in humans
    • Tilg H, Vogel W, Dinarello CA. Interferon-alpha induces circulating tumor necrosis factor receptor p55 in humans. Blood. 1995;85:433-5.
    • (1995) Blood , vol.85 , pp. 433-435
    • Tilg, H.1    Vogel, W.2    Dinarello, C.A.3
  • 14
    • 0037235020 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma and cancers
    • Koeffler HP. Peroxisome proliferator-activated receptor gamma and cancers. Clin Cancer Res. 2003;9(1):1-9.
    • (2003) Clin Cancer Res , vol.9 , Issue.1 , pp. 1-9
    • Koeffler, H.P.1
  • 15
    • 25144475465 scopus 로고    scopus 로고
    • PPAR-gamma as a therapeutic target for tumor angiogenesis and metastasis
    • Panigrahy D, Huang S, Kieran MW, et al. PPAR-gamma as a therapeutic target for tumor angiogenesis and metastasis. Cancer Biol Ther. 2005;4:687-93.
    • (2005) Cancer Biol Ther , vol.4 , pp. 687-693
    • Panigrahy, D.1    Huang, S.2    Kieran, M.W.3
  • 16
    • 23844552830 scopus 로고    scopus 로고
    • New indications for established drugs: Combined tumor-stroma-targeted cancer therapy with PPARc agonists, COX-2 inhibitors, mTOR antagonists and metronomic chemotherapy
    • Hafner C, Reichle A, Vogt T. New indications for established drugs: combined tumor-stroma-targeted cancer therapy with PPARc agonists, COX-2 inhibitors, mTOR antagonists and metronomic chemotherapy. Current Cancer Drug Targets. 2005; 5(6):393-419.
    • (2005) Current Cancer Drug Targets , vol.5 , Issue.6 , pp. 393-419
    • Hafner, C.1    Reichle, A.2    Vogt, T.3
  • 17
    • 75149185211 scopus 로고    scopus 로고
    • The role of PPARc in the cyclooxygenase pathway in lung cancer
    • doi: 10.1155/2008/790568
    • Hazra S, Peebles KA, Sharma S et al. The role of PPARc in the cyclooxygenase pathway in lung cancer. PPAR Res 2008 doi: 10.1155/2008/790568.
    • (2008) PPAR Res
    • Hazra, S.1    Peebles, K.A.2    Sharma, S.3
  • 18
    • 0035214416 scopus 로고    scopus 로고
    • Metronomic scheduling: The future of chemotherapy?
    • doi:10.1016/S1470-2045 (01)00587-3
    • Gasparini G. Metronomic scheduling: the future of chemotherapy? Lancet Oncol. 2001;2(12):733-40. doi:10.1016/S1470-2045 (01)00587-3.
    • (2001) Lancet Oncol , vol.2 , Issue.12 , pp. 733-740
    • Gasparini, G.1
  • 19
    • 77951914543 scopus 로고    scopus 로고
    • A phase-II study of combination of pegylated interferon alfa-2a and capecitabine in locally advanced or metastatic renal cell cancer
    • doi:10.1007/s00280-009-1134-2
    • Sunela KL, Koskinen S, Kellokumpu-Lehtinen P. A phase-II study of combination of pegylated interferon alfa-2a and capecitabine in locally advanced or metastatic renal cell cancer. Cancer Chemother Pharmacol. 2010;66(1):59-67. doi:10.1007/s00280-009-1134-2.
    • (2010) Cancer Chemother Pharmacol , vol.66 , Issue.1 , pp. 59-67
    • Sunela, K.L.1    Koskinen, S.2    Kellokumpu-Lehtinen, P.3
  • 20
    • 0031415831 scopus 로고    scopus 로고
    • Serum interleukin-6 in relation to acute-phase reactants and survival in patients with renal cell carcinoma
    • doi:10.1016/S0959-8049(97)00179-2
    • Ljungberg B, Grankvist K, Rasmuson T. Serum interleukin-6 in relation to acute-phase reactants and survival in patients with renal cell carcinoma. Eur J Cancer. 1997;33:1794-8. doi:10.1016/S0959-8049(97)00179-2.
    • (1997) Eur J Cancer , vol.33 , pp. 1794-1798
    • Ljungberg, B.1    Grankvist, K.2    Rasmuson, T.3
  • 21
    • 6944225501 scopus 로고    scopus 로고
    • The systemic inflammatory response, performance status and survival in patients undergoing alpha-interferon treatment for advanced renal cancer
    • doi:10.1038/sj.bjc. 6602152
    • Bromwich E, McMillan DC, Lamb GW, et al. The systemic inflammatory response, performance status and survival in patients undergoing alpha-interferon treatment for advanced renal cancer. Br J Cancer. 2004;91:1236-8. doi:10.1038/sj.bjc. 6602152.
    • (2004) Br J Cancer , vol.91 , pp. 1236-1238
    • Bromwich, E.1    McMillan, D.C.2    Lamb, G.W.3
  • 22
    • 62649130234 scopus 로고    scopus 로고
    • Impact of C-reactive protein kinetics on survival of patients with metastatic renal cell carcinoma
    • doi:10.1016/j.eururo.2008. 10.012
    • Saito K, Tatokoro M, Fujii Y, et al. Impact of C-reactive protein kinetics on survival of patients with metastatic renal cell carcinoma. Eur Urol. 2009;55:1145-53. doi:10.1016/j.eururo.2008. 10.012.
    • (2009) Eur Urol , vol.55 , pp. 1145-1153
    • Saito, K.1    Tatokoro, M.2    Fujii, Y.3
  • 23
    • 73749086365 scopus 로고    scopus 로고
    • Absolute preoperative C-reactive protein predicts metastasis and mortality in the first year following potentially curative nephrectomy for clear cell carcinoma
    • Johnson TV, Abbas A, Owen-Smith A, et al. Absolute preoperative C-reactive protein predicts metastasis and mortality in the first year following potentially curative nephrectomy for clear cell carcinoma. J Urol. 2010;193:480-5.
    • (2010) J Urol , vol.193 , pp. 480-485
    • Johnson, T.V.1    Abbas, A.2    Owen-Smith, A.3
  • 24
    • 59349103887 scopus 로고    scopus 로고
    • Development and external validation of a new outcome prediction model for patients with clear cell renal cell carcinoma treated with nephrectomy based on preoperative serum C-reactive protein and TNM classification: The TNM-C score
    • Limura Y, Saito K, Fujii Y, et al. Development and external validation of a new outcome prediction model for patients with clear cell renal cell carcinoma treated with nephrectomy based on preoperative serum C-reactive protein and TNM classification: the TNM-C score. J Urol. 2009;181:1004-12.
    • (2009) J Urol , vol.181 , pp. 1004-1012
    • Limura, Y.1    Saito, K.2    Fujii, Y.3
  • 25
    • 2342515336 scopus 로고    scopus 로고
    • Thalidomide reduces serum C-reactive protein and interleukin-6 and induces response to IL-2 in a fraction of metastatic renal cell cancer patients who failed IL-2- based therapy
    • doi: 10.1002/ijc.20089
    • Kedar I, Mermershtain W, Ivgi H, et al. Thalidomide reduces serum C-reactive protein and interleukin-6 and induces response to IL-2 in a fraction of metastatic renal cell cancer patients who failed IL-2- based therapy. Int J Cancer. 2004;110:260-5. doi: 10.1002/ijc.20089.
    • (2004) Int J Cancer , vol.110 , pp. 260-265
    • Kedar, I.1    Mermershtain, W.2    Ivgi, H.3
  • 26
    • 33645761710 scopus 로고    scopus 로고
    • Inflammatory response predicts survival in renal cancer
    • doi:10.1016/S1470-2045(06)70632-5
    • Kerr C. Inflammatory response predicts survival in renal cancer. Lancet Oncol. 2006;7:284. doi:10.1016/S1470-2045(06)70632-5.
    • (2006) Lancet Oncol , vol.7 , pp. 284
    • Kerr, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.